Research_

Sharpe Lab

Transforming our understanding of how the brain forms memories
The Sharpe Lab is a research group committed to understanding the cognitive models of our environment based on past experiences. We hope to understand how the brain learns (and forms memories) about information so we can understand when this goes wrong in psychopathology.

Our research explores how we can build cognitive models from learned associations across various brain regions, with a focus on the central role of the ventral tegmental area (VTA) in driving learning through dopamine signalling, and the lateral hypothalamus in storing learned associations.

We investigate how disruptions in these processes contribute to disorders like schizophrenia, addiction, anxiety and post-traumatic stress disorder (PTSD), aiming to develop targeted therapies to enhance patient outcomes.

Learn more about our research.

Our people

We have a range of people with differential expertise at different career stages that are working together to understand the brain. This allows us to conduct research across a number of different techniques with differing perspectives. 

  • Dr Masakazu Taira, Postdoctoral Fellow
  • Dr Arvie Abiero, Postdoctoral Fellow
  • Dr Kiruthika Ganesan, Postdoctoral Fellow
  • Dr Jessica Leake, Postdoctoral Fellow
  • Adrian Dawson, Honours Student/Research Assistant

Join us

We are accepting graduate students and are always open to postdocs applying to join our team. If you’re interested in working within our team, contact Mel at melissa.sharpe@sydney.edu.au with a brief description of your background, expertise, and research interests in the context of our umbrella of research.


Image on this page courtesy of Anna Beyeler

Research Head

Dr Melissa Sharpe headshot
Dr Melissa Sharpe
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