Mrs Hilary Byrne


Biographical details

Dr Byrne obtained a first class MSci in Physics from the University of Cambridge. She had experience in the software development industry before obtaining a PhD in Medical Physics from the University of Sydney in 2017. She is currently in a postdoctoral research position.

Research interests

Research Interests are:

  • Monte Carlo simulation, particularly subcellular radiation damage;
  • radiation biophysics;
  • nanodosimetry; nanoparticle radiosensitisation;
  • theranostics

Teaching and supervision

Dr Byrne has supervised undergraduate SSP projects in the School of Physics. She has experience in undergraduate tutoring and preparing resources for HSC teachers.

Current projects

Nanoparticle radiosensitisation

Investigating gadolinium-based nanoparticles for radiosensitisation and MRI contrast. This enables enhanced cancer treatment with confirmation of nanoparticle uptake at time of treatment on novel combined MRI-linac systems.

In collaboration with the Australian MRI-linac project and the Ingham Institute for Applied Medical Research.

Awards and honours

Dr Byrne was awarded the 2018 Sydney Vital Fellowship in Nanotechnology.

In the media

Selected publications

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Journals

  • Byrne, H., Gholami, Y., Kuncic, Z. (2017). Impact of fluorescence emission from gold atoms on surrounding biological tissue - Implications for nanoparticle radio-enhancement. Physics in Medicine and Biology, 62(8), 3097-3110. [More Information]
  • McNamara, A., Kam, W., Scales, N., McMahon, S., Bennett, J., Byrne, H., Schuemann, J., Paganetti, H., Banati, R., Kuncic, Z. (2016). Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol. Physics in Medicine and Biology, 61(16), 5993-6010. [More Information]
  • Byrne, H., Domanova, W., McNamara, A., Incerti, S., Kuncic, Z. (2015). The cytoplasm as a radiation target: An in silico study of microbeam cell irradiation. Physics in Medicine and Biology, 60(6), 2325-2337. [More Information]
  • Byrne, H., McNamara, A., Domanova, W., Guatelli, S., Kuncic, Z. (2013). Radiation damage on sub-cellular scales: beyond DNA. Physics in Medicine and Biology, 58(5), 1251-1267. [More Information]
  • Kuncic, Z., Byrne, H., McNamara, A., Guatelli, S., Domanova, W., Incerti, S. (2012). In Silico Nanodosimetry: New Insights into Nontargeted Biological Responses to Radiation. Computational and Mathematical Methods in Medicine, 2012, 1-9. [More Information]

2017

  • Byrne, H., Gholami, Y., Kuncic, Z. (2017). Impact of fluorescence emission from gold atoms on surrounding biological tissue - Implications for nanoparticle radio-enhancement. Physics in Medicine and Biology, 62(8), 3097-3110. [More Information]

2016

  • McNamara, A., Kam, W., Scales, N., McMahon, S., Bennett, J., Byrne, H., Schuemann, J., Paganetti, H., Banati, R., Kuncic, Z. (2016). Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol. Physics in Medicine and Biology, 61(16), 5993-6010. [More Information]

2015

  • Byrne, H., Domanova, W., McNamara, A., Incerti, S., Kuncic, Z. (2015). The cytoplasm as a radiation target: An in silico study of microbeam cell irradiation. Physics in Medicine and Biology, 60(6), 2325-2337. [More Information]

2013

  • Byrne, H., McNamara, A., Domanova, W., Guatelli, S., Kuncic, Z. (2013). Radiation damage on sub-cellular scales: beyond DNA. Physics in Medicine and Biology, 58(5), 1251-1267. [More Information]

2012

  • Kuncic, Z., Byrne, H., McNamara, A., Guatelli, S., Domanova, W., Incerti, S. (2012). In Silico Nanodosimetry: New Insights into Nontargeted Biological Responses to Radiation. Computational and Mathematical Methods in Medicine, 2012, 1-9. [More Information]

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