A fundamental understanding of disease and dysfunction is critical to applying principles of preventative and therapeutic interventions in veterinary practice. This unit of study provides a thorough grounding in knowledge and skills for a wide range of veterinary disciplines including veterinary pathology, veterinary clinical pathology, immunology, veterinary microbiology, veterinary parasitology, animal behaviour, veterinary pharmacology and veterinary diagnostic imaging. An integrated multi-disciplinary approach will highlight the underlying pathophysiology and aetiopathogenesis of clinical and subclinical disease affecting several major body systems. This unit will emphasise a pathobiological approach to investigations providing a logical diagnostic framework to facilitate students' understanding of disease and disease investigation. This unit of study will utilise scenarios from companion animals, production animals and wildlife to contextualise problems involving haematology, disorders of growth, dermatopathology, gastrointestinal pathology, urinary system pathology and endocrine system pathology as well as behavioural manifestations during disease. The use of case-based scenarios will motivate and direct students to develop the concepts and principles underscoring therapeutics and disease control and management programs. The unit provides the foundation for integrated parasite/pest management (IPM) strategies. In addition, vector-, water- and food- borne diseases and transboundary diseases will be included enabling students to understand their relevance to the human-animal bond, public health, trade and biosecurity. Reinforcing the development and maintenance of normal structure and function will highlight abnormalities associated with specific clinical presentations and disease entities. This unit of study integrates with the concepts and skills taught within VETS6203 (Research and Enquiry 2A) and VETS6202 (Professional skills 2A) to prepare students for the clinical units of study in DVM 3.