Table 1: Nutrition and Metabolism

Errata
Item Errata Date
1. Prerequisites have changed for the following units. They now read:

BCHM3071 Molecular Biology and Biochem-Genes Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71 or MEDS2003)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]

BCHM3971 Molecular Biology and Biochem-Genes (Adv) Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71 or MEDS2003)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
20/2/2019
2.

Prerequisites have changed for the following units. They now read:

BCHM3081 Mol Biology and Biochemistry-Proteins  Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71 or MEDS2003)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]

BCHM3981 Mol Biology and Biochem-Proteins (Adv) Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71 or MEDS2003)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
11/3/2019

Unit of study Credit points A: Assumed knowledge P: Prerequisites C: Corequisites N: Prohibition Session

Nutrition and Metabolism

For a major in Nutrition and Metabolism, the minimum requirement is 24 credit points from senior units of study listed in this subject area which must include NUTM3001 and NUTM3888.
Junior units of study
BIOL1006
Life and Evolution
6    A HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February).
N BIOL1001 or BIOL1911 or BIOL1991 or BIOL1906 or BIOL1996
Semester 1
BIOL1906
Life and Evolution (Advanced)
6    A 85 or above in HSC Biology or equivalent.
N BIOL1001 or BIOL1911 or BIOL1991 or BIOL1006 or BIOL1996

Note: Department permission required for enrolment

Semester 1
BIOL1996
Life and Evolution (SSP)
6    A 90 or above in HSC Biology or equivalent
N BIOL1001 or BIOL1911 or BIOL1991 or BIOL1006 or BIOL1906 or BIOL1993 or BIOL1998

Note: Department permission required for enrolment

Semester 1
BIOL1007
From Molecules to Ecosystems
6    A HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February).
N BIOL1907 or BIOL1997
Semester 2
BIOL1907
From Molecules to Ecosystems (Advanced)
6    A 85 or above in HSC Biology or equivalent
N BIOL1007 or BIOL1997

Note: Department permission required for enrolment

Semester 2
BIOL1997
From Molecules to Ecosystems (SSP)
6    A 90 or above in HSC Biology or equivalent
N BIOL1007 or BIOL1907

Note: Department permission required for enrolment

Semester 2
Intermediate units of study
BCMB2001
Biochemistry and Molecular Biology
6    P 6cp of (BIOL1XX7 or MBLG1XXX) and 6cp of (CHEM1XX1 or CHEM1903)
N BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2901 or MEDS2003
Semester 1
BCMB2901
Biochemistry and Molecular Biology (Advanced)
6    P A mark of at least 70 from (BIOL1XX7 or MBLG1XX1) and (CHEM1XX1 or CHEM1903)
N BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or MEDS2003
Semester 1
PHSI2007
Key Concepts in Physiology
6    A Human biology
P 6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]
N PHSI2907 or BMED2402 or MEDS2001
Semester 1
PHSI2907
Key Concepts in Physiology (Advanced)
6    A Human biology
P A mark of 70 or above in {6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]}
N PHSI2007 or BMED2402 or MEDS2001

Note: Department permission required for enrolment

Semester 1
PHSI2008
Integrated Physiology
6    A Human biology; (PHSI2X07 or MEDS2001)]
P [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]}
N PHSI2908
Semester 2
PHSI2908
Integrated Physiology (Advanced)
6    A Human biology; (PHSI2X07 or MEDS2001)]
P A mark of 70 or above in {6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]}
N PHSI2008

Note: Department permission required for enrolment

Semester 2
Senior core units of study
Students must complete both NUTM3001 and NUTM3888.
NUTM3001
Introductory Nutrition and Metabolism
6    A PHSI2X05 and PHSI2X06
P [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 1
NUTM3888
Metabolic Cybernetics
6    A PHSI2X0X and (MATH1XX5 or ATHK1001)
P [(BCHM2X72 or BCMB2X01 or MEDS2003) and (BCHM2X71 or BCMB2X02 or DATA2002 or GEGE2X01 or MBLG2X7X or BIOL2XXX or PHSI2X0X or MEDS2001)] or (BMED2401 and BMED2405)
N NUTM3004 or NUTM3002
Semester 2
Senior elective units of study
BCHM3071
Molecular Biology and Biochemistry-Genes
6    P [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3971


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 1
BCHM3971
Molecular Biology and Biochem-Genes (Adv)
6    P [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3071


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 1
BCHM3081
Mol Biology and Biochemistry-Proteins
6    P [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3981


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 1
BCHM3981
Mol Biology and Biochem-Proteins (Adv)
6    P [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3081


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 1
BCHM3072
Human Molecular Cell Biology
6    P [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3972


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 2
BCHM3972
Human Molecular Cell Biology (Advanced)
6    P [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3072


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 2
BCHM3082
Medical and Metabolic Biochemistry
6    P [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3982


BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Semester 2
BCHM3982
Medical and Metabolic Biochemistry (Adv)
6    P [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]
N BCHM3082
Semester 2
PHSI3009
Frontiers in Cellular Physiology
6    P (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [BMED2401 and an additional 12cp from (BMED2402 or BMED2403 or BMED2405 or BMED2406)]
N PHSI3905 or PHSI3906 or PHSI3005 or PHSI3006 or PHSI3909


We strongly recommend that students take both (PHSI3009 or PHSI3909) and (PHSI3010 or PHSI3910) units of study concurrently
Semester 1
PHSI3909
Frontiers in Cellular Physiology (Adv)
6    P A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BMED2402 or BMED2403 or BMED2406)]}
N PHSI3009 or PHSI3005 or PHSI3905 or PHSI3006 or PHSI3906
Semester 1
PHSI3010
Reproduction, Development and Disease
6    P (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BCMB2X02 or BIOL2X29 or GEGE2X01)] or [12cp from (BMED2402 or BMED2403 or BMED2406)]
N PHSI3905 or PHSI3906 or PHSI3005 or PHSI3006 or PHSI3910
Semester 1
PHSI3910
Reproduction, Development and Disease Adv
6    P A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BCMB2X02 or BIOL2X29 or GEGE2X01)] or [12cp from (BMED2402 or BMED2403 or BMED2406)]}
N PHSI3010 or PHSI3005 or PHSI3905 or PHSI3006 or PHSI3906
Semester 1
PHSI3012
Physiology of Disease
6    P (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or 12cp from (BMED2402 or BMED2403 or BMED2404 or BMED2406)
N PHSI3007 or PHSI3008 or PHSI3907 or PHSI3908 or PHSI3912
Semester 2
PHSI3912
Physiology of Disease (Advanced)
6    P A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or 12cp from (BMED2402 or BMED2403 or BMED2404 or BMED2406)
N PHSI3012 or PHSI3007 or PHSI3907 or PHSI3008 or PHSI3908
Semester 2

Nutrition and Metabolism

For a major in Nutrition and Metabolism, the minimum requirement is 24 credit points from senior units of study listed in this subject area which must include NUTM3001 and NUTM3888.
Junior units of study
BIOL1006 Life and Evolution

Credit points: 6 Teacher/Coordinator: Dr Matthew Pye, A/Prof Charlotte Taylor Session: Semester 1 Classes: Two lectures per week; 11 x 3-hour lab classes; a field excursion Prohibitions: BIOL1001 or BIOL1911 or BIOL1991 or BIOL1906 or BIOL1996 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: Writing task (10%), laboratory report (20%), laboratory notebook (10%), during semester tests and quizzes (20%), summative final exam (40%) Practical field work: 11 x 3-hour lab classes, a field excursion Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, proteins) to whole ecosystems in which myriads of species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. This unit explores how new species continue to arise while others go extinct and discusses the role of mutations as the raw material on which selection acts. It explains how information is transferred between generations through DNA, RNA and proteins, transformations which affect all aspects of biological form and function. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. You will participate in inquiry-led practical classes investigating single-celled organisms and the diversity of form and function in plants and animals. By doing this unit of study, you will develop the ability to examine novel biological systems and understand the complex processes that have shaped those systems.
Textbooks
Knox, B., Ladiges, P.Y., Evans, B.K., Saint, R. (2014) Biology: an Australian focus, 5e, McGraw-Hill education, North Ryde, N.S.W
BIOL1906 Life and Evolution (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Matthew Pye, A/Prof Charlotte Taylor Session: Semester 1 Classes: Two lectures per week; 11 x 3-hour lab classes; a field excursion Prohibitions: BIOL1001 or BIOL1911 or BIOL1991 or BIOL1006 or BIOL1996 Assumed knowledge: 85 or above in HSC Biology or equivalent. Assessment: Writing task (10%), project report (20%), laboratory notebook (10%), during semester tests and quizzes (20%), summative final exam (40%) Practical field work: 11 x 3-hour lab classes, a field excursion Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, proteins) to whole ecosystems in which myriads of species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. This unit explores how new species continue to arise while others go extinct and discusses the role of mutations as the raw material on which selection acts. It explains how information is transferred between generations through DNA, RNA and proteins, transformations which affect all aspects of biological form and function. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. You will participate in inquiry-led practical classes investigating single-celled organisms and the diversity of form and function in plants and animals.
Life and Evolution (Advanced) has the same overall structure as BIOL1006 but material is discussed in greater detail and at a more advanced level. Students enrolled in BIOL1906 participate in a research project with a focus on developing skills in critical evaluation, experimental design, data analysis and communication.
Textbooks
Knox, B., Ladiges, P.Y., Evans, B.K., Saint, R. (2014) Biology: an Australian focus, 5e, McGraw-Hill education, North Ryde, N.S.W
BIOL1996 Life and Evolution (SSP)

Credit points: 6 Teacher/Coordinator: Dr Mark de Bruyn Session: Semester 1 Classes: Lectures as per BIOL1906; one 3-hour practical per week Prohibitions: BIOL1001 or BIOL1911 or BIOL1991 or BIOL1006 or BIOL1906 or BIOL1993 or BIOL1998 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (50%), practical reports (25%), seminar presentation (15%), lab note book (5%), prelaboratory quizzes (5%) Practical field work: null Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Biology is an immensely diverse science. Biologists study life at all levels, from the fundamental building blocks (genes, and proteins) to whole ecosystems in which myriad species interact. Evolution is the unifying concept that runs through the life sciences, from the origin and diversification of life to understanding behaviour, to dealing with disease. Evolution through natural selection is the framework in biology in which specific details make sense. Science builds and organises knowledge of life and evolution in the form of testable hypotheses. The practical work syllabus for BIOL1996 is different from that of BIOL1906 (Advanced) and consists of a special project-based laboratory.
Textbooks
Please see unit outline on LMS
BIOL1007 From Molecules to Ecosystems

Credit points: 6 Teacher/Coordinator: Dr Emma Thompson Session: Semester 2 Classes: Two lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1907 or BIOL1997 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: Quizzes (10%), communication assessments (40%), skills tests (10%), summative final exam (40%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . You will participate in inquiry-led practicals that reinforce the concepts in the unit. By doing this unit you will develop knowledge and skills that will enable you to play a role in finding global solutions that will impact our lives.
Textbooks
Please see unit outline on LMS
BIOL1907 From Molecules to Ecosystems (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Claudia Keitel Session: Semester 2 Classes: Two lectures per week and online material and 12 x 3-hour practicals Prohibitions: BIOL1007 or BIOL1997 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: Quizzes (10%), communication assessments (40%), skills tests (10%), summative exam (40%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . This unit of study has the same overall structure as BIOL1007 but material is discussed in greater detail and at a more advanced level. The content and nature of these components may vary from year to year.
Textbooks
Please see unit outline on LMS
BIOL1997 From Molecules to Ecosystems (SSP)

Credit points: 6 Teacher/Coordinator: Dr Emma Thompson Session: Semester 2 Classes: Two lectures per week and online material Prohibitions: BIOL1007 or BIOL1907 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: One 2-hour exam (40%), project report which includes written report and presentation (60%) Practical field work: As advised and required by the project; approximately 30-36 hours of research project in the laboratory or field Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and intervene in ecosystems to improve health. The same theory will be covered as in the advanced stream but in this Special Studies Unit, the practical component is a research project. The research will be a synthetic biology project investigating genetically engineered organisms. Students will have the opportunity to develop higher level generic skills in computing, communication, critical analysis, problem solving, data analysis and experimental design.
Textbooks
Please see unit outline on LMS
Intermediate units of study
BCMB2001 Biochemistry and Molecular Biology

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: 6cp of (BIOL1XX7 or MBLG1XXX) and 6cp of (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2901 or MEDS2003 Assessment: Assignments, skills-based assessment, quizzes, exam Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the life and medical sciences.
Textbooks
Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9
BCMB2901 Biochemistry and Molecular Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Dale Hancock Session: Semester 1 Classes: Three lectures per week; one 4-hour practical and one 1-hour tutorial session per fortnight Prerequisites: A mark of at least 70 from (BIOL1XX7 or MBLG1XX1) and (CHEM1XX1 or CHEM1903) Prohibitions: BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or MEDS2003 Assessment: Assignments, quiz, skills-based assessment, exam Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? And, what happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how the use of fuels is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. The advanced laboratory component will provide students with an authentic research laboratory experience while in the theory component, current research topics will be presented in a problem-based format through dedicated advanced tutorial sessions. This material will be assessed by creative student-centered activities supported by eLearning platforms.
Textbooks
Stryer Biochemistry 8th Edition ISBN-13:978-1-4641-2610-9
PHSI2007 Key Concepts in Physiology

Credit points: 6 Teacher/Coordinator: Dr Tara Speranza Session: Semester 1 Classes: 2 (1hr) lectures, 1 (1hr) lectorials and either (1) (3 hr) lab or a 2 hour workshop. Prerequisites: 6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903] Prohibitions: PHSI2907 or BMED2402 or MEDS2001 Assumed knowledge: Human biology Assessment: Quizzes (10%), 90 min MCQ exam (30%), Written and other tasks: Integrated Science project task (10%) , Laboratory report writing (25%), How Physiology Works (15%), Explaining Physiology (10% group) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Physiology plays a central role in the medical sciences, integrating from the molecular and cellular levels through to the whole tissue and organs to understand whole body function. The study of physiology involves learning core concepts and principles that are applied to the various organ systems. You will be able to apply these fundamentals as you learn about other organ systems and how their homeostatic interactions govern human body function. To support your learning, you will undertake laboratory activities that involve experiments on humans as well as isolated tissues, with an emphasis on hypothesis generation and data analysis. These sessions will consolidate your conceptual understanding with practical application of core physiological principles in an experimental context. Additional workshops and tutorials will develop critical thinking, understanding of the integrative nature of physiology, and generic skills in scientific writing and presentation. The practicals and tutorials also emphasise group learning and team work. Completion of this unit will provide you with a strong foundational understanding of the homeostatic principles that underpin whole body physiology.
PHSI2907 Key Concepts in Physiology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Tara Speranza Session: Semester 1 Classes: 2 (1hr) lectures, 1 (1hr) lectorials and either (1) (3 hr) lab or a 2 hour workshop. Prerequisites: A mark of 70 or above in {6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]} Prohibitions: PHSI2007 or BMED2402 or MEDS2001 Assumed knowledge: Human biology Assessment: Quizzes (10%), 90 min MCQ exam (30%), Video submission of cell communication (25%), Laboratory report writing (25%), Explaining Physiology (10% group) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Physiology plays a central role in the medical sciences, integrating the molecular and cellular levels through to the whole tissue and organs to understand whole body function. The study of physiology involves learning core concepts and principles that are applied to the various organ systems. You will explore these concepts in four modules: compartmentalisation, cell specialisation, communication between cells and responding to the environment. You will be able to apply these fundamentals as you learn about other organs systems and how their homeostatic interactions govern human body function. To support your learning you will undertake laboratory activities that involve experiments on humans as well as isolated tissues, with an emphasis on hypothesis generation and data analysis. These sessions will consolidate your conceptual understanding with practical application of core physiological principles in an experimental context. Furthermore, specialised activities in physiological research will allow small group learning and interaction with staff. Workshops and tutorials will develop critical thinking, understanding of the integrative nature of physiology, and generic skills in scientific writing and presentation. The practicals and tutorials also emphasise group learning and team work. Completion of this unit will provide you with a strong foundational understanding of the homeostatic principles that underpin whole body physiology.
PHSI2008 Integrated Physiology

Credit points: 6 Teacher/Coordinator: A/Prof Bronwyn McAllan Session: Semester 2 Classes: 2 (1hr) lectures, 1 (1hr) lectorials and either (1) (3 hr) lab or a 2 hour workshop. Prerequisites: [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]} Prohibitions: PHSI2908 Assumed knowledge: Human biology; (PHSI2X07 or MEDS2001)] Assessment: Quizzes (10%), 90 min MCQ exam (30%), Written and other tasks (10%), Laboratory report writing (25%), How Physiology Works (15%), Explaining Physiology (10% group) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The study of physiology is in essence the understanding of the integration of function and homeostasis. In this unit you will extend your learning in MEDS2001/PHSI2X07, applying your understanding of basic physiology to systems-based scenarios in three modules: muscle, sensory and disease complications. This will consolidate your conceptual understanding of physiology and how the homeostatic mechanisms change in disease. The final module on disease will consolidate your understanding by demonstrating how body systems do not act in isolation, but rather how changes in their interdependence lead to homeostatic dysregulation and pathological outcomes. To support your learning you will undertake laboratory activities that involve experiments on humans as well isolated tissues, with an emphasis on hypothesis generation and data analysis. These sessions will consolidate your conceptual understanding with practical application of core physiological principles in an experimental context. Additional workshops and tutorials will develop critical thinking, your understanding of the integrative nature of physiology, and generic skills in scientific writing and presentation. The practicals and tutorials also emphasise group learning and team work. Completion of this unit will provide you with a comprehensive understanding of the complex systems that regulate the human body and provide the platform for undertaking a major in Physiology in third year.
PHSI2908 Integrated Physiology (Advanced)

Credit points: 6 Teacher/Coordinator: Prof Peter Thorn Session: Semester 2 Classes: 2 (1hr) lectures, 1 (1hr) lectorials and either (1) (3 hr) lab or a 2 hour workshop. Prerequisites: A mark of 70 or above in {6cp from [(MEDS1X01 or BIOL1XX8 or BIOL1XX3) or (BIOL1XX7 or MBLG1XX1) or CHEM1XX1 or CHEM1903]} Prohibitions: PHSI2008 Assumed knowledge: Human biology; (PHSI2X07 or MEDS2001)] Assessment: Quizzes (10%), 90 min MCQ exams (30%), Written and other tasks (25%), Laboratory report writing (25%), Explaining Physiology (10% group) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
The study of physiology is in essence the understanding of the integration of function and homeostasis. In this unit you will extend your learning in MEDS2001/PHSI2X07 by applying your understanding of basic physiology to systems-based scenarios in three modules: muscle, sensory and disease complications. This will consolidate your conceptual understanding of physiology and how the homeostatic mechanisms change in disease. The final module on disease will consolidate your understanding by demonstrating how body systems do not act isolation, but rather how changes in their interdependence lead to homeostatic dysregulation and pathological outcomes. This unit of study will extend the PHSI2008 unit. Activities will focus on current research in the area of physiology, including examples of its relevance to disease. Students will engage with active researchers and explore the role of physiology in multidisciplinary approaches to understanding body function. To support your learning you will undertake laboratory activities that involve experiments on humans as well isolated tissues, with an emphasis on hypothesis generation and data analysis. These sessions will consolidate your conceptual understanding with practical application of core physiological principles in an experimental context. Additional workshops and tutorials will develop critical thinking, your understanding of the integrative nature of physiology, and generic skills in scientific writing and presentation. The practicals and tutorials also emphasise group learning and team work and provide an opportunity for students to apply and extend their understanding of physiological concepts. Completion of this unit will provide you with a comprehensive understanding of the complex systems that regulate the human body and provide the platform for undertaking a major in Physiology in third year.
Senior core units of study
Students must complete both NUTM3001 and NUTM3888.
NUTM3001 Introductory Nutrition and Metabolism

Credit points: 6 Teacher/Coordinator: Wendy Stuart-Smith Session: Semester 1 Classes: Two lectures, one tutorial per week, 1-5hour laboratory/presentation class most weeks Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Assumed knowledge: PHSI2X05 and PHSI2X06 Assessment: In semester reports, presentations and quizzes (40%) one 2.5-hour exam (60%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
Nutrition is a multidisciplinary science that covers the role of food in health and disease. Advances in biomolecular science have increased the focus of nutrition on the metabolic pathways that transform nutrients. This unit of study aims to explore fundamentals in nutritional science to develop an understanding of the core concepts in human nutrition through exploring the role of macro- and micro-nutrients and their interaction across the lifespan, mostly in the healthy individual. The focus will be the biochemical reactions that take place in cells, how these are influenced by different nutrients and what are the implications for the whole body. This unit of study will consider the structure and chemical characteristics of nutrients, their metabolism, and their roles in health and disease. This unit of study will explore how animal models, cell culture techniques and human trials have contributed to advancing nutritional science. Examples from current research will be used to illustrate how nutrients are metabolised, mostly in health, and the expanding scope of research in human nutrition.
Textbooks
Essentials of Human Nutrition 4th Edition, 2012. Edited by Jim Mann and A. Stewart Truswell. Oxford University Press. ISBN: 9780199566341*
NUTM3888 Metabolic Cybernetics

Credit points: 6 Teacher/Coordinator: Dr Kim Bell-Anderson Session: Semester 2 Classes: lectures 2hrs/week; tutorial 1hr/week; practical 2hr/week Prerequisites: [(BCHM2X72 or BCMB2X01 or MEDS2003) and (BCHM2X71 or BCMB2X02 or DATA2002 or GEGE2X01 or MBLG2X7X or BIOL2XXX or PHSI2X0X or MEDS2001)] or (BMED2401 and BMED2405) Prohibitions: NUTM3004 or NUTM3002 Assumed knowledge: PHSI2X0X and (MATH1XX5 or ATHK1001) Assessment: One 1.5hr exam (30%), 1000w essay (10%), data visualisation exercises (10%), research project 50% (multimedia group work (20%), presentation group work (15%), 500w student re?ection (5%), mentor assessment (5%), report (5%)) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Obesity is a worldwide health problem driven by a complex intersection between genetics and the environment. This interdisciplinary unit of study aims to explore recent advances in 'omics' technology and big data analysis. The focus will be on how to tackle highly complex questions such as why some individuals become obese and others don't. The problem will be presented from a range of societal, biological and evolutionary perspectives to increase breadth of knowledge on the problem of obesity. You will be provided a research training opportunity to contribute to our understanding of the relevant problems of over-nutrition in our society. Collaborative research is supported by lectures and tutorials on nutrition science, systems thinking and data coding and analysis to deepen data literacy and enhance interdisciplinary communication and collaboration.
Senior elective units of study
BCHM3071 Molecular Biology and Biochemistry-Genes

Credit points: 6 Teacher/Coordinator: Dr Giselle Yeo Session: Semester 1 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3971 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester practical work and assignments (30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study is designed to provide a comprehensive coverage of the activity of genes in living organisms, with a focus on eukaryotic and particularly human systems. The lecture component covers the arrangement and structure of genes, how genes are expressed, promoter activity and enhancer action. This leads into discussions on the biochemical basis of differentiation of eukaryotic cells, the molecular basis of imprinting, epigenetics, and the role of RNA in gene expression. Additionally, the course discusses the effects of damage to the genome and mechanisms of DNA repair. The modern techniques for manipulating and analysing macromolecules such as DNA and proteins and their relevance to medical and biotechnological applications are discussed. Techniques such as the generation of gene knockout and transgenic mice are discussed as well as genomic methods of analysing gene expression patterns. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of genes within the human genome. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology laboratories.
Textbooks
Lewin, B. Genes XI. 11th edition. Jones and Bartlett. 2014.
BCHM3971 Molecular Biology and Biochem-Genes (Adv)

Credit points: 6 Teacher/Coordinator: Dr Giselle Yeo Session: Semester 1 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3071 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study is designed to provide a comprehensive coverage of the activity of genes in living organisms, with a focus on eukaryotic and particularly human systems. The lecture component covers the arrangement and structure of genes, how genes are expressed, promoter activity and enhancer action. This leads into discussions on the biochemical basis of differentiation of eukaryotic cells, the molecular basis of imprinting, epigenetics, and the role of RNA in gene expression. Additionally, the course discusses the effects of damage to the genome and mechanisms of DNA repair. The modern techniques for manipulating and analysing macromolecules such as DNA and proteins and their relevance to medical and biotechnological applications are discussed. Techniques such as the generation of gene knockout and transgenic mice are discussed as well as genomic methods of analysing gene expression patterns. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of genes within the human genome. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology laboratories.
The lecture component of this unit of study is the same as BCHM3071. Qualified students will attend seminars/practical classes in which more sophisticated topics in gene expression and manipulation will be covered.
Textbooks
Lewin, B. Genes XI. 11th edition. Jones and Bartlett. 2014.
BCHM3081 Mol Biology and Biochemistry-Proteins

Credit points: 6 Teacher/Coordinator: Prof Jacqui Matthews Session: Semester 1 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3981 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study is designed to provide a comprehensive coverage of the functions of proteins in living organisms, with a focus on eukaryotic and particularly human systems. Its lecture component deals with how proteins adopt their biologically active forms, including discussions of protein structure, protein folding and how recombinant DNA technology can be used to design novel proteins with potential medical or biotechnology applications. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of proteins. It also covers physiologically and medically important aspects of proteins in living systems, including the roles of chaperones in protein folding inside cells, the pathological consequences of misfolding of proteins, how proteins are sorted to different cellular compartments and how the biological activities of proteins can be controlled by regulated protein degradation. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology and protein biochemistry laboratories.
Textbooks
Williamson M. How Proteins Work. Garland. 2012.
BCHM3981 Mol Biology and Biochem-Proteins (Adv)

Credit points: 6 Teacher/Coordinator: Prof Jacqui Matthews Session: Semester 1 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3081 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study is designed to provide a comprehensive coverage of the functions of proteins in living organisms, with a focus on eukaryotic and particularly human systems. Its lecture component deals with how proteins adopt their biologically active forms, including discussions of protein structure, protein folding and how recombinant DNA technology can be used to design novel proteins with potential medical or biotechnology applications. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of proteins. It also covers physiologically and medically important aspects of proteins in living systems, including the roles of chaperones in protein folding inside cells, the pathological consequences of misfolding of proteins, how proteins are sorted to different cellular compartments and how the biological activities of proteins can be controlled by regulated protein degradation. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology and protein biochemistry laboratories.
The lecture component of this unit of study is the same as BCHM3081. Qualified students will attend seminars/practical classes in which more sophisticated topics in protein biochemistry will be covered.
Textbooks
Williamson M. How Proteins Work. Garland. 2012.
BCHM3072 Human Molecular Cell Biology

Credit points: 6 Teacher/Coordinator: Dr Markus Hofer Session: Semester 2 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3972 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study will explore the responses of cells to changes in their environment in both health and disease. The lecture course consists of four integrated modules. The first will provide an overview of the role of signalling mechanisms in the control of human cell biology and then focus on cell surface receptors and the downstream signal transduction events that they initiate. The second will examine how cells detect and respond to pathogenic molecular patterns displayed by infectious agents and injured cells by discussing the roles of relevant cell surface receptors, cytokines and signal transduction pathways. The third and fourth will focus on the life, death and differentiation of human cells in response to intra-cellular and extra-cellular signals by discussing the eukaryotic cell cycle under normal and pathological circumstances and programmed cell death in response to abnormal extra-cellular and intra-cellular signals. In all modules emphasis will be placed on the molecular processes involved in human cell biology, how modern molecular and cell biology methods have led to our current understanding of them and the implications of them for pathologies such as cancer. The practical component is designed to complement the lecture course, providing students with experience in a wide range of techniques used in modern molecular cell biology.
Textbooks
Alberts, B. et al. Molecular Biology of the Cell. 6th edition. Garland Science. 2014.
BCHM3972 Human Molecular Cell Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Markus Hofer Session: Semester 2 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3072 Assessment: One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study will explore the responses of cells to changes in their environment in both health and disease. The lecture course consists of four integrated modules. The first will provide an overview of the role of signalling mechanisms in the control of human cell biology and then focus on cell surface receptors and the downstream signal transduction events that they initiate. The second will examine how cells detect and respond to pathogenic molecular patterns displayed by infectious agents and injured cells by discussing the roles of relevant cell surface receptors, cytokines and signal transduction pathways. The third and fourth will focus on the life, death and differentiation of human cells in response to intra-cellular and extra-cellular signals by discussing the eukaryotic cell cycle under normal and pathological circumstances and programmed cell death in response to abnormal extra-cellular and intra-cellular signals. In all modules emphasis will be placed on the molecular processes involved in human cell biology, how modern molecular and cell biology methods have led to our current understanding of them and the implications of them for pathologies such as cancer. The practical component is designed to complement the lecture course, providing students with experience in a wide range of techniques used in modern molecular cell biology.
The lecture component of this unit of study is the same as BCHM3072. Qualified students will attend seminars/practical classes in which more sophisticated topics in modern molecular cell biology will be covered.
Textbooks
Alberts, B. et al. Molecular Biology of the Cell. 6th edition. Garland Science. 2014.
BCHM3082 Medical and Metabolic Biochemistry

Credit points: 6 Teacher/Coordinator: A/Prof Gareth Denyer Session: Semester 2 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3982 Assessment: One 2.5-hour exam (theory and theory of prac 65%), in-semester (practical work and assignments 35%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.
This unit of study will explore the biochemical processes involved in the operation of cells and how they are integrated in tissues and in the whole human body in normal and diseased states. These concepts will be illustrated by considering whole-body aspects of energy utilisation, fat and glycogen storage and their regulation under normal conditions compared to obesity and diabetes. Key concepts that will be discussed include energy balance, regulation of metabolic rate, control of food intake, tissue interactions in fuel selection, the role of adipose tissue and transport of fuel molecules from storage organs and into cells. Particular emphasis will be placed on how the modern concepts of metabolomics, coupled with molecular biology methods and studies of the structure and function of enzymes, have led to our current understanding of how metabolic processes are normally integrated and how they become deranged in disease states. The practical component is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in modern medical and metabolic biochemistry.
BCHM3982 Medical and Metabolic Biochemistry (Adv)

Credit points: 6 Teacher/Coordinator: A/Prof Gareth Denyer Session: Semester 2 Classes: Two 1-hour lectures per week; two 3-hours practicals per fortnight Prerequisites: [An average mark of 75 in 12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and a mark of 75 or above in BMED2405 and a mark of 75 or above in 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)] Prohibitions: BCHM3082 Assessment: One 2.5-hour exam (theory and theory of prac 65%), in-semester (practical work and assignments 35%) Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
This unit of study will explore the biochemical processes involved in the operation of cells and how they are integrated in tissues and in the whole human body in normal and diseased states. These concepts will be illustrated by considering whole-body aspects of energy utilisation, fat and glycogen storage and their regulation under normal conditions compared to obesity and diabetes. Key concepts that will be discussed include energy balance, regulation of metabolic rate, control of food intake, tissue interactions in fuel selection, the role of adipose tissue and transport of fuel molecules from storage organs and into cells. Particular emphasis will be placed on how the modern concepts of metabolomics, coupled with new methods, including magnetic resonance techniques and molecular biology methods, as well as studies of the structure and function of enzymes, have led to our current understanding of how metabolic processes are normally integrated and how they become deranged in disease states. The practical component is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in modern medical and metabolic biochemistry. Qualified students will attend some lectures/practical classes in common with BCHM3082 and some separate lectures/ practical classes in which more sophisticated topics in metabolic biochemistry will be covered.
PHSI3009 Frontiers in Cellular Physiology

Credit points: 6 Teacher/Coordinator: Prof David Cook Session: Semester 1 Classes: 2 x 1 hr/ week lectures and 6 x 2 hr large class tutorials (CBL) per semester Prerequisites: (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [BMED2401 and an additional 12cp from (BMED2402 or BMED2403 or BMED2405 or BMED2406)] Prohibitions: PHSI3905 or PHSI3906 or PHSI3005 or PHSI3006 or PHSI3909 Assessment: one mid-semester exam (MCQ), one 2 hr final exam (MCQ), two presentations for challenge-based learning and 1 practical class report Practical field work: 3 x 2-4 hr practicals per semester Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: We strongly recommend that students take both (PHSI3009 or PHSI3909) and (PHSI3010 or PHSI3910) units of study concurrently
The aim of this unit is to provide students with advanced knowledge of cellular physiology. There will be a detailed exploration of the signals and pathways cells use to detect and respond to environmental changes and cues. Important signalling systems and homeostatic regulators will be discussed in the context of biological processes and human diseases. Challenge-based learning sessions will explore these diseases with student-led teaching. Practical classes will explore physiological techniques for investigating cell signalling and the biophysical properties of cells. Large class tutorials will focus on graduate attribute skills development in the context of reinforcing material discussed in the lectures and practical classes. This unit will develop key attributes that are essential for a science graduate as they move forward in their careers.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science
PHSI3909 Frontiers in Cellular Physiology (Adv)

Credit points: 6 Teacher/Coordinator: Prof David Cook Session: Semester 1 Classes: 2 x 1hr/ week lectures and 3 x 2 hrs large class tutorials (CBL) per semester Prerequisites: A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BMED2402 or BMED2403 or BMED2406)]} Prohibitions: PHSI3009 or PHSI3005 or PHSI3905 or PHSI3006 or PHSI3906 Assessment: one mid-semester exam (MCQ), one 2hr final exam (MCQ), one presentation for challenge-based learning and one Advanced research report Practical field work: 3 x 2-4 hr practicals per semester Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The aim of this unit is to provide students with advanced knowledge of cellular physiology. There will be a detailed exploration of the signals and pathways cells use to detect and respond to environmental changes and cues. Important signalling systems and homeostatic regulators will be discussed in the context of biological processes and human diseases. Challenge-based learning sessions will explore these diseases with student-led teaching. Practical classes will explore physiological techiques for investigating cell signalling and biophysical properties of cells. Large class tutorials will focus on graduate attribute skills development in the context of reinforcing material discussed in the lectures and practical classes. This unit will develop key attributes that are essential for science a graduate as they move forward in their careers.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science
PHSI3010 Reproduction, Development and Disease

Credit points: 6 Teacher/Coordinator: Stephen Assinder Session: Semester 1 Classes: 2 x 1hr lectures per week; 1 guest lecture/problem-based learning class introduction/organisation session per week. 2 x 3 hour problem-based learning classes per semester. Prerequisites: (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BCMB2X02 or BIOL2X29 or GEGE2X01)] or [12cp from (BMED2402 or BMED2403 or BMED2406)] Prohibitions: PHSI3905 or PHSI3906 or PHSI3005 or PHSI3006 or PHSI3910 Assessment: one mid-semester MCQ exam, one 2hr final exam, two problem-solving learning tutorials, 3 practical class reports Practical field work: 3 x 3 hr practicals per semester Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The aim of this unit is to provide students with advanced knowledge of the physiological processes that regulate normal and how these may go awry leading to significant human conditions or even disease. Lectures will focus on; male and female reproductive physiology, endocrinology of reproduction, physiology of fertilisation, cell cycle control and apoptosis, mechanisms of differentiation, gastrulation, cardiovascular development, tissue formation and organogenesis, stem cell biology and the link between developmental processes and cancer. Problem-based learning will focus on reproductive physiology and re-activation of developmental processes in adult disease. Practical classes will examine the processes regulating reproductive physiology, sexual dimorphism and human pathophysiology.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science
PHSI3910 Reproduction, Development and Disease Adv

Credit points: 6 Teacher/Coordinator: Stephen Assinder Session: Semester 1 Classes: 2 x 1hr lectures per week; 1 guest lecture/problem-based learning class introduction/organisation session per week; 2 x 3 hour stem cell laboratory presentations per semester. Prerequisites: A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or [12cp from (BCMB2X02 or BIOL2X29 or GEGE2X01)] or [12cp from (BMED2402 or BMED2403 or BMED2406)]} Prohibitions: PHSI3010 or PHSI3005 or PHSI3905 or PHSI3006 or PHSI3906 Assessment: one mid-semester MCQ exam, one 2hr final exam,stem cell labortory class (2 presentations), 3 practical class reports Practical field work: 4 x 4 hr practicals per semester Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The aim of this unit is to provide students with advanced knowledge of the physiological processes that regulate normal and how these may go awry leading to significant human conditions or even disease. Lectures will focus on; male and female reproductive physiology, endocrinology of reproduction, physiology of fertilisation, cell cycle control and apoptosis, mechanisms of differentiation, gastrulation, cardiovascular development, tissue formation and organogenesis, stem cell biology and the link between developmental processes and cancer. Practical classes will examine the processes regulating reproductive physiology, sexual dimorphism and human pathophysiology. Students enrolling in PHSI3910 complete a separate laboratory class centered on stem cell differentiation to replace the problem-based learning exercises in PHSI3010.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science
PHSI3012 Physiology of Disease

Credit points: 6 Teacher/Coordinator: A/Prof Matthew Naylor Session: Semester 2 Classes: 2 x 1hr lectures, 12 x 1hr tutorials, 1 x 6hr practical Prerequisites: (PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or 12cp from (BMED2402 or BMED2403 or BMED2404 or BMED2406) Prohibitions: PHSI3007 or PHSI3008 or PHSI3907 or PHSI3908 or PHSI3912 Assessment: one mid-semester MCQ exam, one 2hr final exam, two problem-solving learning tutorials, 2 practical class reports Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The aim of this unit is to provide students with advanced knowledge of whole body physiology. Lectures will provide insight into the mechanisms that regulate normal homeostasis throughout the whole body and how defects in these processes can lead to significant human disease. The emphasis in this unit is on recent advances at the frontiers of human physiology. The processes leading to cancer, cardiovascular and metabolic disease will be explored at the molecular, cellular and whole body level. Problem-based learning will focus on cancer and cardiovascular disease and practical classes will utilise both wet lab and online resources to dissect the processes by which normal physiological processes become aberrant leading to human disease.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science
PHSI3912 Physiology of Disease (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Matthew Naylor Session: Semester 2 Classes: 2 x 1hr lectures, 1 x 6hr practical, advanced project attendance. Prerequisites: A mark of 70 or above in {(PHSI2X05 and PHSI2X06) or [(PHSI2X07 or MEDS2001) and PHSI2X08] or 12cp from (BMED2402 or BMED2403 or BMED2404 or BMED2406) Prohibitions: PHSI3012 or PHSI3007 or PHSI3907 or PHSI3008 or PHSI3908 Assessment: one mid-semester MCQ exam, one 2hr final exam, Advanced project report Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
The aim of this unit is to provide students with advanced knowledge of whole body physiology. Lectures will provide insight into the mechanisms that regulate normal homeostasis throughout the whole body and how defects in these processes can lead to significant human disease. The emphasis in this unit is on recent advances at the frontiers of human physiology. The processes leading to cancer, cardiovascular and metabolic disease will be the specific will be explored at the molecular, cellular and whole body level. Students will undertake an Advanced Project Problem-based learning will focus on cancer and cardiovascular disease and Practical classes will utilise both wet lab and online resources to dissect the processes by which normal physiological processes become aberrant leading to human disease.
Textbooks
Alberts, B. Molecular Biology of the Cell. 5th edition. Garland Science