Oral Pathology Research Unit

Lab head: Munira Xaymardan
Location: Oral Pathology Unit, Westmead Hospital, Westmead, NSW 2145

Funding: University Internal Funding

Role of Platelet Derived Growth factor Receptor Alpha cells in Tooth Development

Primary supervisor: Munira Xaymardan

An opportunity exists for an Honor’s student to study the role of Platelet Derived Growth Factor Receptor (PDGFRa) cells during tooth development. The study will be a collaborative work with Profession Patrick Tam at Children’s Research Institute. PDGFRa is derived from neural crest and expressed in odontoblasts, ameloblasts of developing tooth, and mesenchymal cells of adult dental pulp. Characterisation of PDGFRa cells during embryonic development would help identify determinant factors that drive the cells towards dental fate, which may help to harness adult stem cells/progenitor cells into desired cell types that can be used for tissue repair. Genetic mouse models including conditional knockout mouse models will be used in this study.

Scholarship available

Contact Dr. Munira Xayamardan

Email: Munira.xaymardan@usyd.edu.au; Phone 02 9351 8324; Mobile 0404345236

Discipline: Pathology
Co-supervisors: Patrick Tam, Neil Hunter, Hans Zoellner
Keywords: Stem cell biology, Dentistry, PDGF