Skin Inflammation Group

Lab head: Ben Roediger
Location: Centenary Institute

Functional heterogeneity of group 1 innate lymphoid cells

Primary supervisor: Ben Roediger

The liver is home to large numbers of T cells, NK cells and group 1 innate lymphoid cells (ILC1). ILC1  are the most recently described immune cell in the body and as such are the most poorly understood. Although the developmental pathway regulating ILC1 development are becoming better known. the function of these cells, particularly in the liver, remains unclear. We have observed that ILC1 are highly diverse, and comprise many subsets. It remains unclear whether these subsets are functionally distinct. This project will employ flow cytometry and fluorescent imaging together with in vitro and in vivo models to elucidate the functional diversity of liver ILC1.

Discipline: Infectious diseases and Immunology
Co-supervisors: Patrick Bertolino
Keywords: Animal Models, Innate Immunity, Immunology