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GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

The primary cilia in diabetic kidney disease: targeting the cellular antennas

This project explores the role of the kidney proximal tubule cell primary cilia in diabetic nephropathy. Diabetic kidney disease is a leading cause of end stage kidney disease, requ more...

Supervisor(s): Panchapakesan, Usha (Associate Professor)

PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)

Investigating disease in threatened Australian wildlife

This PhD project aims to investigate disease in threatened Australian wildlife using conservation immunogenetics, and forms part of an ARC Discovery project entitled “Marsupia more...

Supervisor(s): Belov, Katherine (Kathy) (Professor)

Genomics of deafness in the Dalmatian and Australian Cattle Dog

Dalmatian and Australian Cattle Dog breeds are at increased risk of deafness compared with other dog breeds in Australia. Our project explores the links between deafness, coat colou more...

Supervisor(s): Wade, Claire (Professor)

Creating new synthetic biology tools for genome engineering in bacteria

The new discipline of synthetic biology (SynBio) promises to transform every aspect of our lives, from medicines to agriculture to industry. The vision of SynBio is that organisms c more...

Supervisor(s): Coleman, Nicholas (Associate Professor)

Investigating the genetic impacts of Tasmanian devil translocations

This PhD project aims to investigate the genetic impacts of Tasmanian devil translocations, and forms part of an ARC Linkage project “Will genetic rescue save the devil?&rdquo more...

Supervisor(s): Belov, Katherine (Kathy) (Professor)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

Chronic Hepatitis B: from virological concepts to cure

We are seeking passionate Ph.D. and Masters candidates to conduct a research project on understanding how hepatitis B virus persists in the liver to ultimately design a cure for chr more...

Supervisor(s): Tu, Thomas (Dr), Douglas, Mark W (Associate Professor)

Clonal events leading up to cancer initiation

We are seeking passionate Ph.D. and Masters candidates to conduct a research project on the cellular evolution of pre-cancerous tissue to tumour formation. We particularly encourage more...

Supervisor(s): Tu, Thomas (Dr), George, Jacob (Professor)