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Genetics of Healthy Ageing

By exploiting the vast genetic landscape of an outbred mouse population we aim to explore the molecular cause of a range of diseases that limit healthy ageing in humans. This includ more...

Supervisor(s): James, David (Professor)

Targeting Rab7 and TBC1D15 to overcome mitochondrial dysfunction in neurological diseases

Pharmacological manipulation of contacts between mitochondria and LE/Lys could provide opportunities to improve PD, CMT2B and NPC disease. Virtual screening of compound libraries wi more...

Supervisor(s): Grewal , Thomas (Associate Professor), Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

MODELLING EFFECTS OF LIGHT ON THE CIRCADIAN RHYTHMS

This project aims to advance our understanding of the effects of light on the circadian rhythms and develop a detailed biophysical model of the circadian photoreceptor system that i more...

Supervisor(s): Postnova, Svetlana (Dr)

The Physics of Circadian Desynchrony

This project will investigate brain mechanisms and health consequences of circadian misalignment. more...

Supervisor(s): Postnova, Svetlana (Dr)

QUANTIFYING INTER-INDIVIDUAL VARIABILITY IN CIRCADIAN RHYTHMS

The overarching goal of this set of projects is to understand the brain mechanisms of inter-individual variability in circadian rhythms and develop tools for personalized prediction more...

Supervisor(s): Postnova, Svetlana (Dr)

Clinical outcomes analysis of patients who undergo resection of neuroendocrine liver metastases

The Upper GI surgery department at RNSH is a tertiary referral unit which has treated many patients with neuroendocrine tumours over the past 20 years. RNSH is recognized as a NSW c more...

Supervisor(s): Hugh, Thomas J (Professor)

3D versus 2D visualisation in laparoscopic surgery – is their a clinically significant difference?

The benefits of using a 3D visualisation camera system while performing laparoscopic surgery will be assessed using an objective scoring tool of operative skills. The aim of th more...

Supervisor(s): Hugh, Thomas J (Professor)

Dissecting the architecture of the Insulin Signaling Pathway

The aim of this pathway is to understand how the insulin signalling pathway regulates metabolic homeostasis.The Lead Supervisor for this project is David James. This project will a more...

Supervisor(s): James, David (Professor)