Research Supervisor Connect
We are looking for an enthusiastic PhD candidate to lead a series of studies alongside a passionate group of clinicians and researchers within the Cardio-Sleep research program at the Charles Perkins Centre, The University of Sydney. The primary focus of the candidature is to pilot the design and delivery of a randomized control trial to evaluate the effectiveness of optimised and personalised OSA therapy in patients with acute coronary syndrome for further prevention of cardiovascular diseases. The research will incorporate an interdisciplinary team collaborating across academia, clinical and international settings to better understand and treat sleep-disordered breathing in acute coronary syndrome.
Camperdown - Charles Perkins Centre
Sleep-disordered breathing, such as obstructive sleep apnoea (OSA), is emerging as an important “silent” risk factor in acute coronary syndrome. OSA is one of the most common non-communicable chronic diseases, with an estimated global prevalence of 1 billion people. There is strong epidemiological evidence of an association between OSA and acute coronary syndrome with a prevalence estimate of up to 80%.
Observational studies have shown that OSA therapy reduces the risk of developing coronary events. However, the direct mechanisms by which effective personalised OSA therapy minimises this risk is not clear and a causal role of OSA in the development and progression of acute coronary syndrome remains to be defined.
This project brings together state of the art technology and a multidisciplinary team of world-renowned researchers across cardiology, respiratory and sleep medicine to assess the impact of personalised OSA therapy in acute coronary syndrome for future cardiovascular disease prevention.
The candidature will also include opportunities to contribute to the broader CardioSleep research program which aims to enhance local and international partnerships through impactful research and generate improved health outcomes for our community and optimal health care delivery. The project will build on existing capabilities and collaborations, including the Sydney Sleep Biobank, and will enhance research capacity through interdisciplinary research training and consumer engagement.
The opportunity ID for this research opportunity is 3324