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Dopamine dysfunction in neurological disorders

Summary

Our lab focuses of dopamine functions in learning, motivation and movement and how dopamine dysfunction impacts alcohol use disorder, Parkinson's disease and Schizophrenia.

 

 

Alcohol Use Disorder

We have published both pre-clinical studies and human postmortem brain tissues on the changes induced by alcohol use and the brain circuits that regulate relapse to alcohol seeking. 

PhD project: Dopamine alterations in the cortex in human brain in AUD 

PhD project: Inflammation targets for the treatment of AUD

 

Supervisor

Dr Asheeta Prasad.

Research location

Camperdown - Charles Perkins Centre

Synopsis

Schizophrenia

Schizophrenia is a complex neurological disorder with alternations in dopamine functions leading to the positive and negative symptom 

PhD project available Schizophrenia: Examines cellular changes in human brain in Schizophrenia postmortem human brains that regulate dopamine functions.

 

Parkinson's disease

Dopamine loss is a hallmark of Parkinson's disease pathology which contributes to motor dysfunction and also non-motor symptoms of depression, pain and cognition.  

PhD project: Neurobiological mechanism of deep brain stimulation in Parkinson's disease 

PhD project: available: Non-motor symptoms of Parkinson's diseases

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Opportunity ID

The opportunity ID for this research opportunity is 3602