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Functional Genomics, Genetics and Bioinformatics of Cereal Rust Fungi

De Novo genome assembly using third generation sequencing RNA-seq based genomic annotation for cereal rust fungi Comparative genomics of cereal robust isolates in pursuit of avi more...

Supervisor(s): Wu, Jingqin (Dr)

Viral Commandeering of Cellular Oncogenic Signalling Pathways

Cell-to-cell spread of caccinia virus infection induces dramatic rearrangements to cell morphology and alterations to cell behaviour.  This project will study the role of host more...

Supervisor(s): Newsome, Timothy (Dr)

Computational approaches to elucidate Multiple Sclerosis and Contact Dermatitis pathogenesis, and its treatment through ultraviolet light exposure

Allergies and autoimmunity are complex immune system aberrations. Both involve multiple immune cell populations coordinating across several organs of the body. The growing prevalenc more...

Supervisor(s): Read, Mark (Dr)

Regulation of stem cell behaviour using functional biomolecules

Investigate and develop new ways of manipulating different aspects of stem cell behaviour.  This knowledge paves the way towards understanding their fundamental biology and cre more...

Supervisor(s): Yeo, Giselle (Dr)

Improving the Health of Urbanised Estuaries

Degraded estuaries, such as those in close proximity to urbanization, have a limited capacity to process contaminants as they have lost animals key to improving sediment and water q more...

Supervisor(s): Bugnot, Ana (Dr)

Characterising changes in a proteome of islets and islet cell types during progression to type 2 diabetes

Characterizing changes in a proteome through pathogenesis of diseases can provide unparalleled insights into the mechanisms underpinning disease. In this project, using flow cytomet more...

Supervisor(s): Kebede, Melkam (Dr)

Characterising insulin secretory granules as a function of age

In β-cells, insulin is stored in secretory granules (SGs). Upon stimulation, these SGs deliver insulin to the bloodstream. It is known that SGs exist in two functionally distin more...

Supervisor(s): Kebede, Melkam (Dr)

Sorting proinsulin into secretory vesicles

Reduction in glucose-stimulated mature insulin secretion and increased constitutive and regulated secretion of proinsulin are characteristics of β-cell failure. This may be due more...

Supervisor(s): Kebede, Melkam (Dr)

Mechanisms of Transgenerational Epigenetic inheritance

We are interested in understanding the molecular mechanisms that allow a phenomenon called epigenetic inheritance to occur: that is, the transmission of non-genetic information from more...

Supervisor(s): Ashe, Alyson (Dr)

Tracking antibiotic resistance genes and mobile genetic elements in the environment

Antibiotic resistance is a massive problem for medicine, and thus much effort is being put into understanding the genetic basis of how bacteria evolve so quickly to become resistant more...

Supervisor(s): Coleman, Nicholas (Associate Professor)