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Structure-based drug design with Kynurenine Aminotransferase-2

Human kynurenine amino transferase-2 (KAT-2) forms the basis of a structure-based drug design study with implications for schizophrenia and gender differences.  The various asp more...

Supervisor(s): Church, W Bret (Dr)

Display of Viral Surface Glycoprotein on Virus like particles (VPLS) for Structure and Immune Epitope Discovery

Unanchored recombinant soluble monomers are often the proteins used in many structure analyses and immunologic testing. But in reality viral surface glycoproteins are orientated, te more...

Supervisor(s): Lynch, Garry (Dr)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

Investigating disease in threatened Australian wildlife

This PhD project aims to investigate disease in threatened Australian wildlife using conservation immunogenetics, and forms part of an ARC Discovery project entitled “Marsupia more...

Supervisor(s): Belov, Katherine (Kathy) (Professor)

Fibre-based Scaffolds for Neural Implants

The project will focus on design and fabrication of biodegradable and biocompatible micro-structured fibres based on our current breakthrough in fabrication of fibres in low Young&r more...

Supervisor(s): Rukhlenko, Ivan (Dr), Fleming, Simon (Professor), Farajikhah, Syamak (Dr)

Molecular insights into a novel mammalian oxygen-sensing pathway

Oxygen (O2) is a vital biological resource most prominently known for its role as the final electron acceptor in aerobic respiration and, as such, adequate molecular mechanisms are more...

Supervisor(s): White, Mark (Dr), Mackay, Joel (Professor)

Novel THz waveguides

The THz spectrum is of great technological and scientific interest. However it is challenging because of the extremely limited range of components. This project will develop compone more...

Supervisor(s): Fleming, Simon (Professor)

Metamaterial Hyperlenses for THz Sub-diffraction Imaging

Metamaterials are an exciting new class of artificial materials that can have extraordinary properties functionality. We have demonstrated a novel technique to make them and hav more...

Supervisor(s): Fleming, Simon (Professor)

Poling multilayer dielectric structures for compact active optical devices

Optical communications technology has transformed the world. There is a need to get more optical processing functionality into smaller devices, for applications ranging from inexpen more...

Supervisor(s): Fleming, Simon (Professor)

STUDIES OF VARIABLE OR CONSERVED SURFACE PROTEIN SITES OF NEISSERIA MENINGITIDIS AS EPITOPES FOR STRAIN-SPECIFIC VACCINES OR BROAD-STRAIN (UNIVERSAL) VACCINES

The gram-negative Neisseria Meningititis (NM) remains a significant microbial problem and particularly lethal for the very young. Serogroup B strains are particularly troublesome an more...

Supervisor(s): Lynch, Garry (Dr)