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PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)

Studies in Cell-Projection Pumping

Cell-projection pumping (CPP) is a mechanism we have recently discovered whereby cells pump cytoplasm between each other. We have discovered this in context of cancer, where there i more...

Supervisor(s): Zoellner, Hans (Professor)

Green Chemistry - Biocatalysis For Production Of High-Value Chemicals

The ultimate aim of biocatalysis research is to replace the petrochemical industry with clean and green microbial reactions using renewable and non-toxic feedstocks. But how exactly more...

Supervisor(s): Coleman, Nicholas (Associate Professor), Rutledge, Peter (Professor)

Structure-based drug design with Kynurenine Aminotransferase-2

Human kynurenine amino transferase-2 (KAT-2) forms the basis of a structure-based drug design study with implications for schizophrenia and gender differences.  The various asp more...

Supervisor(s): Church, W Bret (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)

Organometallics and Catalysis

The projects will focus on novel monometallic and multimetallic transition metal catalysts as well as new methodologies for catalysis and developing surface supported catalysts. The more...

Supervisor(s): Messerle, Barbara (Professor)

Social Policy Research Network

We bring together researchers and practitioners from within the University of Sydney and from non-profit and public sectors. We help coordinate research collaborations, host more...

Supervisor(s): Ravulo, Jioji (Professor), Goodwin, Susan (Professor), Heward-Belle, Susan (Dr), Phillips, Ruth (Associate Professor), Rawsthorne, Margot (Associate Professor), Spencer, Margaret (Dr), Tseris, Emma (Dr)

Modelling plasma synthesis of nanoparticles for non-invasive diagnosis and targeted treatment of disease

This project will develop multiphysics models of a low temperature capacitively coupled plasma reactor to engineer functionalised nanoparticles for biomedical applications.This proj more...

Supervisor(s): Bilek, Marcela (Professor), Baldry, Mark (Dr)

Cardiovascular diseases in old and frail people

We welcome PhD and Master Students to contribute to some of our ongoing projects or to develop their own proposals, within the theme of geriatric cardiology and cardiovascular pharm more...

Supervisor(s): Nguyen, Tu (Dr)

Develop point-of-care microfluidic technologies for cardiovascular and cerebrovascular diseases

We are developing a clinically useful, rapid and high throughput profiling microdevices for thrombosis and coagulation. It will be extremely useful for patients with diabetes, obesi more...

Supervisor(s): Ju, Lining (Arnold) (Dr)