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Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

Microglia are the immune cells of the brain and are known to respond to infectious and non-infectious insults to the nervous system. Recently, a new function has been demonstrated f more...

Supervisor(s): Graeber, Manuel (Professor), Becker , Thomas (Professor)

Targeting abnormal immune function in the central nervous system to treat cognitive disorders.

There is a growing body of evidence that most neurocognitive disorders, neurodegenerative diseases, and neuropathic pain states involve abnormal immune activity within the central n more...

Supervisor(s): Johnston, Ian (Dr)

Search for a cause: the role of astrocytes in the early pathology of Parkinson's disease

The projects in our lab are directed towards finding the cause of Parkinson’s Disease.  In particular we want to know what is the nature of the mechanism that sets the ne more...

Supervisor(s): Allbutt, Haydn (Dr)

Embryonic stem cells

Embryonic stem (ES) cells have the potential to differentiate into any cell type of the developing embryo and adult. For this reason they have proved invaluable in understanding the more...

Supervisor(s): Morris, Michael (Dr)

Elucidating the neural mechanisms of stress: a 13C-NMR study of glutamate and neuronal-glial interactions

13C-Magnetic Resonance Spectroscopy (13C-MRS) is an emerging imaging modality that allows the measurement of concentrations and synthesis rates of glutamate, glutamine and GABA with more...

Supervisor(s): Lagopoulos, Jim (Associate Professor)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)