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Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

The molecular basis of persistence in clinical P. aeruginosa strains from cystic fibrosis patients

Pseudomonas aeruginosa, the leading cause of morbidity and mortality in people with cystic fibrosis (CF), adapts to survive in the CF lung through both mutation and gene expression more...

Supervisor(s): Manos, Jim (Dr), Triccas, Jamie (Dr)

Investigation of virulence genes upregulated in coinfection between P. aeruginosa and other species

Identify the set of genes diffrentially expressed when P. aeruginosa is grown in coculture with three other infecting species. Select genes with virulence/persistence characteristic more...

Supervisor(s): Manos, Jim (Dr)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of New Anti-Bacterial Agents

This project would appeal to those with interests in pharmaceutical applications of medicinal and protein chemistry. more...

Supervisor(s): Groundwater, Paul (Professor), Church, W Bret (Dr), Hibbs, David (Dai) (Professor)