Jenny Zhenqi Zhang
room 412b
School of Chemistry, Building F11,
University of Sydney, NSW, Australia
ph: +61 2 9351 8741
j.zhang@chem.usyd.edu.au
Highlights
Currently working towards a PhD in Chemistry, School of Chemistry, The University of Sydney.
Supervisor: Professor Trevor Hambley.
Project title: Platinum-anthraquinone complexes as anti-tumour agents.
Research emphasis: To synthesise and compile a library of platinum-anthraquinone complexes with different tumour penetration enhancing properties, and testing them in cells and tumour spheroid models.
Presented an oral presentation at the Asian Biological Inorganic Chemistry Conference, 2009, in Jeju Island, Korea on ‘Platinum-Anthraquinone Complexes and their Uptake in Cancer Cells and Solid Tumour Models’
Organised the student symposium ‘Discussions Regarding Sydney Postgraduates of Chemistry (DRSPOC)’ for the School of Chemistry, The University of Sydney, for both 2007 and 2008.
Completed a Bachelor of Science (Advanced) degree, graduating with Honours Class I.
Project Title: Lysosomal localisation of Platinum-anthraquinone complexes,
Supervisor: Trevor Hambley, School of Chemistry, The University of Sydney.
Education
2007 to present: Doctor of Philosophy (Science) candidate: Chemistry, The University of Sydney. Supervisor: Professor Trevor Hambley,.
2006: Bachelor of Science (Advanced) with Honours: Honours Class I in Chemistry, The University of Sydney. Supervisor: Professor Trevor Hambley.
Professional Experience
2007-present
Post-graduate Teaching Fellow, School of Chemistry, The University of Sydney. Duties: Conducting weekly classroom tutorials (to undergraduate students) and aiding students, developing effective tutorial activities and teaching strategies, carrying out formal assessments, grading exams.
2006-2007
Summer Research Scholarship, School of Chemistry, The University of Sydney. Supervisor: Professor Trevor Hambley. Duties: Continuing work from Honours project, aiding new students and writing papers.
2006
Laboratory Demostrator, School of Chemistry, The University of Sydney. Duties: Demonstration of laboratory techniques to undergraduate chemistry students, maintaining a safe working environment, giving tutorials, supervising experiments, marking experiments and assessments.
2005
Summer Research Scholarship, School of Chemistry, The University of Sydney. Supervisor: Professor Trevor Hambley. Project title: Synthesis of fluorescent platinum(II)-coumarine anti-cancer complexes
Publications
,
Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour model.
2009,
Chemical Communications,
Submitted
,
Investigations Using Fluorescent Ligands to Monitor Platinum(IV) Reduction and Platinum(II) Reactions in Cancer Cells.
2009,
Dalton Transactions,
Accepted
,
Fluorescent Analogues of Quinoline Reveal Amine Ligand Loss from cis and trans Platinum(II) Complexes in Cancer Cells.
2009,
Daltons Transactions,
Submitted
,
Chemical Biology of Platinum Anticancer drugs: New Approaches to an Old Problem
2008,
Wiley Encyclopedia of Chemical Biology ,
Accepted
Conferences
Asian Biological Inorganic Chemistry Conference, Jeju Island, Korea
10-13th November, 2008
Oral Presentation: Platinum-Anthraquinone Complexes and their Uptake in Cancer Cells and Solid Tumour Models
Authors: J. Z. Zhang, N. S. Bryce, T. W. Hambley
International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy, Verona, Italy.
30th November-3rd December, 2007
Poster Presentation: Platinum-anthraquinone Anticancer Complexes: Best of both worlds?
Authors: J. Z. Zhang, R. M. Whan, R. A. Alderden, T. W. Hambley
International Conference of Biological Inorganic Chemistry, Vienna, Austria.
15th-20th July, 2007
Poster Presentation: The Intracellular Interactions of Platinum-Anthraquinone Anti-cancer Complexes
Authors: J. Z. Zhang, R. M. Whan, R. A. Alderden, T. W. Hambley
Drug Design Amongst the Vines, Hunter Valley Gardens, Polkobin, Hunter Valleys, N.S.W.
3rd -7th December, 2006
Poster Presentation: Use of Fluorescent Tags to Study the Cellular Uptake and Metabolism of Platinum and Cobalt Antitumour Complexes.
Authors: J. Z. Zhang, N. Yamamoto, S. L. Danos, R. A. Alderden and T. W. Hambley
Skills
Experienced researcher in chemistry, with training in inorganic and organic synthesis; various types of analytical techniques, including fluorescence, IR, Raman, NMR, mass, and atomic absorption spectroscopy; and acquisition and interpretation of SRIXE, XANES and EXAFS data.
E Experienced researcher in biological studies, with training in monolayer cellular and multilayered spheroid subculturing techniques, subcellular fractionation, genomic and plasmid DNA extractions, light and confocal fluorescence microscopy and various enzymic assays.
Proficient user of Microsoft Office, especially in Word, Excel and Powerpoint; Chemdraw; Endnote; and several confocal microscopy imaging programs, such as Image J and Confocal Assisstant. Also experienced with writing macros to automate processes.
Other spoken languages: Cantonese (Chinese)
Awards
Agnes Campbell Prize (for excellence in the research in Organic Chemistry) (2008)
ISBIC Travel Grant, November 2007, for ISPICC expenses
University of Sydney Postgraduate Award (2007-2010)
Extracirricular Activities
Committee member of the Sydney University Students Appeals Panel (2008-2009)
Treasurer of the Sydney University Chemical Society (2008)
Secretary of the Sydney University Postgraduates of Chemistry Society (2008)
Co-president of the Sydney University Postgraduates of Chemistry Society (2007)
Referees
Professor Trevor Hambley (School of Chemistry, The University of Sydney)
Honours and Ph.D. supervisor
Telephone: (02) 93512830
Fax: (02) 93513329
Dr Lou Rendina (School of Chemistry, The University of Sydney)
Associate Ph.D. supervisor
Telephone: (02) 93514781
Fax: (02) 93513329
Professor Scott Kable (School of Chemistry, The University of Sydney)
Post-graduate Teaching Fellows Coordinator
Telephone: (02) 93512756/ 93513811
Fax: (02) 93513329
Dr Ron Clarke (School of Chemistry, The University of Sydney)
Academic President of the Sydney University Chemical Society (2008)
Telephone: (02) 9351 4406
Fax: (02) 93513329
Ms Ellie Kable (Electron Microscopes Unit, The University of Sydney)
Cell laboratory manager
Telephone: (02) 93517566
Fax: (02) 93517682