The Kassiou Research
Group
Medicinal Chemistry & Drug Discovery
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The Kassiou Research Group is on
level 5 of the School of Chemistry and level 4 of the Discipline of
Pharmacology. Through these two facilities our group has access to
state-of-the-art equipment for medicinal chemistry (including analytical
techniques such as HPLC, NMR and mass spectrometry) as well as facilities for
screening active molecules, and performing behavioural assays. |
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Synthetic Chemistry Laboratory Our synthetic chemistry
laboratory provides the facilities for the synthesis and development of novel
bioactive CNS molecules. Rational design principles are used to generate
ligands, allowing us to further explore structure-activity relationships. The laboratory provides access
to the latest technology available in modern organic synthetic chemistry,
such as variable pressure-temperature microwave reactors and photoreactors. |
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In Vitro Drug
Screening Laboratory Our in vitro drug screening laboratory is equipped with cell culture
facilities and a range of 96-well plate readers enabling the rapid evaluation
of synthesised molecular libraries against multiple identified disease
targets. |
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Behavioural Pharmacology Laboratory Our behavioural pharmacology
laboratory allows the phenotypic assessment of drug candidates in animal
models of human CNS diseases. This work is performed with our collaborator,
Professor Iain McGregor, both at the Brain and Mind Centre and the
Psychopharmacology Laboratory within the School of Psychology. |
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