Rutledge Group

• Professor Peter Rutledge, Group Lead

Research students

• Julius Adamson Redirecting Amyloid Formation Using Small-Molecule Complexes
• Mathamsanqa Bhebhe Open Source Malaria Series 3: A Promising Aminothienopyrimidine Lead
• Klementine Burrell-Sander Social Media, Science and Synthesis: Towards New Drug Candidates for the Treatment of Tuberculosis
• Hung Duong Eumycetoma: A case study in Open Source Drug Discovery and Public Engagement with Science
• Heather Lacey Hidden World: Soil-derived Actinobacteria as a Source of Pharmaceutical Leads
• Simon Marais ‘Magic Bullet’ Cancer Drugs and Antibiotics
• Carlota Rivera Montero Open-Source Tuberculosis: Synthesis and Evaluation of New Drug Candidates
• Nicholas Smith Development and Synthesis of Boron Containing Antibacterial Agents

Post-Doctoral Researchers

• Dr Malcolm Spain (2015–2017) A new class of inhibitors for the treatment of tuberculosis (NHMRC APP1084266)
• Dr Sandra Ast (2013–2015) Charting Intercellular Space (ARC DP120104035)
• Dr Qun Yu (2010–2012) Target Activated Therapeutics (NBCF Novel Concept Award)
• Dr Elizabeth Barrett (2007–2008) Biologically Inspired Catalysts for Hydrocarbon Oxidation

HDR Students

• Jamie Batten, PhD (2022) On the Antibiotic Potential of Azamacrocycles
• Nicole Chapman, PhD (2021) Ancestral Sequence Reconstruction of Isopenicillin N Synthase
• Marat Korsik, PhD (2021) Open Source Malaria: Medicinal Chemistry of Triazolopyrazines towards New Antimalarial Drug Candidates
• Paul King, PhD (2020) Synthesis of 1-Alkylisochromans: A Photoredox Strategy
• Edwin Gar-On Tse, PhD (2020) Open Source Malaria: Potent Triazolopyrazine-Based Antiplasmodium Agents that Probe an Important Mechanism of Action
• Elva Shi, MPhil (2019) Functionalised Azamacrocycles for Modulating Amyloid Aggregation
• Mojdeh Dinarvand, PhD (2018) Discovery and development of novel antibacterials from natural products
• Prarthana Devi, PhD (2016) Synthetic Approaches to a Peptide Isostere: Towards New b-Lactamase Inhibitors
• Joseph Wong, PhD (2016) Cyclam and Metal-Cyclam Complexes for Sensing and Therapeutic Applications
• Ayesha Hussain, MSc (2014) Iron Promoted Allylic Amination of Unactivated Alkenes
• Tim Sheedy, PhD (2013) Synthesis and Biological Evaluation of Chloramphenicol-Cyclam and Cholesterol-Cyclam Adducts
• Mingfeng Yu, PhD (2012) Scorpionand Metal-Cyclam Complexes Appended with Biologically-Active Motifs: Design, Synthesis and Evaluation
• Yu Heng Lau, MSc (2011) Chemical Sensors Based on Pendant Cyclam Complexes
• Kaitlin Beare, PhD (2010) Synthetic Approaches to the DEF Ring System of Integramycin
• Cillian Byrne, PhD (2008) Peptide Based Nitrile Hydration: Mimics of the Nitrile Hydratase Active Site
• Vicky Dungan, PhD (2008) Biologically Inspired Strategies for Hydrocarbon Oxidation
• Sarah Barry, PhD (2007) Non-Heme Iron Oxidase Enzymes & Enzyme Mimics in Synthesis & Biosynthesis
• Kate Houlihan, PhD (2007) Peptide Mimics of the Nitrile Hydratase Active Site
• Conor Scully, PhD (2007) A Bio-inspired Strategy for Selective Heavy Metal Detection Using Ferrocenyl Peptides

Honours Students

• Klementine Burrell-Sander (2021) Social Media, Science and Synthesis: Towards New Drug Candidates for the Treatment of Tuberculosis
• Ciara Kenneally (2021) “Exciting, empowering and engaging”- Perspectives of teachers and project leaders on citizen science in Australian classrooms
• Isaac Morgan (2020) Approaches to novel drugs to combat M. tuberculosis and other mycobacteria using target-oriented and diversity-oriented synthesis
• Natalie Mazurek (2020) The Secondary Metabolites of Bacterial Species Amycolaptosis pretoriensis
• Ben Sibary (2020) Mining Streptomyces Genomes for Bioactive Specialised Metabolites
• Lily McCubbin (2019) Diversity Oriented Synthesis as a Tool for the Development of Anti-Tubercular Compounds
• Julius Adamson (2018) Cyclam Conjugates for the Modulation of Amyloid-β Aggregation
• Maraia Pickering (2018) Design and Synthesis of Antitubercular Agents based on Amine Natural Products
• Nicholas Smith (2018) Nontoxic, Carborane-Cyclam Conjugates with Potent Anti-Tubercular Activity
• Heather Lacey (2016) The Secondary Metabolites of Novel Fungal Species Aspergillus nanangensis
• Jack Stewart (2017) The Evolutionary Origins of Non-heme Iron Oxygenases
• Sebastien Dath (2017) Investigating the Role of Target-Activated Metal Complexes within the Estrogen Receptor
• Chris Brown (2016) Target-Activated Metal Complexes for Imaging the Estrogen Receptor
• Jamie Batten (2016) Nontoxic Metal-Cyclam Complexes: Synthesis, Structure and Activity Against Mycobacterium Tuberculosis
• Ceri Jennings (2015) Towards a β-Lactamase Inhibitor
• Danial Moawad (2015) Synthesis of Novel Aromatic Substituted Di-triazoles as Potential Antituberculosis Drugs
• Hasini Murage (2015) The Synthesis of Cyclam-based compounds with Anti-tubercular activity
• Andrew Counsell (2014) Spectroscopic and Crystallographic Characterisation of Propargylic Tetraazamacrocycles
• Angus Jones (2012) Synthesis of Tetra-Click Cyclam Derivatives
• Jack Orford (2011) The Synthesis of Target-activated Metal Complexes for Breast Cancer Imaging and Therapy
• Kim Watson (2011) Cyclam Based Scorpionands: Toward a Novel Class of Antibiotics
• Daniel Hutchinson (2010) Cyclobutanone antibiotics: new drugs to combat bacterial resistance
• David Porter (2010) Allylic Aminations Using Iron Oxidation Catalysts with N-Boc-Hydroxylamine
• Teresa Nguyen (2010) Chemo-enzymatic Approaches to Epoxide-Derived Natural Products
• Samantha Cheung (2009) Biocatalytic epoxidation of alkenes using Mycobacterium sp. strain NBB4
• Yu Heng Lau (2009) Tetraazamacrocyclic Scorpionand Complexes: Synthesis and Study of Pendant Coordination
• Joseph Wong (2009) Synthetic Approaches to Cyclobutanone Analogues of β‐Lactam Antibiotics
• Belinda Poon (2008) Biomimetic Iron-based Systems for the Selective Functionalization of Hydrocarbons
• William Early (2007) Novel Peptide Mimics of the Nitrile Hydratase Active Site
• Shwo Mun Wong (2006) New Iron-Based Reagents for the Dihydroxylation of Alkenes
• Kieran Kenny (UCD, 2005) A new approach to N^d-hydroxyornithine
• Ed Larkin (UCD, 2005) Synthesis of nitrile hydratase mimics
• Eoin Rafter (UCD, 2005) New strategies for the bioremediation of nitrile contaminants
• Niall Trehey (UCD, 2005) New catalysts for hydrocarbon oxidation
• Jane Crowley (UCD, 2004) New strategies for the bioremediation of cyanide and nitriles
• Julie-Ann Lough (UCD, 2004) Design and synthesis of enzyme mimics for the oxidation of hydrocarbons: Mandelic Acid Scaffolds
• Deirdre Walsh (UCD, 2004) Design and synthesis of enzyme mimics for the oxidation of hydrocarbons: Phenylalanine Scaffolds

Summer Scholars and Visitors

• Wunna Kyaw (2017) University of Sydney Summer Scholar
• Leo Jiang (2016) University of Sydney Summer Scholar
• Jiarun (Veronica) Lin (2016) University of Sydney Summer Scholar

·       Stone Woo (2016) University of Sydney Summer Scholar

• Max Wright (2015) University of Sydney Summer Scholar
• Hazel Chan (2014) University of Sydney Summer Scholar
• Hersh Patel (2014) University College London
• Kylie Yang (2014) University of Sydney Summer Scholar
• Eve Marshall (2013) The University of York
• Emily Calandra (2013) Study Abroad Internship Program, Texas A&M University

·       Ian Wallace Moyer (2013) Study Abroad Internship Program, Rochester University

• Emma Watson (2013) University of Sydney Talented Student Program
• Andrew Counsell (2012) University of Sydney Summer Scholar
• Cyril Tang (2012) University of Sydney Talented Student Program
• Yu Heng Lau (2008) University of Sydney Talented Student Program
• Rowan Nieuwenhuizen (2008) University of Applied Science Leiden, Netherlands
• Günther Thiele (2008) Philipps Universität Marburg, Germany
• Shane Gallagher (2005) University College Dublin SFI UREKA Scholar
• Paula Williams (2005) University College Dublin SFI UREKA Scholar
• Darragh Gaffney (2004) University College Dublin SFI UREKA Scholar
• Christa Prunkl (2003) Erasmus Scholar, University of Regensburg
• Ina Rosnizeck (2003) Erasmus Scholar, University of Regensburg