Outline

Overview

The Pathogenesis of Human Disease 2 unit of study will provide a theoretical and practical background to the scientific basis of the pathogenesis of systemic diseases. Extending upon the knowledge gained from CPAT3201, areas covered in practical modules include the response of renal, cardiovascular, neurological and accessory digestive systems to disease. In the practical modules, these areas will be expanded to include specimen evaluation on a macroscopic and microscopic basis. The aims of the course are: - To provide students opportunities to understand how different organ systems react to injury through the application of basic concepts of disease processes. - To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees. At the end of the course students will: - Be able to describe, synthesise and present information on disease pathogenesis to a scientific audience. - Transfer problem-solving skills to novel situations related to disease pathogenesis. - Understand basic investigative techniques for disease detection in pathology. - Acquired practical skills in the use of a light microscope. - Evaluate diseased tissue at the macroscopic and microscopic level. Compile and maintain a detailed scientific lab notebook. This unit of study is appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquiries should be directed to melanie.white@sydney.edu.au.

Unit details and rules

Academic unit	Department of Medical Sciences
Credit points	6
Prerequisites ?	12 cp from [IMMU2X11 or IMMU2101 or MEDS2004 or MIMI2X02] or [MEDS2004 and (MEDS2001 or MEDS2003)]
Corequisites ?	None
Prohibitions ?	CPAT3902
Assumed knowledge ?	Sound knowledge of biology through meeting pre-requisites
Available to study abroad and exchange students	Yes

Teaching staff

Coordinator	Melanie White, melanie.white@sydney.edu.au
Lecturer(s)	Stuart Cordwell, stuart.cordwell@sydney.edu.au
	Melanie White, melanie.white@sydney.edu.au
	Babak Sarrafpour, babak.sarrafpour@sydney.edu.au
	Greg Sutherland, g.sutherland@sydney.edu.au

Assessment

The census date for this unit availability is 2 September 2024

Details
Criteria

Type	Description	Weight	Due	Length
Supervised exam ?	Final exam Extended answer questions covering all modules delivered	40%	Formal exam period	2 hours
Outcomes assessed:
Small continuous assessment	Submission of practical workbook EAQ with a microscopic and macroscopic evaluation of diseases	10%	Multiple weeks	One workbook per learning module
Outcomes assessed:
Participation	Museum Peer Discussions Students contribute to peer-teaching with supporting documents submitted	20%	Multiple weeks	1.5 hours and up to 500 words
Outcomes assessed:
Tutorial quiz	Quiz 1 MCQ - covering CVD and Neurological modules	10%	Week 08 Due date: 18 Sep 2024 at 13:00 Closing date: 30 Oct 2024	30 mins
Outcomes assessed:
Tutorial quiz	Quiz 2 MCQ - covering Endocrinopathies and Accessory Digestive Organ modules	10%	Week 10 Due date: 09 Oct 2024 at 13:00 Closing date: 30 Oct 2024	30 mins
Outcomes assessed:
Tutorial quiz	Quiz 3 MCQ - covering Haematopathology module and microscopic histopathology	10%	Week 13 Due date: 30 Oct 2024 at 13:00 Closing date: 23 Nov 2024	30 mins
Outcomes assessed:

Assessment summary

Practical workbooks: One workbook is available per disease module. All questions must be attempted in short answer format to be considered a completed submission. Submissions must be made before the relevant due date. No extensions or special considerations are provided.

In-class quiz: The content to be examined will include all relevant material (lectures, practicals) for CPAT3202 up until (and including) the week before the exam.

Museum Peer Discussions: Students will choose one museum specimen that best represents key pathologies across three (3) disease modules to discuss in museum tutorials to facilitate peer discussions. Submission types include PowerPoint slides and mind maps. Contributions during the timetabled museum tutorial will be peer-assessed. In alternate weeks, students will submit a mind map or decision tree to support the learning of other pathologies. No extensions or special considerations are provided.

Final Exam: The exam is comprised of extended answer questions.

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name	Mark range	Description
High distinction	85 - 100	Awarded when you demonstrate the learning outcomes for the unit at an exceptional standard.
Distinction	75 - 84	Awarded when you demonstrate the learning outcomes for the unit at a very high standard.
Credit	65 - 74	Awarded when you demonstrate the learning outcomes for the unit at a good standard.
Pass	50 - 64	Awarded when you demonstrate the learning outcomes for the unit at an acceptable standard.
Fail	0 - 49	When you don’t meet the learning outcomes of the unit to a satisfactory standard.

For more information see guide to grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

Deduction of 5% of the maximum mark for each calendar day after the due date.
After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Late assignments that have not been granted an extension will attract a penalty of 5% of the maximum mark per day late, including weekend days (e.g. if the assignment is worth 40 marks, the penalty is 2 marks per day late). Assignments submitted over 10 days late will be marked as zero (0).

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

Use of generative artificial intelligence (AI) and automated writing tools

You may only use generative AI and automated writing tools in assessment tasks if you are permitted to by your unit coordinator. If you do use these tools, you must acknowledge this in your work, either in a footnote or an acknowledgement section. The assessment instructions or unit outline will give guidance of the types of tools that are permitted and how the tools should be used.

Your final submitted work must be your own, original work. You must acknowledge any use of generative AI tools that have been used in the assessment, and any material that forms part of your submission must be appropriately referenced. For guidance on how to acknowledge the use of AI, please refer to the AI in Education Canvas site.

The unapproved use of these tools or unacknowledged use will be considered a breach of the Academic Integrity Policy and penalties may apply.

Studiosity is permitted unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission as detailed on the Learning Hub’s Canvas page.

Outside assessment tasks, generative AI tools may be used to support your learning. The AI in Education Canvas site contains a number of productive ways that students are using AI to improve their learning.

Learning support

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Support for students

The Support for Students Policy 2023 reflects the University’s commitment to supporting students in their academic journey and making the University safe for students. It is important that you read and understand this policy so that you are familiar with the range of support services available to you and understand how to engage with them.

The University uses email as its primary source of communication with students who need support under the Support for Students Policy 2023. Make sure you check your University email regularly and respond to any communications received from the University.

Learning resources and detailed information about weekly assessment and learning activities can be accessed via Canvas. It is essential that you visit your unit of study Canvas site to ensure you are up to date with all of your tasks.

If you are having difficulties completing your studies, or are feeling unsure about your progress, we are here to help. You can access the support services offered by the University at any time:

Support and Services (including health and wellbeing services, financial support and learning support)
Course planning and administration
Meet with an Academic Adviser

Weekly schedule

WK	Topic	Learning activity
Multiple weeks	Problem based learning	Workshop (6 hr)
Week 01	Cardiovascular Pathology 1	Lecture and tutorial (3.5 hr)
Week 02	Cardiovascular Pathology 2	Lecture (2 hr)
Week 02	Cardiovascular Pathology 2	Practical (2 hr)
Week 03	Cardiovascular Pathology 3	Lecture and tutorial (3.5 hr)
Week 04	Neurological Diseases 1	Lecture (2 hr)
Week 04	Neurological Diseases 1	Practical (2 hr)
Week 05	Neurological Diseases 2	Lecture and tutorial (3.5 hr)
Week 06	Endocrinopathies 1	Lecture (2 hr)
Week 06	Endocrinopathies 1	Practical (2 hr)
Week 07	Endocrinopathies 2	Lecture and tutorial (3.5 hr)
Week 08	Accessory Digestive Organ Diseases 1	Lecture (2 hr)
Week 08	Accessory Digestive Organ Diseases 1	Practical (2 hr)
Week 09	Accessory Digestive Organ Diseases 2	Lecture and tutorial (3.5 hr)
Week 10	Haematopathology 1	Lecture (1 hr)
Week 10	Haematopathology 1	Practical (2 hr)
Week 11	Haematopathology 2	Lecture and tutorial (3.5 hr)
Week 12	Oral and Maxillofacial Pathology 1	Lecture and tutorial (3.5 hr)
Week 13	Oral and Maxillofacial Pathology 2	Lecture (2 hr)
Week 13	Oral and Maxillofacial Pathology 2	Practical (2 hr)

Attendance and class requirements

Students must attend at least 80% of compulsory museum and microscope practicals for this unit, per the University Coursework Policy.

Attendance is recorded and will be used to support a case for absent fail (AF) where necessary.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

All readings for this unit can be accessed through the Library eReserve, available on Canvas.

Robbins Cotran Pathologic Basis of Disease; 10th edition; Vinay Kumar, Abul K. Abbas, Jon. C. Aster

Learning outcomes

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

Outcomes
Graduate qualities

At the completion of this unit, you should be able to:

LO1. Define and explain how different organ systems react to injury and adapt to pathology.
LO2. Interpret key mechanisms of pathogenic processes to synthesise original insights and predict outcomes.
LO3. Classify microscopic and macroscopic specimens to allow for evaluation and analysis of pathogenesis and disease.
LO4. Summarise and transfer problem-solving skills to predict the outcomes of novel situations related to disease pathogenesis.
LO5. Identify, evaluate and integrate scholarly information on disease pathogenesis for written and verbal communication to a learned audience.

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1	Depth of disciplinary expertise Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.
GQ2	Critical thinking and problem solving Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.
GQ3	Oral and written communication Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.
GQ4	Information and digital literacy Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.
GQ5	Inventiveness Generating novel ideas and solutions.
GQ6	Cultural competence Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.
GQ7	Interdisciplinary effectiveness Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.
GQ8	Integrated professional, ethical, and personal identity An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.
GQ9	Influence Engaging others in a process, idea or vision.

Outcome map

Learning outcomes	Graduate qualities
Learning outcomes

Responding to student feedback

This section outlines changes made to this unit following staff and student reviews.

In response to student feedback in 2023 more time has been allocated to all practical classes and the museum presentations will be staggered to improve the student workload. Drop-in sessions are now offered weekly for students to engage with the academic team. PBLs developed in 2023 were enjoyed and will be retained for 2024.

Additional information

Work, health and safety

We are governed by the Work Health and Safety Act 2011, Work Health and Safety Regulation 2011 and Codes of Practice. Penalties for non-compliance have increased. Everyone has a responsibility for health and safety at work. The University’s Work Health and Safety policy explains the responsibilities and expectations of workers and others and the procedures for managing WHS risks associated with University activities.

General Laboratory Safety Rules

No eating or drinking is allowed in any laboratory under any circumstances
A laboratory coat and closed-toe shoes are mandatory
Follow safety instructions posted in laboratories
In case of fire, follow instructions posted outside the laboratory door
First aid kits, eyewash and fire extinguishers are located in or immediately outside each laboratory
As a precautionary measure, it is recommended that you have a current tetanus immunisation. This can be obtained from University Health Service: unihealth.usyd.edu.au/

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.

Current students

Overview

Overview

Unit details and rules

Teaching staff

Assessment

Assessment

Assessment summary

Assessment criteria

Late submission

Academic integrity

Learning support

Learning support

Simple extensions

Special consideration

Using AI responsibly

Support for students

Weekly schedule

Weekly schedule

Attendance and class requirements

Study commitment

Required readings

Learning outcomes

Learning outcomes

Graduate qualities

Outcome map

Responding to student feedback

Responding to student feedback

Additional information

Additional information

Work, health and safety

Disclaimer

On this page

Useful links

Media

Student links

About us

Connect

Current students

CPAT3202: Pathogenesis of Human Disease 2

Semester 2, 2024 [Normal day] - Camperdown/Darlington, Sydney

Overview

Overview

Unit details and rules

Teaching staff

Assessment

Assessment

Assessment summary

Assessment criteria

Late submission

Academic integrity

Learning support

Learning support

Simple extensions

Special consideration

Using AI responsibly

Support for students

Weekly schedule

Weekly schedule

Attendance and class requirements

Study commitment

Required readings

Learning outcomes

Learning outcomes

Graduate qualities

Outcome map

Responding to student feedback

Responding to student feedback

Additional information

Additional information

Work, health and safety

Disclaimer

On this page

Useful links

Media

Student links

About us

Connect