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Unit outline_

IMMU2011: Immunobiology

Semester 1, 2023 [Normal day] - Remote

Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses mounted by animals, both vertebrates and invertebrates, plants and microbes themselves. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combating infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as the development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with an overview of immunobiology as a basic research science. We will explore the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Practical and workshop sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. Upon completion, you will have developed the foundations to undertake further studies in Biology, Animal Health, Immunology and Pathology. Ultimately, this could lead you to a career in medical research, biosecurity and/or Veterinary Science.

Unit details and rules

Academic unit Department of Medical Sciences
Credit points 6
Prerequisites
? 
BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1
Corequisites
? 
None
Prohibitions
? 
IMMU2911
Assumed knowledge
? 

CHEM1XX1 or CHEM1903

Available to study abroad and exchange students

Yes

Teaching staff

Coordinator Scott Stimpson, scott.stimpson@sydney.edu.au
Type Description Weight Due Length
Supervised exam
? 
Final exam
Final exam consisting of MCQs and SAQs
40% Formal exam period 2 hours
Outcomes assessed: LO1 LO2 LO3 LO4
Tutorial quiz Pre-practical quiz
MCQs about the content of the practical classes.
10% Multiple weeks 10 mins
Outcomes assessed: LO5
Online task Comprehension table
A short MCQ quiz about the Title & Abstract journal article.
5% Week 07
Due date: 04 Apr 2023 at 10:00
5 minutes
Outcomes assessed: LO1 LO4 LO3 LO2
Assignment Title and abstract written task
Written abstract of no more than 250 words.
15% Week 07
Due date: 04 Apr 2023 at 10:00
250 words
Outcomes assessed: LO1 LO2 LO3 LO4
Assignment group assignment Oral presentation
5 minute pre-recorded presentation about immune cells from blood smears.
15% Week 08
Due date: 20 Apr 2023 at 10:00
5 minutes
Outcomes assessed: LO1 LO2 LO3 LO4
Tutorial quiz Practical exam 2 (Theory of Practical Exam)
MCQs and SAQs relating to the content of the practical classes.
15% Week 13
Due date: 23 May 2023 at 10:00
60 Minutes
Outcomes assessed: LO4 LO5
group assignment = group assignment ?

Assessment summary

All assessment tasks.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2021 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name

Mark range

Description

High distinction

85 - 100

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at an exceptional standard
as defined by grade descriptors or exemplars established by the faculty
.

Distinction

75 - 84

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at a very high standard as
defined by grade descriptors or exemplars established by the faculty.

Credit

65 - 74

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at a good standard as
defined by grade descriptors or exemplars established by the faculty.

Pass

50 - 64

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at an acceptable standard
as defined by grade descriptors or exemplars established by the faculty
.

Fail

0 - 49

To be awarded to students who, in their performance in assessment
tasks, fail to demonstrate the learning outcomes for the unit at an
acceptable standard established by the faculty. This grade, with
corresponding mark, should also be used in cases where a student fails
to achieve a mandated standard in a compulsory assessment, thereby
failing to demonstrate the learning outcomes to a satisfactory standard.
In such cases the student will receive the mark awarded by the faculty
up to a maximum of 49.

For more information see guide to grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Any work submitted electronically after 11.59 pm on the due date will be considered to have been submitted late. For every calendar day up to and including ten calendar days after the due date, a penalty of 5% of the maximum awardable marks will be applied to late work. Any work submitted more than ten calendar days after the due date a mark of zero will be awarded.

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

Use of generative artificial intelligence (AI) and automated writing tools

You may only use generative AI and automated writing tools in assessment tasks if you are permitted to by your unit coordinator. If you do use these tools, you must acknowledge this in your work, either in a footnote or an acknowledgement section. The assessment instructions or unit outline will give guidance of the types of tools that are permitted and how the tools should be used.

Your final submitted work must be your own, original work. You must acknowledge any use of generative AI tools that have been used in the assessment, and any material that forms part of your submission must be appropriately referenced. For guidance on how to acknowledge the use of AI, please refer to the AI in Education Canvas site.

The unapproved use of these tools or unacknowledged use will be considered a breach of the Academic Integrity Policy and penalties may apply.

Studiosity is permitted unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission as detailed on the Learning Hub’s Canvas page.

Outside assessment tasks, generative AI tools may be used to support your learning. The AI in Education Canvas site contains a number of productive ways that students are using AI to improve their learning.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

WK Topic Learning activity Learning outcomes
Week 01 What is an immune system and why is it important? Lecture (1 hr) LO1
The components of the immune system Lecture (1 hr) LO1
Week 02 The Innate immune system Lecture (1 hr) LO1
Innate immune sensing Lecture (1 hr) LO1 LO2
Introduction to microscopy & immunohistology Practical (3 hr) LO1 LO5
Week 03 The Complement System Lecture (1 hr) LO1 LO2
MHC and antigen presentation Lecture (1 hr) LO1 LO2
Types of immunity Workshop (2 hr) LO1
Week 04 B cells and antibodies Lecture (1 hr) LO2
T cells Lecture (1 hr) LO1
Fundamental immunology laboratory techniques Practical (3 hr) LO5
Week 05 Initiation of lymphocyte responses Lecture (1 hr) LO1 LO4
Helper T cells Lecture (1 hr) LO2 LO3
Components of the immune system Workshop (2 hr) LO2
Week 06 Killer T Cells Lecture (1 hr) LO3 LO4
Immune system memory Lecture (1 hr) LO3 LO4
Agglutination, an example of antigen-antibody Interaction Practical (3 hr) LO4 LO5
Week 07 Cytokines: Types and key functions Lecture (1 hr) LO3 LO4
Immune Cell Movement: How do they get around? Lecture (1 hr) LO3 LO4
Defence mechanisms in plants and animals Workshop (2 hr) LO3
Week 08 Evolution of the Immune System Lecture (1 hr) LO3 LO4
Plant Immunology I Lecture (1 hr) LO3 LO4
Monoclonal antibodies in research and the clinic Practical (3 hr) LO4 LO5
Week 09 Plant Immunology II Lecture (1 hr) LO2 LO3
Veterinary Immunology I Lecture (1 hr) LO2 LO3
Week 10 Veterinary Immunology II Lecture (1 hr) LO2 LO3
Immunology & Disease: Host defense and vaccination Lecture (1 hr) LO1 LO3
Identifying immune cells Workshop (2 hr) LO3 LO4 LO5
Week 11 Immunology & Disease: Transplantation Lecture (1 hr) LO4
Immunology & Disease: Autoimmunity and Allergy Lecture (1 hr) LO1 LO2 LO4
Principles & practical applications of immunoassays Practical (3 hr) LO4 LO5
Week 12 Immunology & Disease: Resistance to COVID-19 Lecture (1 hr) LO4
Immune cells in health and diseases Workshop (2 hr) LO4

Attendance and class requirements

Attendance will be recorded from students' arrival date on campus or from Feburary 20th, whichever is the earliest. From Feburary 20th (week 1), students enrolled in this unit should engage with and study all online content, as directed in the Canvas site, including the submission of any required formative tasks and completion of any asynchronous activities.

It is expected that students attend at least 80% of the practicals and tutorials in this unit of study.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

Abbas, Lichtman and Pillai (2016) Basic Immunology: Functions & Disorders of The Immune System, 5th Edition

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. Differentiate the types of immunity
  • LO2. Compare and contrast the cells and molecules of immunity in more than one organism
  • LO3. Describe, using examples, how plants and animals recognise and respond to pathogens
  • LO4. Demonstrate how principles of immunology can be used to tackle health problems
  • LO5. Perform experiments using cutting edge immunology techniques, then interpret and communicate the data generated

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

This section outlines changes made to this unit following staff and student reviews.

The pre-practical quizzes time limit has been increased from 5 to 10 minutes per student feedback from previous years and will be opened and completed prior to practical classes.

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.