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Synthetic biology: catalysis inside protein cages

Visit our group website for the latest information - laugroup.netNature is a master of self-assembly, constructing functional nanoscale architectures from simple protein building bl more...

Supervisor(s): Lau, Yu Heng (Dr)

Fluorescent sensing of labile metal pools

Metals play an important role in biology, but there are only limited tools to study their functions and interactions. In this project we will develop new fluorescent tools to study more...

Supervisor(s): New, Elizabeth (Associate Professor)

Discovery and validation of new ceramide synthase inhibitors to treat metabolic disease

Ceramide synthase enzyme isoforms 1, 5, and 6, are heavily implicated as drivers of obesity, insulin resistance, and diabetes. Targeting these enzymes is expected to yield new thera more...

Supervisor(s): Don, Anthony (Associate Professor), Qi, Jacob (Dr)

Fluorescent sensing arrays to study metal ions in the environment

This project involves developing new methods to detect and measure metal ions from complex solutions such as river and blood. more...

Supervisor(s): New, Elizabeth (Associate Professor)

Organic chemistry: Anti-cancer peptide therapeutics

Visit our group website for the latest information - laugroup.net more...

Supervisor(s): Lau, Yu Heng (Dr)

Computational Modeling of Immune Cell Chemotaxis and Swarming

 Using computational simulation to form and evaluate hypotheses concerning the factors that drive immune cell motility, such as neutrophil swarming, during inflammation. more...

Supervisor(s): Read, Mark (Dr)

Pharmacological targeting of sphingosine 1-phosphate receptors to promote remyelination in Alzheimer’s disease and multiple sclerosis

In this project you will investigate a new molecular pathway that is required for normal myelin formation, and the therapeutic potential of targeting this pathway to promote remyeli more...

Supervisor(s): Don, Anthony (Associate Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Metal Ion Sensors for Medicinal and Environmental Applications

Metal cations like Zn(II), Cu and K(I) play a raft of important signalling roles in our bodies; others such as Hg(II), Cd(II) and Pb(II) are toxic pollutants in the environment. more...

Supervisor(s): Rutledge, Peter (Professor), Canning, John (Honorary Professor)

Heart Failure, Oxygen and HIF

This project will investigate the physiological and metabolic changes seen in the heart in models of obstructive sleep apnoea. more...

Supervisor(s): Cook, Kristina (Dr), Farnham, Melissa (Dr)