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Carboranes as unique boron frameworks in medicinal chemistry

Boron-based drugs are increasingly being investigated in many disease categories, with numerous pharmaceutical companies (e.g. GSK, Anacor, and Takeda) dramatically expanding their more...

Supervisor(s): Rendina, Louis (Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Expanding the scope of the Stetter reaction

Opportunities exist to build complex organic molecules using the organocatalytic Stetter reaction. more...

Supervisor(s): McErlean, Christopher (Associate Professor)

Why are Ionic Liquids Extraordinary Solvents?

The use of ionic liquids has exploded over the last decades as solvents for unusual or difficult chemical syntheses.  These liquids consist solely of ions and have melting poin more...

Supervisor(s): Warr, Gregory (Professor)

Catalysis of Sustainable Processes

Available projects involve the development of novel catalysts for the generation of hydrogen by splitting water with sunlight, for biomass conversion, for green industrial oxidation more...

Supervisor(s): Masters, Tony (Professor)

Laboratory Exobiology: Prebiotic Environments in Ionic Liquids?

Life in the universe is widely presumed only to be viable in the ‘Goldilocks zone’ around a star, where liquid water is available.  Some have speculated that Titan more...

Supervisor(s): Warr, Gregory (Professor)

Novel Electrodes for rapid electrophysiological recording

Rapid monitoring of emergencies including heart attack and stroke are limited by electrode movements.  This project aims at using a range of methods to improve electrodes inclu more...

Supervisor(s): McEwan, Alistair (Professor), Jin, Craig (Associate Professor), Leong, Philip (Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Development of novel anti-cancer metastasis agents derived from omega-3 fatty acid metabolites

At present we have no therapies that prevent cancer spread. In this project we will develop novel w-3 fatty acid epoxide analogues that inhibit tumour metastasis. These derivatives more...

Supervisor(s): Murray, Michael (Professor)