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Clinical outcomes analysis of patients who undergo laparoscopic cholecystectomy for complex (grade 4) cholecystitis

The Upper GI surgery department at RNSH is a tertiary referral unit which has treated many patients with gallbladder disease over the past 20 years. There is a large prospective cli more...

Supervisor(s): Hugh, Thomas J (Professor)

Health burden of chronic diseases

This research project aims to model the health burden of chronic diseases and their comorbid conditions using Markov models, Bayesian statistics and Complex network. more...

Supervisor(s): Uddin, Shahadat (Dr)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

The nutritional geometry of non-alcoholic fatty liver disease, cardio-metabolic health and lifespan

The global epidemic of obesity and type 2 diabetes (T2D) has been linked to increased consumption of ‘western diets’ containing an abundance of processed foods rich in s more...

Supervisor(s): Simpson, Stephen (Professor), Wali, Jibran (Dr)

Modelling plasma synthesis of nanoparticles for non-invasive diagnosis and targeted treatment of disease

This project will develop multiphysics models of a low temperature capacitively coupled plasma reactor to engineer functionalised nanoparticles for biomedical applications.This proj more...

Supervisor(s): Bilek, Marcela (Professor), Baldry, Mark (Dr)

Towards safe and effective pharmacological care of people with dementia

This research program aims to optimise the prescribing of medications in people with dementia.  more...

Supervisor(s): Tan, Edwin (Dr)

Multi-omic responses to dietary change: insights from poultry

Diet is a crucial mechanism by which organisms interact with their environment. The body responds to the food it receives to control nutrient uptake and moderate physiological pathw more...

Supervisor(s): Grueber, Catherine (Dr), Liu, Sonia (Dr), Whittington, Camilla (Dr)

Clinical outcomes analysis of patients who undergo resection for malignant Hepato-Biliary tumours

Available projectsClinical and molecular markers of early tumour recurrence in patients with malignant hepato-biliary tumours,Clinical and molecular markers of metastatic potential more...

Supervisor(s): Hugh, Thomas J (Professor)

Insulin-mediated regulation of adipocyte lipolysis

Insulin, a hormone that is released after a meal, regulates many aspects of metabolism including a process called lipolysis that involves the release of fatty acids into the circula more...

Supervisor(s): James, David (Professor)

Modelling atmospheric plasma processes for biofunctionalization in additive manufacturing

This project will develop multiphysics models of atmospheric pressure plasma systems to engineer interfaces and biofunctionalised scaffolds in 3D bioprinting.  The Applied Phys more...

Supervisor(s): Bilek, Marcela (Professor), Baldry, Mark (Dr)