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Whole genome CRISPR screening to define drug mechanism of action

This project will involve new whole genome CRISPR editing strategies, coupled with bioinformatics analysis, to identify the complete molecular mechanism of action for relevant human more...

Supervisor(s): Neely, Greg (Associate Professor)

CRISPR-based genome editing

The recent development of genome editing technology is perhaps the single biggest technical breakthrough in the history of life sciences, allowing for near complete control over euk more...

Supervisor(s): Neely, Greg (Associate Professor)

HUMAN MINIBRAINS GROWN FROM STEM CELLS

This project will involve CRISPR genome editing strategies combined with human stem cell derived mini-brains to investigate new neuronal factors that control development, cognitive more...

Supervisor(s): Neely, Greg (Associate Professor)

Using Gene editing to cure genetic neurological disorders

This project is an opportunity for a PhD student who is interested in genetic disorders of the brain and who is prepared to work at the cutting edge of technology. Genetic neurologi more...

Supervisor(s): Gold, Wendy (Dr)

Gene editing of human stem cells and to better understand chronic pain disease

This project involves the use of human stem cells to generate pain sensing neurons and CRISPR gene editing to identify new pain killers. A complimentary scholarship for this pr more...

Supervisor(s): Neely, Greg (Associate Professor)

Gene function and RNA processing in gut endoderm development

This project aims to unravel the impact of RNA processing on the function the targets of a RNA binding protein in the development of the embryonic gut and the associated organs. more...

Supervisor(s): Fossat, Nicolas (Dr), Tam, Patrick (Professor)

Head Development: Intersection of transcriptional and signalling activities

This project is designed to test the hypothesis that head formation during embryogenesis is controlled by a multitude of interacting transcriptional and signalling activities and t more...

Supervisor(s): Tam, Patrick (Professor), Fossat, Nicolas (Dr)

The DNA replication stress response

Genome integrity in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Gene and Cell therapy for treating corneal diseases

Two research projects existing under this board area :1. Develop in vivo gene editing technique to treat corneal diseases; and 2. Sequencing and mapping gene and protein interaction more...

Supervisor(s): You, Jingjing (Dr), Sutton, Gerard (Professor)

Strengthening brittle bones

Osteogenesis imperfecta (OI) or "brittle bone disease" can be caused by a range of proteins involved with the bone matrix. Children with OI are prone to fracture, which can reduce m more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor), Munns, Craig (Associate Professor)