This unit of study is intended to provide knowledge in a number of fundamental areas that guide and provide evidence to support the safe, effective and appropriate use of medicines. These fundamental areas of knowledge start with an understanding of the relationship between drugs interacting with target sites in the body and the effect produced (i.e. pharmacodynamic principles) and understanding the physiological and physicochemical factors that influence the movement of drugs around the body and the time course of exposure of body tissues and blood to drugs (i.e. pharmacokinetics). These principles involve developing concepts and mathematical relationships to explain drug activity in patients and to guide appropriate drug dosage regimen selection. To support this, relevant mathematical and statistical principles involving calculus are introduced during this unit of study. This unit will also explore reasons behind variability in response to medicines among different individuals. The effects of disease, other drugs, demographics and the genetic basis for variable response will be introduced. Students are also exposed to the notion that medicines may produce adverse effects (as well as beneficial ones). The mechanisms underlying adverse reactions to drugs and how these are classified are explored as are the principles for detecting and avoiding these unwanted effects. This unit will introduce students to methods that are used to provide evidence of efficacy and safety of different therapeutic options and to define the place in therapy of these options. Principles that underpin evidence based medicine and the notion of levels of evidence are introduced. Exposure to these principles is intended to develop in students a basic understanding of how to critically evaluate therapeutic options.
Unit details and rules
Academic unit | Pharmacy |
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Credit points | 6 |
Prerequisites
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PHAR1811 and PHAR1812 and PHAR1822 and (BIOL1XX7 or MBLG1XX1) |
Corequisites
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None |
Prohibitions
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None |
Assumed knowledge
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None |
Available to study abroad and exchange students | Yes |
Teaching staff
Coordinator | Sophie Stocker, sophie.stocker@sydney.edu.au |
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Lecturer(s) | Andrew McLachlan, andrew.mclachlan@sydney.edu.au |
Sophie Stocker, sophie.stocker@sydney.edu.au | |
Fanfan Zhou, fanfan.zhou@sydney.edu.au |