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PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)

Microscale Technology and 3D Printing for Therapeutic Delivery and Tissue Engineering

Dr. Kang is working in the area of drug delivery / testing and tissue engineering by using micro- and nano- scale technologies.For drug delivery, several drug-device combination pro more...

Supervisor(s): Kang, Lifeng (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)

Chronic Hepatitis B: from virological concepts to cure

We are seeking passionate Ph.D. and Masters candidates to conduct a research project on understanding how hepatitis B virus persists in the liver to ultimately design a cure for chr more...

Supervisor(s): Tu, Thomas (Dr), Douglas, Mark W (Associate Professor)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

STUDIES OF VARIABLE OR CONSERVED SURFACE PROTEIN SITES OF NEISSERIA MENINGITIDIS AS EPITOPES FOR STRAIN-SPECIFIC VACCINES OR BROAD-STRAIN (UNIVERSAL) VACCINES

The gram-negative Neisseria Meningititis (NM) remains a significant microbial problem and particularly lethal for the very young. Serogroup B strains are particularly troublesome an more...

Supervisor(s): Lynch, Garry (Dr)

Develop single-molecule and super-resolution microscopy imaging technologies in the cardiovascular disease

This project will focus on development, improvement, and application of single-molecule tracking and super-resolution imaging, such as TIRF, HiLo, PALM, STORM, Lattice Light-Sheet M more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Effect of maternal high glycemic index diets on offspring metabolic phenotype

We are uncovering fascinating effects of different sugars (glucose, fructose, sucrose and isomaltulose) on development of embryos and offspring.  High glucose fed mice are sign more...

Supervisor(s): Bell-Anderson, Kim (Dr)

Brain Cancer and Hypoxia

Aggressive brain tumours, including adult glioblastomas and pediatric DIPGs, are difficult to treat. Survival rates have improved very little over the last 30 years indicating a nee more...

Supervisor(s): Cook, Kristina (Dr)

Modelling plasma synthesis of nanoparticles for non-invasive diagnosis and targeted treatment of disease

This project will develop multiphysics models of a low temperature capacitively coupled plasma reactor to engineer functionalised nanoparticles for biomedical applications.This proj more...

Supervisor(s): Bilek, Marcela (Professor), Baldry, Mark (Dr)