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Research_

Tissue engineering and regenerative medicine

Artificial implants repairing damaged tissue and organs

Our mission is to develop a set of interfaced, artificial solutions that repair and replace malfunctioning body parts and damaged tissue.

  • Improving biocapacity of implanted devices
  • Repairing wound ulcers
  • Delivering bespoke engineered blood vessels and 3D vasculature
  • Developing novel materials and in silico predictive models of human tissue

In light of increasing rates of obesity and diabetes, there is a profound and increasing need for constructs that can be ‘plugged into’ a patient to repair damaged tissue and malfunctioning organs.

Current artificial implants do not typically direct local cell growth, resulting in delayed healing, substantial fibrosis (scar tissue development) or both. Additionally, the current generation of organ-like implants lacks functional vasculature to nurture nutrient and gas transfer, leading to reduced function and local necrosis.

Our research addresses these gaps by engineering biologically directing surfaces and three-dimensional constructs that will direct and enhance local tissue performance.

This research will empower governments to regulate private behaviour to promote public health. Legal strategies like new legislation, heightened regulatory enforcement and litigation can be a highly cost-effective mechanism to deliver health benefits to the population.

 

Project lead

Professor Tony Weiss
Professor Tony Weiss
“The Charles Perkins Centre provides an extraordinary, dynamic and well-equipped building.”
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