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Obesity and insulin resistance in children and adolescents.

Studies on various aspects of obesity and insulin resistance in children and young people – covering management, prevention and pathophysiology. There is potential for a range more...

Supervisor(s): Baur, Louise (Professor), Garnett, Sarah (Dr), Cowell, Chris (Professor), Hardy, Louise (Dr)

Refining cell-based therapies to cure diabetes

The most promising route for a cure for type 1 diabetes is the use of insulin-secreting cells to replace those that have died. more...

Supervisor(s): Thorn, Peter (Professor)

Skeletal muscle lipid metabolism in type 2 diabetes and obesity

It has been known for over 20 years that excessive amounts of lipid within tissue such as skeletal muscle are deleterious for blood glucose regulation - especially insulin regulatio more...

Supervisor(s): Hoy, Andrew (Dr)

The effect of simulated shift work on food desirability and metabolism

The aim of this research is to ascertain the impact of a simulated night shift rotation on food desirability in order to increase our understanding of the mechanisms that underpin i more...

Supervisor(s): Phillips, Craig (Dr), Comas Soberats, Maria (Dr)

Complementary medicine approaches to weight loss and the prevention of type 2 diabetes

Type 2 diabetes mellitus is the fastest growing chronic illness in Australia, and over 3.2 million people are estimated to have pre-diabetes and diabetes, with a further 275 individ more...

Supervisor(s): Fuller, Nick (Dr)

Analysis of the genetic basis of neurodegenertative disorders in the vertebrate model organism zebrafish

The zebrafish as a vertebrate developmental genetics model organism shall be used to ascertain the effects of human mutations implicated in neurodegenerative disease. With the aim t more...

Supervisor(s): Becker , Thomas (Professor), Rinkwitz, Silke (Dr)

Functional analysis of genes implicated in hypothalamic obesity using zebrafish as a vertebrate developmental genetics model system

A gene with implication in obesity shall be analysed for its regulation and function in the brain by using the zebrafish as experimental system. Transgenic zebrafish lines shall be more...

Supervisor(s): Rinkwitz, Silke (Dr), Becker , Thomas (Professor)

Regulation and function of developmental control genes during cell type specification in the developing hypothalamus

The function and regulation of important developmental genes controlling differentiation of neuronal subpopulations in the hypothalamus shall be studied in the vertebrate model orga more...

Supervisor(s): Rinkwitz, Silke (Dr), Becker , Thomas (Professor)

A study to investigate the efficacy of dexamphetamine compared to placebo for treating obesity complicated by obstructive sleep apnoea

The project represents a new approach to the pharmacological treatment of obesity. It uses dexamphetamine but unlike most drug trials using appetite suppressants, the focus is on th more...

Supervisor(s): Poulton, Alison (Dr)