University of Sydney Handbooks - 2013 Archive

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Table 1: Pharmacology

Table 1 lists units of study available to students in the Bachelor of Science and combined degrees. The units are available to students enrolled in other degrees in accordance with their degree resolutions.

Unit of study Credit points A: Assumed knowledge P: Prerequisites C: Corequisites N: Prohibition Session

Pharmacology

For a major in Pharmacology, the minimum requirement is 24 credit points from senior units of study listed in this subject area.
Intermediate units of study
The completion of MBLG1001/1901 is highly recommended.
PCOL2011
Pharmacology Fundamentals
6    P (6 credit points of Junior Chemistry) and (6 credit points of Junior Biology or MBLG1001 or MBLG1901)
N PCOL2001


BMedSci students may not take this unit.
Semester 1
PCOL2012
Pharmacology: Drugs and People
6    A PCOL2011
P (6 credit points of Junior Chemistry) and (6 credit points of Junior Biology or MBLG (1001 or 1901)).
N PCOL2002, PCOL2003
Semester 2
Senior units of study
PCOL3011
Toxicology
6    P PCOL2001; OR PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802)
N PCOL3001, PCOL3901, PCOL3911
Semester 1
PCOL3911
Toxicology (Advanced)
6    P Distinction average in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3001, PCOL3901, PCOL3011
Semester 1
PCOL3012
Drug Design and Development
6    P PCOL2001; OR PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802).
N PCOL3001, PCOL3901, PCOL3912
Semester 1
PCOL3912
Drug Design and Development (Adv)
6    P Distinction average in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3001, PCOL3901, PCOL3012
Semester 1
PCOL3021
Drug Therapy
6    P PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802).
N PCOL3002, PCOL3902, PCOL3921
Semester 2
PCOL3921
Drug Therapy (Advanced)
6    P Average grade Distinction in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3002, PCOL3902, PCOL3021
Semester 2
PCOL3022
Neuropharmacology
6    P PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802).
N PCOL3002, PCOL3902, PCOL3922
Semester 2
PCOL3922
Neuropharmacology (Advanced)
6    P Average grade Distinction in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3002, PCOL3902, PCOL3022
Semester 2

Pharmacology

For a major in Pharmacology, the minimum requirement is 24 credit points from senior units of study listed in this subject area.
Intermediate units of study
The completion of MBLG1001/1901 is highly recommended.
PCOL2011 Pharmacology Fundamentals

Credit points: 6 Teacher/Coordinator: Dr Brent McParland Session: Semester 1 Classes: Two 1 hour lectures per week; workshops and laboratory sessions. Prerequisites: (6 credit points of Junior Chemistry) and (6 credit points of Junior Biology or MBLG1001 or MBLG1901) Prohibitions: PCOL2001 Assessment: One 2 hour exam, in semester quizzes and reports (100%) Associated degrees: B Sc, B Sc (Molecular Biology & Genetics), B Sc (Nutrition), UG Study Abroad Program.
Note: BMedSci students may not take this unit.
This unit of study provides the fundamental grounding in four basic areas in Pharmacology: (1) principles of drug action (2) pharmacokinetics and drug metabolism (3) experimental design and autonomic pharmacology, and (4) drug design. The delivery of material involves lectures, practicals, computer-aided learning and problem-based workshops. Practical classes provide students with the opportunity of acquiring technical experience and teamwork skills. Problem-based workshops are based on real-life scenarios of drug use in the community. These workshops require students to integrate information obtained in lectures in order to provide solutions to the problems. Online quizzes accompany each module for self assessment.
Textbooks
Rang & Dale's Pharmacology, 7th edn; Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson (Churchill Livingstone).
PCOL2012 Pharmacology: Drugs and People

Credit points: 6 Teacher/Coordinator: Dr Hilary Lloyd Session: Semester 2 Classes: Two 1 hour lectures per week; workshops and laboratory sessions. Prerequisites: (6 credit points of Junior Chemistry) and (6 credit points of Junior Biology or MBLG (1001 or 1901)). Prohibitions: PCOL2002, PCOL2003 Assumed knowledge: PCOL2011 Assessment: One 2 hour exam, in-semester quizzes, reports (100%) Associated degrees: B Med Sc, B Sc, B Sc (Molecular Biology & Genetics), B Sc (Nutrition), UG Study Abroad Program.
This unit of study examines four important areas of Pharmacology: (1) drug action in the nervous system (2) drug discovery and development (3) pharmacotherapy of inflammation, allergy and gut disorders, and (4) drugs of recreation, dependence and addiction. The delivery of material involves lectures, practicals, computer-aided learning and problem-based workshops. Practical classes provide students with the opportunity of acquiring technical experience and teamwork. Problem-based workshops are based on real-life scenarios of drug use in the community. These workshops require students to integrate information obtained in lectures in order to provide solutions to the problems. Online quizzes accompany each module.
Textbooks
Rang HP, Dale MM, Ritter JM & Flower RJ. Pharmacology. 6th ed. Churchill Livingstone, 2007.
Senior units of study
PCOL3011 Toxicology

Credit points: 6 Teacher/Coordinator: Dr Slade Matthews Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: PCOL2001; OR PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802) Prohibitions: PCOL3001, PCOL3901, PCOL3911 Assessment: One 2 hour exam, tutorial presentations, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study is designed to introduce students with a basic understanding of pharmacology to the discipline of toxicology. It considers the toxicology associated with therapeutic drugs (adverse drug reactions) and the associated issue of drug interactions. The pharmacogenetic basis of adverse reactions is also considered. The unit also considers aspects of environmental toxicology, particularly toxic reactions to environmental agents such as asbestos and pesticides, and its effects on different target organs (lung, liver, CNS). As a final consequence of exposure to toxins, the biology and causes of cancer are discussed. As part of the unit students are introduced to basic ideas about the collection and analysis of data from human and animal populations, both in the structured situation of clinical trials, forensic problems and in analysis of retrospective data.
Textbooks
Klaasen, Curtis D. Casarett and Doull's Toxicology: The Basic Science of Poisons. 7 ed. McGraw Hill. 2008.
PCOL3911 Toxicology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Slade Matthews Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: Distinction average in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3001, PCOL3901, PCOL3011 Assessment: One 2 hour exam, tutorial presentations, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit will consist of the lecture and practical components of PCOL3011. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Klaasen, Curtis D. Casarett and Doull's Toxicology: The Basic Science of Poisons. 7 ed. McGraw Hill. 2008.
PCOL3012 Drug Design and Development

Credit points: 6 Teacher/Coordinator: Dr Lenka Munoz Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: PCOL2001; OR PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3001, PCOL3901, PCOL3912 Assessment: One 2 hour exam, in class quizzes, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and ACE inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.
Textbooks
Patrick, Graham L. An Introduction to Medicinal Chemistry. 4th edition. Oxford University Press. 2009.
PCOL3912 Drug Design and Development (Adv)

Credit points: 6 Teacher/Coordinator: Dr Lenka Munoz Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: Distinction average in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3001, PCOL3901, PCOL3012 Assessment: One 2 hour exam, in class quizzes, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit will consist of the lecture and practical components of PCOL3012. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Patrick, Graham L. An Introduction to Medicinal Chemistry. 4th edition. Oxford University Press. 2009.
PCOL3021 Drug Therapy

Credit points: 6 Teacher/Coordinator: Dr Margaret Sunde Session: Semester 2 Classes: Two 1 hour lectures per week, four 1 hour tutorials, two 4 hour practical/computer laboratories, elective project (equivalent to three 4 hour practicals). Prerequisites: PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3002, PCOL3902, PCOL3921 Assessment: One 2 hour exam, tutorial and practical assignments and elective project (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study builds on pharmacological knowledge acquired in the intermediate PCOL and BMED units of study with a major emphasis on gaining an understanding of the scientific basis of drug therapy. Lecture topics, tutorials and laboratory sessions cover drug treatment of arthritis and asthma, cardiovascular disorders, microbial infections and cancer. Elective projects relate to current research areas in Pharmacology.
Textbooks
Rang, HP. Dale, MM. Ritter, JM and Flower, RJ: Pharmacology, 6th ed. Churchill Livingstone, 2007.
PCOL3921 Drug Therapy (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Margaret Sunde Session: Semester 2 Classes: Two 1 hour lectures per week, four 1 hour tutorials, two 4 hour practical/computer laboratories, elective project (equivalent to three 4 hour practicals). Prerequisites: Average grade Distinction in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3002, PCOL3902, PCOL3021 Assessment: One 2 hour exam, tutorial and practical assignments and elective project (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study builds on pharmacological knowledge acquired in the intermediate PCOL and BMED units of study with a major emphasis on gaining an understanding of the scientific basis of drug therapy. Lecture topics, tutorials and laboratory sessions cover drug treatment of arthritis and asthma, cardiovascular disorders, microbial infections and cancer. Elective projects relate to current research areas in Pharmacology.
Textbooks
Rang, HP. Dale, MM. Ritter, JM and Flower, RJ: Pharmacology, 6th ed. Churchill Livingstone, 2007.
PCOL3022 Neuropharmacology

Credit points: 6 Teacher/Coordinator: Dr Tina Hinton Session: Semester 2 Classes: Two 1 hour lectures per week, five 1 hour tutorials, three 3 hour practicals, elective project (equivalent to three 4 hour practicals). Prerequisites: PCOL2011 and PCOL2012. For BMedSci: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3002, PCOL3902, PCOL3922 Assessment: One 2 hour theory exam, tutorial presentation, practical report, lecture quizzes and elective project (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study builds on pharmacological knowledge acquired in the intermediate PCOL and BMED units of study with a major emphasis on gaining an understanding of neuropharmacology. The neuropharmacology of the major neurotransmitters and their role in neuropsychiatric diseases is explored together with the treatment of conditions such as Alzheimer's disease, movement disorders, stroke, depression, anxiety, epilepsy, pain and schizophrenia. Elective projects relate to current research areas in Pharmacology.
Textbooks
Nestler, EJ, Hyman, SE and Malenka, RC. Molecular Neuropharmacology: A Foundations for Clinical Neuroscience, 2nd ed. McGraw Hill, 2009.
PCOL3922 Neuropharmacology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Tina Hinton Session: Semester 2 Classes: Two 1 hour lectures per week, five 1 hour tutorials, three 3 hour practicals, elective project (equivalent to three 4 hour practicals). Prerequisites: Average grade Distinction in PCOL2011 and PCOL2012. For BMedSci: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3002, PCOL3902, PCOL3022 Assessment: One 2 hour theory exam, tutorial presentation, practical report, lecture quizzes and elective project (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study builds on pharmacological knowledge acquired in the intermediate PCOL and BMED units of study with a major emphasis on gaining an understanding of neuropharmacology. The neuropharmacology of the major neurotransmitters and their role in neuropsychiatric diseases is explored together with the treatment of conditions such as Alzheimer's disease, movement disorders, stroke, depression, anxiety, epilepsy, pain and schizophrenia. Elective projects relate to current research areas in Pharmacology.
Textbooks
Nestler, EJ, Hyman, SE and Malenka, RC. Molecular Neuropharmacology: A Foundations for Clinical Neuroscience, 2nd ed. McGraw Hill, 2009.