Dr Kate Edwards

Ph.D. University of Birmingham, UKBSc (HONS) Cardiff University, UK
Lecturer

C43K - K Block Cumberland Campus
The University of Sydney

Telephone 90367396
Fax 93519204

Website Exercise Physiology and Nutrition Research Team

Biographical details

Kate's main interests involve the positive effects of exercise on immune function and health; her research involves the acute effects of a single exercise bout, and the chronic effects of exercise training.

In particular she is interested in how a short exercise task can enhance the response to vaccination, an effect she has shown in the responses to influenza, meningococcal and pneumococcal vaccines. This research has received funding from the Bill & Melinda Gates Foundation and Action Medical Research, as well as media interest, including articles in the New York Times and ‘Men's Health' magazine. Kate is now focussed on the clinical applicability of this effect in different populations.

Research interests

The role that ‘exercise as medicine' plays in health is a major part of Kate's research and teaching. She is interested in the effects of exercise training in chronic disease, and the role of immune modulation as a mechanism and as a monitoring tool. In addition her sport research includes examination of training effects on the immune response.Kate's work has developed into examination of other behavioural factors, such as sleep and psychological stress, on immune function and regulation in health and disease.

Dr. Edwards is a member of the Exercise Physiology and Nutrition research team:

http://sydney.edu.au/health-sciences/research/exercise-physiology/index.shtml

Teaching and supervision

Kate's teaching focuses on exercise immunology, as well as application of exercise training in disease populations.

Selected grants

2014

  • Reducing adverse reactions and boosting immune response to HPV vaccination with exercise; Edwards K, Booy R, Skinner R; Financial Markets Foundation for Children/Financial Markets Foundation for Children Research Grants.
  • The impact of whole body cryotherapy and cold plunge pool exposure on muscle function, damage and immune and inflammatory markers after eccentric exercise; Edwards K, Caillaud C; Australian Sports Commission/Research Support.

2012

  • Boosting Influenza Vaccine Responses in the Elderly using a Brief Bout of Exercise; Edwards K; Sanofi Pasteur Australia/Research Support.

2011

  • Using a brief bout of exercise as a novel adjuvant to enhance the efficacy of pneumococcal vaccination in immunocompromised populations; Edwards K; Bill & Melinda Gates Foundation/Research Support.
  • Boosting influenza vaccinereponses in the eldery using a briecf bout of exercise; Edwards K; Clive & Vera Ramaciotti Foundation/Awards for Biomedical Research: Establishment Gifts.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Edwards, K., Mills, P. (2013). Physical activity, stress, and immune function. In Panteleimon Ekkekakis (Eds.), Routledge Handbook of Physical Activity and Mental Health, (pp. 342-355). Abingdon: Routledge.
  • Edwards, K., Mills, P. (2011). Interaktionen zwischen dem endokrinen, dem zentralnervösen und dem Immunsystem. In Ulrike Ehlert, Roland von Kanel (Eds.), Psychoendokrinologie und Psychoimmunologie, (pp. 111-127). Berlin, Germany: Springer-Verlag.
  • Burns, V., Phillips, A., Edwards, K. (2007). Vaccination. In George Fink (Eds.), Encyclopedia of Stress, (pp. 813-817). UK: Academic Press Elsevier.

Journals

  • Edwards, K., Kamat, R., Tomfohr, L., Ancoli-Israel, S., Dimsdale, J. (2014). Obstructive sleep apnea and neurocognitive performance: the role of cortisol. Sleep Medicine, 15(1), 27-32. [More Information]
  • Turner, J., Campbell, J., Edwards, K., Howarth, L., Pawelec, G., Aldred, S., Moss, P., Drayson, M., Burns, V., Bosch, J. (2014). Rudimentary signs of immunosenescence in cytomegalovirus-seropositive healthy young adults. Age, 36(1), 287-297. [More Information]
  • Pascoe, A., Fiatarone Singh, M., Edwards, K. (2014). The effects of exercise on vaccination responses: A review of chronic and acute exercise interventions in humans. Brain, Behavior, and Immunity, 39, 33-41. [More Information]
  • Edwards, K., Booy, R. (2013). Effects of exercise on vaccine-induced immune responses. Human Vaccines & Immunotherapeutics, 9(4), 907-910. [More Information]
  • Edwards, K., Pung, M., Tomfohr, L., Ziegler, M., Campbell, J., Drayson, M., Mills, P. (2012). Acute exercise enhancement of pneumococcal vaccination response: A randomised controlled trial of weaker and stronger immune response. Vaccine, 30(45), 6389-6395. [More Information]
  • Wilson, K., Tomfohr, L., Edwards, K., Knott, C., Hong, S., Redwine, L., Calfas, K., Rock, C., von Kanel, R., Mills, P. (2012). Effects of aerobic fitness and adiposity on coagulation biomarkers in men vs. women with elevated blood pressure. European Journal of Cardiovascular Medicine, 2(2), 122-128. [More Information]
  • Sadja, J., Tomfohr, L., Jimenez, J., Edwards, K., Rock, C., Calfas, K., Mills, P. (2012). Higher Physical Fatigue Predicts Adherence to a 12-Week Exercise Intervention in Women With Elevated Blood Pressure. Health Psychology, 31(2), 156-163. [More Information]
  • Tomfohr, L., Edwards, K., Dimsdale, J. (2012). Is obstructive sleep apnea associated with cortisol levels? A systematic review of the research evidence. Sleep Medicine Reviews, 16(3), 243-249. [More Information]
  • Tomfohr, L., Pung, M., Edwards, K., Dimsdale, J. (2012). Racial differences in sleep architecture: The role of ethnic discrimination. Biological Psychology, 89(1), 34-38. [More Information]
  • Edwards, K., Campbell, J. (2011). Acute Exercise as an Adjuvant to Influenza Vaccination. American Journal of Lifestyle Medicine, 5(6), 512-517. [More Information]
  • Edwards, K., Wilson, K., Sadja, J., Ziegler, M., Mills, P. (2011). Effects on blood pressure and autonomic nervous system function of a 12-week exercise or exercise plus DASH-diet intervention in individuals with elevated blood pressure. Acta Physiologica, 203, 343-350.
  • Edwards, K., Tomfohr, L., Mills, P., Bosch, J., Ancoli-Israel, S., Loredo, J., Dimsdale, J. (2011). Macrophage Migratory Inhibitory Factor (MIF) May Be a Key Factor in Inflammation in Obstructive Sleep Apnea. Sleep, 34(2), 161-163.
  • Shoucri, B., Edwards, K., Schmid-Schonbein, G., Mills, P. (2011). Plasma-stimulated pseudopod formation is increased in patients with elevated blood pressure. Hypertension Research, 34(6), 787-789. [More Information]
  • Edwards, K., Bosch, J., Engeland, C., Cacioppo, J., Marucha, P. (2010). Elevated Macrophage Migration Inhibitory Factor (MIF) is associated with depressive symptoms, blunted cortisol reactivity to acute stress, and lowered morning cortisol. Brain, Behavior, and Immunity, 24(7), 1202-1208. [More Information]
  • Edwards, K., Campbell, J., Ring, C., Drayson, M., Bosch, J., Downes, C., Long, J., Lumb, J., Merry, A., Paine, N., et al (2010). Exercise intensity does not influence the efficacy of eccentric exercise as a behavioural adjuvant to vaccination. Brain, Behavior, and Immunity, 24(4), 623-630. [More Information]
  • Edwards, K., Sheu, B., Hong, S., Penn, A., Schmid-Schonbein, G., Mills, P. (2010). Leukocyte membrane bleb and pseudopod formation in hypertension. Journal of Human Hypertension, 24(10), 684-686.
  • Anane, L., Edwards, K., Burns, V., Veldhuijzen Van Zanten, J., Drayson, M., Bosch, J. (2010). Phenotypic characterization of cd T cells mobilized in response to acute psychological stress. Brain, Behavior, and Immunity, 24(4), 608-614. [More Information]
  • Campbell, J., Edwards, K., Ring, C., Drayson, M., Bosch, J., Inskip, A., Long, J., Pulsford, D., Burns, V. (2010). The effects of vaccine timing on the efficacy of an acute eccentric exercise intervention on the immune response to an influenza vaccine in young adu. Brain, Behavior, and Immunity, 24(2), 236-242. [More Information]
  • Bosch, J., de Geus, E., Carroll, D., Goedhart, A., Anane, L., Veldhuizen van Zanten, J., Helmerhorst, E., Edwards, K. (2009). A General Enhancement of Autonomic and Cortisol Responses During Social Evaluative Threat. Psychosomatic Medicine, 71(8), 877-885. [More Information]
  • Aldred, S., Rohalu, M., Edwards, K., Burns, V. (2009). Altered DHEA and DHEAS response to exercise in healthy older adults. Journal of Aging and Physical Activity, 17(1), 77-88.
  • Anane, L., Edwards, K., Burns, V., Drayson, M., Riddell, N., Veldhuijzen Van Zanten, J., Wallace, G., Mills, P., Bosch, J. (2009). Mobilization of γδ T lymphocytes in response to psychological stress, exercise, and β-agonist infusion. Brain, Behavior, and Immunity, 23(6), 823-829. [More Information]
  • Burns, V., Edwards, K., Ring, C., Drayson, M., Carroll, D. (2008). Complement Cascade Activation After an Acute Psychological Stress Task. Psychosomatic Medicine, 70(4), 387-396.
  • Edwards, K., Mills, P. (2008). Effects of estrogen versus estrogen and progesterone on cortisol and interleukin-. Maturitas, 61(4), 330-333. [More Information]
  • Edwards, K., Burns, V., Adkins, A., Carroll, D., Drayson, M., Ring, C. (2008). Meningococcal A Vaccination Response is Enhanced by Acute Stress in Men. Psychosomatic Medicine, 70(2), 147-151. [More Information]
  • O’Donoghue, P., Mayes, A., Edwards, K., Garland, J. (2008). Performance Norms for British National Super League Netball. International Journal of Sports Science and Coaching, 3(4), 501-511.
  • Edwards, K., Burns, V., Allen, L., McPhee, J., Bosch, J., Carroll, D., Drayson, M., Ring, C. (2007). Eccentric exercise as an adjuvant to influenza vaccination in humans. Brain, Behavior, and Immunity, 21(2), 209-217. [More Information]
  • Edwards, K. (2007). Reduction of Plasma sCD40L and Stimulated MIP-1-Alpha Production by in vivo Beta-Adrenergic Stimulation. Neuroimmunomodulation, 14(5), 266-271. [More Information]
  • Edwards, K., Burns, V., Carroll, D., Drayson, M., Ring, C. (2007). The Acute Stress-Induced Immunoenhancement Hypothesis. Exercise and Sport Sciences Reviews, 35(3), 150-155. [More Information]
  • Edwards, K., Ziegler, M., Mills, P. (2007). The potential anti-inflammatory benefits of improving physical fitness in hypertension. Journal of Hypertension, 25(8), 1533-1542. [More Information]
  • Edwards, K., Burns, V., Reynolds, T., Carroll, D., Drayson, M., Ring, C. (2006). Acute stress exposure prior to inXuenza vaccination enhances antibody response in women. Brain, Behavior, and Immunity, 20(2), 159-168. [More Information]
  • Edwards, K., Burns, V., Ring, C., Carroll, D. (2006). Individual differences in the interleukin-6 response to maximal and submaximal exercise tasks. Journal of Sports Sciences, 24(8), 855-862. [More Information]
  • Edwards, K., Burns, V., Ring, C., Carroll, D. (2006). Sex differences in the interleukin-6 response to acute psychological stress. Biological Psychology, 71(3), 236-239. [More Information]
  • Veldhuijzen Van Zanten, J., Ring, C., Burns, V., Edwards, K., Drayson, M., Carroll, D. (2004). Mental stress-induced hemoconcentration: Sex differences and mechanisms. Psychophysiology, 41(4), 541-551. [More Information]

Reference Works

  • Burns, V., Phillips, A., Edwards, K. (2007). Vaccination. In George Fink (editor-in-chief) (Eds.), Encyclopedia of Stress (2nd edition), Vol. 3. (pp. 813-817). Amsterdam: Elsevier.

2014

  • Edwards, K., Kamat, R., Tomfohr, L., Ancoli-Israel, S., Dimsdale, J. (2014). Obstructive sleep apnea and neurocognitive performance: the role of cortisol. Sleep Medicine, 15(1), 27-32. [More Information]
  • Turner, J., Campbell, J., Edwards, K., Howarth, L., Pawelec, G., Aldred, S., Moss, P., Drayson, M., Burns, V., Bosch, J. (2014). Rudimentary signs of immunosenescence in cytomegalovirus-seropositive healthy young adults. Age, 36(1), 287-297. [More Information]
  • Pascoe, A., Fiatarone Singh, M., Edwards, K. (2014). The effects of exercise on vaccination responses: A review of chronic and acute exercise interventions in humans. Brain, Behavior, and Immunity, 39, 33-41. [More Information]

2013

  • Edwards, K., Booy, R. (2013). Effects of exercise on vaccine-induced immune responses. Human Vaccines & Immunotherapeutics, 9(4), 907-910. [More Information]
  • Edwards, K., Mills, P. (2013). Physical activity, stress, and immune function. In Panteleimon Ekkekakis (Eds.), Routledge Handbook of Physical Activity and Mental Health, (pp. 342-355). Abingdon: Routledge.

2012

  • Edwards, K., Pung, M., Tomfohr, L., Ziegler, M., Campbell, J., Drayson, M., Mills, P. (2012). Acute exercise enhancement of pneumococcal vaccination response: A randomised controlled trial of weaker and stronger immune response. Vaccine, 30(45), 6389-6395. [More Information]
  • Wilson, K., Tomfohr, L., Edwards, K., Knott, C., Hong, S., Redwine, L., Calfas, K., Rock, C., von Kanel, R., Mills, P. (2012). Effects of aerobic fitness and adiposity on coagulation biomarkers in men vs. women with elevated blood pressure. European Journal of Cardiovascular Medicine, 2(2), 122-128. [More Information]
  • Sadja, J., Tomfohr, L., Jimenez, J., Edwards, K., Rock, C., Calfas, K., Mills, P. (2012). Higher Physical Fatigue Predicts Adherence to a 12-Week Exercise Intervention in Women With Elevated Blood Pressure. Health Psychology, 31(2), 156-163. [More Information]
  • Tomfohr, L., Edwards, K., Dimsdale, J. (2012). Is obstructive sleep apnea associated with cortisol levels? A systematic review of the research evidence. Sleep Medicine Reviews, 16(3), 243-249. [More Information]
  • Tomfohr, L., Pung, M., Edwards, K., Dimsdale, J. (2012). Racial differences in sleep architecture: The role of ethnic discrimination. Biological Psychology, 89(1), 34-38. [More Information]

2011

  • Edwards, K., Campbell, J. (2011). Acute Exercise as an Adjuvant to Influenza Vaccination. American Journal of Lifestyle Medicine, 5(6), 512-517. [More Information]
  • Edwards, K., Wilson, K., Sadja, J., Ziegler, M., Mills, P. (2011). Effects on blood pressure and autonomic nervous system function of a 12-week exercise or exercise plus DASH-diet intervention in individuals with elevated blood pressure. Acta Physiologica, 203, 343-350.
  • Edwards, K., Mills, P. (2011). Interaktionen zwischen dem endokrinen, dem zentralnervösen und dem Immunsystem. In Ulrike Ehlert, Roland von Kanel (Eds.), Psychoendokrinologie und Psychoimmunologie, (pp. 111-127). Berlin, Germany: Springer-Verlag.
  • Edwards, K., Tomfohr, L., Mills, P., Bosch, J., Ancoli-Israel, S., Loredo, J., Dimsdale, J. (2011). Macrophage Migratory Inhibitory Factor (MIF) May Be a Key Factor in Inflammation in Obstructive Sleep Apnea. Sleep, 34(2), 161-163.
  • Shoucri, B., Edwards, K., Schmid-Schonbein, G., Mills, P. (2011). Plasma-stimulated pseudopod formation is increased in patients with elevated blood pressure. Hypertension Research, 34(6), 787-789. [More Information]

2010

  • Edwards, K., Bosch, J., Engeland, C., Cacioppo, J., Marucha, P. (2010). Elevated Macrophage Migration Inhibitory Factor (MIF) is associated with depressive symptoms, blunted cortisol reactivity to acute stress, and lowered morning cortisol. Brain, Behavior, and Immunity, 24(7), 1202-1208. [More Information]
  • Edwards, K., Campbell, J., Ring, C., Drayson, M., Bosch, J., Downes, C., Long, J., Lumb, J., Merry, A., Paine, N., et al (2010). Exercise intensity does not influence the efficacy of eccentric exercise as a behavioural adjuvant to vaccination. Brain, Behavior, and Immunity, 24(4), 623-630. [More Information]
  • Edwards, K., Sheu, B., Hong, S., Penn, A., Schmid-Schonbein, G., Mills, P. (2010). Leukocyte membrane bleb and pseudopod formation in hypertension. Journal of Human Hypertension, 24(10), 684-686.
  • Anane, L., Edwards, K., Burns, V., Veldhuijzen Van Zanten, J., Drayson, M., Bosch, J. (2010). Phenotypic characterization of cd T cells mobilized in response to acute psychological stress. Brain, Behavior, and Immunity, 24(4), 608-614. [More Information]
  • Campbell, J., Edwards, K., Ring, C., Drayson, M., Bosch, J., Inskip, A., Long, J., Pulsford, D., Burns, V. (2010). The effects of vaccine timing on the efficacy of an acute eccentric exercise intervention on the immune response to an influenza vaccine in young adu. Brain, Behavior, and Immunity, 24(2), 236-242. [More Information]

2009

  • Bosch, J., de Geus, E., Carroll, D., Goedhart, A., Anane, L., Veldhuizen van Zanten, J., Helmerhorst, E., Edwards, K. (2009). A General Enhancement of Autonomic and Cortisol Responses During Social Evaluative Threat. Psychosomatic Medicine, 71(8), 877-885. [More Information]
  • Aldred, S., Rohalu, M., Edwards, K., Burns, V. (2009). Altered DHEA and DHEAS response to exercise in healthy older adults. Journal of Aging and Physical Activity, 17(1), 77-88.
  • Anane, L., Edwards, K., Burns, V., Drayson, M., Riddell, N., Veldhuijzen Van Zanten, J., Wallace, G., Mills, P., Bosch, J. (2009). Mobilization of γδ T lymphocytes in response to psychological stress, exercise, and β-agonist infusion. Brain, Behavior, and Immunity, 23(6), 823-829. [More Information]

2008

  • Burns, V., Edwards, K., Ring, C., Drayson, M., Carroll, D. (2008). Complement Cascade Activation After an Acute Psychological Stress Task. Psychosomatic Medicine, 70(4), 387-396.
  • Edwards, K., Mills, P. (2008). Effects of estrogen versus estrogen and progesterone on cortisol and interleukin-. Maturitas, 61(4), 330-333. [More Information]
  • Edwards, K., Burns, V., Adkins, A., Carroll, D., Drayson, M., Ring, C. (2008). Meningococcal A Vaccination Response is Enhanced by Acute Stress in Men. Psychosomatic Medicine, 70(2), 147-151. [More Information]
  • O’Donoghue, P., Mayes, A., Edwards, K., Garland, J. (2008). Performance Norms for British National Super League Netball. International Journal of Sports Science and Coaching, 3(4), 501-511.

2007

  • Edwards, K., Burns, V., Allen, L., McPhee, J., Bosch, J., Carroll, D., Drayson, M., Ring, C. (2007). Eccentric exercise as an adjuvant to influenza vaccination in humans. Brain, Behavior, and Immunity, 21(2), 209-217. [More Information]
  • Edwards, K. (2007). Reduction of Plasma sCD40L and Stimulated MIP-1-Alpha Production by in vivo Beta-Adrenergic Stimulation. Neuroimmunomodulation, 14(5), 266-271. [More Information]
  • Edwards, K., Burns, V., Carroll, D., Drayson, M., Ring, C. (2007). The Acute Stress-Induced Immunoenhancement Hypothesis. Exercise and Sport Sciences Reviews, 35(3), 150-155. [More Information]
  • Edwards, K., Ziegler, M., Mills, P. (2007). The potential anti-inflammatory benefits of improving physical fitness in hypertension. Journal of Hypertension, 25(8), 1533-1542. [More Information]
  • Burns, V., Phillips, A., Edwards, K. (2007). Vaccination. In George Fink (Eds.), Encyclopedia of Stress, (pp. 813-817). UK: Academic Press Elsevier.
  • Burns, V., Phillips, A., Edwards, K. (2007). Vaccination. In George Fink (editor-in-chief) (Eds.), Encyclopedia of Stress (2nd edition), Vol. 3. (pp. 813-817). Amsterdam: Elsevier.

2006

  • Edwards, K., Burns, V., Reynolds, T., Carroll, D., Drayson, M., Ring, C. (2006). Acute stress exposure prior to inXuenza vaccination enhances antibody response in women. Brain, Behavior, and Immunity, 20(2), 159-168. [More Information]
  • Edwards, K., Burns, V., Ring, C., Carroll, D. (2006). Individual differences in the interleukin-6 response to maximal and submaximal exercise tasks. Journal of Sports Sciences, 24(8), 855-862. [More Information]
  • Edwards, K., Burns, V., Ring, C., Carroll, D. (2006). Sex differences in the interleukin-6 response to acute psychological stress. Biological Psychology, 71(3), 236-239. [More Information]

2004

  • Veldhuijzen Van Zanten, J., Ring, C., Burns, V., Edwards, K., Drayson, M., Carroll, D. (2004). Mental stress-induced hemoconcentration: Sex differences and mechanisms. Psychophysiology, 41(4), 541-551. [More Information]

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