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Dr Lining Ju

Conjoint Lecturer
Heart Research Institute

Member of the Charles Perkins Centre


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Selected grants

2018

  • Towards a novel 'mechanomedicine' against the sticky clot problem of diabetes by targeting oxidoreductase ERp5; Chiu J, Ju L; Charles Perkins Centre/Early-Mid Career Researcher Seed Funding grant.
  • Develop high-throughput single cell analysis for diabetic platelet prothrombotic phenotype; Ju L; National Heart Foundation of Australia/Collaboration and Exchange Award.

2017

  • Deep profiling of platelet hyperactive phenotypes in diabetes; Ju L; National Heart Foundation of Australia/Postdoctoral Fellowships (Biomedical, Clinical, Public Health, Health Services).
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Selected publications

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Book Chapters

  • Ju, L., Chen, Y., Rushdi, M., Chen, W., Zhu, C. (2017). Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. In Cosima T Baldari, Michael L Dustin (Eds.), The Immune Synapse: Methods and Protocols, (pp. 231-258). New York: Springer. [More Information]

Journals

  • Ren, W., Wen, S., Tawfik, S., Su, Q., Lin, G., Ju, L., Ford, M., Ghodke, H., Van Oijen, A., Jin, D. (2018). Anisotropic functionalization of upconversion nanoparticles. Chemical Science, 9(18), 4352-4358. [More Information]
  • Xu, X., Wang, Y., Adili, R., Ju, L., Spring, C., Jin, J., Yang, H., Neves, M., Chen, P., Yang, Y., Jackson, S., et al (2018). Apolipoprotein A-IV binds ?IIb?3 integrin and inhibits thrombosis. Nature Communications, 9(1), 1-18. [More Information]
  • Butera, D., Passam, F., Ju, L., Cook, K., Woon, H., Aponte-Santamaria, C., Gardiner, E., Davis, A., Murphy, D., Bronowska, A., Jackson, S., Hogg, P., et al (2018). Autoregulation of von Willebrand factor function by a disulfide bond switch. Science Advances, 4(2), 1-12. [More Information]
  • Ju, L., McFadyen, J., Al-Daher, S., Alwis, I., Chen, Y., Tonnesen, L., Maiocchi, S., Coulter, B., Calkin, A., Felner, E., Yuan, Y., Schoenwaelder, S., Jackson, S., et al (2018). Compression force sensing regulates integrin αiIbβ3adhesive function on diabetic platelets. Nature Communications, 9(1), 1-16. [More Information]
  • Passam, F., Chiu, J., Ju, L., Pijning, A., Jahan, Z., Mor-Cohen, R., Yeheskel, A., Kolsek, K., Tharichen, L., Aponte-Santamaria, C., Hogg, P., et al (2018). Mechano-redox control of integrin de-adhesion. eLife, 7, 1-22. [More Information]
  • Ju, L., Zhu, C. (2017). Benchmarks of Biomembrane Force Probe Spring Constant Models. Biophysical Journal, 113(12), 2842-2845. [More Information]
  • Ju, L., Chen, Y., Li, K., Yuan, Z., Liu, B., Jackson, S., Zhu, C. (2017). Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species. Scientific Reports, 7(14185), 1-12. [More Information]
  • Chen, Y., Ju, L., Rushdi, M., Ge, C., Zhu, C. (2017). Receptor-mediated cell mechanosensing. Molecular Biology of the Cell, 28(23), 3134-3155. [More Information]
  • Ju, L., Chen, Z., Xue, L., Du, X., Zhu, W. (2016). Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals. eLife, 5, 1-24. [More Information]
  • Chen, Y., Liu, B., Ju, L., Hong, J., Ji, Q., Chen, W., Zhu, C. (2015). Fluorescence biomembrane force probe: Concurrent quantitation of receptor-ligand kinetics and binding-induced intracellular signaling on a single cell. Journal of Visualized Experiments, August 2015(102), 1-13. [More Information]
  • Ju, L., Lou, J., Chen, Y., Li, Z., Zhu, C. (2015). Force-Induced Unfolding of Leucine-Rich Repeats of Glycoprotein Ibalpha Strengthens Ligand Interaction. Biophysical Journal, 109(9), 1781-1784. [More Information]
  • Samson, A., Ju, L., Ah KIm, H., Zhang, S., Maclean, J., Sturgeon, S., Sobey, C., Jackson, S., Schoenwaelder, S. (2015). MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents. Scientific Reports, 5, 1-11. [More Information]

2018

  • Ren, W., Wen, S., Tawfik, S., Su, Q., Lin, G., Ju, L., Ford, M., Ghodke, H., Van Oijen, A., Jin, D. (2018). Anisotropic functionalization of upconversion nanoparticles. Chemical Science, 9(18), 4352-4358. [More Information]
  • Xu, X., Wang, Y., Adili, R., Ju, L., Spring, C., Jin, J., Yang, H., Neves, M., Chen, P., Yang, Y., Jackson, S., et al (2018). Apolipoprotein A-IV binds ?IIb?3 integrin and inhibits thrombosis. Nature Communications, 9(1), 1-18. [More Information]
  • Butera, D., Passam, F., Ju, L., Cook, K., Woon, H., Aponte-Santamaria, C., Gardiner, E., Davis, A., Murphy, D., Bronowska, A., Jackson, S., Hogg, P., et al (2018). Autoregulation of von Willebrand factor function by a disulfide bond switch. Science Advances, 4(2), 1-12. [More Information]
  • Ju, L., McFadyen, J., Al-Daher, S., Alwis, I., Chen, Y., Tonnesen, L., Maiocchi, S., Coulter, B., Calkin, A., Felner, E., Yuan, Y., Schoenwaelder, S., Jackson, S., et al (2018). Compression force sensing regulates integrin αiIbβ3adhesive function on diabetic platelets. Nature Communications, 9(1), 1-16. [More Information]
  • Passam, F., Chiu, J., Ju, L., Pijning, A., Jahan, Z., Mor-Cohen, R., Yeheskel, A., Kolsek, K., Tharichen, L., Aponte-Santamaria, C., Hogg, P., et al (2018). Mechano-redox control of integrin de-adhesion. eLife, 7, 1-22. [More Information]

2017

  • Ju, L., Zhu, C. (2017). Benchmarks of Biomembrane Force Probe Spring Constant Models. Biophysical Journal, 113(12), 2842-2845. [More Information]
  • Ju, L., Chen, Y., Li, K., Yuan, Z., Liu, B., Jackson, S., Zhu, C. (2017). Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species. Scientific Reports, 7(14185), 1-12. [More Information]
  • Chen, Y., Ju, L., Rushdi, M., Ge, C., Zhu, C. (2017). Receptor-mediated cell mechanosensing. Molecular Biology of the Cell, 28(23), 3134-3155. [More Information]
  • Ju, L., Chen, Y., Rushdi, M., Chen, W., Zhu, C. (2017). Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. In Cosima T Baldari, Michael L Dustin (Eds.), The Immune Synapse: Methods and Protocols, (pp. 231-258). New York: Springer. [More Information]

2016

  • Ju, L., Chen, Z., Xue, L., Du, X., Zhu, W. (2016). Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals. eLife, 5, 1-24. [More Information]

2015

  • Chen, Y., Liu, B., Ju, L., Hong, J., Ji, Q., Chen, W., Zhu, C. (2015). Fluorescence biomembrane force probe: Concurrent quantitation of receptor-ligand kinetics and binding-induced intracellular signaling on a single cell. Journal of Visualized Experiments, August 2015(102), 1-13. [More Information]
  • Ju, L., Lou, J., Chen, Y., Li, Z., Zhu, C. (2015). Force-Induced Unfolding of Leucine-Rich Repeats of Glycoprotein Ibalpha Strengthens Ligand Interaction. Biophysical Journal, 109(9), 1781-1784. [More Information]
  • Samson, A., Ju, L., Ah KIm, H., Zhang, S., Maclean, J., Sturgeon, S., Sobey, C., Jackson, S., Schoenwaelder, S. (2015). MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents. Scientific Reports, 5, 1-11. [More Information]
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