Dr Kimberley Beaumont

Honorary Associate
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology

Telephone +61 2 9565 6258

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Biographical details

Dr Beaumont received her PhD from the University of Queensland in 2009. In her previous work she published several high impact papers on the function of Melanocortin-1 Receptor variants, which are associated with red hair, fair skin and skin cancer risk. In 2011 she moved to the Centenary Institute and is now focused on investigating the mechanisms underlying melanoma progression. Together with Assoc Prof Nikolas Haass, Kimberley is currently leading the Experimental Melanoma Therapy sub-group within the Immune Imaging Program (headed by Prof Wolfgang Weninger).

Research interests

Dr Beaumont's research interests cover many aspects of melanoma biology, with the aim of discovering new therapeutic strategies. In her studies she utilizes a 3D melanoma spheroid model, which better mimics the tumour microenvironment, as well as animal models. Dr Beaumont specialises in live, confocal and multiphoton miscroscopy, and uses a novel fluorescent cell cycle indicator (FUCCI) that allows visualization of cell cycle dynamics in real-time.

PhD and master's project opportunities

Selected grants

2014

  • Rab27a as a novel therapeutic target: Investigating the role of Rab27a in melanoma growth and invasion.; Beaumont K; Cancer Institute New South Wales/Early Career Development Fellowship.

2013

  • The role of Rab27a and Rab5a in melanoma phenotype switching; Beaumont K; Cancer Australia/Priority Driven Collaborative Cancer Research Scheme.
  • Effect of three-dimensional tumour organisation on the sensitivity of individual melanoma cells to endoplasmic reticulum stress; Haass N, Beaumont K, Weninger W; Cancer Council New South Wales/Research Project Grants.

Selected publications

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Journals

  • Beaumont, K., Kumaran - Mohana, N., Haass, N. (2014). Modeling Melanoma In Vitro and In Vivo. Healthcare, 2, 27-46. [More Information]
  • Beaumont, K., Smit, D., Liu, Y., Chai, E., Patel, M., Millhauser, G., Smith, J., Alewood, P., Sturm, R. (2013). Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. Pigment Cell and Melanoma Research, 25(3), 370-374. [More Information]
  • Beaumont, K., Munoz, M., Weninger, W. (2013). Mesenchymal Cells Hold the Key to Immune Cell Recruitment to and Migration within Melanoma. The Journal of Investigative Dermatology, 133(9), 2138-2140. [More Information]
  • Beaumont, K., Wong, S., Ainger, S., Liu, Y., Patel, M., Millhauser, G., Smith, J., Alewood, P., Leonard, J., Sturm, R. (2011). Melanocortin MC1 receptor in human genetics and model systems. European Journal of Pharmacology, 660(1), 103-110. [More Information]
  • Beaumont, K., Hamilton, N., Moores, M., Brown, D., Ohbayashi, N., Cairncross, O., Cook, A., Smith, A., Misaki, R., Fukuda, M., et al (2011). The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. Traffic (Malden), 12(5), 627-643. [More Information]
  • Smith, A., Beaumont, K., Smit, D., Thurber, A., Cook, A., Boyle, G., Parsons, P., Sturm, R., Muscat, G. (2009). PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells. The International Journal of Biochemistry and Cell Biology, 41(4), 844-852. [More Information]
  • Beaumont, K., Shekar, S., Cook, A., Duffy, D., Sturm, R. (2008). Red hair is the null phenotype of MC1R. Human Mutation, 29(8), E88-E94. [More Information]

2014

  • Beaumont, K., Kumaran - Mohana, N., Haass, N. (2014). Modeling Melanoma In Vitro and In Vivo. Healthcare, 2, 27-46. [More Information]

2013

  • Beaumont, K., Smit, D., Liu, Y., Chai, E., Patel, M., Millhauser, G., Smith, J., Alewood, P., Sturm, R. (2013). Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. Pigment Cell and Melanoma Research, 25(3), 370-374. [More Information]
  • Beaumont, K., Munoz, M., Weninger, W. (2013). Mesenchymal Cells Hold the Key to Immune Cell Recruitment to and Migration within Melanoma. The Journal of Investigative Dermatology, 133(9), 2138-2140. [More Information]

2011

  • Beaumont, K., Wong, S., Ainger, S., Liu, Y., Patel, M., Millhauser, G., Smith, J., Alewood, P., Leonard, J., Sturm, R. (2011). Melanocortin MC1 receptor in human genetics and model systems. European Journal of Pharmacology, 660(1), 103-110. [More Information]
  • Beaumont, K., Hamilton, N., Moores, M., Brown, D., Ohbayashi, N., Cairncross, O., Cook, A., Smith, A., Misaki, R., Fukuda, M., et al (2011). The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. Traffic (Malden), 12(5), 627-643. [More Information]

2009

  • Smith, A., Beaumont, K., Smit, D., Thurber, A., Cook, A., Boyle, G., Parsons, P., Sturm, R., Muscat, G. (2009). PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells. The International Journal of Biochemistry and Cell Biology, 41(4), 844-852. [More Information]

2008

  • Beaumont, K., Shekar, S., Cook, A., Duffy, D., Sturm, R. (2008). Red hair is the null phenotype of MC1R. Human Mutation, 29(8), E88-E94. [More Information]

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