Specialised facilities available to staff and students of the Adrien Albert Laboratory
Two purpose built rooms and equipment to study in mice the effects of new chemical entities on anxiety (elevated plus maze) and memory (Morris water maze).
Computational Chemistry and Molecular modelling
IBM and Silicon Graphics workstations running AMPAC, AMSOL, Catalyst, Gaussian 94, Molpro, and MOPAC for the computer aided design of new chemical entities. Macintosh and Pentium computers running Chem-X, Chem 3D, Macromodel and Spartan. Access to supercomputing (Silicon Graphics Power Challenge) at the NSW Centre for Parallel Computing.
Facilities for PCR, site-directed mutagenesis and preparation of chimeric cloned receptors and transporters. Access to sequencing via the The Sydney University Prince Alfred Macromolecular Analysis Centre (SUPAMAC).
Facilities for the study of neurotransmitter binding, uptake and release in preparations of nervous tissue. The laboratory has access to human postmortem brain issue through the NISAD Centre for Collaborative Human Brain Research at the University of Sydney.
Equipment for the study of drug action on tissue slice preparations (cortical wedges, hippocampal slices), and on cloned receptors and transporters expressed in Xenopus oocytes.
Two well equipped laboratories for preparative organic chemistry.
Varian Gemini 300 MHz NMR spectrometer.
Hewlett Packard HP5890 gas chromatograph/mass spectrometer.