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Biology of Dipeptidyl Peptidase IV and related proteins

Research projects centre on mouse models of liver disease and obesity and on the delineation of inhibitors, substrates, biochemistry and in vivo expression and function of the Dipep more...

Supervisor(s): Gorrell, Mark (Associate Professor)

Molecular investigations of receptors involved in neurological disorders

The Laboratory of Molecular Neuroscience investigates molecular regulation and drug interactions that occur in receptors associated with neurological diseases. more...

Supervisor(s): Holsinger, Damian (Dr)

Post-translational modifications in bacterial proteins

This project will identify novel proteins that are post-translationally modified in bacterial pathogens and the role of such modification in virulence. more...

Supervisor(s): Cordwell, Stuart (Professor)

How can animals cope with climatic variability?

Research to discover how the environment affects animal function, and if and how animals can compensate for environmental variability. more...

Supervisor(s): Seebacher, Frank (Professor)

Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

Inhertied and acquired platelet function defects

Bleeding defects in Australian patients and families will be characterised using genomic and proteomic analysis more...

Supervisor(s): Ward, Chris (Professor)

Kinetic Characterization and Mapping for Whole-body Molecular Image Retrieval

In vivo kinetic behaviour characterization and dynamic holistic mapping for efficient dual-modality whole-body molecular imaging data retrieval. more...

Supervisor(s): Feng, David (Professor), Cai, Tom Weidong (Associate Professor)

An investigation into the mechanisms of immune evasion in metastatic melanoma patients treated with molecular or immune checkpoint inhibitors.

The aim of this project is to characterise the immune reaction and prevalence of immune inhibitory mechanisms present in metastatic melanoma patient tumours whilst on immune checkpo more...

Supervisor(s): Scolyer, Richard (Professor), Long, Georgina (Professor)

Interactions between porcine ligands and the human lymphocyte activating receptor NKG2D

Role of NKG2D in the human cellular immune response against porcine xenotransplants. more...

Supervisor(s): Sharland, Alexandra (Dr)

Dendritic cells and control of T cell immune responses

DCs are unique antigen-presenting cells that can initiate (prime) CD4 T cell responses, as well as controlling the progression and subsequent reduction of the immune response, devel more...

Supervisor(s): Fazekas, Barbara (Professor)