Professor Trevor Hambley
People_

Professor Trevor Hambley

FAA; BSc UWA; PhD Adelaide
Emeritus Professor of Chemistry
Phone
61 2 9036 9153
Fax
61 2 9351 3329
Address
F11 - Chemistry Building
The University of Sydney
Websites
Professor Trevor Hambley

Trevor Hambley is Emeritus Professor of Chemistry at the University of Sydney's School of Chemistry.

His research interests are in the area of medicinal inorganic chemistry with an emphasis on platinum anticancer drugs, hypoxia selective cobalt complexes, and metal based anti-inflammatory compounds. He has published 4 books, 24 reviews, and more than 470 refereed journal papers.

Professor Hambley was the recipient of the Edgeworth David Medal for contributions to Science by an Australian under the age of 35 and has received the “Supervisor of the Year” award at the University of Sydney in 1997 and an Excellence in Teaching Award for Postgraduate Supervision in 1998.

  • Medicinal inorganic chemistry, in particular, Pt anticancer drugs
  • Targetted delivery of metal based anticancer agents
  • Investigating the relationship between the reduction potentials of Pt(IV) complexes and their biological activity
  • Investigating methods for controlling the physical and biological properties of platinum(IV) complexes
  • Development of synchrotron radiation based methods for the in situ determination of oxidation states of platinum in biological environments and for reliably determining platinum distributions in these environments
  • Investigation of cobalt complexes as delivery agents for anticancer agents
  • Investigating and optimizing anticancer drug penetration in solid tumours and tumour models.
  • Please see our home page for detailed coverage of our research activities.

Please see our home page for detailed coverage of our research activities at http://sydney.edu.au/science/chemistry/~hamble_t/

  • Edgeworth David Medal for contributions to Science by an Australian under the age of 35
  • “Supervisor of the Year” award at the University of Sydney in 1997
  • Excellence in Teaching Award for Postgraduate Supervision in 1998.
Project titleResearch student
How do biologically inert probes enter cancer cells?Bronte CARROLL

Selected publications

Publications

Books

  • Comba, P., Hambley, T., Martin, B. (2009). Molecular Modeling of Inorganic Compounds: Third, Completely Revised and Enlarged Edition. Federal Republic of Germany: Wiley - V C H Verlag GmbH & Co. KGaA.
  • Hambley, T., Comba, P. (2001). Molecular Modeling of Inorganic Compounds. Germany: Wiley - V C H Verlag GmbH & Co. KGaA.

Book Chapters

  • Klein, A., Hambley, T. (2014). Platinum-Based Anticancer Agents. In Tim Storr (Eds.), Ligand Design in Medicinal Inorganic Chemistry, (pp. 9-45). Chichester, United Kingdom: John Wiley & Sons. [More Information]
  • Norman, J., Hambley, T. (2011). Targeting strategies for metal-based therapeutics. In Professor Enzo Alessio (Eds.), Bioinorganic Medicinal Chemistry, (pp. 49-78). Germany: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]
  • Zhang, J., Whan, R., Hambley, T. (2009). Platinum anticancer drugs, chemical biology of. In Natanya Civjan (Eds.), Wiley Encyclopaedia of Chemical Biology, (pp. 721-730). Hoboken, New Jersey, USA: John Wiley & Sons.

Journals

  • Hambley, T., Rae, I. (2022). Hans Charles Freeman 1929-2008. Historical Records of Australian Science, 33(2), 180-190. [More Information]
  • Lo, A., Bryce, N., Klein, A., Todd, M., Hambley, T. (2021). Novel polyamide amidine anthraquinone platinum(II) complexes: cytotoxicity, cellular accumulation, and fluorescence distributions in 2D and 3D cell culture models. Journal of Biological Inorganic Chemistry, 26, 217-233. [More Information]
  • Lo, A., Chen, J., Murray, V., Todd, M., Hambley, T. (2021). Platinum binding preferences dominate the binding of novel polyamide amidine anthraquinone platinum(ii) complexes to DNA. Dalton Transactions, 50(48), 17945-17952. [More Information]

Conferences

  • Hambley, T. (2009). Improving anticancer drug penetration in solid tumours (Invited lecture). 14th International Conference on Biological Inorganic Chemistry, N/A: N/A.
  • Hambley, T., Gui, X. (2009). Investigations into the electrochemical properties of Pt(IV) agents. 14th International Conference on Bioinorganic Chemistry.
  • Zhang, J., Bryce, N., Hambley, T. (2009). The penetration and accumulation of anti-tumour platinum(II) complexes in spheroid tumour models. 14th International Conference on Biological Inorganic Chemistry, N/A: N/A.

Patents

  • Hawkett, B., Bryce, N., Jain, N., Hambley, T., Pham, B. (2020). Method of Treating Cancer. Patent No. 10376589, 10376589, 2012245080, 2699233, 2833413, 6038881, 616780, TR201312152, 2012245080, 2699233, 6038881, 616780, TR201312152. , , Austria, Belgium, Canada, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom, Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom.
  • Hawkett, B., Hambley, T., Bryce, N., Pham, B., Jain, N. (2012). A method for the treatment of a solid tumour. Patent No. CA2833413 A1, CA2833413 A1, WO2012142669 A1. , Canada, Canada.

2022

  • Hambley, T., Rae, I. (2022). Hans Charles Freeman 1929-2008. Historical Records of Australian Science, 33(2), 180-190. [More Information]

2021

  • Lo, A., Bryce, N., Klein, A., Todd, M., Hambley, T. (2021). Novel polyamide amidine anthraquinone platinum(II) complexes: cytotoxicity, cellular accumulation, and fluorescence distributions in 2D and 3D cell culture models. Journal of Biological Inorganic Chemistry, 26, 217-233. [More Information]
  • Lo, A., Chen, J., Murray, V., Todd, M., Hambley, T. (2021). Platinum binding preferences dominate the binding of novel polyamide amidine anthraquinone platinum(ii) complexes to DNA. Dalton Transactions, 50(48), 17945-17952. [More Information]
  • Glenister, A., Chen, C., Paterson, D., Renfrew, A., Simone, M., Hambley, T. (2021). Warburg Effect Targeting Co(III) Cytotoxin Chaperone Complexes. Journal of Medicinal Chemistry, 64(5), 2678-2690. [More Information]

2020

  • Hawkett, B., Bryce, N., Jain, N., Hambley, T., Pham, B. (2020). Method of Treating Cancer. Patent No. 10376589, 10376589, 2012245080, 2699233, 2833413, 6038881, 616780, TR201312152, 2012245080, 2699233, 6038881, 616780, TR201312152. , , Austria, Belgium, Canada, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom, Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom.
  • Chen, C., Gui, X., Kappen, P., Renfrew, A., Hambley, T. (2020). The effect of charge on the uptake and resistance to reduction of platinum(IV) complexes in human serum and whole blood models. Metallomics, 12(10), 1599-1615. [More Information]
  • Chen, C., Kappen, P., Gibson, D., Hambley, T. (2020). trans-Platinum(iv) pro-drugs that exhibit unusual resistance to reduction by endogenous reductants and blood serum but are rapidly activated inside cells:1H NMR and XANES spectroscopy study. Dalton Transactions, 49(23), 7722-7736. [More Information]

2019

  • Glenister, A., Simone, M., Hambley, T. (2019). A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake. PloS One, 14(7), 1-16. [More Information]
  • Hambley, T. (2019). Element 78 - Platinum. Australian Journal of Chemistry, 72(9), 649-651. [More Information]
  • Di Marco, L., Zhang, J., Doan, J., Kim, B., Yamamoto, N., Bryce, N., Hambley, T. (2019). Modulating the cellular uptake of fluorescently tagged substrates of prostate-specific antigen before and after enzymatic activation. Bioconjugate Chemistry, 30(1), 124-133. [More Information]

2018

  • Kolanowski, J., Dawson, L., Mitchell, L., Lim, Z., Graziotto, M., Filipek, W., Hambley, T., New, E. (2018). A fluorescent probe for investigating metabolic stability of active transplatin analogues. Sensors and Actuators B: Chemical, 255(Part 3), 2721-2724. [More Information]
  • Carney, I., Kolanowski, J., Lim, Z., Chekroun, B., Torrisi, A., Hambley, T., New, E. (2018). A ratiometric iron probe enables investigation of iron distribution within tumour spheroids. Metallomics, 10(4), 553-556. [More Information]
  • Renfrew, A., O'Neill, E., Hambley, T., New, E. (2018). Harnessing the properties of cobalt coordination complexes for biological application. Coordination Chemistry Reviews, 375, 221-233. [More Information]

2017

  • Akerfeldt, M., Tran, C., Shen, C., Hambley, T., New, E. (2017). Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells. Journal of Biological Inorganic Chemistry, 22(5), 765-774. [More Information]
  • Glenister, A., Chen, C., Tondl, E., Paterson, D., Hambley, T., Renfrew, A. (2017). Targeting curcumin to specific tumour cell environments: the influence of ancillary ligands. Metallomics, 9(6), 699-705. [More Information]
  • Green, B., Renfrew, A., Glenister, A., Turner, P., Hambley, T. (2017). The influence of the ancillary ligand on the potential of cobalt(III) complexes to act as chaperones for hydroxamic acid-based drugs. Dalton Transactions, 46(45), 15897-15907. [More Information]

2016

  • Puranik, R., Bao, B., Bonin, A., Kaur, R., Weder, J., Casbolt, L., Hambley, T., Lay, P., Barter, P., Rye, K. (2016). A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo. Cell and Bioscience, 6(1), 1-7. [More Information]
  • Shen, C., Kolanowski, J., Tran, C., Kaur, A., Akerfeldt, M., Rahme, M., Hambley, T., New, E. (2016). A ratiometric fluorescent sensor for the mitochondrial copper pool. Metallomics, 8(9), 915-919. [More Information]

2015

  • Renfrew, A., Bryce, N., Hambley, T. (2015). Cobalt(III) chaperone complexes of curcumin: Photoreduction, cellular accumulation and light-selective toxicity towards tumour cells. Chemistry - A European Journal, 21(43), 15224-15234. [More Information]
  • Shen, C., Harris, B., Dawson, L., Charles (nee Slaviero), K., Hambley, T., New, E. (2015). Fluorescent sensing of monofunctional platinum species. Chemical Communications, 51(29), 6312-6314. [More Information]
  • Roberts, M., Pham, T., Doan, J., Jiang, C., Hambley, T., Greguric, I., Fraser, B. (2015). Radiosynthesis and 'click' conjugation of ethynyl-4-[18F]fluorobenze - an improved [18F]synthon for indirect radiolabeling. Journal of Labelled Compounds and Radiopharmaceuticals, 58(13-14), 473-478. [More Information]

2014

  • Eljack, N., Ma, H., Drucker, J., Shen, C., Hambley, T., New, E., Friedrich, T., Clarke, R. (2014). Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin. Metallomics, 6(11), 2126-2133. [More Information]
  • Klein, A., Hambley, T. (2014). Platinum-Based Anticancer Agents. In Tim Storr (Eds.), Ligand Design in Medicinal Inorganic Chemistry, (pp. 9-45). Chichester, United Kingdom: John Wiley & Sons. [More Information]

2013

  • Renfrew, A., Bryce, N., Hambley, T. (2013). Delivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM study. Chemical Science, 4(9), 3731-3739. [More Information]
  • Zhang, J., Bonnitcha, P., Wexselblatt, E., Klein, A., Najajreh, Y., Gibson, D., Hambley, T. (2013). Facile preparation of mono-, di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design. Chemistry - A European Journal, 19(5), 1672-1676. [More Information]
  • Chen, C., Zhang, J., Aitken, J., Hambley, T. (2013). Influence of equatorial and axial carboxylato ligands on the kinetic inertness of platinum(IV) complexes in the presence of ascorbate and cysteine and within DLD-1 cancer cells. Journal of Medicinal Chemistry, 56(21), 8757-8764. [More Information]

2012

  • Hawkett, B., Hambley, T., Bryce, N., Pham, B., Jain, N. (2012). A method for the treatment of a solid tumour. Patent No. CA2833413 A1, CA2833413 A1, WO2012142669 A1. , Canada, Canada.
  • Bonnitcha, P., Kim, B., Hocking, R., Clegg, J., Turner, P., Neville, S., Hambley, T. (2012). Cobalt complexes with tripodal ligands: Implications for the design of drug chaperones. Dalton Transactions, 41(37), 11293-11304. [More Information]
  • Yamamoto, N., Renfrew, A., Kim, B., Bryce, N., Hambley, T. (2012). Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex. Journal of Medicinal Chemistry, 55(24), 11013-11021. [More Information]

2011

  • Wolf, S., Huynh, T., Bryce, N., Hambley, T., Wakelin, L., Stewart, B., Catchpoole, D. (2011). Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells. BMC Cell Biology, 12(36), 1-11. [More Information]
  • Yadav, P., Beveridge, R., Blay, J., Boyd, A., Chojnacka, M., Decken, A., Deshpande, A., Gardiner, M., Hambley, T., Hughes, M., New, E., et al (2011). Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies. MedChemComm (Medicinal Chemistry Communications), 2(4), 274-277. [More Information]
  • Daly, H., Hall, M., Failes, T., Zhang, M., Foran, G., Hambley, T. (2011). Stabilization of Triam(m)inechloridoplatinum Complexes by Oxidation to Pt(IV). Australian Journal of Chemistry, 64(3), 273-278. [More Information]

2010

  • Ma, Y., Bryce, N., Whan, R., Xiao, L., Li, K., Ruys, A., Hambley, T., Boughton, P. (2010). Growth of DLD-1 Colon Cancer Cells on VariotisTM Scaffolds of Controlled Porosity: A Preliminary Study. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 8, 79-89. [More Information]
  • Bonin, A., Yanez, J., Fukuda, C., Teng, X., Dillon, C., Hambley, T., Lay, P., Davies, N. (2010). Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats. Cancer Chemotherapy and Pharmacology, 66(4), 755-764. [More Information]
  • Battle, A., Bond, A., Chow, A., Daniels, D., Deacon, G., Hambley, T., Junk, P., Mason, D., Wang, J. (2010). Syntheses and structures of N-polyfluorophenyl- and N,N'-bis(polyfluorophenyl)ethane-1,2-diaminato(1- or 2-)platinum(II) complexes. Journal of Fluorine Chemistry, 131(11), 1229-1236. [More Information]

2009

  • Bryce, N., Zhang, J., Whan, R., Yamamoto, N., Hambley, T. (2009). Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: The effect of charge on drug distribution in solid tumour models. Chemical Communications, 2009 (19), 2673-2675. [More Information]
  • Whan, R., Messerle, B., Hambley, T. (2009). Binding of [Pt(1C3)(dien)]2+ to the duplex DNA oligonucleotide 5'-d(TGGCCA)-3': The effect of an appended positive charge on the orientation and location of anthraquinone intercalation. Dalton Transactions, 2009 (6), 932-939. [More Information]
  • Er, H., Hambley, T. (2009). Enantioselectivity and stereoselectivity in the reactions of the enantiomers of the platinum complex [PtCl(2)(ahaz)] (ahaz = 3(R)- or 3(S)-aminohexahydroazepine) with DNA. Journal of Inorganic Biochemistry, 103(2), 168-173. [More Information]

2008

  • Davies, M., Hall, M., Berners-Price, S., Hambley, T. (2008). [(1)H, (15)N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine Complexes. Inorganic Chemistry, 47(17), 7673-7680. [More Information]
  • Yamamoto, N., Danos, S., Bonnitcha, P., Failes, T., New, E., Hambley, T. (2008). Cellular uptake and distribution of cobalt complexes of fluorescent ligands. Journal of Biological Inorganic Chemistry, 13(6), 861-871. [More Information]
  • Hambley, T. (2008). Physiological Targeting to Improve Anticancer Drug Selectivity. Australian Journal of Chemistry, 61(9), 647-653. [More Information]

2007

  • Hall, M., Mellor, H., Callaghan, R., Hambley, T. (2007). Basis for design and development of platinum(IV) anticancer complexes. Journal of Medicinal Chemistry, 50(15), 3403-3411. [More Information]
  • Hall, M., Failes, T., Yamamoto, N., Hambley, T. (2007). Bioreductive activation and drug chaperoning in cobalt pharmaceuticals. Dalton Transactions, (36), 3983-3990. [More Information]
  • Hocking, R., Hambley, T. (2007). Database analysis of transition metal carbonyl bond lengths: Insight into the periodicity of pi back-bonding, sigma donation, and the factors affecting the electronic structure of the TM-C=O moiety. Organometallics, 26(11), 2815-2823. [More Information]

2006

  • Alderden, R., Mellor, H., Modok, S., Hambley, T., Callaghan, R. (2006). Cytotoxic efficacy of an anthraquinone linked platinum anticancer drug. Biochemical Pharmacology, 71(8), 1136-1145. [More Information]
  • Diakos, C., Fenton, R., Hambley, T. (2006). DNA-binding and molecular mechanics modelling studies of the bulky chiral platinum(II) complex [PtCl2(mepyrr)] (mepyrr = N-methyl-2-aminomethylpyrrolidine). Journal of Inorganic Biochemistry, 100(12), 1965-1973. [More Information]
  • Costa, L., Hambley, T., Rocha, W., De Almeida, W., Dos Santos, H. (2006). Kinetics and structural aspects of the cisplatin interactions with guanine: A quantum mechanical description. International Journal of Quantum Chemistry, 106(9), 2129-2144. [More Information]

2005

  • Malina, J., Voitiskova, M., Brabec, V., Diakos, C., Hambley, T. (2005). DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins. Biochemical and Biophysical Research Communications, 332(4), 1034-1041. [More Information]
  • Ramadan, S., Bonin, A., Kennedy, B., Hambley, T., Lay, P. (2005). Nuclear magnetic resonance analysis of indomethacin-induced gastric ulcers. Chemical Research in Toxicology, 18(2), 123-128. [More Information]
  • Hocking, R., Hambley, T. (2005). Structural measures of element-oxygen bond covalency from the changes to the delocalisation of the carboxylate ligand. Dalton Transactions, 2005 (5), 969-978. [More Information]

2004

  • Hall, M., Martin, C., Ferguson, D., Phillips, R., Hambley, T., Callaghan, R. (2004). Comparative Efficacy Of Novel Platinum(IV) Compounds With Established Chemotherapeutic Drugs In Solid Tumour Models. Biochemical Pharmacology, 67(1), 17-30. [More Information]
  • Dillon, C., Hambley, T., Kennedy, B., Lay, P., Weder, J., Zhou, Q. (2004). Copper And Zinc Complexes As Antiinflammatory Drugs. In Astrid Sigel & Helmut Sigel (Eds.), Metal Ions in Biological Systems : Volume 41 : Metal Ions and their Complexes in Medication, (pp. 253-277). New York: Marcel Dekker.
  • Ramadan, S., Hambley, T., Kennedy, B., Lay, P. (2004). Nmr Spectroscopic Characterization Of Copper(Ii) And Zinc(Ii) Complexes Of Indomethacin. Inorganic Chemistry, 43(9), 2943-2946. [More Information]

2003

  • Failes, T., Diakos, C., Underwood, C., Hambley, T., Cullinane, C., Lyons, J. (2003). Can metal complexes serve as hypoxia activated prodrugs? Investigations of a Co(III) complex of the MMP inhibitor marimastat. Journal of Inorganic Biochemistry, 96(1), 128.
  • Field, L., Messerle, B., Rehr, M., Soler, L., Hambley, T. (2003). Cationic iridium(I) complexes as catalysts for the alcoholysis of silanes. Organometallics, 22(12), 2387-2395. [More Information]
  • Hall, M., Hambley, T., Beale, P., Zhang, M., Dillon, C., Foran, G., Stampfl, A., Lai, B. (2003). Does platinum(IV) survive in tumour cells? Journal of Inorganic Biochemistry, 96(1), 141.

2002

  • Hotze, A., Chen, Y., Hambley, T., Parsons, S., Kratochwil, N., Parkinson, J., Munk, V., Sadler, P. (2002). Cis-[PtCl2(NH3){2-(2-hydroxyethyl)pyridine}] - an Analogue of the Anticancer Drug AMD473: Unusual Hydrolysis Rates and pKa Values for the Diaqua Adduct. European Journal of Inorganic Chemistry, 2002 (5), 1035-1039.
  • Weder, J., Dillon, C., Hambley, T., Kennedy, B., Lay, P., Biffin, J., Regtop, H., Davies, N. (2002). Copper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realized. Coordination Chemistry Reviews, 232(1-2), 95-126. [More Information]
  • Battle, A., Deacon, G., Dolman, R., Hambley, T. (2002). Electrochemistry, Protein Binding and Crystal Structures of Platinum(II) and Platinum(IV) Carboxylato Complexes. Australian Journal of Chemistry, 55(11), 699-704. [More Information]

2001

  • Hambley, T., Turner, P., Jackson, T., Kojima,, M., Knott,, R., Lambrecht,, R. (2001). 6,6,9,9-tetramethyl-1,2,5,6,9,9a-hexahydro-imidazo[2,1-d][1,2,5]dithiazepin-1-ium triiodide. Acta Crystallographica. Section E: Structure Reports Online, E57, 315-317.
  • Hall, B., Hanrahan, J., Johnston, G., Hambley, T., Hibbs, D. (2001). 6-Methylflavone. Acta Crystallographica. Section E: Structure Reports Online, E57.
  • Platts, J., Hibbs, D., Hambley, T., Hall, M. (2001). Calculation of the hydrophobicity of platinum drugs. Journal of Medicinal Chemistry, 44(3), 472-474. [More Information]

2000

  • Codd, R., Levina, A., Zhang, L., Hambley, T., Lay, P. (2000). Characterization and X-ray absorption spectroscopic studies of bis[quinato(2)]oxochromate(V). Inorganic Chemistry, 39(5), 990-997.

1999

  • Field, L., Messerle, B., Smernik, R., Hambley, T., Turner, P. (1999). Butenynyl complexes of iron(II) containing the tripodal tetraphosphine ligand P(CH2CH2PMe2)3. Dalton Transactions, (15), 2557-2562. [More Information]
  • Elgafi, S., Field, L., Messerle, B., Turner, P., Hambley, T. (1999). Rhodium complexes containing bidentate imidazolyl ligands: Synthesis and structure. Journal of Organometallic Chemistry, 588(1), 69-77. [More Information]

1997

  • Field, L., Messerle, B., Smernik, R., Hambley, T., Turner, P. (1997). Iron Complexes Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3. Inorganic Chemistry, 36(13), 2884-2892. [More Information]
  • Elgafi, S., Field, L., Messerle, B., Buys, I., Hambley, T. (1997). Trisimidazole complexes of ruthenium and osmium. Journal of Organometallic Chemistry, 538, 119-128. [More Information]

1996

  • Hambley, T., Ling, E., Messerle, B. (1996). Combined NMR and Molecular Mechanics Study of the Isomers Formed in the Reaction of Dichloro(1,4-diazacycloheptane)platinum(II) with the Dinucleotide d(GpG). Inorganic Chemistry, 35(16), 4663-4668. [More Information]

1994

  • Buys, I., Elgafi, S., Field, L., Hambley, T., Messerle, B. (1994). Formation of a Novel Dipyrrolopyrrole Mediated by a 1,4-Diaza-1,3-diene Complex of Iron. Inorganic Chemistry, 33(7), 1539-1542. [More Information]

Selected Grants

2022

  • Biologically inert probes to unravel nutrient directed cellular processing, Ryan R, Hambley T, Kaur A, Australian Research Council (ARC)/Discovery Projects (DP)

2017

  • Fluorescent sensing of the intracellular redox environment, New E, Hambley T, Kaur A, Australian Research Council (ARC)/Discovery Projects (DP)