Cardiometabolic disease

Our aim is to discover novel markers, effectors, and predictors of cardiometabolic disease, which refers to the nexus of cardiovascular disease and obesity-driven diseases like type 2 diabetes.

Obesity-driven metabolic diseases are the major drivers of atherosclerotic cardiovascular disease in the modern era. Our mission is to discover better diagnostic markers, predictors, and therapies for cardiometabolic disease. Our work is closely aligned with the mission of the Charles Perkins Centre, therefore we have many great collaborators based at the centre that help elevate our work.

We have discovered a number of markers of cardiometabolic disease that also predict disease far into the future. For example, we have recently identified a new circulating biomarker that is an independent predictor of diabetes over a decade before diagnosis. We are now investigating therapies targeting these pathways.

• A new pathway links fatty liver disease and type 2 diabetes: Professor Stephen Simpson, Professor Gregory Cooney, Professor David James, Associate Professor Vic Cogger, Dr Samantha Solon-Biet, Associate Professor Paul Witting.
• Cardiovascular disease in the young: Dr Sanjay Patel, Professor Gemma Figtree.

• Dr Yen Chin Koay
• Professor Stephen Simpson
• Professor Gregory Cooney
• Professor David James
• Associate Professor Vic Cogger
• Dr Samantha Solon-Biet
• Associate Professor Paul Witting.
• Dr Sanjay Patel
• Professor Gemma Figtree.