Professor Georges Grau
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Professor Georges Grau

Professor of Vascular Immunology
Pathology, School of Medical Sciences
Bosch Institute
Professor Georges Grau

2006 - present: Professor, Chair of Vascular Immunology, Department of Pathology, School of Medical Sciences, Faculty of Medicine, University of Sydney

1999 - 2006: Professeur des Universites (Physiologie, section 40), Universite de la Mediterranee 1998 - 1999: Research Associate, CNRS, Prof. D. Raoult, Marseille 1997 - 1998: Invited Professor, Department of Pathology, University of Regensburg 1995 - 1997: Chef de Clinique Scientifique, University of Geneva 1992: Privat - Docent (Agregation de l'Enseignement Superieur), Faculty of Medicine, University of Geneva 1991 - 1995: Maitre de'Enseignement et de Recherche at the WHO Centre and at the Department of Pathology, University of Geneva 1989 - 1991: Charge de Recherche, Departement de Pathologie, University of Geneva 1984 - 1988: Assistant en Medecine Fondamentale, Department of Pathology, University of Geneva 1984: M.D. Thesis, University of Geneva 1983: Candidate-Specialist in Internal Medicine, Universite de Liege 1982 - 1995: Research Associate, World Health Organisation, Immunology Research and Training Centre, Prof. P.H. Lambert, University of Geneva, Switzerland 1981 - 1982: Post-Doctoral Fellow, Institut de Pathologie Cellulaire, Prof. M. Bessis, Hopital du Kremlin-Bicetre, Paris, France 1979 - 1983: Resident, Department of Internal Medicine, Prof. H. van Cauwenberghe, Hopital Universitaire de Baviere, Liege 1972 - 1979: Doctor of Medicine (with High Distinction), University of Liege

Immunopathology of microvascular lesions, particularly of cerebral and pulmonary complications of infectious and auto-immune diseases, especially in cerebral malaria, septic shock and multiple sclerosis. Analysis of the cellular and molecular mechanisms of the interactions between microvascular endothelial cells and cells of the immune system. Experience in various in vivo and in vitro experimental systems as well as in clinical studies. More recently, focus on the neurovascular lesion of murine and human cerebral malaria, using co-culture model systems involving brain endothelium, P. falciparum infected erythrocytes, as well as circulating cells, particularly platelets and monocytes.

Additional keywords: endothelium; cytokines; platelets; microparticles; brain diseases; cerebral malaria; sepsis; septic shock

Cancer, Infection and Immunological Conditions, Neurosciences and Mental Health
Project titleResearch student
Understanding the role of lymphocytes in the development of thrombo-inflammation in heparin induced thrombocytopenia (HIT)Jemma FENWICK
Immune mechanisms of blood-brain barrier pathologiesLinda LIN
Investigating Extracellular Vesicles signalling in the pathophysiology of Multiple SclerosisDrishya MAINALI

Publications

Book Chapters

  • Grau, G., Hosseini Beheshti, E. (2021). Extracellular Vesicles and Cerebral Malaria. In Suresh Mathivanan, Pamali Fonseka, Christina Nedeva, Ishara Atukorala (Eds.), New Frontiers: Extracellular Vesicles. Subcellular Biochemistry, (pp. 501-508). Cham: Springer. [More Information]
  • Grau, G., Wassmer, S. (2017). Pathogenetic immune responses in cerebral malaria. In Maria M. Mota, Ana Rodriguez (Eds.), Malaria: Immune Response to Infection and Vaccination, (pp. 67-80). Cham: Springer International Publishing. [More Information]
  • Grau, G., Hunt, N. (2014). Cytokines and Some of Their Effector Mechanisms in Cerebral Malaria Pathogenesis. In M. Hommel and P. G. Kremsner (Eds.), Encyclopedia of Malaria, (pp. 1-11). New York: Springer. [More Information]

Journals

  • Taitz, J., Tan, J., Ni, D., Potier, C., Grau, G., Nanan, R., Macia, L. (2025). Antibiotic-mediated dysbiosis leads to activation of inflammatory pathways. Frontiers in Immunology, 15, 1493991. [More Information]
  • Wassmer, S., de Koning-Ward, T., Grau, G., Pai, S. (2024). Unravelling mysteries at the perivascular space: a new rationale for cerebral malaria pathogenesis. Trends in Parasitology, 40(1), 28-44. [More Information]
  • Tse, B., Ferguson, A., Koay, Y., Grau, G., Don, A., Byrne, S. (2023). Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes. Frontiers in Immunology, 13. [More Information]

Conferences

  • Lee, J., Carter, E., Grau, G., Combes, V., Bonhoure, B., Lay, P. (2009). The investigation of monocyte cell signalling by FT-IR spectroscopy. International Conference on Advanced Vibrational Spectroscopy, N/A: N/A.

Patents

  • Hackett, M., Lay, P., Carter, E., Hunt, N., Grau, G., Gottlieb, D. (2010). Classification of biological samples using spectroscopic analysis. Patent No. WO2009AU01423 20091030.

2025

  • Taitz, J., Tan, J., Ni, D., Potier, C., Grau, G., Nanan, R., Macia, L. (2025). Antibiotic-mediated dysbiosis leads to activation of inflammatory pathways. Frontiers in Immunology, 15, 1493991. [More Information]

2024

  • Wassmer, S., de Koning-Ward, T., Grau, G., Pai, S. (2024). Unravelling mysteries at the perivascular space: a new rationale for cerebral malaria pathogenesis. Trends in Parasitology, 40(1), 28-44. [More Information]

2023

  • Tse, B., Ferguson, A., Koay, Y., Grau, G., Don, A., Byrne, S. (2023). Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes. Frontiers in Immunology, 13. [More Information]
  • Adderley, J., Grau, G. (2023). Host-directed therapies for malaria: possible applications and lessons from other indications. Current opinion in microbiology, 71. [More Information]
  • Batarseh, A., Vafaee, F., Hosseini Beheshti, E., Safarchi, A., Chen, A., Cohen, A., Juillard, A., Hunt, N., Mariani, M., Mitchell, T., Grau, G. (2023). Investigation of Plasma-Derived Lipidome Profiles in Experimental Cerebral Malaria in a Mouse Model Study. International Journal of Molecular Sciences, 24(1), 501. [More Information]

2022

  • Aglas-Leitner, F., Juillard, P., Juillard, A., Byrne, S., Hawke, S., Grau, G., Marsh-Wakefield, F. (2022). Circulating CCR6+ ILC proportions are lower in multiple sclerosis patients. Clinical & Translational Immunology, 11(12). [More Information]
  • Leffler, J., Trend, S., Ward, N., Grau, G., Hawke, S., Byrne, S., Kermode, A., French, M., Hart, P. (2022). Circulating Memory B Cells in Early Multiple Sclerosis Exhibit Increased IgA+ Cells, Globally Decreased BAFF-R Expression and an EBV-Related IgM+ Cell Signature. Frontiers in Immunology, 13, 812317. [More Information]
  • Ford, R., Juillard, P., Hawke, S., Grau, G., Marsh-Wakefield, F. (2022). Cladribine Reduces Trans-Endothelial Migration of Memory T Cells across an In Vitro Blood–Brain Barrier. Journal of Clinical Medicine, 11(20). [More Information]

2021

  • Prashanth, A., Donaghy, H., Stoner, S., Hudson, A., Wheeler, H., Diakos, C., Howell, V., Grau, G., McKelvey, K. (2021). Are In Vitro Human Blood-Brain-Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics? Cancers, 13(5), 955-1-955-19. [More Information]
  • Grau, G., Hosseini Beheshti, E. (2021). Extracellular Vesicles and Cerebral Malaria. In Suresh Mathivanan, Pamali Fonseka, Christina Nedeva, Ishara Atukorala (Eds.), New Frontiers: Extracellular Vesicles. Subcellular Biochemistry, (pp. 501-508). Cham: Springer. [More Information]
  • Ryan, S., Hosseini Beheshti, E., Afrose, D., Ding, X., Xia, B., Grau, G., Little, C., McClements, L., Li, J. (2021). Extracellular vesicles from mesenchymal stromal cells for the treatment of inflammation-related conditions. International Journal of Molecular Sciences, 22(6), 1-34. [More Information]

2020

  • Mutso, M., John, J., Ling, Z., Burt, F., Poo, Y., Liu, X., Žusinaite, E., Grau, G., Hueston, L., Merits, A., King, N., et al (2020). Basic insights into Zika virus infection of neuroglial and brain endothelial cells. Journal of General Virology, 101(6), 622-634. [More Information]
  • Renia, L., Grau, G., Wassmer, S. (2020). CD8+ T cells and human cerebral malaria: a shifting episteme. Journal of Clinical Investigation, 130(3), 1109-1111. [More Information]
  • Ahmadzada, T., Kao, S., Reid, G., Clarke, S., Grau, G., Hosseini Beheshti, E. (2020). Extracellular vesicles as biomarkers in malignant pleural mesothelioma: A review. Critical Reviews in Oncology / Hematology (online), 150, 102949. [More Information]

2019

  • He, S., Chen, D., Hu, M., Zhang, L., Liu, C., Traini, D., Grau, G., Zeng, Z., Lu, J., Zhou, G., et al (2019). Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization. Nanomedicine: Nanotechnology, Biology, and Medicine, 18, 259-271. [More Information]
  • Gramaglia, I., Velez, J., Chang, Y., Caparros-Wanderley, W., Combes, V., Grau, G., Stins, M., van der Heyde, H. (2019). Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak. PloS One, 14(3), 1-16. [More Information]
  • Hosseini Beheshti, E., Grau, G. (2019). Extracellular vesicles and microvascular pathology: decoding the active dialogue. Microcirculation, 26(2), 1-11. [More Information]

2018

  • Cohen, A., Zinger, A., Tiberti, N., Grau, G., Combes, V. (2018). Differential plasma microvesicle and brain profiles of microRNA in experimental cerebral malaria. Malaria Journal, 17(1), 1-13. [More Information]
  • Martin-Alonso, A., Cohen, A., Quispe-Ricalde, M., Foronda, P., Benito, A., Berzosa, P., Valladares, B., Grau, G. (2018). Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-[beta] signalling pathways. Scientific Reports, 8(1), 1-10. [More Information]
  • Niewold, P., Cohen, A., Van Vreden, C., Getts, D., Grau, G., King, N. (2018). Experimental severe malaria is resolved by targeting newly-identified monocyte subsets using immune-modifying particles combined with artesunate. Communications Biology, 1, 1-13. [More Information]

2017

  • Marzook, N., Latham, S., Lynn, H., McKenzie, C., Chaponnier, C., Grau, G., Newsome, T. (2017). Divergent roles of beta- and gamma-actin isoforms during spread of vaccinia virus. Cytoskeleton, 74(4), 170-183. [More Information]
  • Maknitikul, S., Luplertlop, N., Grau, G., Ampawong, S. (2017). Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin. PloS One, 12(7), 1-22. [More Information]
  • Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 187(2), 353-360. [More Information]

2016

  • O'Regan, N., Gegenbauer, K., O'Sullivan, J., Maleki, S., Brophy, T., Dalton, N., Chion, A., Fallon, P., Grau, G., Budde, U., et al (2016). A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood, 127(9), 1192-1201. [More Information]
  • Sorrell, T., Juillard, P., Djordjevic, J., Kaufman-Francis, K., Dietmann, A., Milonig, A., Combes, V., Grau, G. (2016). Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var grubii strain H99 and C gattii strain R265. Microbes and Infection, 18(1), 57-67. [More Information]
  • Combes, V., Latham, S., Wen, B., Allison, A., Grau, G. (2016). DIANNEXIN DOWN-MODULATES TNF-INDUCED ENDOTHELIAL MICROPARTICLE RELEASE BY BLOCKING MEMBRANE BUDDING PROCESS. International Journal of Medical and Health Sciences, 7, 1-11.

2015

  • Ampawong, S., Chaisri, U., Viriyavejakul, P., Prapansilp, P., Grau, G., Turner, G., Pongponratn, E. (2015). A potential role for interleukin-33 and γ-epithelium sodium channel in the pathogenesis of human malaria associated lung injury. Malaria Journal, 14(1), 1-15. [More Information]
  • Bucur, O., Almasan, A., Zubarev, R., Friedman, M., Nicolson, G., Sumazin, P., Leabu, M., Nikolajczyk, B., Avram, D., Kunej, T., Richardson, D., Grau, G., et al (2015). An updated h-index measures both the primary and total scientific output of a researcher. Discoveries, 3(3), 1-6. [More Information]
  • Kam, A., Li, K., Razmovski-Naumovsk, V., Nammi, S., Chan, K., Grau, G., Li, G. (2015). Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells. Journal of Pharmacy and Pharmaceutical Sciences, 18(4), 424-433. [More Information]

2014

  • Khaw, L., Ball, H., Mitchell, A., Grau, G., Stocker, R., Golenser, J., Hunt, N. (2014). Brain endothelial cells increase the proliferation of Plasmodium falciparum through production of soluble factors. Experimental Parasitology, 145(1), 34-41. [More Information]
  • Jaiswal, R., Grau, G., Bebawy, M. (2014). Cellular communication via microparticles: role in transfer of multidrug resistance in cancer. Future Oncology, 10(4), 655-669. [More Information]
  • Hunt, N., Ball, H., Hansen, A., Khaw, L., Guo, J., Bakmiwewa, S., Mitchell, A., Combes, V., Grau, G. (2014). Cerebral malaria: gamma-interferon redux. Frontiers in Cellular and Infection Microbiology, 4, 1-12. [More Information]

2013

  • Jaiswal, R., Luk, F., Dalla, P., Grau, G., Debawy, M. (2013). Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells. PloS One, 8(4), 1-10. [More Information]
  • Roseblade, A., Luk, F., Rawling, T., Ung, A., Grau, G., Bebawy, M. (2013). Cell-Derived Microparticles: New Targets in the Therapeutic Management of Disease. Journal of Pharmacy and Pharmaceutical Sciences, 16(2), 238-253. [More Information]
  • Latham, S., Chaponnier, C., Dugina, V., Couraud, P., Grau, G., Combes, V. (2013). Cooperation between beta- and gamma-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. The FASEB Journal, 27(2), 672-683. [More Information]

2012

  • Razakandrainibe, R., Pelleau, S., Grau, G., Jambou, R. (2012). Antigen presentation by endothelial cells: what role in the pathophysiology of malaria? Trends in Parasitology, 28(4), 151-160. [More Information]
  • Grau, G., Craig, A. (2012). Cerebral malaria pathogenesis: revisiting parasite and host contributions. Future Microbiology, 7(2), 291-302. [More Information]
  • Faille, D., El Assaad, F., Mitchell, A., Alessi, M., Chimini, G., Fusai, T., Grau, G., Combes, V. (2012). Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells. Journal of Cellular and Molecular Medicine, 16(8), 1731-1738. [More Information]

2011

  • Hackett, M., McQuillan, J., El Assaad, F., Aitken, J., Levina, A., Cohen, D., Siegele, R., Carter, E., Grau, G., Hunt, N., Lay, P. (2011). Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. Analyst, 136(14), 2941-2952. [More Information]
  • Nantakomol, D., Dondorp, A., Krudsood, S., Udomsangpetch, R., Pattanapanyasat, K., Combes, V., Grau, G., White, N., Viriyavejakul, P., Day, N., et al (2011). Circulating red cell-derived microparticles in human malaria. The Journal of Infectious Diseases, 203(5), 700-706. [More Information]
  • Hempel, C., Combes, V., Hunt, N., Kurtzhals, J., Grau, G. (2011). CNS Hypoxia Is More Pronounced in Murine Cerebral than Noncerebral Malaria and is Reversed by Erythropoietin. American Journal of Pathology, 179(4), 1939-1950. [More Information]

2010

  • Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Combes, V., Grau, G., Amvam Zollo, P. (2010). Biochemical markers of nutritional status and childhood malaria severity in Cameroon. British Journal of Nutrition, 104(6), 886-892. [More Information]
  • Hackett, M., Lay, P., Carter, E., Hunt, N., Grau, G., Gottlieb, D. (2010). Classification of biological samples using spectroscopic analysis. Patent No. WO2009AU01423 20091030.
  • Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Amvam Zollo, P., Grau, G., Combes, V. (2010). Elevated Cell-Specific Microparticles Are a Biological Marker for Cerebral Dysfunctions in Human Severe Malaria. PloS One, 5(10), e13415 - 1-e13415 - 9. [More Information]

2009

  • Zhang, W., Wu, L., Liu, H., Ye, L., Xin, Y., Grau, G., Lou, J. (2009). Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation. Microvascular research, 78(3), 379-385. [More Information]
  • El-Assaad, F., Combes, V., Grau, G. (2009). Citicoline (CDP-choline): What role in the treatment of complications of infectious diseases. International Journal of Biochemistry and Cell Biology, 41(7), 1467-1470. [More Information]
  • Bruzzone, R., Dubois-Dalcq, M., Grau, G., Griffin, D., Kristensson, K. (2009). Infectious diseases of the nervous system and their impact in developing countries. PLoS Pathogens, 5(2), e1000199. [More Information]

2008

  • von zur Muhlen, C., Sibson, N., Peter, K., Campbell, S., Wilainam, P., Grau, G., Bode, C., Choudhury, R., Anthony, D. (2008). A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI. Journal of Clinical Investigation, 118(3), 1198-1207. [More Information]
  • Togbe, D., de Sousa, P., Fauconnier, M., Boissay, V., Fick, L., Scheu, S., Pfeffer, K., Menard, R., Grau, G., Doan, B., Hansen, A., Ball, H., Hunt, N., et al (2008). Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PloS One, 3(7), e2608-1-e2608-12. [More Information]
  • Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Grau, G., Combes, V., Amvam Zollo, P. (2008). Clinical presentation, haematological indices and management of children with severe and uncomplicated malaria in Douala, Cameroon. Pakistan Journal of Biological Sciences, 11(20), 2401-2406. [More Information]

2007

  • Bechah, Y., Capo, C., Grau, G., Raoult, D., Mege, J. (2007). A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. Microbes and Infection, 9(7), 898-906. [More Information]
  • Delahaye, N., Coltel, N., Puthier, D., Barbier, M., Benech, P., Joly, F., Iraqi, F., Grau, G., Nguyen, C., Rihet, P. (2007). Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. BMC Genomics, 8(452), 1-16. [More Information]
  • Penet, M., Kober, F., Confort-Gouny, S., Le Fur, Y., Dalmasso, C., Coltel, N., Liprandi, A., Gulian, J., Grau, G., Cozzone, P., et al (2007). Magnetic Resonance Spectroscopy Reveals an Impaired Brain Metabolic Profile in Mice Resistant to Cerebral Malaria Infected with Plasmodium berghei ANKA. Journal of Biological Chemistry, 282(19), 14505-14514. [More Information]

2006

  • van der Heyde, H., Nolan, J., Combes, V., Gramaglia, I., Grau, G. (2006). A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends in Parasitology, 22(11), 503-508. [More Information]
  • Meghari, S., Rolain, J., Grau, G., Platt, E., Barrassi, L., Mege, J., Raoult, D. (2006). Antiangiogenic Effect of Erythromycin: An In Vitro Model of Bartonella quintana Infection. The Journal of Infectious Diseases, 193(3), 380-386. [More Information]
  • Hunt, N., Grau, G. (2006). Blood-brain barrier in parasitic disease. International Journal for Parasitology, 36(5), 503-504. [More Information]

2005

  • Combes, V., Coltel, N., Alibert, M., van Eck, M., Raymond, C., Juhan-Vague, I., Grau, G., Chimini, G. (2005). ABCA1 Gene Deletion Protects against Cerebral Malaria: Potential Pathogenic Role of Microparticles in Neuropathology. American Journal of Pathology, 166(1), 295-302. [More Information]
  • Combes, V., De Souza, J., Rénia, L., Hunt, N., Grau, G. (2005). Cerebral malaria: Which parasite? Which model? Drug Discovery Today: Disease Models, 2(2), 141-147. [More Information]
  • Penet, M., Viola, A., Confort-Gouny, S., Le Fur, Y., Duhamel, G., Kober, F., Ibarrola, D., Izquierdo, M., Coltel, N., Gharib, B., Grau, G., et al (2005). Imaging Experimental Cerebral Malaria In Vivo: Significant Role of Ischemic Brain Edema. Journal of Neuroscience, 25(32), 7352-7358. [More Information]

2004

  • Coltel, N., Combes, V., Hunt, N., Grau, G. (2004). Cerebral Malaria - A Neurovascular Pathology with Many Riddles Still to be Solved. Current Neurovascular Research, 1(2), 91-110.
  • Combes, V., Taylor, T., Juhan-Vague, I., Mege, J., Mwenechanya, J., Tembo, M., Grau, G., Molyneux, M. (2004). Circulating Endothelial Microparticles in Malawian Children With Severe Falciparum Malaria Complicated With Coma. JAMA - Journal of the American Medical Association, 291(21), 2542-2544.
  • Combes, V., Rosenkranz, A., Redard, M., Pizzolato, G., Lepidi, H., Vestweber, D., Mayadas, T., Grau, G. (2004). Pathogenic Role of P-Selectin in Experimental Cerebral Malaria. American Journal of Pathology, 164(3), 781-786. [More Information]

2003

  • Hunt, N., Grau, G. (2003). Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends in Immunology, 24(9), 491-499. [More Information]
  • Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenesis of cerebral malaria: facts and hypotheses. Medecine Tropicale, 63(3), 254-257.
  • Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenèse du Neuropaludisme: faits et hypothèses. Revista da Sociedade Brasileira de Medicina Tropical (RSBMT), (63), 254-257.

2002

  • Lucas, R., Grau, G., Matthay, M., Wendel, A. (2002). Functional dissection of Tumour Necrosis Factor in liver, brain and lungs. Trends in Immunology, (3), 47-59.
  • Dou, L., Cerini, C., Brunet, P., Guilianelli, C., Moal, V., Grau, G., De Smet, R., Vanholder, R., Sampol, J., Berland, Y. (2002). P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney International, 62(6), 1999-2009.
  • Hamacher, J., Lucas, R., Lijnen, H., Buschke, S., Dunant, Y., Wendel, A., Grau, G., Suter, P., Ricou, B. (2002). Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 166(5), 651-656.

2001

  • Lucas, R., Montesano, R., Pepper, M., Hafner, M., Sablon, E., Dunant, Y., Grau, G., De Baetselier, P., Mannel, D., Fransen, L. (2001). Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. International Journal of Cancer, 91(4), 543-549.
  • Lou, J., Lucas, R., Grau, G. (2001). Pathogenesis of Cerebral Malaria: Recent Experimental Data and Possible Applications for Humans. Clinical Microbiology Reviews, 14(4), 810-820.
  • Stoelcker, B., Hehlgans, T., Weigl, K., Bluethmann, H., Grau, G., Mannel, D. (2001). Requirement for tumour necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria. Infection and Immunity, 70(10), 5857-5859.

Selected Grants

2021

  • Metal Virulence and Therapeutic Factors in Pathogen Bioinorganic Chemistry, Lay P, Grau G, Australian Research Council (ARC)/Discovery Projects (DP)

2020

  • The maternal gut microbiota drives foetal Thymic T cell development, Nanan R, Macia L, Grau G, King N, Australian Research Council (ARC)/Discovery Projects (DP)
  • A new regenerative therapy for treating thumb base osteoarthritis, Li J, Hosseini Beheshti E, Gentile C, Little C, Grau G, The Lincoln Centre/Research Grant