Book Chapters

• Grau, G., Hunt, N. (2014). Cytokines and Some of Their Effector Mechanisms in Cerebral Malaria Pathogenesis. In M. Hommel and P. G. Kremsner (Eds.), Encyclopedia of Malaria, (pp. 1-11). New York: Springer. [More Information]
• Combes, V., El-Assaad, F., Grau, G. (2011). Immunopathology and pathophysiology of cerebral malaria. In Mauro Bendinelli, Herman Friedman and Andreas Seyfang (Eds.), Infectious Agents and Pathogenesis. tba: Springer Publishing Company.
• Combes, V., Grau, G. (2007). Microvascular endothelium and cerebral malaria. In William Aird (Eds.), The Endothelium: A Comprehensive Reference. CRC Press.
• Combes, V., Lou, J., Grau, G. (2007). The endothelium in cerebral malaria - Both a target cell and a major player. In William Aird (Eds.), Endothelial Biomedicine, (pp. 1303-1310). United States: Cambridge University Press.
• Combes, V., Grau, G. (2006). Cytokines in defence and pathology of the central nervous system. In Richard M. Ransohoff, Etty N. Benveniste (Eds.), Cytokines and the CNS - 2nd Edition, (pp. 243-268). United States: CRC Press.

Journals

• Marzook, N., Latham, S., Lynn, H., McKenzie, C., Chaponnier, C., Grau, G., Newsome, T. (2017). Divergent roles of beta- and gamma-actin isoforms during spread of vaccinia virus. Cytoskeleton, 74(4), 170-183. [More Information]
• Maknitikul, S., Luplertlop, N., Grau, G., Ampawong, S. (2017). Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin. PloS One, 12(7), 1-22. [More Information]
• Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B, 187(2), 353-360. [More Information]
• Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B, 187(2), 353-360. [More Information]
• Claser, C., De Souza, J., Thorburn, S., Grau, G., Riley, E., Renia, L., Hafalla, J. (2017). Host resistance to Plasmodium-induced acute immune pathology is regulated by IL-10 receptor signalling. Infection and Immunity, 85(6), 1-9. [More Information]
• Lee, J., Wen, B., Carter, E., Combes, V., Grau, G., Lay, P. (2017). Infrared spectroscopic characterization of monocytic microvesicles (microparticles) released upon lipopolysaccharide stimulation. The FASEB Journal, 31(7), 2817-2827. [More Information]
• Gramaglia, I., Velez, J., Combes, V., Grau, G., Wree, M., van der Heyde, H. (2017). Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response. Blood, 129(12), 1669-1679. [More Information]
• Wassmer, S., Grau, G. (2017). Severe malaria: what's new on the pathogenesis front? International Journal for Parasitology, 47(42796), 145-152. [More Information]
• Zhao, Y., Ting, K., Li, J., Cogger, V., Chen, J., Johansson-Percival, A., Ngiow, S., Holst, J., Grau, G., Goel, S., McCaughan, G., Vadas, M., Gamble, J., et al (2017). Targeting vascular endothelial-cadherin in tumor-associated blood vessels promotes T-cell-mediated immunotherapy. Cancer Research, 77(16), 4434-4447. [More Information]
• Ghadiri, M., Young, P., Jarolimek, W., Grau, G., Oliver, B., Traini, D. (2017). The effect of non-specific tight junction modulators on the transepithelial transport of poorly permeable drugs across airway epithelial cells. Journal of Drug Targeting, 25(4), 342-349. [More Information]
• Hunt, N., Too, L., Khaw, L., Guo, J., Hee, L., Mitchell, A., Grau, G., Ball, H. (2017). The kynurenine pathway and parasitic infections that affect CNS function. Neuropharmacology, 112(Pt B), 389-398. [More Information]
• O'Regan, N., Gegenbauer, K., O'Sullivan, J., Maleki, S., Brophy, T., Dalton, N., Chion, A., Fallon, P., Grau, G., Budde, U., et al (2016). A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood, 127(9), 1192-1201. [More Information]
• Sorrell, T., Juillard, P., Djordjevic, J., Kaufman-Francis, K., Dietmann, A., Milonig, A., Combes, V., Grau, G. (2016). Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var grubii strain H99 and C gattii strain R265. Microbes and Infection, 18(1), 57-67. [More Information]
• Combes, V., Latham, S., Wen, B., Allison, A., Grau, G. (2016). DIANNEXIN DOWN-MODULATES TNF-INDUCED ENDOTHELIAL MICROPARTICLE RELEASE BY BLOCKING MEMBRANE BUDDING PROCESS. International Journal of Medical and Health Sciences, 7, 1-11.
• Ghadiri, M., Mamlouk, M., Spicer, P., Jarolimek, W., Grau, G., Young, P., Traini, D. (2016). Effect of polyunsaturated fatty acids (PUFAs) on airway epithelial cells' tight junction. Pulmonary Pharmacology and Therapeutics, 40, 30-38. [More Information]
• Tiberti, N., Latham, S., Bush, S., Cohen, A., Opoka, R., John, C., Juillard, A., Grau, G., Combes, V. (2016). Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content. Scientific Reports, 6, 1-15. [More Information]
• Zinger, A., Latham, S., Combes, V., Byrne, S., Barnett, M., Hawke, S., Grau, G. (2016). Plasma levels of endothelial and B-cell-derived microparticles are restored by fingolimod treatment in multiple sclerosis patients. Multiple Sclerosis Journal, 22(14), 1883-1887. [More Information]
• Wassmer, S., Grau, G. (2016). Platelets as pathogenetic effectors and killer cells in cerebral malaria. Expert Review of Hematology, 9(6), 515-517. [More Information]
• Carvalho, T., Morahan, B., John von Freyenda, S., Boeuf, P., Grau, G., Garcia-Bustosa, J., Doerig, C. (2016). The ins and outs of phosphosignalling in Plasmodium: Parasite regulation and host cell manipulation. Molecular and Biochemical Parasitology, 208(1), 2-15. [More Information]
• Li, J., Zhao, Y., Lu, Y., Ritchie, W., Grau, G., Vadas, M., Gamble, J. (2016). The Poly-cistronic miR-23-27-24 complexes target endothelial cell junctions: differential functional and molecular effects of miR-23a and miR-23b. Molecular Therapy - Nucleic Acids, 5(8), 1-12. [More Information]
• Ampawong, S., Chaisri, U., Viriyavejakul, P., Prapansilp, P., Grau, G., Turner, G., Pongponratn, E. (2015). A potential role for interleukin-33 and γ-epithelium sodium channel in the pathogenesis of human malaria associated lung injury. Malaria Journal, 14(1), 1-15. [More Information]
• Bucur, O., Almasan, A., Zubarev, R., Friedman, M., Nicolson, G., Sumazin, P., Leabu, M., Nikolajczyk, B., Avram, D., Kunej, T., Richardson, D., Grau, G., et al (2015). An updated h-index measures both the primary and total scientific output of a researcher. Discoveries, 3(3), 1-6. [More Information]
• Kam, A., Li, K., Razmovski-Naumovsk, V., Nammi, S., Chan, K., Grau, G., Li, G. (2015). Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells. Journal of Pharmacy and Pharmaceutical Sciences, 18(4), 424-433. [More Information]
• Hochman, S., Madaline, T., Wassmer, S., Mbale, E., Choi, N., Seydel, K., Whitten, R., Varughese, J., Grau, G., Kamiza, S., et al (2015). Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. MBIO, 6(5), 1-12. [More Information]
• Latham, S., Tiberti, N., Gokoolparsadh, N., Holdaway, K., Couraud, P., Grau, G., Combes, V. (2015). Immuno-analysis of microparticles: probing at the limits of detection. Scientific Reports, 5, 1-13. [More Information]
• Hackett, M., Aitken, J., El Assaad, F., McQuillan, J., Carter, E., Ball, H., Tobin, M., Paterson, D., De Jonge, M., Siegele, R., Grau, G., Hunt, N., Lay, P., et al (2015). Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites. Science Advances, 6(4), 7-16. [More Information]
• Cohen, A., Combes, V., Grau, G. (2015). MicroRNAs and Malaria – A Dynamic Interaction Still Incompletely Understood. Journal of Neuroinfectious Diseases, 6(1), 1-12. [More Information]
• Whittington, C., Grau, G., Murphy, C., Thompson, M. (2015). Unusual angiogenic factor plays a role in lizard pregnancy but is not unique to viviparity. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 324B (2), 152-158. [More Information]
• Danastas, K., Combes, V., Lindsay, L., Grau, G., Thompson, M., Murphy, C. (2015). VEGF111: New insights in tissue invasion. Frontiers in Physiology, 6, 1-5. [More Information]
• Grau, G., Thompson, M., Murphy, C. (2015). VEGF: Inflammatory paradoxes. Pathogens and Global Health, 109(6), 253-254. [More Information]
• Khaw, L., Ball, H., Mitchell, A., Grau, G., Stocker, R., Golenser, J., Hunt, N. (2014). Brain endothelial cells increase the proliferation of Plasmodium falciparum through production of soluble factors. Experimental Parasitology, 145(1), 34-41. [More Information]
• Jaiswal, R., Grau, G., Bebawy, M. (2014). Cellular communication via microparticles: role in transfer of multidrug resistance in cancer. Future Oncology, 10(4), 655-669. [More Information]
• Hunt, N., Ball, H., Hansen, A., Khaw, L., Guo, J., Bakmiwewa, S., Mitchell, A., Combes, V., Grau, G. (2014). Cerebral malaria: gamma-interferon redux. Frontiers in Cellular and Infection Microbiology, 4, 1-12. [More Information]
• Ampawong, S., Chaisri, U., Viriyavejakul, P., Nontprasert, A., Grau, G., Pongponratn, E. (2014). Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression. International Journal of Clinical and Experimental Pathology, 7(5), 2056-2067.
• Wheway, J., Latham, S., Combes, V., Grau, G. (2014). Endothelial Microparticles Interact with and Support the Proliferation of T Cells. The Journal of Immunology, 193(7), 3378-3387. [More Information]
• Wen, B., Combes, V., Bonhoure, A., Weksler, B., Couraud, P., Grau, G. (2014). Endotoxin-Induced Monocytic Microparticles Have Contrasting Effects on Endothelial Inflammatory Responses. PloS One, 9(3), e91597. [More Information]
• El-Assaad, F., Combes, V., Grau, G., Jambou, R. (2014). Potential Efficacy of Citicoline as Adjunct Therapy in Treatment of Cerebral Malaria. Antimicrobial Agents and Chemotherapy, 58(1), 602-605. [More Information]
• El Assaad, F., Wheway, J., Hunt, N., Grau, G., Combes, V. (2014). Production, fate and pathogenicity of plasma microparticles in murine cerebral malaria. PLoS Pathogens, 10(3), 1-14. [More Information]
• Pai, S., Qin, J., Cavanagh, L., Mitchell, A., El-Assaad, F., Jain, R., Combes, V., Hunt, N., Grau, G., Weninger, W. (2014). Real-Time Imaging Reveals the Dynamics of Leukocyte Behaviour during Experimental Cerebral Malaria Pathogenesis. PLoS Pathogens, 10(7), 1-17. [More Information]
• Jaiswal, R., Luk, F., Dalla, P., Grau, G., Debawy, M. (2013). Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells. PloS One, 8(4), 1-10. [More Information]
• Roseblade, A., Luk, F., Rawling, T., Ung, A., Grau, G., Bebawy, M. (2013). Cell-Derived Microparticles: New Targets in the Therapeutic Management of Disease. Journal of Pharmacy and Pharmaceutical Sciences, 16(2), 238-253. [More Information]
• Latham, S., Chaponnier, C., Dugina, V., Couraud, P., Grau, G., Combes, V. (2013). Cooperation between beta- and gamma-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. The FASEB Journal, 27(2), 672-683. [More Information]
• Razakandrainibe, R., Combes, V., Grau, G., Jambou, R. (2013). Crossing the wall: The opening of endothelial cell junctions during infectious diseases. The International Journal of Biochemistry and Cell Biology, 45(7), 1165-1173. [More Information]
• El-Assaad, F., Wheway, J., Mitchell, A., Lou, J., Hunt, N., Combes, V., Grau, G. (2013). Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infection and Immunity, 81(11), 3984-3991. [More Information]
• Dietmann, A., Millonig, A., Combes, V., Couraud, P., Kachlany, S., Grau, G. (2013). Effects of aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells. Microbial Pathogenesis, 61 - 62, 43-50. [More Information]
• Khaw, L., Ball, H., Golenser, J., Combes, V., Grau, G., Wheway, J., Mitchell, A., Hunt, N. (2013). Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria. PloS One, 8(7), 1-13. [More Information]
• Li, C., Eaton, S., Young, P., Lee, M., Shuttleworth, R., Humphreys, D., Grau, G., Combes, V., Bebawy, M., Gong, J., Buckland, M., et al (2013). Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biology, 10(8), 1333-1344. [More Information]
• Lee, J., Siegele, R., Pastuovic, Z., Hackett, M., Hunt, N., Grau, G., Cohen, D., Lay, P. (2013). Light and heavy ion beam analysis of thin biological sections. Nuclear Instruments and Methods in Physics Research B, 306, 129-133. [More Information]
• Gong, J., Luk, F., Jaiswal, R., George, A., Grau, G., Bebawy, M. (2013). Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance. European Journal of Pharmacology, 721(1-3), 116-125. [More Information]
• Walters, S., Kieckbusch, J., Nagalingam, G., Swain, A., Latham, S., Grau, G., Britton, W., Combes, V., Saunders, B. (2013). Microparticles from Mycobacteria-Infected Macrophages Promote Inflammation and Cellular Migration. The Journal of Immunology, 190(2), 669-677. [More Information]
• Lu, J., Luk, F., Gong, J., Jaiswal, R., Grau, G., Bebawy, M. (2013). Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways. Pharmacological Research, 76, 77-83. [More Information]
• Liu, H., Zhang, W., Jia, Y., Yu, Q., Grau, G., Peng, L., Ran, Y., Yang, Z., Deng, H., Lou, J. (2013). Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death and Disease, 4(10), 1-11. [More Information]
• Wheway, J., Obeid, S., Couraud, P., Combes, V., Grau, G. (2013). The brain microvascular endothelium supports t cell proliferation and has potential for alloantigen presentation. PloS One, 8(1), 1-8. [More Information]
• Razakandrainibe, R., Pelleau, S., Grau, G., Jambou, R. (2012). Antigen presentation by endothelial cells: what role in the pathophysiology of malaria? Trends in Parasitology, 28(4), 151-160. [More Information]
• Grau, G., Craig, A. (2012). Cerebral malaria pathogenesis: revisiting parasite and host contributions. Future Microbiology, 7(2), 291-302. [More Information]
• Faille, D., El Assaad, F., Mitchell, A., Alessi, M., Chimini, G., Fusai, T., Grau, G., Combes, V. (2012). Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells. Journal of Cellular and Molecular Medicine, 16(8), 1731-1738. [More Information]
• Hackett, M., Lee, J., El Assaad, F., McQuillan, J., Carter, E., Grau, G., Hunt, N., Lay, P. (2012). FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: General implications for disease neurochemistry. ACS Chemical Neuroscience, 3(12), 1017-1024. [More Information]
• Jaiswal, R., Luk, F., Gong, J., Mathys, J., Grau, G., Bebawy, M. (2012). Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Molecular Cancer, 11, 1-13. [More Information]
• Jaiswal, R., Gong, J., Sambasivam, S., Combes, V., Mathys, J., Davey, R., Grau, G., Bebawy, M. (2012). Microparticle-associated nucleic acids mediate trait dominance in cancer. The FASEB Journal, 26(1), 420-429. [More Information]
• Gong, J., Jaiswal, R., Mathys, J., Combes, V., Grau, G., Bebawy, M. (2012). Microparticles and their emerging role in cancer multidrug resistance. Cancer Treatment Reviews, 38(3), 226-234. [More Information]
• Combes, V., Guillemin, G., Chan-Ling, T., Hunt, N., Grau, G. (2012). The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. Trends in Parasitology, 28(8), 311-319. [More Information]
• Hafalla, J., Claser, C., Couper, K., Grau, G., Renia, L., De Souza, J., Riley, E. (2012). The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathogens, 8(2), 1-12. [More Information]
• Craig, A., Grau, G., Janse, C., Kazura, J., Milner, D., Barnwell, J., Turner, G., Langhorne, J. (2012). The Role of Animal Models for Research on Severe Malaria. PLoS Pathogens, 8(2), 1-9. [More Information]
• Hackett, M., McQuillan, J., El Assaad, F., Aitken, J., Levina, A., Cohen, D., Siegele, R., Carter, E., Grau, G., Hunt, N., Lay, P. (2011). Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. The Analyst, 136(14), 2941-2952. [More Information]
• Nantakomol, D., Dondorp, A., Krudsood, S., Udomsangpetch, R., Pattanapanyasat, K., Combes, V., Grau, G., White, N., Viriyavejakul, P., Day, N., et al (2011). Circulating red cell-derived microparticles in human malaria. The Journal of Infectious Diseases, 203(5), 700-706. [More Information]
• Hempel, C., Combes, V., Hunt, N., Kurtzhals, J., Grau, G. (2011). CNS Hypoxia Is More Pronounced in Murine Cerebral than Noncerebral Malaria and is Reversed by Erythropoietin. The American Journal of Pathology, 179(4), 1939-1950. [More Information]
• McQuillan, J., Mitchell, A., Ho, Y., Combes, V., Ball, H., Golenser, J., Grau, G., Hunt, N. (2011). Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. International Journal for Parasitology, 41(2), 155-163. [More Information]
• El Assaad, F., Hempel, C., Combes, V., Mitchell, A., Ball, H., Kurtzhals, J., Hunt, N., Mathys, J., Grau, G. (2011). Differential MicroRNA Expression in Experimental Cerebral and Noncerebral Malaria. Infection and Immunity, 79(6), 2379-2384. [More Information]
• Saggu, R., Faille, D., Grau, G., Cozzone, P., Viola, A. (2011). In the eye of experimental cerebral malaria. The American Journal of Pathology, 179(3), 1104-1109. [More Information]
• Jambou, R., El Assaad, F., Combes, V., Grau, G. (2011). In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria. Malaria Journal, 10(1), A346-1-A346-5. [More Information]
• Hackett, M., Siegele, R., El Assaad, F., McQuillan, J., Aitken, J., Carter, E., Grau, G., Hunt, N., Cohen, D., Lay, P. (2011). Investigation of the mouse cerebellum using STIM and μ-PIXE spectrometric and FTIR spectroscopic mapping and imaging. Nuclear Instruments and Methods in Physics Research B, 269(20), 2260-2263. [More Information]
• Moxon, C., Grau, G., Craig, A. (2011). Malaria: modification of the red blood cell and consequences in the human host. British Journal of Haematology, 154(6), 670-679. [More Information]
• Ling, Z., Combes, V., Grau, G., King, N. (2011). Microparticles as immune regulators in infectious disease - an opinion. Frontiers in Immunology, 2(67), 1-8. [More Information]
• Barbier, M., Faille, D., Loriod, B., Textoris, J., Camus, C., Puthier, D., Flori, L., Wassmer, S., Victorero, G., Alessi, M., Grau, G., et al (2011). Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria. PloS One, 6(5), e19651-1-e19651-14. [More Information]
• Ampawong, S., Combes, V., Hunt, N., Radford, J., Chan-Ling, T., Pongponratn, E., Grau, G. (2011). Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. International Journal of Clinical and Experimental Pathology, 4(6), 566-574. [More Information]
• Hee, L., Dinudom, A., Mitchell, A., Grau, G., Cook, D., Hunt, N., Ball, H. (2011). Reduced activity of the epithelial sodium channel in malaria-induced pulmonary oedema in mice. International Journal for Parasitology, 41(1), 81-88. [More Information]
• Wassmer, S., Moxon, C., Taylor, T., Grau, G., Molyneux, M., Craig, A. (2011). Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cellular Microbiology Online, 13(2), 198-209. [More Information]
• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Combes, V., Grau, G., Amvam Zollo, P. (2010). Biochemical markers of nutritional status and childhood malaria severity in Cameroon. British Journal of Nutrition, 104(6), 886-892. [More Information]
• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Amvam Zollo, P., Grau, G., Combes, V. (2010). Elevated Cell-Specific Microparticles Are a Biological Marker for Cerebral Dysfunctions in Human Severe Malaria. PloS One, 5(10), e13415 - 1-e13415 - 9. [More Information]
• Carpintero, R., Gruaz, L., Brandt, K., Scanu, A., Faille, D., Combes, V., Grau, G., Burger, D. (2010). HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production. PloS One, 5(7), e11869-1-e11869-8. [More Information]
• Combes, V., El-Assaad, F., Faille, D., Jambou, R., Hunt, N., Grau, G. (2010). Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Progress in Neurobiology, 91(2), 140-151. [More Information]
• Hunt, N., Grau, G., Engwerda, C., Barnum, S., van der Heyde, H., Hansen, D., Schofield, L., Golenser, J. (2010). Murine cerebral malaria: the whole story. Trends in Parasitology, 26(6), 272-4. [More Information]
• Couper, K., Barnes, T., Hafalla, J., Combes, V., Ryffel, B., Secher, T., Grau, G., Riley, E., De Souza, J. (2010). Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation. PLoS Pathogens, 6(1), e1000744-1-e1000744-13. [More Information]
• Jambou, R., Combes, V., Mege-Jambou, M., Weksler, B., Couraud, P., Grau, G. (2010). Plasmodium falciparum Adhesion on Human Brain Microvascular Endothelial Cells Involves Transmigration-Like Cup Formation and Induces Opening of Intercellular Junctions. PLoS Pathogens, 6(7), 1-13. [More Information]
• Bridges, D., Bunn, J., Van Mourik, J., Grau, G., Preston, R., Molyneux, M., Combes, V., O'Donnell, J., De Laat, B., Craig, A. (2010). Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings. Blood, 115(7), 1472-1474. [More Information]
• Mitchell, A., Pradel, L., Chasson, L., Van Rooijen, N., Grau, G., Hunt, N., Chimini, G. (2010). Technical Advance: Autofluorescence as a tool for myeloid cell analysis. Journal of Leukocyte Biology, 88(3), 597-603. [More Information]
• Zhang, W., Wu, L., Liu, H., Ye, L., Xin, Y., Grau, G., Lou, J. (2009). Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation. Microvascular research, 78(3), 379-385. [More Information]
• El-Assaad, F., Combes, V., Grau, G. (2009). Citicoline (CDP-choline): What role in the treatment of complications of infectious diseases. The International Journal of Biochemistry and Cell Biology, 41(7), 1467-1470. [More Information]
• Bruzzone, R., Dubois-Dalcq, M., Grau, G., Griffin, D., Kristensson, K. (2009). Infectious diseases of the nervous system and their impact in developing countries. PLOS Pathogens, 5(2), e1000199. [More Information]
• Bebawy, M., Combes, V., Lee, E., Jaiswal, R., Gong, J., Bonhoure, A., Grau, G. (2009). Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells. Leukemia, 23(9), 1643-1649. [More Information]
• Gouado, I., Pankoui Mfonkeu, J., Fotso, H., Zambou, O., Nguele, S., Combes, V., Grau, G., Amvam Zollo, P. (2009). Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon. The Pediatric Infectious Disease Journal, 28(12), 1081-1084. [More Information]
• Faille, D., Combes, V., Mitchell, A., Fontaine, A., Juhan-Vague, I., Alessi, M., Chimini, G., Fusai, T., Grau, G. (2009). Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium. The F A S E B Journal, 23(10), 3449-3458. [More Information]
• Faille, D., El Assaad, F., Alessi, M., Fusai, T., Combes, V., Grau, G. (2009). Platelet-endothelial cell interactions in cerebral malaria: The end of a cordial understanding. Thrombosis and Haemostasis, 102(6), 1093-1102. [More Information]
• Bechah, Y., Capo, C., Grau, G., Raoult, D., Mege, J. (2009). Rickettsia prowazekii infection of endothelial cells increases leukocyte adhesion through alpha (v)beta(3) integrin engagement. Clinical Microbiology and Infection, 15(Suppl 2), 249-250. [More Information]
• Larkin, D., de Laat, M., Jenkins, P., Bunn, J., Craig, A., Terraube, V., Preston, R., Donkor, C., Grau, G., Van Mourik, J., et al (2009). Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. PLoS Pathogens, 5(3), 1-8. [More Information]
• von zur Muhlen, C., Sibson, N., Peter, K., Campbell, S., Wilainam, P., Grau, G., Bode, C., Choudhury, R., Anthony, D. (2008). A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI. Journal of Clinical Investigation, 118(3), 1198-1207. [More Information]
• Togbe, D., de Sousa, P., Fauconnier, M., Boissay, V., Fick, L., Scheu, S., Pfeffer, K., Menard, R., Grau, G., Doan, B., Hansen, A., Ball, H., Hunt, N., et al (2008). Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PloS One, 3(7), e2608-1-e2608-12. [More Information]
• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Grau, G., Combes, V., Amvam Zollo, P. (2008). Clinical presentation, haematological indices and management of children with severe and uncomplicated malaria in Douala, Cameroon. Pakistan Journal of Biological Sciences, 11(20), 2401-2406. [More Information]
• Hunt, N., Mitchell, A., Hee, L., Xu, Y., Ho, Y., McQuillan, J., Sanchez-Perez, A., Miu, J., Weiser, S., Austin, C., Grau, G., Combes, V., Jambou, R., Ball, H. (2008). Early interactions between malaria-infected erythrocytes and the innate immune system determine the course of immune and immunopathological outcomes. International Journal for Parasitology, 38(Suppl 1), S23-S24. [More Information]
• Wu, L., Zhang, W., Niu, J., Ye, L., Yang, Z., Grau, G., Lou, J. (2008). Phenotypic and functional differences between human liver cancer endothelial cells and liver sinusoidal endothelial cells. Journal of Vascular Research, 45(1), 78-86. [More Information]
• Penet, M., Abou-Hamdan, M., Coltel, N., Cornille, E., Grau, G., de Reggi, M., Gharib, B. (2008). Protection against cerebral malaria by the low-molecular-weight thiol pantethine. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(4), 1321-1326. [More Information]
• Ramaswamy, Y., Wu, C., Van Hummel, A., Combes, V., Grau, G., Zreiqat, H. (2008). The responses of osteoblasts, osteoclasts and endothelial cells to zirconium modified calcium-silicate-based ceramic. Biomaterials, 29(33), 4392-4402. [More Information]
• Bechah, Y., Capo, C., Grau, G., Raoult, D., Mege, J. (2007). A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. Microbes and Infection, 9(7), 898-906. [More Information]
• Delahaye, N., Coltel, N., Puthier, D., Barbier, M., Benech, P., Joly, F., Iraqi, F., Grau, G., Nguyen, C., Rihet, P. (2007). Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. BMC Genomics, 8(452), 1-16. [More Information]
• Penet, M., Kober, F., Confort-Gouny, S., Le Fur, Y., Dalmasso, C., Coltel, N., Liprandi, A., Gulian, J., Grau, G., Cozzone, P., et al (2007). Magnetic Resonance Spectroscopy Reveals an Impaired Brain Metabolic Profile in Mice Resistant to Cerebral Malaria Infected with Plasmodium berghei ANKA. Journal of Biological Chemistry, 282(19), 14505-14514. [More Information]
• Togbe, D., Schofield, L., Grau, G., Schnyder, B., Boissay, V., Charron, S., Rose, S., Beutler, B., Quesniaux, V., Ryffel, B. (2007). Murine cerebral malaria development is independent of Toll-like receptor signaling. The American Journal of Pathology, 170(5), 1640-1648. [More Information]
• Niu, J., Zhang, W., Ye, L., Wu, L., Zhu, G., Yang, Z., Grau, G., Lou, J. (2007). The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion. European Journal of Cancer Prevention, 16(6), 517-527. [More Information]
• van der Heyde, H., Nolan, J., Combes, V., Gramaglia, I., Grau, G. (2006). A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends in Parasitology, 22(11), 503-508. [More Information]
• Meghari, S., Rolain, J., Grau, G., Platt, E., Barrassi, L., Mege, J., Raoult, D. (2006). Antiangiogenic Effect of Erythromycin: An In Vitro Model of Bartonella quintana Infection. The Journal of Infectious Diseases, 193(3), 380-386. [More Information]
• Hunt, N., Grau, G. (2006). Blood-brain barrier in parasitic disease. International Journal for Parasitology, 36(5), 503-504. [More Information]
• Coltel, N., Combes, V., Grau, G., Wassmer, S., Chimini, G. (2006). Cell vesiculation and immunopathology: implications in cerebral malaria. Microbes and Infection, 8(8), 2305-2316. [More Information]
• Combes, V., Coltel, N., Faille, D., Wassmer, S., Grau, G. (2006). Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier. International Journal for Parasitology, 36(5), 541-546. [More Information]
• Meghari, S., Desnues, B., Capo, C., Grau, G., Raoult, D., Mege, J. (2006). Coxiella burneti stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever. European Cytokine Network (Online), 17(4), 253-259.
• Golenser, J., Waknine, J., Krugliak, M., Hunt, N., Grau, G. (2006). Current perspectives on the mechanism of action of artemisinins. International Journal for Parasitology, 36(14), 1427-1441. [More Information]
• Peyrefitte, C., Pastorino, B., Grau, G., Lou, J., Tolou, H., Couissinier-Paris, P. (2006). Dengue virus infection of human microvascular endothelial cells from different vascular beds promotes both common and specific functional changes. Journal of Medical Virology, 78(2), 229-242. [More Information]
• Delahaye, N., Coltel, N., Puthier, D., Flori, L., Houlgate, R., Iraqi, F., Nguyen, C., Grau, G., Rihet, P. (2006). Gene-Expression Profiling Discriminates between Cerebral Malaria (CM)–Susceptible Mice and CM-Resistant Mice. The Journal of Infectious Diseases, 193, 312-321. [More Information]
• Wassmer, S., Cianciolo, G., Combes, V., Grau, G. (2006). LMP-420, a new therapeutic approach for cerebral malaria? Medecine Sciences, 22(4), 343-345.
• Zhang, W., Ye, L., Wu, L., Xin, Y., Gu, F., Niu, J., Yang, Z., Zhu, G., Grau, G., Lou, J. (2006). Morphologic, Phenotypic and Functional Characteristics of Endothelial Cells Derived from Human Hepatic Cavernous Hemangioma. Journal of Vascular Research, 43(6), 522-532. [More Information]
• Schofield, L., Grau, G. (2006). Oversimplification of the role of immunological processes in the pathogenesis of malaria - Author reply. Nature Reviews Immunology, 6(5).
• Wassmer, S., Combes, V., Candal, F., Juhan-Vague, I., Grau, G. (2006). Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum. Infection and Immunity, 74(1), 645-653. [More Information]
• Wassmer, S., De Souza, J., Frère, C., Candal, F., Juhan-Vague, I., Grau, G. (2006). TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. The Journal of Immunology, 176(2), 1180-1804. [More Information]
• Combes, V., Coltel, N., Alibert, M., van Eck, M., Raymond, C., Juhan-Vague, I., Grau, G., Chimini, G. (2005). ABCA1 Gene Deletion Protects against Cerebral Malaria: Potential Pathogenic Role of Microparticles in Neuropathology. The American Journal of Pathology, 166(1), 295-302. [More Information]
• Combes, V., De Souza, J., Rénia, L., Hunt, N., Grau, G. (2005). Cerebral malaria: Which parasite? Which model? Drug Discovery Today: Disease Models, 2(2), 141-147. [More Information]
• Penet, M., Viola, A., Confort-Gouny, S., Le Fur, Y., Duhamel, G., Kober, F., Ibarrola, D., Izquierdo, M., Coltel, N., Gharib, B., Grau, G., et al (2005). Imaging Experimental Cerebral Malaria In Vivo: Significant Role of Ischemic Brain Edema. The Journal of Neuroscience, 25(32), 7352-7358. [More Information]
• Schofield, L., Grau, G. (2005). Immunological processes in malaria pathogenesis. Nature Reviews Immunology, 5(9), 722-735. [More Information]
• Grau, G., Chimini, G. (2005). Immunopathological consequences of the loss of engulfment genes: the case of ABCA1. Societe de Biologie. Journal, 199(3), 199-206. [More Information]
• Wassmer, S., Cianciolo, G., Combes, V., Grau, G. (2005). Inhibition of Endothelial Activation: A New Way to Treat Cerebral Malaria? PLoS Medicine, 2(9), 885-890. [More Information]
• Coltel, N., Combes, V., Hunt, N., Grau, G. (2004). Cerebral Malaria - A Neurovascular Pathology with Many Riddles Still to be Solved. Current Neurovascular Research, 1(2), 91-110.
• Combes, V., Taylor, T., Juhan-Vague, I., Mege, J., Mwenechanya, J., Tembo, M., Grau, G., Molyneux, M. (2004). Circulating Endothelial Microparticles in Malawian Children With Severe Falciparum Malaria Complicated With Coma. JAMA: The Journal of the American Medical Association, 291(21), 2542-2544.
• Combes, V., Rosenkranz, A., Redard, M., Pizzolato, G., Lepidi, H., Vestweber, D., Mayadas, T., Grau, G. (2004). Pathogenic Role of P-Selectin in Experimental Cerebral Malaria. The American Journal of Pathology, 164(3), 781-786.
• Wassmer, S., Lepolard, C., Traore, B., Pouvelle, B., Gysin, J., Grau, G. (2004). Platelets Reorient Plasmodium falciparum–Infected Erythrocyte Cytoadhesion to Activated Endothelial Cells. The Journal of Infectious Diseases, 189(2), 180-189. [More Information]
• Rogerson, S., Grau, G., Hunt, N. (2004). The Microcirculation In Severe Malaria. Microcirculation, 11(7), 559-576. [More Information]
• Hunt, N., Grau, G. (2003). Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends in Immunology, 24(9), 491-499. [More Information]
• Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenesis of cerebral malaria: facts and hypotheses. Medecine Tropicale, 63(3), 254-257.
• Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenèse du Neuropaludisme: faits et hypothèses. Revista da Sociedade Brasileira de Medicina Tropical (RSBMT), (63), 254-257.
• Wassmer, S., Combes, V., Grau, G. (2003). Pathophysiology of Cerebral Malaria: Role of host cells in the modulation of cytoadhesion. Annals of the New York Academy of Sciences, 992, 30-38.
• Grau, G., Mackenzie, C., Carr, R., Redard, M., Pizzolato, G., Allasia, C., Cataldo, C., Taylor, T., Molyneux, M. (2003). Platelet Accumulation in Brain Microvessels in Fatal Pediatric Cerebral Malaria. The Journal of Infectious Diseases, 187(3), 461-466. [More Information]
• Lucas, R., Grau, G., Matthay, M., Wendel, A. (2002). Functional dissection of Tumour Necrosis Factor in liver, brain and lungs. Trends in Immunology, (3), 47-59.
• Dou, L., Cerini, C., Brunet, P., Guilianelli, C., Moal, V., Grau, G., De Smet, R., Vanholder, R., Sampol, J., Berland, Y. (2002). P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney International, 62(6), 1999-2009.
• Hamacher, J., Lucas, R., Lijnen, H., Buschke, S., Dunant, Y., Wendel, A., Grau, G., Suter, P., Ricou, B. (2002). Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 166(5), 651-656.
• Lucas, R., Montesano, R., Pepper, M., Hafner, M., Sablon, E., Dunant, Y., Grau, G., De Baetselier, P., Mannel, D., Fransen, L. (2001). Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. International Journal of Cancer, 91(4), 543-549.
• Lou, J., Lucas, R., Grau, G. (2001). Pathogenesis of Cerebral Malaria: Recent Experimental Data and Possible Applications for Humans. Clinical Microbiology Reviews, 14(4), 810-820.
• Stoelcker, B., Hehlgans, T., Weigl, K., Bluethmann, H., Grau, G., Mannel, D. (2001). Requirement for tumour necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria. Infection and Immunity, 70(10), 5857-5859.
• Harbarth, S., Holeckova, K., Froidevaux, C., Pittet, D., Ricou, B., Grau, G., Vadas, L., Pugin, J. (2001). Usefulness of procalcitonin, interleukin (IL)-6 and IL-8 in critically ill patients admitted with suspected sepsis. American Journal of Respiratory and Critical Care Medicine, 164(3), 396-402.

Conferences

• Lee, J., Carter, E., Grau, G., Combes, V., Bonhoure, B., Lay, P. (2009). The investigation of monocyte cell signalling by FT-IR spectroscopy. International Conference on Advanced Vibrational Spectroscopy, N/A: N/A.

Patents

• Hackett, M., Lay, P., Carter, E., Hunt, N., Grau, G., Gottlieb, D. (2010). Classification of biological samples using spectroscopic analysis. Patent No. WO2009AU01423 20091030.

2017

• Marzook, N., Latham, S., Lynn, H., McKenzie, C., Chaponnier, C., Grau, G., Newsome, T. (2017). Divergent roles of beta- and gamma-actin isoforms during spread of vaccinia virus. Cytoskeleton, 74(4), 170-183. [More Information]
• Maknitikul, S., Luplertlop, N., Grau, G., Ampawong, S. (2017). Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin. PloS One, 12(7), 1-22. [More Information]
• Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B, 187(2), 353-360. [More Information]
• Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B, 187(2), 353-360. [More Information]
• Claser, C., De Souza, J., Thorburn, S., Grau, G., Riley, E., Renia, L., Hafalla, J. (2017). Host resistance to Plasmodium-induced acute immune pathology is regulated by IL-10 receptor signalling. Infection and Immunity, 85(6), 1-9. [More Information]
• Lee, J., Wen, B., Carter, E., Combes, V., Grau, G., Lay, P. (2017). Infrared spectroscopic characterization of monocytic microvesicles (microparticles) released upon lipopolysaccharide stimulation. The FASEB Journal, 31(7), 2817-2827. [More Information]
• Gramaglia, I., Velez, J., Combes, V., Grau, G., Wree, M., van der Heyde, H. (2017). Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response. Blood, 129(12), 1669-1679. [More Information]
• Wassmer, S., Grau, G. (2017). Severe malaria: what's new on the pathogenesis front? International Journal for Parasitology, 47(42796), 145-152. [More Information]
• Zhao, Y., Ting, K., Li, J., Cogger, V., Chen, J., Johansson-Percival, A., Ngiow, S., Holst, J., Grau, G., Goel, S., McCaughan, G., Vadas, M., Gamble, J., et al (2017). Targeting vascular endothelial-cadherin in tumor-associated blood vessels promotes T-cell-mediated immunotherapy. Cancer Research, 77(16), 4434-4447. [More Information]
• Ghadiri, M., Young, P., Jarolimek, W., Grau, G., Oliver, B., Traini, D. (2017). The effect of non-specific tight junction modulators on the transepithelial transport of poorly permeable drugs across airway epithelial cells. Journal of Drug Targeting, 25(4), 342-349. [More Information]
• Hunt, N., Too, L., Khaw, L., Guo, J., Hee, L., Mitchell, A., Grau, G., Ball, H. (2017). The kynurenine pathway and parasitic infections that affect CNS function. Neuropharmacology, 112(Pt B), 389-398. [More Information]

2016

• O'Regan, N., Gegenbauer, K., O'Sullivan, J., Maleki, S., Brophy, T., Dalton, N., Chion, A., Fallon, P., Grau, G., Budde, U., et al (2016). A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood, 127(9), 1192-1201. [More Information]
• Sorrell, T., Juillard, P., Djordjevic, J., Kaufman-Francis, K., Dietmann, A., Milonig, A., Combes, V., Grau, G. (2016). Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var grubii strain H99 and C gattii strain R265. Microbes and Infection, 18(1), 57-67. [More Information]
• Combes, V., Latham, S., Wen, B., Allison, A., Grau, G. (2016). DIANNEXIN DOWN-MODULATES TNF-INDUCED ENDOTHELIAL MICROPARTICLE RELEASE BY BLOCKING MEMBRANE BUDDING PROCESS. International Journal of Medical and Health Sciences, 7, 1-11.
• Ghadiri, M., Mamlouk, M., Spicer, P., Jarolimek, W., Grau, G., Young, P., Traini, D. (2016). Effect of polyunsaturated fatty acids (PUFAs) on airway epithelial cells' tight junction. Pulmonary Pharmacology and Therapeutics, 40, 30-38. [More Information]
• Tiberti, N., Latham, S., Bush, S., Cohen, A., Opoka, R., John, C., Juillard, A., Grau, G., Combes, V. (2016). Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content. Scientific Reports, 6, 1-15. [More Information]
• Zinger, A., Latham, S., Combes, V., Byrne, S., Barnett, M., Hawke, S., Grau, G. (2016). Plasma levels of endothelial and B-cell-derived microparticles are restored by fingolimod treatment in multiple sclerosis patients. Multiple Sclerosis Journal, 22(14), 1883-1887. [More Information]
• Wassmer, S., Grau, G. (2016). Platelets as pathogenetic effectors and killer cells in cerebral malaria. Expert Review of Hematology, 9(6), 515-517. [More Information]
• Carvalho, T., Morahan, B., John von Freyenda, S., Boeuf, P., Grau, G., Garcia-Bustosa, J., Doerig, C. (2016). The ins and outs of phosphosignalling in Plasmodium: Parasite regulation and host cell manipulation. Molecular and Biochemical Parasitology, 208(1), 2-15. [More Information]
• Li, J., Zhao, Y., Lu, Y., Ritchie, W., Grau, G., Vadas, M., Gamble, J. (2016). The Poly-cistronic miR-23-27-24 complexes target endothelial cell junctions: differential functional and molecular effects of miR-23a and miR-23b. Molecular Therapy - Nucleic Acids, 5(8), 1-12. [More Information]

2015

• Ampawong, S., Chaisri, U., Viriyavejakul, P., Prapansilp, P., Grau, G., Turner, G., Pongponratn, E. (2015). A potential role for interleukin-33 and γ-epithelium sodium channel in the pathogenesis of human malaria associated lung injury. Malaria Journal, 14(1), 1-15. [More Information]
• Bucur, O., Almasan, A., Zubarev, R., Friedman, M., Nicolson, G., Sumazin, P., Leabu, M., Nikolajczyk, B., Avram, D., Kunej, T., Richardson, D., Grau, G., et al (2015). An updated h-index measures both the primary and total scientific output of a researcher. Discoveries, 3(3), 1-6. [More Information]
• Kam, A., Li, K., Razmovski-Naumovsk, V., Nammi, S., Chan, K., Grau, G., Li, G. (2015). Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells. Journal of Pharmacy and Pharmaceutical Sciences, 18(4), 424-433. [More Information]
• Hochman, S., Madaline, T., Wassmer, S., Mbale, E., Choi, N., Seydel, K., Whitten, R., Varughese, J., Grau, G., Kamiza, S., et al (2015). Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. MBIO, 6(5), 1-12. [More Information]
• Latham, S., Tiberti, N., Gokoolparsadh, N., Holdaway, K., Couraud, P., Grau, G., Combes, V. (2015). Immuno-analysis of microparticles: probing at the limits of detection. Scientific Reports, 5, 1-13. [More Information]
• Hackett, M., Aitken, J., El Assaad, F., McQuillan, J., Carter, E., Ball, H., Tobin, M., Paterson, D., De Jonge, M., Siegele, R., Grau, G., Hunt, N., Lay, P., et al (2015). Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites. Science Advances, 6(4), 7-16. [More Information]
• Cohen, A., Combes, V., Grau, G. (2015). MicroRNAs and Malaria – A Dynamic Interaction Still Incompletely Understood. Journal of Neuroinfectious Diseases, 6(1), 1-12. [More Information]
• Whittington, C., Grau, G., Murphy, C., Thompson, M. (2015). Unusual angiogenic factor plays a role in lizard pregnancy but is not unique to viviparity. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 324B (2), 152-158. [More Information]
• Danastas, K., Combes, V., Lindsay, L., Grau, G., Thompson, M., Murphy, C. (2015). VEGF111: New insights in tissue invasion. Frontiers in Physiology, 6, 1-5. [More Information]
• Grau, G., Thompson, M., Murphy, C. (2015). VEGF: Inflammatory paradoxes. Pathogens and Global Health, 109(6), 253-254. [More Information]

2014

• Khaw, L., Ball, H., Mitchell, A., Grau, G., Stocker, R., Golenser, J., Hunt, N. (2014). Brain endothelial cells increase the proliferation of Plasmodium falciparum through production of soluble factors. Experimental Parasitology, 145(1), 34-41. [More Information]
• Jaiswal, R., Grau, G., Bebawy, M. (2014). Cellular communication via microparticles: role in transfer of multidrug resistance in cancer. Future Oncology, 10(4), 655-669. [More Information]
• Hunt, N., Ball, H., Hansen, A., Khaw, L., Guo, J., Bakmiwewa, S., Mitchell, A., Combes, V., Grau, G. (2014). Cerebral malaria: gamma-interferon redux. Frontiers in Cellular and Infection Microbiology, 4, 1-12. [More Information]
• Grau, G., Hunt, N. (2014). Cytokines and Some of Their Effector Mechanisms in Cerebral Malaria Pathogenesis. In M. Hommel and P. G. Kremsner (Eds.), Encyclopedia of Malaria, (pp. 1-11). New York: Springer. [More Information]
• Ampawong, S., Chaisri, U., Viriyavejakul, P., Nontprasert, A., Grau, G., Pongponratn, E. (2014). Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression. International Journal of Clinical and Experimental Pathology, 7(5), 2056-2067.
• Wheway, J., Latham, S., Combes, V., Grau, G. (2014). Endothelial Microparticles Interact with and Support the Proliferation of T Cells. The Journal of Immunology, 193(7), 3378-3387. [More Information]
• Wen, B., Combes, V., Bonhoure, A., Weksler, B., Couraud, P., Grau, G. (2014). Endotoxin-Induced Monocytic Microparticles Have Contrasting Effects on Endothelial Inflammatory Responses. PloS One, 9(3), e91597. [More Information]
• El-Assaad, F., Combes, V., Grau, G., Jambou, R. (2014). Potential Efficacy of Citicoline as Adjunct Therapy in Treatment of Cerebral Malaria. Antimicrobial Agents and Chemotherapy, 58(1), 602-605. [More Information]
• El Assaad, F., Wheway, J., Hunt, N., Grau, G., Combes, V. (2014). Production, fate and pathogenicity of plasma microparticles in murine cerebral malaria. PLoS Pathogens, 10(3), 1-14. [More Information]
• Pai, S., Qin, J., Cavanagh, L., Mitchell, A., El-Assaad, F., Jain, R., Combes, V., Hunt, N., Grau, G., Weninger, W. (2014). Real-Time Imaging Reveals the Dynamics of Leukocyte Behaviour during Experimental Cerebral Malaria Pathogenesis. PLoS Pathogens, 10(7), 1-17. [More Information]

2013

• Jaiswal, R., Luk, F., Dalla, P., Grau, G., Debawy, M. (2013). Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells. PloS One, 8(4), 1-10. [More Information]
• Roseblade, A., Luk, F., Rawling, T., Ung, A., Grau, G., Bebawy, M. (2013). Cell-Derived Microparticles: New Targets in the Therapeutic Management of Disease. Journal of Pharmacy and Pharmaceutical Sciences, 16(2), 238-253. [More Information]
• Latham, S., Chaponnier, C., Dugina, V., Couraud, P., Grau, G., Combes, V. (2013). Cooperation between beta- and gamma-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. The FASEB Journal, 27(2), 672-683. [More Information]
• Razakandrainibe, R., Combes, V., Grau, G., Jambou, R. (2013). Crossing the wall: The opening of endothelial cell junctions during infectious diseases. The International Journal of Biochemistry and Cell Biology, 45(7), 1165-1173. [More Information]
• El-Assaad, F., Wheway, J., Mitchell, A., Lou, J., Hunt, N., Combes, V., Grau, G. (2013). Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infection and Immunity, 81(11), 3984-3991. [More Information]
• Dietmann, A., Millonig, A., Combes, V., Couraud, P., Kachlany, S., Grau, G. (2013). Effects of aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells. Microbial Pathogenesis, 61 - 62, 43-50. [More Information]
• Khaw, L., Ball, H., Golenser, J., Combes, V., Grau, G., Wheway, J., Mitchell, A., Hunt, N. (2013). Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria. PloS One, 8(7), 1-13. [More Information]
• Li, C., Eaton, S., Young, P., Lee, M., Shuttleworth, R., Humphreys, D., Grau, G., Combes, V., Bebawy, M., Gong, J., Buckland, M., et al (2013). Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biology, 10(8), 1333-1344. [More Information]
• Lee, J., Siegele, R., Pastuovic, Z., Hackett, M., Hunt, N., Grau, G., Cohen, D., Lay, P. (2013). Light and heavy ion beam analysis of thin biological sections. Nuclear Instruments and Methods in Physics Research B, 306, 129-133. [More Information]
• Gong, J., Luk, F., Jaiswal, R., George, A., Grau, G., Bebawy, M. (2013). Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance. European Journal of Pharmacology, 721(1-3), 116-125. [More Information]
• Walters, S., Kieckbusch, J., Nagalingam, G., Swain, A., Latham, S., Grau, G., Britton, W., Combes, V., Saunders, B. (2013). Microparticles from Mycobacteria-Infected Macrophages Promote Inflammation and Cellular Migration. The Journal of Immunology, 190(2), 669-677. [More Information]
• Lu, J., Luk, F., Gong, J., Jaiswal, R., Grau, G., Bebawy, M. (2013). Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways. Pharmacological Research, 76, 77-83. [More Information]
• Liu, H., Zhang, W., Jia, Y., Yu, Q., Grau, G., Peng, L., Ran, Y., Yang, Z., Deng, H., Lou, J. (2013). Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death and Disease, 4(10), 1-11. [More Information]
• Wheway, J., Obeid, S., Couraud, P., Combes, V., Grau, G. (2013). The brain microvascular endothelium supports t cell proliferation and has potential for alloantigen presentation. PloS One, 8(1), 1-8. [More Information]

2012

• Razakandrainibe, R., Pelleau, S., Grau, G., Jambou, R. (2012). Antigen presentation by endothelial cells: what role in the pathophysiology of malaria? Trends in Parasitology, 28(4), 151-160. [More Information]
• Grau, G., Craig, A. (2012). Cerebral malaria pathogenesis: revisiting parasite and host contributions. Future Microbiology, 7(2), 291-302. [More Information]
• Faille, D., El Assaad, F., Mitchell, A., Alessi, M., Chimini, G., Fusai, T., Grau, G., Combes, V. (2012). Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells. Journal of Cellular and Molecular Medicine, 16(8), 1731-1738. [More Information]
• Hackett, M., Lee, J., El Assaad, F., McQuillan, J., Carter, E., Grau, G., Hunt, N., Lay, P. (2012). FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: General implications for disease neurochemistry. ACS Chemical Neuroscience, 3(12), 1017-1024. [More Information]
• Jaiswal, R., Luk, F., Gong, J., Mathys, J., Grau, G., Bebawy, M. (2012). Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Molecular Cancer, 11, 1-13. [More Information]
• Jaiswal, R., Gong, J., Sambasivam, S., Combes, V., Mathys, J., Davey, R., Grau, G., Bebawy, M. (2012). Microparticle-associated nucleic acids mediate trait dominance in cancer. The FASEB Journal, 26(1), 420-429. [More Information]
• Gong, J., Jaiswal, R., Mathys, J., Combes, V., Grau, G., Bebawy, M. (2012). Microparticles and their emerging role in cancer multidrug resistance. Cancer Treatment Reviews, 38(3), 226-234. [More Information]
• Combes, V., Guillemin, G., Chan-Ling, T., Hunt, N., Grau, G. (2012). The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. Trends in Parasitology, 28(8), 311-319. [More Information]
• Hafalla, J., Claser, C., Couper, K., Grau, G., Renia, L., De Souza, J., Riley, E. (2012). The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathogens, 8(2), 1-12. [More Information]
• Craig, A., Grau, G., Janse, C., Kazura, J., Milner, D., Barnwell, J., Turner, G., Langhorne, J. (2012). The Role of Animal Models for Research on Severe Malaria. PLoS Pathogens, 8(2), 1-9. [More Information]

2011

• Hackett, M., McQuillan, J., El Assaad, F., Aitken, J., Levina, A., Cohen, D., Siegele, R., Carter, E., Grau, G., Hunt, N., Lay, P. (2011). Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. The Analyst, 136(14), 2941-2952. [More Information]
• Nantakomol, D., Dondorp, A., Krudsood, S., Udomsangpetch, R., Pattanapanyasat, K., Combes, V., Grau, G., White, N., Viriyavejakul, P., Day, N., et al (2011). Circulating red cell-derived microparticles in human malaria. The Journal of Infectious Diseases, 203(5), 700-706. [More Information]
• Hempel, C., Combes, V., Hunt, N., Kurtzhals, J., Grau, G. (2011). CNS Hypoxia Is More Pronounced in Murine Cerebral than Noncerebral Malaria and is Reversed by Erythropoietin. The American Journal of Pathology, 179(4), 1939-1950. [More Information]
• McQuillan, J., Mitchell, A., Ho, Y., Combes, V., Ball, H., Golenser, J., Grau, G., Hunt, N. (2011). Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. International Journal for Parasitology, 41(2), 155-163. [More Information]
• El Assaad, F., Hempel, C., Combes, V., Mitchell, A., Ball, H., Kurtzhals, J., Hunt, N., Mathys, J., Grau, G. (2011). Differential MicroRNA Expression in Experimental Cerebral and Noncerebral Malaria. Infection and Immunity, 79(6), 2379-2384. [More Information]
• Combes, V., El-Assaad, F., Grau, G. (2011). Immunopathology and pathophysiology of cerebral malaria. In Mauro Bendinelli, Herman Friedman and Andreas Seyfang (Eds.), Infectious Agents and Pathogenesis. tba: Springer Publishing Company.
• Saggu, R., Faille, D., Grau, G., Cozzone, P., Viola, A. (2011). In the eye of experimental cerebral malaria. The American Journal of Pathology, 179(3), 1104-1109. [More Information]
• Jambou, R., El Assaad, F., Combes, V., Grau, G. (2011). In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria. Malaria Journal, 10(1), A346-1-A346-5. [More Information]
• Hackett, M., Siegele, R., El Assaad, F., McQuillan, J., Aitken, J., Carter, E., Grau, G., Hunt, N., Cohen, D., Lay, P. (2011). Investigation of the mouse cerebellum using STIM and μ-PIXE spectrometric and FTIR spectroscopic mapping and imaging. Nuclear Instruments and Methods in Physics Research B, 269(20), 2260-2263. [More Information]
• Moxon, C., Grau, G., Craig, A. (2011). Malaria: modification of the red blood cell and consequences in the human host. British Journal of Haematology, 154(6), 670-679. [More Information]
• Ling, Z., Combes, V., Grau, G., King, N. (2011). Microparticles as immune regulators in infectious disease - an opinion. Frontiers in Immunology, 2(67), 1-8. [More Information]
• Barbier, M., Faille, D., Loriod, B., Textoris, J., Camus, C., Puthier, D., Flori, L., Wassmer, S., Victorero, G., Alessi, M., Grau, G., et al (2011). Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria. PloS One, 6(5), e19651-1-e19651-14. [More Information]
• Ampawong, S., Combes, V., Hunt, N., Radford, J., Chan-Ling, T., Pongponratn, E., Grau, G. (2011). Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. International Journal of Clinical and Experimental Pathology, 4(6), 566-574. [More Information]
• Hee, L., Dinudom, A., Mitchell, A., Grau, G., Cook, D., Hunt, N., Ball, H. (2011). Reduced activity of the epithelial sodium channel in malaria-induced pulmonary oedema in mice. International Journal for Parasitology, 41(1), 81-88. [More Information]
• Wassmer, S., Moxon, C., Taylor, T., Grau, G., Molyneux, M., Craig, A. (2011). Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cellular Microbiology Online, 13(2), 198-209. [More Information]

2010

• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Combes, V., Grau, G., Amvam Zollo, P. (2010). Biochemical markers of nutritional status and childhood malaria severity in Cameroon. British Journal of Nutrition, 104(6), 886-892. [More Information]
• Hackett, M., Lay, P., Carter, E., Hunt, N., Grau, G., Gottlieb, D. (2010). Classification of biological samples using spectroscopic analysis. Patent No. WO2009AU01423 20091030.
• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Amvam Zollo, P., Grau, G., Combes, V. (2010). Elevated Cell-Specific Microparticles Are a Biological Marker for Cerebral Dysfunctions in Human Severe Malaria. PloS One, 5(10), e13415 - 1-e13415 - 9. [More Information]
• Carpintero, R., Gruaz, L., Brandt, K., Scanu, A., Faille, D., Combes, V., Grau, G., Burger, D. (2010). HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production. PloS One, 5(7), e11869-1-e11869-8. [More Information]
• Combes, V., El-Assaad, F., Faille, D., Jambou, R., Hunt, N., Grau, G. (2010). Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Progress in Neurobiology, 91(2), 140-151. [More Information]
• Hunt, N., Grau, G., Engwerda, C., Barnum, S., van der Heyde, H., Hansen, D., Schofield, L., Golenser, J. (2010). Murine cerebral malaria: the whole story. Trends in Parasitology, 26(6), 272-4. [More Information]
• Couper, K., Barnes, T., Hafalla, J., Combes, V., Ryffel, B., Secher, T., Grau, G., Riley, E., De Souza, J. (2010). Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation. PLoS Pathogens, 6(1), e1000744-1-e1000744-13. [More Information]
• Jambou, R., Combes, V., Mege-Jambou, M., Weksler, B., Couraud, P., Grau, G. (2010). Plasmodium falciparum Adhesion on Human Brain Microvascular Endothelial Cells Involves Transmigration-Like Cup Formation and Induces Opening of Intercellular Junctions. PLoS Pathogens, 6(7), 1-13. [More Information]
• Bridges, D., Bunn, J., Van Mourik, J., Grau, G., Preston, R., Molyneux, M., Combes, V., O'Donnell, J., De Laat, B., Craig, A. (2010). Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings. Blood, 115(7), 1472-1474. [More Information]
• Mitchell, A., Pradel, L., Chasson, L., Van Rooijen, N., Grau, G., Hunt, N., Chimini, G. (2010). Technical Advance: Autofluorescence as a tool for myeloid cell analysis. Journal of Leukocyte Biology, 88(3), 597-603. [More Information]

2009

• Zhang, W., Wu, L., Liu, H., Ye, L., Xin, Y., Grau, G., Lou, J. (2009). Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation. Microvascular research, 78(3), 379-385. [More Information]
• El-Assaad, F., Combes, V., Grau, G. (2009). Citicoline (CDP-choline): What role in the treatment of complications of infectious diseases. The International Journal of Biochemistry and Cell Biology, 41(7), 1467-1470. [More Information]
• Bruzzone, R., Dubois-Dalcq, M., Grau, G., Griffin, D., Kristensson, K. (2009). Infectious diseases of the nervous system and their impact in developing countries. PLOS Pathogens, 5(2), e1000199. [More Information]
• Bebawy, M., Combes, V., Lee, E., Jaiswal, R., Gong, J., Bonhoure, A., Grau, G. (2009). Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells. Leukemia, 23(9), 1643-1649. [More Information]
• Gouado, I., Pankoui Mfonkeu, J., Fotso, H., Zambou, O., Nguele, S., Combes, V., Grau, G., Amvam Zollo, P. (2009). Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon. The Pediatric Infectious Disease Journal, 28(12), 1081-1084. [More Information]
• Faille, D., Combes, V., Mitchell, A., Fontaine, A., Juhan-Vague, I., Alessi, M., Chimini, G., Fusai, T., Grau, G. (2009). Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium. The F A S E B Journal, 23(10), 3449-3458. [More Information]
• Faille, D., El Assaad, F., Alessi, M., Fusai, T., Combes, V., Grau, G. (2009). Platelet-endothelial cell interactions in cerebral malaria: The end of a cordial understanding. Thrombosis and Haemostasis, 102(6), 1093-1102. [More Information]
• Bechah, Y., Capo, C., Grau, G., Raoult, D., Mege, J. (2009). Rickettsia prowazekii infection of endothelial cells increases leukocyte adhesion through alpha (v)beta(3) integrin engagement. Clinical Microbiology and Infection, 15(Suppl 2), 249-250. [More Information]
• Larkin, D., de Laat, M., Jenkins, P., Bunn, J., Craig, A., Terraube, V., Preston, R., Donkor, C., Grau, G., Van Mourik, J., et al (2009). Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. PLoS Pathogens, 5(3), 1-8. [More Information]
• Lee, J., Carter, E., Grau, G., Combes, V., Bonhoure, B., Lay, P. (2009). The investigation of monocyte cell signalling by FT-IR spectroscopy. International Conference on Advanced Vibrational Spectroscopy, N/A: N/A.

2008

• von zur Muhlen, C., Sibson, N., Peter, K., Campbell, S., Wilainam, P., Grau, G., Bode, C., Choudhury, R., Anthony, D. (2008). A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI. Journal of Clinical Investigation, 118(3), 1198-1207. [More Information]
• Togbe, D., de Sousa, P., Fauconnier, M., Boissay, V., Fick, L., Scheu, S., Pfeffer, K., Menard, R., Grau, G., Doan, B., Hansen, A., Ball, H., Hunt, N., et al (2008). Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PloS One, 3(7), e2608-1-e2608-12. [More Information]
• Pankoui Mfonkeu, J., Gouado, I., Fotso Kuate, H., Zambou, O., Grau, G., Combes, V., Amvam Zollo, P. (2008). Clinical presentation, haematological indices and management of children with severe and uncomplicated malaria in Douala, Cameroon. Pakistan Journal of Biological Sciences, 11(20), 2401-2406. [More Information]
• Hunt, N., Mitchell, A., Hee, L., Xu, Y., Ho, Y., McQuillan, J., Sanchez-Perez, A., Miu, J., Weiser, S., Austin, C., Grau, G., Combes, V., Jambou, R., Ball, H. (2008). Early interactions between malaria-infected erythrocytes and the innate immune system determine the course of immune and immunopathological outcomes. International Journal for Parasitology, 38(Suppl 1), S23-S24. [More Information]
• Wu, L., Zhang, W., Niu, J., Ye, L., Yang, Z., Grau, G., Lou, J. (2008). Phenotypic and functional differences between human liver cancer endothelial cells and liver sinusoidal endothelial cells. Journal of Vascular Research, 45(1), 78-86. [More Information]
• Penet, M., Abou-Hamdan, M., Coltel, N., Cornille, E., Grau, G., de Reggi, M., Gharib, B. (2008). Protection against cerebral malaria by the low-molecular-weight thiol pantethine. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(4), 1321-1326. [More Information]
• Ramaswamy, Y., Wu, C., Van Hummel, A., Combes, V., Grau, G., Zreiqat, H. (2008). The responses of osteoblasts, osteoclasts and endothelial cells to zirconium modified calcium-silicate-based ceramic. Biomaterials, 29(33), 4392-4402. [More Information]

2007

• Bechah, Y., Capo, C., Grau, G., Raoult, D., Mege, J. (2007). A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. Microbes and Infection, 9(7), 898-906. [More Information]
• Delahaye, N., Coltel, N., Puthier, D., Barbier, M., Benech, P., Joly, F., Iraqi, F., Grau, G., Nguyen, C., Rihet, P. (2007). Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. BMC Genomics, 8(452), 1-16. [More Information]
• Penet, M., Kober, F., Confort-Gouny, S., Le Fur, Y., Dalmasso, C., Coltel, N., Liprandi, A., Gulian, J., Grau, G., Cozzone, P., et al (2007). Magnetic Resonance Spectroscopy Reveals an Impaired Brain Metabolic Profile in Mice Resistant to Cerebral Malaria Infected with Plasmodium berghei ANKA. Journal of Biological Chemistry, 282(19), 14505-14514. [More Information]
• Combes, V., Grau, G. (2007). Microvascular endothelium and cerebral malaria. In William Aird (Eds.), The Endothelium: A Comprehensive Reference. CRC Press.
• Togbe, D., Schofield, L., Grau, G., Schnyder, B., Boissay, V., Charron, S., Rose, S., Beutler, B., Quesniaux, V., Ryffel, B. (2007). Murine cerebral malaria development is independent of Toll-like receptor signaling. The American Journal of Pathology, 170(5), 1640-1648. [More Information]
• Combes, V., Lou, J., Grau, G. (2007). The endothelium in cerebral malaria - Both a target cell and a major player. In William Aird (Eds.), Endothelial Biomedicine, (pp. 1303-1310). United States: Cambridge University Press.
• Niu, J., Zhang, W., Ye, L., Wu, L., Zhu, G., Yang, Z., Grau, G., Lou, J. (2007). The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion. European Journal of Cancer Prevention, 16(6), 517-527. [More Information]

2006

• van der Heyde, H., Nolan, J., Combes, V., Gramaglia, I., Grau, G. (2006). A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends in Parasitology, 22(11), 503-508. [More Information]
• Meghari, S., Rolain, J., Grau, G., Platt, E., Barrassi, L., Mege, J., Raoult, D. (2006). Antiangiogenic Effect of Erythromycin: An In Vitro Model of Bartonella quintana Infection. The Journal of Infectious Diseases, 193(3), 380-386. [More Information]
• Hunt, N., Grau, G. (2006). Blood-brain barrier in parasitic disease. International Journal for Parasitology, 36(5), 503-504. [More Information]
• Coltel, N., Combes, V., Grau, G., Wassmer, S., Chimini, G. (2006). Cell vesiculation and immunopathology: implications in cerebral malaria. Microbes and Infection, 8(8), 2305-2316. [More Information]
• Combes, V., Coltel, N., Faille, D., Wassmer, S., Grau, G. (2006). Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier. International Journal for Parasitology, 36(5), 541-546. [More Information]
• Meghari, S., Desnues, B., Capo, C., Grau, G., Raoult, D., Mege, J. (2006). Coxiella burneti stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever. European Cytokine Network (Online), 17(4), 253-259.
• Golenser, J., Waknine, J., Krugliak, M., Hunt, N., Grau, G. (2006). Current perspectives on the mechanism of action of artemisinins. International Journal for Parasitology, 36(14), 1427-1441. [More Information]
• Combes, V., Grau, G. (2006). Cytokines in defence and pathology of the central nervous system. In Richard M. Ransohoff, Etty N. Benveniste (Eds.), Cytokines and the CNS - 2nd Edition, (pp. 243-268). United States: CRC Press.
• Peyrefitte, C., Pastorino, B., Grau, G., Lou, J., Tolou, H., Couissinier-Paris, P. (2006). Dengue virus infection of human microvascular endothelial cells from different vascular beds promotes both common and specific functional changes. Journal of Medical Virology, 78(2), 229-242. [More Information]
• Delahaye, N., Coltel, N., Puthier, D., Flori, L., Houlgate, R., Iraqi, F., Nguyen, C., Grau, G., Rihet, P. (2006). Gene-Expression Profiling Discriminates between Cerebral Malaria (CM)–Susceptible Mice and CM-Resistant Mice. The Journal of Infectious Diseases, 193, 312-321. [More Information]
• Wassmer, S., Cianciolo, G., Combes, V., Grau, G. (2006). LMP-420, a new therapeutic approach for cerebral malaria? Medecine Sciences, 22(4), 343-345.
• Zhang, W., Ye, L., Wu, L., Xin, Y., Gu, F., Niu, J., Yang, Z., Zhu, G., Grau, G., Lou, J. (2006). Morphologic, Phenotypic and Functional Characteristics of Endothelial Cells Derived from Human Hepatic Cavernous Hemangioma. Journal of Vascular Research, 43(6), 522-532. [More Information]
• Schofield, L., Grau, G. (2006). Oversimplification of the role of immunological processes in the pathogenesis of malaria - Author reply. Nature Reviews Immunology, 6(5).
• Wassmer, S., Combes, V., Candal, F., Juhan-Vague, I., Grau, G. (2006). Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum. Infection and Immunity, 74(1), 645-653. [More Information]
• Wassmer, S., De Souza, J., Frère, C., Candal, F., Juhan-Vague, I., Grau, G. (2006). TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. The Journal of Immunology, 176(2), 1180-1804. [More Information]

2005

• Combes, V., Coltel, N., Alibert, M., van Eck, M., Raymond, C., Juhan-Vague, I., Grau, G., Chimini, G. (2005). ABCA1 Gene Deletion Protects against Cerebral Malaria: Potential Pathogenic Role of Microparticles in Neuropathology. The American Journal of Pathology, 166(1), 295-302. [More Information]
• Combes, V., De Souza, J., Rénia, L., Hunt, N., Grau, G. (2005). Cerebral malaria: Which parasite? Which model? Drug Discovery Today: Disease Models, 2(2), 141-147. [More Information]
• Penet, M., Viola, A., Confort-Gouny, S., Le Fur, Y., Duhamel, G., Kober, F., Ibarrola, D., Izquierdo, M., Coltel, N., Gharib, B., Grau, G., et al (2005). Imaging Experimental Cerebral Malaria In Vivo: Significant Role of Ischemic Brain Edema. The Journal of Neuroscience, 25(32), 7352-7358. [More Information]
• Schofield, L., Grau, G. (2005). Immunological processes in malaria pathogenesis. Nature Reviews Immunology, 5(9), 722-735. [More Information]
• Grau, G., Chimini, G. (2005). Immunopathological consequences of the loss of engulfment genes: the case of ABCA1. Societe de Biologie. Journal, 199(3), 199-206. [More Information]
• Wassmer, S., Cianciolo, G., Combes, V., Grau, G. (2005). Inhibition of Endothelial Activation: A New Way to Treat Cerebral Malaria? PLoS Medicine, 2(9), 885-890. [More Information]

2004

• Coltel, N., Combes, V., Hunt, N., Grau, G. (2004). Cerebral Malaria - A Neurovascular Pathology with Many Riddles Still to be Solved. Current Neurovascular Research, 1(2), 91-110.
• Combes, V., Taylor, T., Juhan-Vague, I., Mege, J., Mwenechanya, J., Tembo, M., Grau, G., Molyneux, M. (2004). Circulating Endothelial Microparticles in Malawian Children With Severe Falciparum Malaria Complicated With Coma. JAMA: The Journal of the American Medical Association, 291(21), 2542-2544.
• Combes, V., Rosenkranz, A., Redard, M., Pizzolato, G., Lepidi, H., Vestweber, D., Mayadas, T., Grau, G. (2004). Pathogenic Role of P-Selectin in Experimental Cerebral Malaria. The American Journal of Pathology, 164(3), 781-786.
• Wassmer, S., Lepolard, C., Traore, B., Pouvelle, B., Gysin, J., Grau, G. (2004). Platelets Reorient Plasmodium falciparum–Infected Erythrocyte Cytoadhesion to Activated Endothelial Cells. The Journal of Infectious Diseases, 189(2), 180-189. [More Information]
• Rogerson, S., Grau, G., Hunt, N. (2004). The Microcirculation In Severe Malaria. Microcirculation, 11(7), 559-576. [More Information]

2003

• Hunt, N., Grau, G. (2003). Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends in Immunology, 24(9), 491-499. [More Information]
• Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenesis of cerebral malaria: facts and hypotheses. Medecine Tropicale, 63(3), 254-257.
• Wassmer, S., Coltel, N., Combes, V., Grau, G. (2003). Pathogenèse du Neuropaludisme: faits et hypothèses. Revista da Sociedade Brasileira de Medicina Tropical (RSBMT), (63), 254-257.
• Wassmer, S., Combes, V., Grau, G. (2003). Pathophysiology of Cerebral Malaria: Role of host cells in the modulation of cytoadhesion. Annals of the New York Academy of Sciences, 992, 30-38.
• Grau, G., Mackenzie, C., Carr, R., Redard, M., Pizzolato, G., Allasia, C., Cataldo, C., Taylor, T., Molyneux, M. (2003). Platelet Accumulation in Brain Microvessels in Fatal Pediatric Cerebral Malaria. The Journal of Infectious Diseases, 187(3), 461-466. [More Information]

2002

• Lucas, R., Grau, G., Matthay, M., Wendel, A. (2002). Functional dissection of Tumour Necrosis Factor in liver, brain and lungs. Trends in Immunology, (3), 47-59.
• Dou, L., Cerini, C., Brunet, P., Guilianelli, C., Moal, V., Grau, G., De Smet, R., Vanholder, R., Sampol, J., Berland, Y. (2002). P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney International, 62(6), 1999-2009.
• Hamacher, J., Lucas, R., Lijnen, H., Buschke, S., Dunant, Y., Wendel, A., Grau, G., Suter, P., Ricou, B. (2002). Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 166(5), 651-656.

2001

• Lucas, R., Montesano, R., Pepper, M., Hafner, M., Sablon, E., Dunant, Y., Grau, G., De Baetselier, P., Mannel, D., Fransen, L. (2001). Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. International Journal of Cancer, 91(4), 543-549.
• Lou, J., Lucas, R., Grau, G. (2001). Pathogenesis of Cerebral Malaria: Recent Experimental Data and Possible Applications for Humans. Clinical Microbiology Reviews, 14(4), 810-820.
• Stoelcker, B., Hehlgans, T., Weigl, K., Bluethmann, H., Grau, G., Mannel, D. (2001). Requirement for tumour necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria. Infection and Immunity, 70(10), 5857-5859.
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