License our intellectual property
Our portfolio of inventions and innovations spans a number of sectors, including diagnostics, therapeutics, biomedical devices and optical technology.
Transform pioneering research into impactful innovations through licensing, collaboration, and investment opportunities. Contact the Commercialisation Office.
Licensing Opportunities
Life sciences
A new gene editing technology that offers enhanced precision and the capability to insert large DNA sequences without off-target mutations or triggering error-prone DNA repair. Using IS1111/110 family members as a new gene editing technology (pdf, 131.7KB)
Inventors: Sandro F Ataide, Rezwan Siddiquee, Ruth Hall
Contact: taylor.syme@sydney.edu.au
Novel inhibitors that target the Two-Partner Secretion system, potentially blocking the secretion of virulence factors in Gram-negative bacteria, offering a new approach to combat bacterial infections.
Inventors: Matthew Thomas Doyle, Alfred Hartojo, Peggy Cotter, Richard Johnson
Contact: taylor.syme@sydney.edu.au
Urinary biomarker panel for the early detection of pancreatic cancer.
Inventors: Sumit Sahni, Bharat Venkatesh Gundappa, Anubhav Mittal, Jaswinder Samra
Contact: taylor.syme@sydney.edu.au
Blood biomarker panel for the early detection of pancreatic cancer.
Inventors: Sumit Sahni, Anubhav Mittal, Jaswinder Samra, Mark Molloy, Bharat Venkatesh Gundappa, Matthew J Mckay, Sooin Byeon
Contact: taylor.syme@sydney.edu.au
An antibody targeting Myc, with the potential to disrupt this otherwise "undruggable" target in various cancers.
Contact: taylor.syme@sydney.edu.au
A diagnostic tool that utilises mass cytometry to detect early stages of coronary artery disease (CAD) by identifying altered immune cell proportions in blood, improving patient outcomes by circumventing the risks of current diagnostic methods. An immune signature detectable by mass cytometry which correlates with the presence of detectable coronary artery disease (pdf, 138.6KB)
Inventors: Gemma Figtree, Katharine Kott, Ellis Patrick, Stuart Grieve, Jean Yang, Barbara Fazekas de St Groth, Helen McGuire, Adam Chan.
Contact: taylor.syme@sydney.edu.au
A rapid, home-use diagnostic platform for Inflammatory Bowel Disease management by measuring myeloperoxidase activity in faecal samples. Rapid fecal myeloperoxidase detection kit for patients with Inflammatory Bowel Disease (pdf, 165.2KB).
Inventors: Belal Chami, Paul Kenneth Witting
Contact: taylor.syme@sydney.edu.au
A molecular diagnostic solution with over 95% specificity, leveraging DNA sequencing to objectively differentiate melanoma from benign naevi, thereby reducing the subjectivity and variability of traditional histopathology. MIAdx Molecular Diagnostic Test of Melanocytic lesions (pdf, 203.1KB)
Inventors: Richard A. Scolyer, Georgina Long, Ismael A. V. Correa, Andrew Colebatch, James Wilmott
Contact: taylor.syme@sydney.edu.au
A minimally invasive method for measuring soft tissue tension, providing real-time surgical feedback. An optical instrumentation for load sensing in soft tissue (pdf, 184.2KB).
Inventors: Mounir Boudali, Elizabeth Clarke
Contact: taylor.syme@sydney.edu.au
Novel online platform offering a structured conversation skills training program for individuals with acquired brain injury and their clinicians. convers-ABI-lity - conversation skills training program for people with acquired brain injury (pdf, 97.8KB)
Inventors: Leanne Togher, Rachael Rietdijk, Emma Power, Renee Lim, Melissa Brunner, Petra Avramovic, Melissa Ian-Ai Miao, Jarryd Daymond, Steven Maguire
Contact: emma-louise.hunsley@sydney.edu.au
A PSA-activated peptide sequence for prodrugs that enables targeted therapy for prostate cancer. A new approach for precision therapy for prostate cancer (pdf, 124.7KB).
Inventors: Trevor Hambley, Elisabeth Tondl
Contact: emma-louise.hunsley@sydney.edu.au
This method is a way to track respiratory motion allowing accurate targeting of tissues during cardiac radioablation. Method for tracking respiratory motion (pdf, 98.8KB)
Inventors: Nicholas Hindley, Suzanne Lydiard, Paul Keall, Chun-Chien Shieh
Contact: emma-louise.hunsley@sydney.edu.au
This invention is a new image reconstruction method for new generation linear accelerators that use rapid CBCT acquisition protocols. Reduction of motion artefacts for 4DCBCT (pdf, 95.3KB)
Inventors: Dr Mark Gardner, Dr Owen Thomas Dillon, Professor Paul Keall, Dr Hilary Byrne
Contact: emma-louise.hunsley@sydney.edu.au
This invention is a new copper-sensing molecular probe with applications for early diagnosis of Parkinson’s disease and management of amyotrophic lateral sclerosis. A biomedical device for precision imaging of copper levels in the CNS (pdf, 78.9KB)
Inventors: Professor Elizabeth New, Professor Kay Double, Marcus Graziotto, Dr Liam Adair
Contact: julius.juarez@sydney.edu.au
This invention is an antivenom treatment offering a broad-spectrum solution for neutralising toxins from various sources including snakes and marine life. A new broad acting antidote for venom-induced local dermal necrosis (pdf, 20.9KB)
Inventors: Professor Graham Neely, Felicity Shu Yin Chung, Nicholas Casewell, Tian Du
Contact: julius.juarez@sydney.edu.au
This invention is a protein-based bioglue formulated to bind to neuronal tissues. Bio glue for high-precision repair of neuronal tissue (pdf, 29.2KB)
Inventors: Dr Jingjing You, Jiawen Fan, Professor Matthew Simunovic, Professor Gerard Sutton, Dr Sheng Hua
Contact: julius.juarez@sydney.edu.au
A series of new ligands that exhibit significantly higher affinity for a biomarker of neuroinflammation. High accuracy agents for imaging neuroinflammation (pdf, 81.1KB)
Inventors: Dr Jonathan Danon, Professor Michael Kassiou, Greta Sohler, Dr Renee Sokias, Dr Tristan Reekie, Dr Eryn Werry
Contact: julius.juarez@sydney.edu.au
This invention relates to new phage-drug nanoconjugates for combating bacterial infections. Innovative phage-drug nanoconjugates to combat antimicrobial resistance (pdf, 47.1KB)
Inventors: Professor Jonathan Iredell, Dr Hien Thi Duong, Huiping Huang
Contact: julius.juarez@sydney.edu.au
A novel phage extracellular vesicle (EV) conjugate designed to promote tissue repair in individuals with bacterial infections. Novel bioactive nano-constructs for treatment of chronic wound infections (pdf, 21.4KB)
Inventors: Professor Wojciech Chrzanowski, Dr Hien Thi Duong
Contact: julius.juarez@sydney.edu.au
This invention relates to peptide mimetic compounds, inspired by the natural healing capabilities of PDGF but engineered to circumvent the pitfalls of prolonged exposure that can lead to fibrosis. Novel peptide mimetic for heart repair (pdf, 30.2KB)
Inventors: A/Professor James Chong, Emily McKinna, Professor Richard James Payne, Daniel Ford, Richard Harvey, Dr Osvaldo Contreras
Contact: julius.juarez@sydney.edu.au
A novel system designed to harness the power of directed evolution within mammalian cells. Novel system for directed evolution in mammalian cells (pdf, 73.1KB)
Inventors: Dr Daniel Hesselson, Professor Graham Gregory Neely, Dr Alexander Cole, Christopher Denes
Contact: julius.juarez@sydney.edu.au
This is a targeted TNBC therapy formed of an antineoplastic agent and an LHRH (Leuteinising hormone release hormone) peptide derivative which has been conjugated to an anti-mitotic agent. Receptor targeted therapy for triple negative breast cancer (pdf, 112.4KB)
Inventors: Dr Pegah Varamini and Sepideh Khazeni.
Contact: julius.juarez@sydney.edu.au
The innovation at hand is a nanoparticle bioconjugate that employs a dual-nanoparticle approach to target and bind to both cancer cells and immune cells. Targeted cancer therapy using bispecific nanoconjugates (pdf, 73.4KB)
Inventors: A/Professor Veysel Kayser, Mariam Tarkistani.
Contact: julius.juarez@sydney.edu.au
A non-toxic, effective new class of iron chelators to treat iron overload disease by removing iron from both plasma and inside cells, surpassing the limitations of existing therapies. New iron chelators for secondary iron overload disease (pdf, 96KB)
Inventors: Rachel Codd, Todd Markham
Contact: taylor.syme@sydney.edu.au
Treating diabetic ulcer and other chronic wounds using an existing class of pharmaceuticals. Chronic wound healing using β3AR agonists (pdf, 142.6KB)
Inventors: Gemma Alexandra Figtree, Kristen Bubb, Belinda Di Bartolo
Contact: taylor.syme@sydney.edu.au
During chemotherapy this sensor monitors platinum complex levels for a more effective adjustment of dosages, and patient treatment plans with few side-effects. Fluorescent sensor for detection of multiple anticancer complexes (pdf, 135KB)
Inventors: Elizabeth New, Linda Mitchell, and Clara Shen.
Contact: julius.juarez@sydney.edu.au
A rapid and specific means of early diagnostics for neurodegenerative diseases such as Alzheimer’s, and acute neurological injuries, such as stroke. Neurological injury & neurodegenerative disease diagnostic (pdf, 82.4KB)
Inventor: Zac Chatterton
Contact: taylor.syme@sydney.edu.au
A vascular bioreactor that presents a more accurate simulation of biological conditions critical for research and development in cardiovascular regenerative medicine. Novel pumping system for close mimicry of human vascular biology (pdf, 55KB)
Inventors: Timothy Mitchell, Steven Wise, Miguel Santos
Contact: emma.louise-hunsley@sydney.edu.au
A targeted TNBC (Triple Negative Breast Cancer) therapy with increased selectivity and efficacy and decreased toxicity. Receptor targeted delivery for antineoplastic agents to breast cancer cells (pdf, 152KB)
Inventors: Pegah Varamini and Sepideh Khazeni
Contact: julius.juarez@sydney.edu.au
A non-invasive device that measures multiple medical signs continuously which can be applied to blood pressure monitors, pulse oximeters, activity & fitness trackers, sleep oxygen monitors, heartrate monitors. Self-training continuous blood pressure monitor (pdf, 71.3KB)
Inventors: Simon Poon and Anusha Withana
Contact: julius.juarez@sydney.edu.au
Physical sciences
Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices health care and soft robotics. Stretchable optical fibre (pdf, 156.4KB)
Inventors: Prof Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, and Dr Md Rejvi Kaysir
Contact: jeremy.cohen@sydney.edu.au
A significant advance in recycling with opportunities in areas including recycled composites for automotive, aerospace, sporting equipment, mining and defence parts, construction materials, 3D printing filaments, and consumer products. Closed-loop recycling of fibre-reinforced plastic composites (pdf, 167.9KB)
Inventor: Dr Ali Hadigheh
Contact: lulu.xue@sydney.edu.au
A technology that adds low cost and simple architecture to the existing advantages of photonics-based radar. Low-frequency photonics-based broadband radar imaging and sensing (36KB)
Inventors: Dr Yang Liu, Mr Ziqian Zhang, Professor Benjamin Eggleton.
Contact: jeremy.cohen@sydney.edu.au
Customising the shells, the nanoparticles’ magnetic properties can be tailored to suit specific applications biomedicine, electronics, and sustainable and renewable energy. Multi-shell magnetic nanoparticles (pdf, 190KB)
Inventors: Prof. Hala Zreiqat AM & Dr Gurvinder Singh
Contact: lulu.xue@sydney.edu.au
A compact wearable ECG monitoring device employing AI-based deep learning algorithms for accurate, real-time diagnosis of cardiac arrhythmia. Wearable ECG monitoring system (pdf, 70.6KB)
Inventors: Prof. Branka Vucetic, A/Prof. Zihuai Lin, and Xucun Yan
Contact: lulu.xue@sydney.edu.au
An improved protein coating process that enables covalent attachment of any protein to a glass surface without using chemical linkers or any additional reagents which could drive a growth in the global medica coatings market. Transparent plasma-activated coated glass substrates (pdf, 139.6KB)
Inventors: Prof. Marcela Bilek, Dr. Clara Thao Hoang Tran, Dr. Stuart Tallis Fraser, Dr. Badwi Bob Boumelhem, and Dr. Aaron Gilmour
Contact: lulu.xue@sydney.edu.au
An on-chip real-time versatile sensing system that can be applied to many in-situ and off-line measurement scenarios including electric vehicle battery monitoring, blood tests and nanoparticles sensing. Microwave photonic multiparameter sensing (pdf, 104.1KB)
Inventors: Prof. Xiaoke Yi, Dr Xiaoyi Tian
Contact: lulu.xue@sydney.edu.au
A revolutionary technology to help those grappling with complex communication needs. Wearable augmentative and alternative communication (wAAC) (pdf, 76.2KB)
Inventors: Prof. Alistair McEwan, Prof. Petra Karlsson, Haifeng Zha
Contact: lulu.xue@sydney.edu.au
Other
A framework designed to support emergency nurses in assessing and managing emergency department patients after triage. HIRAID training materials (149.9KB)
Inventors: Belinda Kennedy, Julie Considine, Kate Curtis, John Mackenzie, Margaret Murphy, Sarah Kourouche, Margaret Fry, Ramon Shaban
Contact: taylor.syme@sydney.edu.au
A custom-designed web-based platform for automating the administration of the Indigenous Tutorial Assistance Scheme-Tertiary Tuition (ITAS-TT) ITAS platform (pdf, 104.3KB)
Creators: Designed at the University of Sydney by the Office of the DVC (Indigenous Strategy and Services) and developed by TechLab in Information and Communication Technology (ICT)
Contact: taylor.syme@sydney.edu.au
Success stories
We're affiliated with a number of startups and new venture projects that have spun out from our technologies.
Kinoxis Therapeutics Pty Ltd was spun out of the University of Sydney in 2018 and has since raised more than $10M to develop its novel anti-addiction drugs for use in the treatment of substance use disorders and other central nervous system disorders.
The spin off follows years of research led by Professor Iain McGregor, which was the first to show oxytocin administration to laboratory animals causes long-term increases in sociability and a lasting decrease in alcohol and methamphetamine self-administration.
Elastagen Pty Ltd is a clinical-stage medical device company that is pioneering Elastatherapy, which uses the human protein elastin to naturally repair and augment the skin.
The company has arisen out of patented research conducted by Professor Tony Weiss’s group and the first clinical trials have demonstrated the biocompatibility and safety of their synthetic human elastin in human subjects.
Elastagen was aquired by leading global biopharmaceutical company, Allergan, in 2018.