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Bring groundbreaking research to market.

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We turn pioneering research into real-world impact. Our diverse portfolio of innovations is ready for licensing, collaboration, and investment—spanning diagnostics, therapeutics, biomedical devices, optical technologies and more.

Summary	A novel biomarker panel capable of determining the risk of PDAC in individuals with high specificity and sensitivity. Project details (pdf, 150KB)
Inventors	Sumit Sahni, Bharat Venkatesh Gundappa, Anubhav Mittal, Jaswinder Samra
Contact	taylor.syme@sydney.edu.au

Summary	Novel inhibitors that target the two-partner secretion system, potentially blocking the secretion of virulence factors in Gram-negative bacteria, offering a new approach to combat bacterial infections. Project details (pdf, 150KB)
Inventors	Matthew Thomas Doyle, Alfred Hartojo, Peggy Cotter, Richard Johnson
Contact	taylor.syme@sydney.edu.au

Summary	A novel urinary biomarker panel capable of determining the risk of PDAC in individuals with high specificity and sensitivity. Project details (pdf, 150KB)
Inventors	Sumit Sahni, Bharat Venkatesh Gundappa, Anubhav Mittal, Jaswinder Samra
Contact	taylor.syme@sydney.edu.au

Summary	Blood biomarker panel for the early detection of pancreatic cancer.
Inventors	Sumit Sahni, Anubhav Mittal, Jaswinder Samra, Mark Molloy, Bharat Venkatesh Gundappa, Matthew J Mckay, Sooin Byeon
Contact	taylor.syme@sydney.edu.au

Summary	An antibody targeting Myc, with the potential to disrupt this otherwise "undruggable" target in various cancers. Project details (pdf, 200KB)
Contact	taylor.syme@sydney.edu.au

Summary	A molecular diagnostic solution with over 95% specificity, leveraging DNA sequencing to objectively differentiate melanoma from benign naevi, thereby reducing the subjectivity and variability of traditional histopathology. Project details (pdf, 250KB)
Inventors	Richard A. Scolyer, Georgina Long, Ismael A. V. Correa, Andrew Colebatch, James Wilmott
Contact	taylor.syme@sydney.edu.au

Summary	A PSA-activated peptide sequence for prodrugs that enables targeted therapy for prostate cancer. A new approach for precision therapy for prostate cancer. Project details (pdf, 150KB)
Inventors	Trevor Hambley, Elisabeth Tondl
Contact	emma-louise.hunsley@sydney.edu.au

Summary	This invention is a new image reconstruction method for new generation linear accelerators that use rapid CBCT acquisition protocols. Project details (pdf, 100KB)
Inventors	Dr Mark Gardner, Dr Owen Thomas Dillon, Professor Paul Keall, Dr Hilary Byrne
Contact	emma-louise.hunsley@sydney.edu.au

Summary	This invention is a new copper-sensing molecular probe with applications for early diagnosis of Parkinson’s disease and management of amyotrophic lateral sclerosis. Project details (pdf, 100KB)
Inventors	Professor Elizabeth New, Professor Kay Double, Marcus Graziotto, Dr Liam Adair
Contact	julius.juarez@sydney.edu.au

Summary	This invention is an antivenom treatment offering a broad-spectrum solution for neutralising toxins from various sources including snakes and marine life. Project details (pdf, 50KB)
Inventors	Professor Graham Neely, Felicity Shu Yin Chung, Nicholas Casewell, Tian Du
Contact	julius.juarez@sydney.edu.au

Summary	This invention is a protein-based bioglue formulated to bind to neuronal tissues. Project details (pdf, 50KB)
Inventors	Dr Jingjing You, Jiawen Fan, Professor Matthew Simunovic, Professor Gerard Sutton, Dr Sheng Hua
Contact	julius.juarez@sydney.edu.au

Summary	A series of new ligands that exhibit significantly higher affinity for a biomarker of neuroinflammation. Project details (pdf, 100KB)
Inventors	Dr Jonathan Danon, Professor Michael Kassiou, Greta Sohler, Dr Renee Sokias, Dr Tristan Reekie, Dr Eryn Werry
Contact	julius.juarez@sydney.edu.au

Summary	This invention relates to new phage-drug nanoconjugates for combating bacterial infections. Project details (pdf, 50KB)
Inventors	Professor Jonathan Iredell, Dr Hien Thi Duong, Huiping Huang
Contact	julius.juarez@sydney.edu.au

Summary	A novel phage extracellular vesicle (EV) conjugate designed to promote tissue repair in individuals with bacterial infections. Project details (pdf, 50KB)
Inventors	Professor Wojciech Chrzanowski, Dr Hien Thi Duong
Contact	julius.juarez@sydney.edu.au

Summary	This invention relates to peptide mimetic compounds, inspired by the natural healing capabilities of PDGF but engineered to circumvent the pitfalls of prolonged exposure that can lead to fibrosis. Project details (pdf, 50KB)
Inventors	A/Professor James Chong, Emily McKinna, Professor Richard James Payne, Daniel Ford, Richard Harvey, Dr Osvaldo Contreras
Contact	julius.juarez@sydney.edu.au

Summary	A novel system designed to harness the power of directed evolution within mammalian cells. Project details (pdf, 100KB)
Inventors	Dr Daniel Hesselson, Professor Graham Gregory Neely, Dr Alexander Cole, Christopher Denes
Contact	julius.juarez@sydney.edu.au

Summary	This is a targeted TNBC therapy formed of an antineoplastic agent and an LHRH (Leuteinising hormone release hormone) peptide derivative which has been conjugated to an anti-mitotic agent. Project details (pdf, 150KB)
Inventors	Dr Pegah Varamini, Sepideh Khazeni
Contact	julius.juarez@sydney.edu.au

Summary	The innovation at hand is a nanoparticle bioconjugate that employs a dual-nanoparticle approach to target and bind to both cancer cells and immune cells. Project details (pdf, 100KB)
Inventors	A/Professor Veysel Kayser, Mariam Tarkistani
Contact	julius.juarez@sydney.edu.au

Summary	During chemotherapy this sensor monitors platinum complex levels for a more effective adjustment of dosages, and patient treatment plans with few side-effects. Project details (pdf, 150KB)
Inventors	Elizabeth New, Linda Mitchell, Clara Shen
Contact	julius.juarez@sydney.edu.au

Summary	A targeted TNBC (Triple Negative Breast Cancer) therapy with increased selectivity and efficacy and decreased toxicity. Project details (pdf, 200KB)
Inventors	Pegah Varamini, Sepideh Khazeni
Contact	julius.juarez@sydney.edu.au

Summary	A non-invasive device that measures multiple medical signs continuously which can be applied to blood pressure monitors, pulse oximeters, activity & fitness trackers, sleep oxygen monitors, and heart rate monitors. Project details (pdf, 100KB)
Inventors	Simon Poon, Anusha Withana
Contact	julius.juarez@sydney.edu.au

Summary	A board game to educate future clinicians about how different members of rural communities interact with the Australian healthcare system. Project details (pdf, 350KB)
Inventors	Heather Russell, Christopher Harrison, Lisa Hampshire, Marguerite Tracy, Annette Burgess, Matthew Tyne, Jayne Crew, Alice Henschke, Catherine Hawke
Contact	emma-louise.hunsley@sydney.edu.au

Summary	A number of novel transcription factors associated with functional CAR-T cell phenotypes and proliferation, and methods of identifying more. Project details (pdf, 150KB)
Inventors	Salvatore Fiorenza, Cameron Turtle
Contact	emma-louise.hunsley@sydney.edu.au

Summary	A novel software capable of tracking the movement of multiple targets during radiation therapy. Project details (pdf, 150KB)
Inventors	Emily Hewson, Paul Keall, Owen Thomas Dillon, Jeremy Booth
Contact	emma-louise.hunsley@sydney.edu.au

Summary	A novel software capable of predicting 3D lung motion with only 10 x-ray projections, for large scale lung disease screening. Project details (pdf, 150KB)
Inventors	Paul Keall, Hunor Kertesz, Owen Dillon, Hilary Byrne, Ricky O'Brien
Contact	emma-louise.hunsley@sydney.edu.au

Summary	A novel software to increase CT image quality thereby improving accuracy and decreasing patient radiation dose. Project details (pdf, 150KB)
Inventors	Natasha Morton, Ricky Thomas O'Brien, Paul Keall, Jeffrey Barber, Jonathan Sykes, John Kipritidis
Contact	emma-louise.hunsley@sydney.edu.au

Summary	Multispectral analysis of urinary biomarkers to non-invasively identify acute tubular necrosis, graft rejection, and non-rejection associated interstitial fibrosis and tubular atrophy. Project details (pdf, 150KB)
Inventors	Sonia Saad, Caroll Pollock, Ewa Goldys, Hon Lin Henry Wu, Yandong Lang
Contact	emma-louise.hunsley@sydney.edu.au

Summary	A small device designed to mimic the appearance of hair, capable of interfacing with the brain for sensing, actuation, and as a delivery mechanism. Project details (pdf, 150KB)
Inventors	Omid Kavehei
Contact	emma-louise.hunsley@sydney.edu.au

Summary	Plasma treatment to enable cell growth within a microfluidic device for greater accuracy. Project details (pdf, 150KB)
Inventors	Marcela Bilek, Jasneil Singh, Anna Waterhouse, Deepu Ashok, Shouyuan Jiang
Contact	emma-louise.hunsley@sydney.edu.au

Summary	Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices, healthcare, and soft robotics. Project details (pdf, 200KB)
Inventors	Professor Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, Dr Md Rejvi Kaysir
Contact	jeremy.cohen@sydney.edu.au

Summary	A significant advance in recycling with opportunities in areas including recycled composites for automotive, aerospace, sporting equipment, mining and defence parts, construction materials, 3D printing filaments, and consumer products. Project details (pdf, 200KB)
Inventors	Dr Ali Hadigheh
Contact	lulu.xue@sydney.edu.au

Summary	A technology that adds low cost and simple architecture to the existing advantages of photonics-based radar. Project details (pdf, 50KB)
Inventors	Dr Yang Liu, Mr Ziqian Zhang, Professor Benjamin Eggleton
Contact	jeremy.cohen@sydney.edu.au

Summary	Customising the shells, the nanoparticles’ magnetic properties can be tailored to suit specific applications in biomedicine, electronics, and sustainable and renewable energy. Project details (pdf, 200KB)
Inventors	Professor Hala Zreiqat AM, Dr Gurvinder Singh
Contact	lulu.xue@sydney.edu.au

Summary	A compact wearable ECG monitoring device employing AI-based deep learning algorithms for accurate, real-time diagnosis of cardiac arrhythmia. Project details (pdf, 100KB)
Inventors	Professor Branka Vucetic, Associate Professor Zihuai Lin, Xucun Yan
Contact	lulu.xue@sydney.edu.au

Summary	An improved protein coating process that enables covalent attachment of any protein to a glass surface without using chemical linkers or any additional reagents, which could drive growth in the global medical coatings market. Project details (pdf, 150KB)
Inventors	Professor Marcela Bilek, Dr Clara Thao Hoang Tran, Dr Stuart Tallis Fraser, Dr Badwi Bob Boumelhem, Dr Aaron Gilmour
Contact	lulu.xue@sydney.edu.au

Summary	An on-chip real-time versatile sensing system that can be applied to many in-situ and off-line measurement scenarios including electric vehicle battery monitoring, blood tests, and nanoparticles sensing. Project details (pdf, 150KB)
Inventors	Professor Xiaoke Yi, Dr Xiaoyi Tian
Contact	lulu.xue@sydney.edu.au

Summary	A revolutionary technology to help those grappling with complex communication needs. Project details (pdf, 100KB)
Inventors	Professor Alistair McEwan, Professor Petra Karlsson, Haifeng Zha
Contact	lulu.xue@sydney.edu.au

Summary	A framework designed to support emergency nurses in assessing and managing emergency department patients after triage. Project details (pdf, 150KB)
Inventors	Belinda Kennedy, Julie Considine, Kate Curtis, John Mackenzie, Margaret Murphy, Sarah Kourouche, Margaret Fry, Ramon Shaban
Contact	taylor.syme@sydney.edu.au

Summary	A custom-designed web-based platform for automating the administration of the Indigenous Tutorial Assistance Scheme-Tertiary Tuition (ITAS-TT). Project details (pdf, 150KB)
Creators	Designed at the University of Sydney by the Office of the DVC (Indigenous Strategy and Services) and developed by TechLab in Information and Communication Technology (ICT)
Contact	taylor.syme@sydney.edu.au

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