Thesis abstract:

«p»«p»Clinical wound therapy is of the utmost importance due to the complex and diverse characteristics of the wound healing process. However, this continues to be a substantial clinical barrier in the development of a wound dressing that can facilitate immediate and remote monitoring, as well as accelerate therapeutic wound healing. Herein, a wound dressing device composed of a thermosensitive hydrogel embedded into high absorption and flexible gold-based conductive foam was developed to accelerate and monitor wound healing processes through the use of interactive dressings, including foams, composites, films, and gels, which facilitate water transmission, re-epithelialization, and granulation. In addition, bioactive substances contained in modified hydrogel were responsively controlled for better wound dressings. By integrating a wireless transmission module into a conductive hydrogel foam dressing, it was possible to wirelessly and instantly monitor the temperature of the wound and control the release of bioactive molecules, which greatly facilitated the timely identification of any infections and improved wound healing acceleration. This study demonstrates significant promise in further exploration of innovative approaches to significantly improve wound management and other therapeutic or diagnostic modalities for pathological conditions.«/p»