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Infrastructure_

Facilities

Enabling research through state-of-the-art infrastructure

We believe pursuing research excellence requires the latest innovative technology across all disciplines. This is why we're investing in major new facilities to grow our broad collection of core research facilities.

The University of Sydney’s core research facilities provide access to high-end research infrastructure and offer a range of related services to assist researchers with specialist applications. These centralised, shared facilities span faculties and serve as focal points of research activity.

Our core research facilities bring together a critical mass of researchers from diverse disciplines, and provide the means to better manage and sustain high-end research infrastructure to conduct quality research.

Our core research facilities

The Research and Prototype Foundry, based at the Sydney Nanoscience Hub, offers state-of-the-art facilities for fabrication of devices and structures with features on the micro and nanoscale, with specialised tools and processes to allow researchers and industry to make nanodevices and prototype new ideas.

Precision on these scales is possible because the tools are housed in a purpose-built cleanroom that provides an environment with extremely precise regulation of temperature, humidity, light and air composition, vibrations, and electromagnetic interference.

Sydney Cytometry provides access to and training in cytometry and cell sorting techniques for researchers, scientists and clinicians from the University community, government research institutes and the health and medical industry. 

The facility was established in 2006 as a collaborative research facility for the Centenary Institute and the University of Sydney. The collaboration has resulted in the acquisition of several sophisticated instruments, which were either world firsts or firsts for Australasia-Oceania and the Southern Hemisphere. The latest acquisition is Australia’s first CyTOF mass cytometer. 

Sydney Cytometry is committed to the development and transfer of cytometry expertise and techniques to answer questions in cell biology and biomedical research, applied clinical research and trials, and the clinical diagnosis of cancer and other health disorders.

Services

  • Access to and training in cytometry instrumentation including analysers and cell sorters
  • Consultation services (experimental design, data acquisition, data analysis and interpretation)
  • Development of cytometry techniques and instrumentation

Key technology

Flow cytometry analysers

A range of instruments from 3 laser/10 parameter flow cytometers, through to Australia’s only 10-laser, 30 parameter high-dimensional flow cytometer.

Image cytometers

Pathway Bioimager (plate-based imaging) and AMNIS ImageStream X (imaging flow cytometer).

Mass cytometers

Helios Mass Cytometer and Australia’s first Hyperion Imaging Mass Cytometer that enables massively multiplex tissue imaging.

Cell sorters

  • FACS Aria IIu (3 laser) cell sorters
  • BD Influx 7 and 10 laser custom cell sorters
  • BD Influx 3 laser cell sorter (within PC3 Facility)

Access

The facility charges user fees, depending on the type of user and the level of support and training required.

New users must register via PPMS and complete biosafety documentation. A user meeting will be arranged to discuss the project and agree upon the research collaboration and appropriate training. Experiments can begin as soon as biosafety approval has been granted.

Contact

Professor Nick King
Core Research Facility Director
T: +61 2 9351 4553
E: nick.king@sydney.edu.au 

Dr Adrian Smith
Technical Director
T: +61 2 8627 1828
E: a.smith@centenary.org.au

Location

Sydney Cytometry has two locations:

  • Level 1, Centenary Institute, Building 93 RPA Hospital on Missenden Road.
  • Level 5, the Hub, Charles Perkins Centre, on the Camperdown Campus.

Sydney Imaging brings together researchers and clinicians, through the provision of exceptional infrastructure and technical expertise, to tackle frontier questions in biomedical research.

With specialist branches dedicated to preclinical and clinical research, Sydney Imaging is structured to provide crucial support for our local, national and global research partners to achieve their most ambitious research objectives. Together with our flagship Hybrid Theatre, built to accommodate robotic surgery and image-guided surgical technologies, Sydney Imaging is a user focussed research facility committed to enabling fundamental and translational research outcomes.

‘Big Data’ and high performance computing have a growing impact in research, both in established fields, such as medicine, geophysics and astronomy, as well as informatics-emergent fields, such as the social sciences and arts. Supporting this change in the nature of research, the Sydney Informatics Hub provides software and services to researchers across the University, including the provision of world-class computational and storage infrastructure, software tools, and data analytics and visualisation services to enable a broad range of approaches to informatics. 

As informatics grows at the University of Sydney, the Informatics Hub will implement a range of high-level solutions to support researchers, including the provision of Virtual Research Desktops to provide direct access to co-located compute and storage resources with analysis and visualisation tools. 

Key technology

Artemis High Performance Computing (HPC)

Artemis is the University of Sydney’s first centrally managed high performance computing (HPC) cluster. Artemis can be accessed over ssh from any location and is provided at no cost to University of Sydney researchers. The computational capacity of high performance computing infrastructure provided by the University of Sydney will continue to grow to meet expanding demand, and will be configured to efficiently and fairly support a range of research project scales.

CLC Genomics

CLC Genomics Workbench is a comprehensive suite of bioinformatics tools packaged into a user-friendly graphical environment. The Workbench is also backed by a dedicated server and late 2016 will be connected with the Artemis HPC. CLC is offered at a heavily discounted rate subsidised by the University and can be booked using Sydney Informatics Hub PPMS. Please email our bioinformatics technician at cali.willet@sydney.edu.au for more information on CLC Genomics Workbench or to request a free trial.

Ingenuity Variant Analysis

Ingenuity Variant Analysis is a web-based application that helps researchers studying human disease to identify causal variants from human sequencing data. The interface is highly intuitive and requires no bioinformatics skills to apply a broad set of analytical tools and features including deep pathway information available in the Ingenuity Knowledge Base. IVA is offered at a discounted rate and can be booked using Sydney Informatics Hub PPMS. Please email our Bioinformatics Technician at cali.willet@sydney.edu.au for more information on IVA.

Services

Research Computing Training

Hands-on training workshops in various informatics topics are provided at no cost to University of Sydney researchers.

Bioinformatics support

Researchers can access advice and support from our bioinformatics technician.

Data Science support

The Sydney Informatics Hub has a team of research engineers focussing on data analytics and visualisation. The team specialises in using statistical and machine learning techniques to provide deeper understanding and insight about a given dataset.

For access to our services, please complete and submit this assistance form.

Contact

Professor Geraint Lewis, Deputy Academic Director
geraint.lewis@sydney.edu.au

Dr Cali Willet, Bioinformatics Technician
cali.willet@sydney.edu.au

Jared Berghold, Lead Engineer
jared.berghold@sydney.edu.au

Location: Available across all campuses.

Services provided by Sydney Mass Spectrometry include a 'research hotel', and training and contract research services to domestic and international researchers.

The facility is housed in purpose-built laboratories in the new Charles Perkins Centre hub building in Camperdown, Sydney.

Find out more about Sydney Mass Spectrometry.

Sydney Microscopy & Microanalysis is a cross-disciplinary research centre which explores physical and biological structures at the micro, nano and atomic scales.

The facility is one of the largest and most comprehensive of its kind in the world, and our instrumentation and technical expertise is available for all researchers.

Find out more about Sydney Microscopy & Microanalysis.

The Vibrational Spectroscopy core research facility houses the largest concentration of state-of-the-art Raman and FT-IR spectrometers in Australia. The instrumentation is available not only to the university community but also to government, not-for-profit organisations, industry and private companies.

Find out more about Vibrational Spectroscopy.

National Collaborative Research Infrastructure Strategy

The National Collaborative Research Infrastructure Strategy (NCRIS) is a federal government initiative that provides funding for major research facilities, supporting infrastructure and networks to drive research excellence. NCRIS builds collaborations between researchers, government and industry to deliver practical outcomes to complex issues challenging our society.

The University of Sydney is involved in the following NCRIS facilities: