People_
Professor Stephen Clarke
OAM
Professor of Medicine
Medicine, Northern Clinical School
Kolling Institute of Medical Research
Medicine, Northern Clinical School
Kolling Institute of Medical Research
Cancer pharmacology, colorectal cancer, lung cancer
Cancer
(Renji Hospital and Shanghai Jiaotong University) Clinical trial of ethnic differences in tolerability of chemotherapy |
Publications
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Book Chapters
- Diakos, C., Charles (nee Slaviero), K., Chua, W., Howell, V., Clarke, S. (2015). Biomarkers in Metastatic Colorectal Cancer. In Victor R. Preedy and Vinood B. Patel (Eds.), Biomarkers in Cancer, (pp. 601-629). Dordrecht: Springer. [More Information]
- McLachlan, A., Clarke, S. (2015). Phytotherapies: Drug Interactions in Cancer. In Not known (Eds.), Phytotherapies: Efficacy, Safety, and Regulation, (pp. 536-553). TBC. [More Information]
- Clarke, S., McLachlan, A. (2012). Interaction Between Complementary and Alternative Medicines and Conventional Medicines. In Olver, I and Robotin, M (Eds.), Perspectives on Complementary and Alternative Medicines, (pp. 227-259). London: Imperial College Press. [More Information]
- Van Der Wall, H., Elison, B., Frater, C., Bruce, W., Clarke, S. (2012). Pathophysiology of Bone Metastases. In Not known (Eds.), Radionuclide and Hybrid Bone Imaging, (pp. 59-84). TBC. [More Information]
- Fung, D., Lo, A., Jankova, L., Clarke, S., Molloy, M., Robertson, G., Wilkins, M. (2011). Classification of Cancer Patients Using Pathway Analysis and Network Clustering. In Gerard Cagney, Andrew Emili (Eds.), Network Biology: Methods and Applications, (pp. 311-336). New York: Humana Press.
- Clarke, S. (2011). Successes, challenges and future directions. In Dimitrios H Roukos (Eds.), Advances in Personalized Cancer Management, (pp. 84-95). London: Future Medicine Ltd. [More Information]
- Clarke, S., McLachlan, A., Brown, D., Carbonara, S., Kissane, R. (2010). Beyond Conventional Cancer Treatments: The Use of Complementary Therapies During Cancer Treatment: Implications for Clinicians. In Monica Robotin, Ian Olver, Afaf Girgis (Eds.), When Cancer Crosses Disciplines: A Physicians Handbook, (pp. 285-315). London: Imperial College Press. [More Information]
- Read, J., Clarke, S. (2008). Clinical Nutrition. In E. Bruera, I. Higginson, C. Ripamonti, C. von Gunten (Eds.), Palliative Medicine, (pp. 595-601). United Kingdom: Hodder Arnold. [More Information]
- Van Der Wall, H., Clarke, S., Murray, I. (2003). Evaluation of primary bone tumours. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 623-639). Edinburgh: Churchill Livingstone.
- Van Der Wall, H., Clarke, S., Murray, I. (2003). The evaluation of malignancy: metastatic bone disease. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 641-655). Edinburgh: Churchill Livingstone.
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Journals
- Tan, L., Brown, C., Mersiades, T., Lee, C., John, T., Kao, S., Newnham, G., O'Byrne, K., Parakh, S., Bray, V., Yip, S., Clarke, S., Pavlakis, N., Stockler, M., et al (2024). A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nature Communications, 15(1). [More Information]
- Thomsen, M., Vemuri, R., Huygens, F., Clarke, S., Vitetta, L. (2024). An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid. Inflammopharmacology. [More Information]
- Brown, L., Khou, V., Brown, C., Alexander, M., Jayamanne, D., Wei, J., Gray, L., Chan, W., Smith, S., Harden, S., Mersiades, T., Itchins, M., Pavlakis, N., Clarke, S., Boyer, M., Nagrial, A., Hau, E., Esteves Domingues Pires da Silva, I., Kao, S., Kong, B., et al (2024). First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study. Frontiers in Oncology, 14. [More Information]
- De Silva, M., Tse, B., Diakos, C., Clarke, S., Molloy, M. (2024). Immunogenic cell death in colorectal cancer: a review of mechanisms and clinical utility. Cancer Immunology, Immunotherapy, 73(3), 53. [More Information]
- De Silva, M., Pavlakis, N., Schembri, G., Chan, D., Bernard, E., Conner, A., Mascall, S., Bailey, D., Roach, P., Clarke, S., Diakos, C. (2024). Metabolic Tumor Volume on 18-Fluorodeoxyglucose Positron Emission Tomography as a Prognostic Marker of Survival in Patients with Locally Advanced or Metastatic Neuroendocrine Neoplasms Treated with 177Lutetium-DOTA-Octreotate Peptide Receptor Radionuclide Therapy. Pancreas, 53(7), e560-e565. [More Information]
- Wei, J., Yuile, A., Itchins, M., Kong, B., Li, B., Pavlakis, N., Chan, D., Clarke, S. (2023). Anti-PD-1 Monoclonal Antibodies (mAbs) Are Superior to Anti-PD-L1 mAbs When Combined with Chemotherapy in First-Line Treatment for Metastatic Non-Small Cell Lung Cancer (mNSCLC): A Network Meta-Analysis. Biomedicines, 11(7). [More Information]
- Saltz, L., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2023). Bevacizumab in Combination with Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study. Journal of Clinical Oncology, 41(21), 3663-3669. [More Information]
- Tse, B., Molloy, M., Bergamin, S., Steffen, P., Hruby, G., Pavlakis, N., Clarke, S., Evans, J., Engel, A., Kneebone, A. (2023). CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy. OncoImmunology, 12(1), 2238506. [More Information]
- Bendell, J., LoRusso, P., Overman, M., Noonan, A., Kim, D., Strickler, J., Kim, S., Clarke, S., George, T., Grimison, P., et al (2023). First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors. Cancer Immunology, Immunotherapy, 72(7), 2443-2458. [More Information]
- Mckay, M., Castaneda, M., Catania, S., Charles (nee Slaviero), K., Shanahan, E., Clarke, S., Engel, A., Varelis, P., Molloy, M. (2023). Quantification of short-chain fatty acids in human stool samples by LC-MS/MS following derivatization with aniline analogues. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1217. [More Information]
- Gordon, S., Chan, D., Bernard, E., Eslick, M., Willowson, K., Roach, P., Engel, A., Maher, R., Clarke, S., Agarwal, V., De Silva, M., Conner, A., Pavlakis, N., Bailey, D., et al (2023). Single-centre experience with peptide receptor radionuclide therapy for neuroendocrine tumours (NETs): results using a theranostic molecular imaging-guided approach. Journal of Cancer Research and Clinical Oncology. [More Information]
- Ahmadzada, T., Vijayan, A., Vafaee, F., Azimi, A., Reid, G., Clarke, S., Kao, S., Grau, G., Hosseini Beheshti, E. (2023). Small and Large Extracellular Vesicles Derived from Pleural Mesothelioma Cell Lines Offer Biomarker Potential. Cancers, 15(8). [More Information]
- Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]
- Itchins, M., Ainsworth, H., Alexander, M., Dean, S., Dharmaraj, D., Pavlakis, N., Clarke, S., Brown, C., Torres, J., Saqib, A., Kao, S., et al (2022). A Multi-Center Real-World Experience of IMpower150 in Oncogene Driven Tumors and CNS Metastases. Clinical Lung Cancer, 23(8), 702-708. [More Information]
- Siu, D., Ali, A., Tjokrowidjaja, A., De Silva, M., Lee, J., Clingan, P., Aghmesheh, M., Brungs, D., Mapagu, C., Goldstein, D., Sjoquist, K., Pavlakis, N., Clarke, S., Diakos, C., et al (2022). Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers. Asia-Pacific Journal of Clinical Oncology, 18(6), 660-668. [More Information]
- Chan, D., Clarke, S., Engel, A., Diakos, C., Pavlakis, N., Roach, P., Bailey, D., Bauer, J., Findlay, M. (2022). Computed tomography (CT)-defined sarcopenia and myosteatosis are prevalent in patients with neuroendocrine neoplasms (NENs) treated with peptide receptor radionuclide therapy (PRRT). European Journal of Clinical Nutrition, 76(1), 143-149. [More Information]
- Bhimani, N., Wong, G., Molloy, C., Pavlakis, N., Diakos, C., Clarke, S., Dieng, M., Hugh, T. (2022). Cost of treating metastatic colorectal cancer: a systematic review. Public Health, 211, 97-104. [More Information]
- Lovell, M., Phillips, J., Luckett, T., Lam, L., Boyle, F., Davidson, P., Cheah, S., McCaffrey, N., Currow, D., Shaw, T., Clarke, S., Lee, J., Clark, K., et al (2022). Effect of Cancer Pain Guideline Implementation on Pain Outcomes Among Adult Outpatients With Cancer-Related Pain: A Stepped Wedge Cluster Randomized Trial. JAMA Network Open, 5(2), e220060-1-e220060-12. [More Information]
- Whittle, K., Kao, S., Clarke, S., Grau, G., Hosseini Beheshti, E. (2022). Exploring the role of extracellular vesicles and their protein cargo in lung cancer metastasis: A review. Critical Reviews in Oncology / Hematology (online), 171, 103603-1-103603-11. [More Information]
- Khin, N., De Silva, M., Clarke, S., Pavlakis, N., Rogan, C., Ho-Shon, K., Lane, R. (2022). Liver Isolation Oxaliplatin (LIOX): Long Term Survival from a New Locoregional Technique for Chemorefractory Patients with Colorectal Liver Metastases. Annals of Surgical Oncology, 29(6), 3387-3389. [More Information]
- Batty, K., Taylor, A., Bernard, E., Diakos, C., Clarke, S., Guminski, A., Baron-Hay, S., Boyle, F., Pavlakis, N., Chan, D. (2022). Metastatic primary breast neuroendocrine neoplasms: a case series. Internal Medicine Journal. [More Information]
- Maharaj, A., Lubel, J., Lam, E., Clark, P., Duncan, O., George, J., Jeffrey, G., Lipton, L., Liu, H., McCaughan, G., Tu, T., et al (2022). Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus. Hepatology Communications, 6(11), 3260-3271. [More Information]
- Clarke, S., Butcher, B., McLachlan, A., Henson, J., Rutolo, D., Hall, S., Vitetta, L. (2022). Pilot clinical and pharmacokinetic study of Δ⁹-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain. PloS One, 17(10 October). [More Information]
- Nahm, C., Turchini, J., Sahni, S., Millar, E., Itchins, M., Arena, J., Cho, A., Colvin, E., Howell, V., Pavlakis, N., Clarke, S., Samra, J., Gill, A., Mittal, A. (2022). The Right Treatment Strategy for the Right Patient: A Biomarker-Driven Approach to Neoadjuvant vs. Surgery-First Management of Resectable and Borderline Resectable Pancreatic Cancer. Cancers, 14(15). [More Information]
- Jambor, M., Ashrafizadeh, A., Nahm, C., Clarke, S., Pavlakis, N., Kneebone, A., Hruby, G., Gill, A., Mittal, A., Samra, J. (2022). The role of staging laparoscopy in pancreatic adenocarcinoma and its effect on patients’ survival. World Journal of Surgical Oncology, 20(1). [More Information]
- Lubel, J., Roberts, S., Strasser, S., Thompson, A., Philip, J., Goodwin, M., Clarke, S., Crawford, D., Levy, M., Shackel, N. (2021). Australian recommendations for the management of hepatocellular carcinoma: a consensus statement. Medical Journal of Australia, 214(10), 475-483. [More Information]
- Mondaca, S., Lebow, E., Namakydoust, A., Razavi, P., Reis-Filho, J., Shen, R., Offin, M., Tu, H., Murciano-Goroff, Y., Xu, C., Pavlakis, N., Clarke, S., Itchins, M., Lee, A., et al (2021). Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions. Lung Cancer, 159, 66-73. [More Information]
- Leal, J., Alexander, M., Itchins, M., Wright, G., Kao, S., Hughes, B., Pavlakis, N., Clarke, S., Gill, A., Ainsworth, H., et al (2021). EGFR Exon 20 Insertion Mutations: Clinicopathological Characteristics and Treatment Outcomes in Advanced Non–Small Cell Lung Cancer: EGFR Exon 20 Insertion Mutations in NSCLC. Clinical Lung Cancer, 22(6), e859-e869. [More Information]
- Davis, A., Kao, S., Clarke, S., Boyer, M., Pavlakis, N. (2021). Emerging biological therapies for the treatment of malignant pleural mesothelioma. Expert Opinion on Emerging Drugs, 26(2), 179-192. [More Information]
- Oh, B., Boyle, F., Pavlakis, N., Clarke, S., Guminski, A., Eade, T., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Hruby, G., Stevens, M., Molloy, M., Back, M., et al (2021). Emerging Evidence of the Gut Microbiome in Chemotherapy: A Clinical Review. Frontiers in Oncology, 11, 706331. [More Information]
- Gordon, E., Chan, D., Arena, J., Bernard, E., Carr-Boyd, E., Clarke, S., Itchins, M., Learoyd, D., Sandanayake, N., Pavlakis, N. (2021). Life-threatening diarrhea in neuroendocrine tumors: two case reports. Journal of Medical Case Reports, 15(1), 542. [More Information]
- Davis, A., Clarke, S., Ayesa, S., Chan, D. (2021). Marked improvement in hyperammonaemic encephalopathy from multimodal treatment of metastatic neuroendocrine tumour. BMJ Case Reports, 14(6), e241191-1-e241191-4. [More Information]
- Maloney, S., Itchins, M., Arena, J., Sahni, S., Howell, V., Hayes, S., Gill, A., Clarke, S., Samra, J., Mittal, A., Pavlakis, N. (2021). Optimal Upfront Treatment in Surgically Resectable Pancreatic Cancer Candidates: A High-Volume Center Retrospective Analysis. Journal of Clinical Medicine, 10(12), 2700. [More Information]
- Ding, P., Roberts, T., Chua, W., Becker, T., Caixeiro, N., de Souza, P., Gao, B., Lee, C., Itchins, M., Westman, H., Clarke, S., Bray, V., et al (2021). Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib. Translational Lung Cancer Research, 10(4), 1623-1634. [More Information]
- Liu, J., Itchins, M., Nagrial, A., Cooper, W., De Silva, M., Barnet, M., Varikatt, W., Sivasubramaniam, V., Davis, A., Gill, A., Blinman, P., Lee, K., Hui, R., Pavlakis, N., Clarke, S., Boyer, M., Kao, S., et al (2021). Relationship between PD-L1 expression and outcome in EGFR-mutant lung cancer patients treated with EGFR tyrosine kinase inhibitors. Lung Cancer, 155, 28-33. [More Information]
- Illini, O., Hochmair, M., Fabikan, H., Weinlinger, C., Tufman, A., Swalduz, A., Lamberg, K., Hashemi, S., Huemer, F., Vikström, A., et al (2021). Selpercatinib in RET fusion-positive non-small-cell lung cancer (SIREN): a retrospective analysis of patients treated through an access program. Therapeutic Advances in Medical Oncology, 13. [More Information]
- Wijetunga, A., Chua, T., Nahm, C., Pavlakis, N., Clarke, S., Chan, D., Diakos, C., Maloney, S., Ashrafi-Zadeh, A., Kneebone, A., Gill, A., Mittal, A., Samra, J., et al (2021). Survival in borderline resectable and locally advanced pancreatic cancer is determined by the duration and response of neoadjuvant therapy: Survival in advanced pancreatic cancer. European Journal of Surgical Oncology, 47(10), 2543-2550. [More Information]
- Oh, B., Boyle, F., Pavlakis, N., Clarke, S., Eade, T., Hruby, G., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Stevens, M., Molloy, M., Kong, B., Back, M., et al (2021). The gut microbiome and cancer immunotherapy: Can we use the gut microbiome as a predictive biomarker for clinical response in cancer immunotherapy? Cancers, 13(19), 4824. [More Information]
- Oh, B., Eade, T., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Hruby, G., Stevens, M., Boyle, F., Clarke, S., Molloy, M., Back, M., et al (2021). The gut microbiome and gastrointestinal toxicities in pelvic radiation therapy: A clinical review. Cancers, 13(10), 2353. [More Information]
- Bhimani, N., Brown, K., Kelly, P., Molloy, C., Xue, A., Clarke, S., Rasmussen, H., Hugh, T. (2021). The prognostic significance of tumour FXYD-3 expression in patients with primary and secondary colorectal cancers. Frontiers in Gastroenterology & Hepatology, 1(1), 1-10. [More Information]
- Alexander, M., Pavlakis, N., John, T., O'Connell, R., Kao, S., Hughes, B., Lee, A., Hayes, S., Howell, V., Clarke, S., Itchins, M., et al (2020). A multicenter study of thromboembolic events among patients diagnosed with ROS1-rearranged non-small cell lung cancer. Lung Cancer, 142, 34-40. [More Information]
- Itchins, M., Lau, B., Hudson, A., Westman, H., Xia, C., Hayes, S., Howell, V., Rodriguez, M., Cooper, W., Wei, G., Buckland, M., Li, B., Gill, A., Clarke, S., Pavlakis, N., et al (2020). ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 25(8), 641-649. [More Information]
- Sagnella, S., Yang, L., Stubbs, G., Boslem, E., Martino-Echarri, E., Smolarczyk, K., Pattison, S., Vanegas, N., St. Clair, E., Clarke, S., et al (2020). Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells. Cancer Cell, 37(3), 354-3.70. [More Information]
- Smith-Uffen, M., Johnson, S., Martin, A., Tattersall, M., Stockler, M., Bell, M., Detering, K., Clayton, J., Silvester, W., Clarke, S., Vaccaro, L., Beale, P., Kiely, B. (2020). Estimating survival in advanced cancer: a comparison of estimates made by oncologists and patients. Supportive Care in Cancer, 28(7), 3399-3407. [More Information]
- Itchins, M., Chua, T., Arena, J., Jamieson, N., Nahm, C., O'Connell, R., Bailey, E., Schembri, G., Gill, A., Kneebone, A., Hruby, G., Mittal, A., Pavlakis, N., Clarke, S., Samra, J. (2020). Evaluation of Fluorodeoxyglucose Positron Emission Tomography Scanning in the Neoadjuvant Therapy Paradigm in Pancreatic Ductal Adenocarcinoma. Pancreas, 49(2), 224-229. [More Information]
- Ahmadzada, T., Kao, S., Reid, G., Clarke, S., Grau, G., Hosseini Beheshti, E. (2020). Extracellular vesicles as biomarkers in malignant pleural mesothelioma: A review. Critical Reviews in Oncology / Hematology (online), 150, 102949. [More Information]
- Chan, D., Bernard, E., Schembri, G., Roach, P., Johnson, M., Pavlakis, N., Clarke, S., Bailey, D. (2020). High Metabolic Tumour Volume on 18-Fluorodeoxyglucose Positron Emission Tomography Predicts Poor Survival from Neuroendocrine Neoplasms. Neuroendocrinology, 110(11-12), 950-958. [More Information]
- Sahni, S., Nahm, C., Krisp, C., Molloy, M., Mehta, S., Maloney, S., Itchins, M., Pavlakis, N., Clarke, S., Chan, D., Gill, A., Howell, V., Samra, J., Mittal, A. (2020). Identification of Novel Biomarkers in Pancreatic Tumor Tissue to Predict Response to Neoadjuvant Chemotherapy. Frontiers in Oncology, 10, 1-10. [More Information]
- Harris, B., Phan, V., Perera, V., Szyc, A., Galettis, P., Martin, J., Walpole, E., McLachlan, A., Clarke, S., Reuter, S., Charles (nee Slaviero), K. (2020). Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes. Clinical Pharmacokinetics, 59(8), 1013-1026. [More Information]
- Lyu, N., Rajendran, V., Diefenbach, R., Charles (nee Slaviero), K., Clarke, S., Engel, A., Rizos, H., Molloy, M., Wang, Y. (2020). Multiplex detection of ctdna mutations in plasma of colorectal cancer patients by pcr/sers assay. Nanotheranostics, 4(4), 224-232. [More Information]
- Karsten, E., Breen, E., McCracken, S., Clarke, S., Herbert, B. (2020). Red blood cells exposed to cancer cells in culture have altered cytokine profiles and immune function. Scientific Reports, 10(1), 7727. [More Information]
- Ahmadzada, T., Cooper, W., Holmes, M., Mahar, A., Westman, H., Gill, A., Nordman, I., Yip, P., Pal, A., Zielinski, R., Pavlakis, N., Nagrial, A., Daneshvar, D., Karikios, D., Grau, G., Hosseini Beheshti, E., Clarke, S., Kao, S., et al (2020). Retrospective evaluation of the use of pembrolizumab in malignant mesothelioma in a real-world Australian population. JTO Clinical and Research Reports, 1(4), 1-15. [More Information]
- Ackland, S., Michael, M., de Souza, P., Martin, J., Clarke, S., Francis, K., Karapetis, C., Gurney, H. (2020). Science and art of anticancer drug dosing: nine steps to personalised therapy. Internal Medicine Journal, 50(8), 992-996. [More Information]
- Chan, J., Diakos, C., Engel, A., Chan, D., Pavlakis, N., Gill, A., Clarke, S. (2020). Serum bicarbonate is a marker of perioperative mortality but is not associated with long term survival in colorectal cancer. PloS One, 15(1), 1-14. [More Information]
- McKelvey, K., Hudson, A., Kumar, R., Eade, T., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Sub-acute Toxicity in Non-cancerous Tissue and Immune-Related Adverse Events of a Novel Combination Therapy for Cancer. Frontiers in Oncology, 9, 1504. [More Information]
- McKelvey, K., Hudson, A., Kumar, R., Wilmott, J., Attrill, G., Long, G., Scolyer, R., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model. PloS One, 15(4), e0226444. [More Information]
- Jang, A., Brown, C., Lamoury, G., Morgia, M., Boyle, F., Marr, I., Clarke, S., Back, M., Oh, B. (2020). The Effects of Acupuncture on Cancer-Related Fatigue: Updated Systematic Review and Meta-Analysis. Integrative Cancer Therapies, 19. [More Information]
- Oh, B., Bae, K., Lamoury, G., Eade, T., Boyle, F., Corless, B., Clarke, S., Yeung, A., Rosenthal, D., Schapira, L., Back, M. (2020). The Effects of Tai Chi and Qigong on Immune Responses: A Systematic Review and Meta-Analysis. Medicines, 7(7), 39. [More Information]
- Tjokrowidjaja, A., Goldstein, D., Hudson, M., Lord, S., Gebski, V., Clarke, S., de Souza, P., Motzer, R., Lee, C. (2020). The impact of neutrophil-lymphocyte ratio on risk reclassification of patients with advanced renal cell cancer to guide risk-directed therapy. Acta Oncologica, 59(1), 20-27. [More Information]
- Clarke, S., Burge, M., Feeney, K., Gibbs, P., Jones, K., Marx, G., Molloy, M., Price, T., Reece, W., Segelov, E., et al (2020). The prognostic role of inflammatory markers in patients with metastatic colorectal cancer treated with bevacizumab: A translational study [ASCENT]. PloS One, 15(3), e0229900. [More Information]
- Sabari, J., Offin, M., Stephens, D., Ni, A., Lee, A., Pavlakis, N., Clarke, S., Diakos, C., Datta, S., Tandon, N., et al (2019). A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers. Journal of the National Cancer Institute, 111(6), 1-9. [More Information]
- Lai, W., Lebas, L., Barnes, T., Milia, J., Gautschi, O., Ni, A., Peters, S., Ferrara, R., Plodkowski, A., Kavanagh, J., Clarke, S., Pavlakis, N., et al (2019). Afatinib in patients with metastatic or recurrent HER2-mutant lung cancers: a retrospective international multicentre study. European Journal of Cancer, 109, 28-35. [More Information]
- Trousil, S., Lee, P., Edwards, R., Maslen, L., Lozan‐Kuehne, J., Ramaswami, R., Aboagye, E., Clarke, S., Liddle, C., Sharma, R. (2019). Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation. British Journal of Pharmacology, 176(18), 3712-3722. [More Information]
- Nahm, C., Turchini, J., Jamieson, N., Moon, E., Sioson, L., Itchins, M., Arena, J., Colvin, E., Howell, V., Pavlakis, N., Clarke, S., Samra, J., Gill, A., Mittal, A. (2019). Biomarker panel predicts survival after resection in pancreatic ductal adenocarcinoma: A multi-institutional cohort study. European Journal of Surgical Oncology, 45(2), 218-224. [More Information]
- Ahmadzada, T., Lee, K., Clarke, C., Cooper, W., Linton, A., McCaughan, B., Asher, R., Clarke, S., Reid, G., Kao, S. (2019). High BIN1 expression has a favorable prognosis in malignant pleural mesothelioma and is associated with tumor infiltrating lymphocytes. Lung Cancer, 130, 35-41. [More Information]
- Back, M., Jayamanne, D., Brazier, D., Newey, A., Bailey, D., Schembri, G., Hsiao, E., Khasraw, M., Wong, M., Kastelan, M., Clarke, S., Wheeler, H., et al (2019). Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management. Journal of Medical Imaging and Radiation Oncology, 63(2), 272-280. [More Information]
- Shinko, D., McGuire, H., Diakos, C., Pavlakis, N., Clarke, S., Byrne, S., Charles (nee Slaviero), K. (2019). Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients. Frontiers in Immunology, 10, 1-12. [More Information]
- Currey, N., Jahan, Z., Caldon, E., Tran, P., Benthani, F., De Lacavalerie, P., Roden, D., Gloss, B., Campos, C., Bean, E., Clarke, S., et al (2019). Mouse Model of 'Mutated in Colorectal Cancer' Gene Deletion Reveals Novel Pathways in Inflammation and Cancer. Cellular and Molecular Gastroenterology and Hepatology, 7(4), 819-839. [More Information]
- Janssen, Q., Buettner, S., Suker, M., Beumer, B., Addeo, P., Bachellier, P., Bahary, N., Bekaii-Saab, T., Bali, M., Besselink, M., Clarke, S., Samra, J., et al (2019). Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis. Journal of the National Cancer Institute, 111(8), 782-794. [More Information]
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- Learoyd, D., Clarke, S. (2019). Straddling medical specialties: should we have more comprehensive advanced training? Internal Medicine Journal, 49(5), 669-671. [More Information]
- Vitetta, L., Chen, J., Clarke, S. (2019). The vermiform appendix: an immunological organ sustaining a microbiome inoculum. Clinical Science, 133(1), 1-8. [More Information]
- Kwok, G., Zhao, J., Glover, A., Ip, J., Sywak, M., Clifton-Bligh, R., Clarke, S., Robinson, B., Sidhu, S. (2019). Treatment and management of adrenal cancer in a specialized Australian endocrine surgical unit: approaches, outcomes and lessons learnt. ANZ Journal of Surgery, 89(1-2), 48-52. [More Information]
- Chan, J., Diakos, C., Engel, A., Chan, D., Pavlakis, N., Gill, A., Clarke, S. (2019). Tumor sidedness is not an independent prognostic marker of colorectal cancer patients undergoing curative resection: A retrospective cohort study. PloS One, 14(6), 1-15. [More Information]
- Vafaee, F., Diakos, C., Kirschner, M., Reid, G., Michael, M., Horvath, L., Alinejad-Rokny, H., Cheng, Z., Kuncic, Z., Clarke, S. (2018). A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis. Npj Systems Biology And Applications, 4, 20. [More Information]
- Chan, J., Diakos, C., Chan, D., Engel, A., Pavlakis, N., Gill, A., Clarke, S. (2018). A Longitudinal Investigation of Inflammatory Markers in Colorectal Cancer Patients Perioperatively Demonstrates Benefit in Serial Remeasurement. Annals of Surgery, 267(6), 1119-1125. [More Information]
- Johnson, S., Butow, P., Bell, M., Detering, K., Clayton, J., Silvester, W., Kiely, B., Clarke, S., Vaccaro, L., Stockler, M., Tattersall, M., et al (2018). A randomised controlled trial of an advance care planning intervention for patients with incurable cancer. British Journal of Cancer, 119(10), 1182-1190. [More Information]
- Oh, B., Yeung, A., Klein, P., Larkey, L., Ee, C., Zaslawski, C., Knobf, M., Payne, P., Stener-Victorin, E., Lee, R., Pavlakis, N., Boyle, F., Clarke, S., Back, M., et al (2018). Accreditation Standard Guideline Initiative for Tai Chi and Qigong Instructors and Training Institutions. Medicines, 5(2), 51. [More Information]
- Oh, B., Eade, T., Kneebone, A., Hruby, G., Lamoury, G., Pavlakis, N., Clarke, S., Zaslawski, C., Marr, I., Costa, D., Back, M. (2018). Acupuncture in Oncology: The Effectiveness of Acupuncture May Not Depend on Needle Retention Duration. Integrative Cancer Therapies, 17(2), 458-466. [More Information]
- Li, B., Shen, R., Buonocore, D., Olah, Z., Ni, A., Ginsberg, M., Ulaner, G., Offin, M., Feldman, D., Hembrough, T., Pavlakis, N., Clarke, S., et al (2018). Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial. Journal of Clinical Oncology, 36(24), 2532-2537. [More Information]
- Lane, R., Khin, N., Pavlakis, N., Hugh, T., Clarke, S., Magnussen, J., Rogan, C., Flekser, R. (2018). Challenges in chemotherapy delivery: comparison of standard chemotherapy delivery to locoregional vascular mass fluid transfer. Future Oncology, 14(7), 647-663. [More Information]
- Wong, E., Jacques, S., Bennett, M., Gorolay, V., Lee, A., Clarke, S. (2018). Complete response in a patient with stage IV adrenocortical carcinoma treated with adjuvant trans-catheter arterial chemo-embolization (TACE). Asia-Pacific Journal of Clinical Oncology, 14(3), 279-281. [More Information]
- Itchins, M., Clarke, S., Pavlakis, N. (2018). Do EGFR tyrosine kinase inhibitors (TKIs) still have a role in EGFR wild-type pre-treated advanced non-small cell lung cancer (NSCLC)?-the shifting paradigm of therapeutics. Translational Lung Cancer Research, 7(Suppl 1), S39-S45. [More Information]
- Yu, S., Arima, H., Bertmar, C., Clarke, S., Herkes, G., Krause, M. (2018). Neutrophil to lymphocyte ratio and early clinical outcomes in patients with acute ischemic stroke. Journal of the Neurological Sciences, 387, 115-118. [More Information]
- Leyden, J., Pavlakis, N., Chan, D., Michael, M., Clarke, S., Khasraw, M., Price, T. (2018). Patient-reported experience of the impact and burden of neuroendocrine tumors:Oceania patient results from a large global survey. Asia-Pacific Journal of Clinical Oncology, 14(3), 256-263. [More Information]
- Itchins, M., Hayes, S., Gill, A., Cooper, W., O'Connell, R., Howell, V., Clarke, S., Pavlakis, N. (2018). Pattern of care and survival of anaplastic lymphoma kinase rearranged non-small cell lung cancer (ALK+ NSCLC) in an Australian Metropolitan Tertiary Referral Centre: A retrospective cohort analysis. Asia-Pacific Journal of Clinical Oncology, 14(5), e275-e282. [More Information]
- Itchins, M., Arena, J., Pavlakis, N., Nahm, C., Gibbs, E., Mohamudally, A., Maher, R., Bailey, D., Schembri, G., Gill, A., Diakos, C., Khasraw, M., Hruby, G., Kneebone, A., Mittal, A., Samra, J., Clarke, S., et al (2018). Pattern of care and survival of pancreatic ductal adenocarcinoma in a multi-disciplinary high-volume centre. Gastroenterology & Hepatology, 9(5), 185-189. [More Information]
- Sjoquist, K., Renfro, L., Simes, R., Tebbutt, N., Clarke, S., Seymour, M., Adams, R., Maughan, T., Saltz, L., Goldberg, R., et al (2018). Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 110(6), 638-648. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Renton, C., Clarke, S., Tannock, I. (2018). Prognostic indices of inflammatory markers, cognitive function and fatigue for survival in patients with localised colorectal cancer. ESMO Open, 3, e000302. [More Information]
- Chou, A., Froio, D., Nagrial, A., Parkin, A., Murphy, K., Chin, V., Wohl, D., Steinmann, A., Stark, R., Drury, A., Clarke, S., Gill, A., et al (2018). Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer. Gut, 67(12), 2142-2155. [More Information]
- Lane, R., Khin, N., Rogan, C., Magnussen, J., Ho-Shon, K., Pavlakis, N., Clarke, S., Hugh, T. (2018). The integration of pharmacology and pathophysiology into locoregional chemotherapy delivery via mass fluid transfer. Journal of Controlled Release, 292, 18-28. [More Information]
- Thomsen, M., Clarke, S., Vitetta, L. (2018). The role of adjuvant probiotics to attenuate intestinal inflammatory responses due to cancer treatments. Beneficial Microbes, 9(6), 899-916. [More Information]
- Hayes, S., Clarke, S., Pavlakis, N., Howell, V. (2018). The role of proteomics in the age of immunotherapies. Mammalian Genome, 29, 757-769. [More Information]
- John, T., Bowden, J., Clarke, S., Fox, S., Garrett, K., Horwood, K., Karapetis, C. (2017). Australian recommendations for EGFR T790M testing in advanced non-small cell lung cancer. Asia-Pacific Journal of Clinical Oncology, 13(4), 296-303. [More Information]
- Shinko, D., Diakos, C., Clarke, S., Charles (nee Slaviero), K. (2017). Cancer-Related Systemic Inflammation: The Challenges and Therapeutic Opportunities for Personalized Medicine. Clinical Pharmacology & Therapeutics, 102(4), 599-610. [More Information]
- Willowson, K., Bernard, E., Maher, R., Clarke, S., Bailey, D. (2017). Changing Therapeutic Paradigms: Predicting mCRC Lesion Response to Selective Internal Radionuclide Therapy (SIRT) based on Critical Absorbed Dose Thresholds: A Case Study. Asia Oceania Journal of Nuclear Medicine & Biology, 5(1), 66-69. [More Information]
- Willowson, K., Hayes, A., Chan, D., Tapner, M., Bernard, E., Maher, R., Pavlakis, N., Clarke, S., Bailey, D. (2017). Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis. EJNMMI Research, 7(1), 1-13. [More Information]
- Chan, D., Pavlakis, N., Schembri, G., Bernard, E., Hsiao, E., Hayes, A., Barnes, T., Diakos, C., Khasraw, M., Samra, J., Eslick, E., Roach, P., Engel, A., Clarke, S., Bailey, D. (2017). Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: proposal for a Novel Grading Scheme with Prognostic Significance. Theranostics, 7(5), 1149-1158. [More Information]
- Oh, B., Eade, T., Kneebone, A., Pavlakis, N., Clarke, S., Eslick, G., River, J., Back, M. (2017). Factors affecting whether or not cancer patients consider using acupuncture. Acupuncture in Medicine, 35(2), 107-113. [More Information]
- Dhillon, H., Bell, M., van der Ploeg, H., Turner, J., Kabourakis, M., Spencer, L., Lewis, C., Hui, R., Blinman, P., Clarke, S., Boyer, M., Vardy, J. (2017). Impact of physical activity on fatigue and quality of life in people with advanced lung cancer: A randomized controlled trial. Annals of Oncology, 28(8), 1889-1897. [More Information]
- Tio, M., Tsui, P., Fischer, G., Clarke, S. (2017). Osimertinib induced bullous dermatitis. Cancer Treatment and Research Communications, 13, 25-26. [More Information]
- Kim, S., Itchins, M., Arena, J., Nahm, C., Pavlakis, N., Clarke, S., Gill, A., Samra, J., Mittal, A. (2017). Patterns and Determinants of Recurrence for Pancreatic Ductal Adenocarcinoma after Resection. Journal of the Pancreas, 18(6), 458-464.
- Chan, D., Clarke, S., Diakos, C., Roach, P., Bailey, D., Singh, S., Pavlakis, N. (2017). Prognostic and predictive biomarkers in neuroendocrine tumours. Critical Reviews in Oncology/Hematology, 113, 268-282. [More Information]
- Itchins, M., Arena, J., Nahm, C., Rabindran, J., Kim, S., Gibbs, E., Bergamin, S., Chua, T., Gill, A., Maher, R., Diakos, C., Mittal, A., Hruby, G., Kneebone, A., Pavlakis, N., Samra, J., Clarke, S., et al (2017). Retrospective cohort analysis of neoadjuvant treatment and survival in resectable and borderline resectable pancreatic ductal adenocarcinoma in a high volume referral centre. European Journal of Surgical Oncology, 43(9), 1711-1717. [More Information]
- van Zandwijk, N., Pavlakis, N., Kao, S., Linton, A., Boyer, M., Clarke, S., Huynh, Y., Chrzanowska, A., Fulham, M., Bailey, D., Cooper, W., Kritharides, L., Reid, G., et al (2017). Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study. The Lancet Oncology, 18(10), 1386-1396. [More Information]
- Selinger, C., Li, B., Pavlakis, N., Links, M., Gill, A., Lee, A., Clarke, S., Tran, T., Lum, T., Yip, P., Horvath, L., Yu, B., O'Toole, S., Cooper, W., et al (2017). Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target. Histopathology, 70(3), 402-411. [More Information]
- Lee, A., Chan, D., Wong, M., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2017). Systematic Review of the Role of Targeted Therapy in Metastatic Neuroendocrine Tumors. Neuroendocrinology, 104(3), 209-222. [More Information]
- Chan, J., Chan, D., Diakos, C., Engel, A., Pavlakis, N., Gill, A., Clarke, S. (2017). The Lymphocyte-to-Monocyte Ratio is a Superior Predictor of Overall Survival in Comparison to Established Biomarkers of Resectable Colorectal Cancer. Annals of Surgery, 265(3), 539-546. [More Information]
- Itchins, M., Chia, P., Hayes, S., Howell, V., Gill, A., Cooper, W., John, T., Mitchell, P., Millward, M., Clarke, S., Pavlakis, N., et al (2017). Treatment of ALK-rearranged non-small cell lung cancer: A review of the landscape and approach to emerging patterns of treatment resistance in the Australian context. Asia-Pacific Journal of Clinical Oncology, 13, 3-13. [More Information]
- Kao, S., Kirschner, M., Cooper, W., Tran, T., Burgers, S., Wright, C., Korse, T., van den Broek, D., Edelman, J., Vallely, M., McCaughan, B., Pavlakis, N., Clarke, S., van Zandwijk, N., Reid, G., et al (2016). A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma. British Journal of Cancer, 114(5), 524-531. [More Information]
- Johnson, S., Clayton, J., Butow, P., Silvester, W., Detering, K., Hall, J., Kiely, B., Cebon, J., Clarke, S., Bell, M., Stockler, M., Tattersall, M., et al (2016). Advance care planning in patients with incurable cancer: Study protocol for a randomised controlled trial. BMJ Open, 6(12), 1-10. [More Information]
- Song, X., Amirkhani, A., Wu, J., Pascovici, D., Zaw, T., Xavier, D., Clarke, S., Molloy, M. (2016). Analytical performance of nano-LC-SRM using nondepleted human plasma over an 18-month period. Proteomics, 16(15-16), 2118-2127. [More Information]
- Reid, G., Kao, S., Pavlakis, N., Brahmbhatt, H., MacDiarmid, J., Clarke, S., Boyer, M., van Zandwijk, N. (2016). Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer. Epigenomics, 8(8), 1079-1085. [More Information]
- Sclafani, F., Kim, T., Cunningham, D., Kim, T., Tabernero, J., Schmoll, H., Roh, J., Kim, S., Park, Y., Guren, T., Clarke, S., et al (2016). Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial. International Journal of Cancer, 140(2), 431-439. [More Information]
- Malalasekera, M., Tan, C., Phan, V., Yip, P., Vardy, J., Clarke, S., Kao, S. (2016). Eastern Cooperative Oncology Group score: Agreement between non-small-cell lung cancer patients and their oncologists and clinical implications. Cancer Treatment Communications, 5, 17-21. [More Information]
- Hayes, S., Haefliger, S., Harris, B., Pavlakis, N., Clarke, S., Molloy, M., Howell, V. (2016). Exhaled breath condensate for lung cancer protein analysis: a review of methods and biomarkers. Journal of Breath Research, 10(3), 1-26. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Renton, C., Dodd, A., Zhang, H., Clarke, S., Tannock, I. (2016). Fatigue in people with localized colorectal cancer who do and do not receive chemotherapy: a longitudinal prospective study. Annals of Oncology, 27(9), 1761-1767. [More Information]
- Oh, B., Figtree, G., Costa, D., Eade, T., Hruby, G., Lim, S., Elfiky, A., Martine, N., Rosenthal, D., Clarke, S., Back, M. (2016). Oxidative stress in prostate cancer patients: A systematic review of case control studies. Prostate International, 4(3), 71-87. [More Information]
- Bailey, D., Lee, A., Li, B., Clarke, S. (2016). PET monitoring of liver directed selective internal radionuclide therapy for metastatic gastro-oesophageal cancer. BMJ Case Reports, 2016, bcr2016215645. [More Information]
- Wong, E., Oh, L., Nahar, K., Lee, A., Clarke, S. (2016). Primary Pericardial Sarcoma with Right Atrial Invasion and Multiple Bilateral Pulmonary Metastases in a Patient with Hereditary Nonpolyposis Colorectal Cancer. Case Reports in Oncological Medicine, 2016. [More Information]
- Lane, R., Khin, N., Rogan, C., Magnussen, J., Pavlakis, N., Lane, D., Clarke, S. (2016). Safety and Feasibility of Repeatable Hepatic Vascular Isolation Chemotherapy: A Pilot Study. Annals of Surgical Oncology, 23(11), 3699-3708. [More Information]
- Dong, S., Costa, D., Butow, P., Lovell, M., Agar, M., Velikova, G., Teckle, P., Jaure, A., Tebbutt, N., Clarke, S., King, M., et al (2016). Symptom Clusters in Advanced Cancer Patients: An Empirical Comparison of Statistical Methods and the Impact on Quality of Life. Journal of Pain and Symptom Management, 51(1), 88-98. [More Information]
- Wong, M., Chan, D., Lee, A., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2016). Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET). PloS One, 11(6), 1-15. [More Information]
- Charles (nee Slaviero), K., Harris, B., Haddad, C., Clarke, S., Guminski, A., Stevens, M., Dodds, T., Gill, A., Back, M., Veivers, D., Eade, T. (2016). Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and nonoropharyngeal patients. BMC Cancer, 16(1), 1-13. [More Information]
- Li, B., Barnes, T., Chan, D., Naidoo, J., Lee, A., Khasraw, M., Marx, G., Kris, M., Clarke, S., Drilon, A., Pavlakis, N., et al (2016). The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials. Lung Cancer, 102, 21-27. [More Information]
- Kao, S., Fulham, M., Wong, K., Cooper, W., Brahmbhatt, H., MacDiarmid, J., Pattison, S., Sagong, J., Huynh, Y., Leslie, F., Pavlakis, N., Clarke, S., Boyer, M., Reid, G., van Zandwijk, N. (2015). A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma. American Journal of Respiratory and Critical Care Medicine, 191(12), 1467-1469. [More Information]
- Furtado, R., Ha, L., Clarke, S., Sandroussi, C. (2015). Adjuvant Iodine (131) Lipiodol after Resection of Hepatocellular Carcinoma. Journal of Oncology, 2015, 1-7. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Rourke, S., Bekele, T., Renton, C., Dodd, A., Zhang, H., Beale, P., Clarke, S., et al (2015). Cognitive Function in Patients With Colorectal Cancer Who Do and Do Not Receive Chemotherapy: A Prospective, Longitudinal, Controlled Study. Journal of Clinical Oncology, 33(34), 4085-4092. [More Information]
- Park, W., Li, B., Maher, R., Samra, J., Clarke, S., Bernard, E., Bailey, D., Pavlakis, N. (2015). Dramatic response to selective internal radiation therapy for unresectable hepatocellular carcinoma. Oxford Medical Case Reports, 2015 (2), 194-195. [More Information]
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- Ip, J., Pang, T., Glover, A., Soon, P., Zhao, J., Clarke, S., Robinson, B., Gill, A., Sidhu, S. (2015). Immunohistochemical validation of overexpressed genes identified by global expression microarrays in adrenocortical carcinoma reveals potential predictive and prognostic biomarkers. The Oncologist, 20(3), 247-256. [More Information]
- Ip, J., Pang, T., Glover, A., Soon, P., Clarke, S., Richardson, A., Campbell, P., Robinson, B., Sidhu, S. (2015). Improving Outcomes in Adrenocortical Cancer: An Australian Perspective. Annals of Surgical Oncology, 22(7), 2309-2316. [More Information]
- Zardawi, S., Li, B., Zauderer, M., Wang, J., Atmore, B., Barnes, T., Pavlakis, N., Mathur, M., Clarke, S. (2015). Localized malignant pleural mesothelioma with renal metastasis. Oxford Medical Case Reports, 2015 (1), 170-172. [More Information]
- Glover, A., Zhao, J., Gill, A., Weiss, J., Mugridge, N., Kim, E., Feeney, A., Ip, J., Reid, G., Clarke, S., Robinson, B., Sidhu, S., et al (2015). microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma. Oncotarget, 6(34), 36675-36688. [More Information]
- Michael, M., White, S., Abdi, E., Nott, L., Clingan, P., Zimet, A., Button, P., Gregory, D., Solomon, B., Dobrovic, A., Clarke, S., et al (2015). Multicenter randomized, open-label phase II trial of sequential erlotinib and gemcitabine compared with gemcitabine monotherapy as first-line therapy in elderly or ECOG PS two patients with advanced NSCLC. Asia-Pacific Journal of Clinical Oncology, 11(1), 4-14. [More Information]
- Haddad, C., Guo, L., Clarke, S., Guminski, A., Back, M., Eade, T. (2015). Neutrophil-to-lymphocyte ratio in head and neck cancer. Journal of Medical Imaging and Radiation Oncology, 59(4), 514-519. [More Information]
- Chan, D., Clarke, S., Gill, A., Chantrill, L., Samra, J., Li, B., Barnes, T., Nahar, K., Pavlakis, N. (2015). Pathogenic PALB2 mutation in metastatic pancreatic adenocarcinoma and neuroendocrine tumour: A case report. Molecular and Clinical Oncology, 3(4), 817-819. [More Information]
- Jankova, L., Dent, O., Molloy, M., Chan, C., Chapuis, P., Howell, V., Clarke, S. (2015). Reporting in studies of protein biomarkers of prognosis in colorectal cancer in relation to the REMARK guidelines. Proteomics - Clinical Applications, 9(11-12), 1078-1086. [More Information]
- Mehta, S., de Reuver, P., Gill, P., Andrici, J., D'Urso, L., Mittal, A., Pavlakis, N., Clarke, S., Samra, J., Gill, A. (2015). Somatostatin Receptor SSTR-2a Expression Is a Stronger Predictor for Survival Than Ki-67 in Pancreatic Neuroendocrine Tumors. Medicine, 94(40), 1-6. [More Information]
- Zhou, J., Belov, L., Chapuis, P., Chan, C., Armstrong, N., Alexander, K., Solomon, M., Clarke, S., Christopherson, R. (2015). Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. Journal of Immunological Methods, 416, 59-68. [More Information]
- Tan, C., Read, J., Phan, V., Beale, P., Peat, J., Clarke, S. (2015). The relationship between nutritional status, inflammatory markers and survival in patients with advanced cancer: a prospective cohort study. Supportive Care in Cancer, 23(2), 385-391. [More Information]
- Wang, F., Gill, A., Neale, M., Puttaswamy, V., Gananadha, S., Pavlakis, N., Clarke, S., Hugh, T., Samra, J. (2014). Adverse tumor biology associated with mesenterico-portal vein resection influences survival in patients with pancreatic ductal adenocarcinoma. Annals of Surgical Oncology, 21(6), 1937-1947. [More Information]
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- Chik, J., Zhou, J., Moh, E., Christopherson, R., Clarke, S., Molloy, M., Packer, N. (2014). Comprehensive glycomics comparison between colon cancer cell cultures and tumours: Implications for biomarker studies. Journal of Proteomics, 108, 146-162. [More Information]
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- Kohonen-Corish, M., Tseung, J., Chan, C., Currey, N., Dent, O., Clarke, S., Bokey, L., Chapuis, P. (2014). KRAS mutations and CDKN2A promoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer. International Journal of Cancer, 134(12), 2820-2828. [More Information]
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- Chua, W., Moore, M., Beale, P., Clarke, S. (2009). Third-line Treatment Options for Metastatic Colorectal Cancer. Asia Pacific Journal of Oncology and Hematology, 1(1), 27-35.
- Van Cutsem, E., Verslype, C., Beale, P., Clarke, S., Bugat, R., Rakhit, A., Fettner, S., Brennscheidt, U., Feyereislova, A., Delord, J. (2008). A phase lb dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients. Annals of Oncology, 19(2), 332-339. [More Information]
- Saltz, L., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2008). Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. Journal of Clinical Oncology, 26(12), 2013-2019. [More Information]
- Sharma, R., Kacevska, M., London, R., Clarke, S., Liddle, C., Robertson, G. (2008). Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies. British Journal of Cancer, 98(1), 91-97. [More Information]
- Robertson, G., Liddle, C., Clarke, S. (2008). Inflammation and Altered Drug Clearance in Cancer: Transcriptional Repression of a Human CYP3A4 Transgene in Tumor-bearing Mice. Pharmacology and Therapeutics, 83(6), 894-897. [More Information]
- Kacevska, M., Robertson, G., Clarke, S., Liddle, C. (2008). Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing. Expert Opinion on Drug Metabolism and Toxicology, 4(2), 137-149. [More Information]
- Oh, B., Butow, P., Mullan, B., Clarke, S. (2008). Medical Qigong for cancer patients: Pilot study of impact on quality of life, side effects of treatment and inflammation. American Journal of Chinese Medicine, 36(3), 459-472. [More Information]
- Harrison, J., Solomon, M., Young, J., Meagher, A., Butow, P., Salkeld, G., Hruby, G., Clarke, S. (2008). Patient and physician preferences for surgical and adjuvant treatment options for rectal cancer. JAMA (formerly Archives Of Surgery), 143(4), 389-394. [More Information]
- Haller, D., Cassidy, J., Clarke, S., Cunningham, D., Hoff, P., Rothenberg, M., Saltz, L., Allegra, C., et al (2008). Potential regional differences for the tolerability profiles of fluoropyrimidines. Journal of Clinical Oncology, 26(13), 2118-2123. [More Information]
- Cassidy, J., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2008). Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. Journal of Clinical Oncology, 26(12), 2006-2012. [More Information]
- Morgan, E., Goralski, K., Piquette-Miller, M., Renton, K., Robertson, G., Chaluvadi, M., Charles, K., Clarke, S., Kacevska, M., Liddle, C., et al (2008). Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer. Drug Metabolism and Disposition, 36(2), 205-216. [More Information]
- Chua, W., Beale, P., Clarke, S., Leung, M. (2008). Retrospective review of mitomycin C use as third-line chemotherapy in metastatic colorectal cancer. Asia-Pacific Journal of Clinical Oncology, 4(3), 132-136. [More Information]
- Zalcberg, J., Rosen, L., Abdi, E., Davis, I., Gutheil, J., Schnell, F., Cesano, A., Gayko, U., Chen, M., Clarke, S. (2008). Role of Palifermin in Fluorouracil-Based Therapy for Metastatic Colorectal Cancer. Journal of Clinical Oncology, 26(8), 1386-1387. [More Information]
- Sharma, R., Zucknick, M., London, R., Kacevska, M., Liddle, C., Clarke, S. (2008). Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer. Clinical Colorectal Cancer, 7(5), 331-337. [More Information]
- Sharma, R., Hoskins, J., Rivory, L., Zucknick, M., London, R., Liddle, C., Clarke, S. (2008). Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients. Clinical Cancer Research, 14(3), 817-825. [More Information]
- Yeo, W., Boyer, M., Chung, H., Ong, S., Lim, R., Zee, B., Ma, B., Lam, K., Mo, F., Ng, E., Clarke, S., Beale, P., et al (2007). Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG). Cancer Chemotherapy and Pharmacology, 59(3), 295-300. [More Information]
- Clarke, S., Goldstein, D., Mitchell, P., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S. (2007). Modification of Leucovorin Dose Within a Simplified FOLFOX Regimen Improves Tolerability Without Compromising Efficacy. Clinical Colorectal Cancer, 6(8), 578-582. [More Information]
- Chuah, B., Lim, R., Boyer, M., Ong, A., Wong, S., Kong, H., Millward, M., Clarke, S., Goh, B. (2007). Multi-centre phase II trial of Thalidomide in the treatment of unresectable hepatocellular carcinoma. Acta Oncologica, 46(2), 234-238. [More Information]
- Li, K., Rivory, L., Clarke, S. (2007). Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules. British Journal of Cancer, 97(8), 1071-1076. [More Information]
- Harrison, J., Solomon, M., Young, J., Meagher, A., Hruby, G., Salkeld, G., Clarke, S. (2007). Surgical and oncology trials for rectal cancer: Who will participate? Surgery, 142(1), 94-101. [More Information]
- McKay, M., Sherman, J., Laver, M., Baker, M., Clarke, S., Molloy, M. (2007). The development of multiple reaction monitoring assays for liver-derived plasma proteins. Proteomics - Clinical Applications, 1(12), 1570-1581. [More Information]
- Leighl, N., Shepherd, H., Butow, P., Clarke, S., McJannett, M., Beale, P., Wilcken, N., Moore, M., Chen, E., Tattersall, M., Goldstein, D. (2007). When the goal is not cure: A randomized trial of a patient decision aid in advanced colorectal cancer. Journal of Clinical Oncology, 25(18S), 6509.
- Sharma, R., Rivory, L., Beale, P., Ong, S., Horvath, L., Clarke, S. (2006). A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer. British Journal of Cancer, 94(7), 964-968. [More Information]
- Tobin, P., Beale, P., Noney, L., Liddell, S., Rivory, L., Clarke, S. (2006). A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer. Cancer Chemotherapy and Pharmacology, 57(3), 309-316. [More Information]
- Mitchell, P., Goldstein, D., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S., Thomson, J., Clarke, S. (2006). Addition of gabapentin to a modified FOLFOX regimen does not reduce oxaliplatin-induced neurotoxicity. Clinical Colorectal Cancer, 6(2), 146-151. [More Information]
- Nordman, I., Iyer, S., Joshua, A., Clarke, S. (2006). Advances in the adjuvant treatment of colorectal cancer. ANZ Journal of Surgery, 76(5), 373-380. [More Information]
- Read, J., Choy, S., Beale, P., Clarke, S. (2006). An evaluation of the prevalence of malnutrition in cancer patients attending the outpatient oncology clinic. Asia-Pacific Journal of Clinical Oncology, 2(2), 80-86. [More Information]
- Clarke, S., Sharma, R. (2006). Angiogenesis inhibitors in cancer - mechanisms of action. Australian Prescriber, 29(1), 9-12.
- Stockler, M., Tattersall, M., Boyer, M., Clarke, S., Beale, P., Simes, R. (2006). Disarming the guarded prognosis: predicting survival in newly referred patients with incurable cancer. British Journal of Cancer, 94(2), 208-212. [More Information]
- Read, J., Choy, S., Beale, P., Clarke, S. (2006). Evaluation of nutritional and inflammatory status of advanced colorectal cancer patients and its correlation with survival. Nutrition and Cancer, 55(1), 78-85. [More Information]
- Read, J., Beale, P., Volker, D., Smith, N., Childs, A., Clarke, S. (2006). Nutrition intervention using an eicosapentaenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: a phase II trial. Supportive Care in Cancer, 15(3), 301-307. [More Information]
- Rosen, L., Abdi, E., Davis, I., Gutheil, J., Schnell, F., Zalcberg, J., Cesano, A., Gayko, U., Chen, M., Clarke, S. (2006). Palifermin Reduces the Incidence of Oral Mucositis in Patients With Metastatic Colorectal Cancer Treated With Fluorouracil-Based Chemotherapy. Journal of Clinical Oncology, 24, 5194-5200. [More Information]
- Aggarwal, G., Glare, P., Clarke, S., Chapuis, P. (2006). Palliative and shared care concepts in patients with advanced colorectal cancer. ANZ Journal of Surgery, 76(3), 175-180. [More Information]
- Charles (nee Slaviero), K., Rivory, L., Stockler, M., Beale, P., Beith, J., Boyer, M., Clarke, S. (2006). Predicting the toxicity of weekly docetaxel in advanced cancer. Clinical Pharmacokinetics, 45(6), 611-622. [More Information]
- Michael, M., Goldstein, D., Clarke, S., Milner, A., Beale, P., Friedlander, M., Mitchell, P. (2006). Prognostic Factors Predictive of Response and Survival to a Modified FOLFOX Regimen: Importance of an Increased Neutrophil Count. Clinical Colorectal Cancer, 6(4), 297-304. [More Information]
- Michael, M., Thompson, M., Hicks, R., Mitchell, P., Ellis, A., Milner, A., Di Iulio, J., Scott, A., Gurtler, V., Clarke, S., Zalcberg, J., et al (2006). Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination. Journal of Clinical Oncology, 24(26), 4228-4235. [More Information]
- Li, K., Rivory, L., Clarke, S. (2006). Solid-phase extraction (SPE) techniques for sample preparation in clinical and pharmaceutical analysis: A brief overview. Current Pharmaceutical Analysis, 2(2), 95-102. [More Information]
- Tobin, P., Clarke, S., Seale, J., Lee, S., Solomon, M., Aulds, S., Crawford, M., Gallagher, J., Eyers, T., Rivory, L. (2006). The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours. British Journal of Clinical Pharmacology, 62(1), 122-129. [More Information]
- Ackland, S., Clarke, S., Beale, P., Peters, G. (2006). Thymidylate synthase inhibitors. Update on Cancer Therapeutics, 1(4), 403-427. [More Information]
- Charles (nee Slaviero), K., Rivory, L., Brown, S., Liddle, C., Clarke, S., Robertson, G. (2006). Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer. Clinical Cancer Research, 12(24), 7492-7497. [More Information]
- Clarke, S., Boyer, M., Millward, M., Underhill, C., Moylan, E., Yip, D., White, S., Childs, A., Beale, P., Latz, J., et al (2005). A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer. Lung Cancer, 49(3), 401-412. [More Information]
- Goldstein, D., Mitchell, P., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S., Clarke, S. (2005). Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients. British Journal of Cancer, 92(5), 832-837. [More Information]
- Sharpe, L., Butow, P., Smith, C., McConnell, D., Clarke, S. (2005). Changes in quality of life in patients with advanced cancer - Evidence of response shift and response restriction. Journal of Psychosomatic Research, 58(6), 497-504. [More Information]
- Vardy, J., Clarke, S. (2005). Ewing''s sarcoma of the rectum: Are four cycles of chemotherapy enough? Reply. Journal of Clinical Oncology, 23(24), 5850-5850.
- Sharma, R., Boyer, M., Clarke, S., Millward, M. (2005). Gefitinib in advanced non-small cell lung cancer. Internal Medicine Journal, 35(2), 77-82. [More Information]
- Joshua, A., Cotroneo, A., Clarke, S. (2005). Humor and oncology. Journal of Clinical Oncology, 23(3), 645-648. [More Information]
- Read, J., Beale, P., Horvath, L., Volker, D., Childs, A., Smith, N., Clarke, S. (2005). Impact of fish-oil supplement on nutritional parameters, inflammation and chemotherapy induced toxicity in colorectal cancer (CRC) patients receiving FOLFIRI - A pilot study. Journal of Clinical Oncology, 23(16S (supplement)), Abstract 8243 S789-S789.
- Sharma, R., Tobin, P., Clarke, S. (2005). Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea. The Lancet Oncology, 6(2), 93-102. [More Information]
- Read, J., Crockett, N., Volker, D., MacLennan, P., Choy, S., Beale, P., Clarke, S. (2005). Nutritional assessment in cancer: comparing the Mini-Nutritional Assessment (MNA) with the scored Patient-Generated Subjective Global Assessment (PGSGA). Nutrition and Cancer, 53(1), 51-56. [More Information]
- Li, K., Rivory, L., Clarke, S. (2005). Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 820(1), 121-130. [More Information]
- Joshua, A., Adams, D., McKenzie, P., Solomon, M., Clarke, S. (2005). Small blue cell tumors of the rectum. Case 2. Small-cell carcinoma of the rectum. Journal of Clinical Oncology, 23(4), 912-3. [More Information]
- Sharma, R., McLeod, D., Clarke, S. (2005). Small blue cell tumors of the rectum. Case 3. Atypical carcinoid of the rectum. Journal of Clinical Oncology, 23(4), 914-5. [More Information]
- Vardy, J., Joshua, A., Clarke, S., Yarrow, P., Lin, B. (2005). Small blue cell tumors of the rectum: CASE 1. Ewing's sarcoma of the rectum. Journal of Clinical Oncology, 23(4), 910-912. [More Information]
- Joshua, A., Boyer, M., Subramanian, R., Clarke, S. (2005). Smoking reduction does work: resulting alterations in the incidence and histological subtypes of lung cancer in New South Wales in the last 20 years. Respirology, 10(2), 233-238. [More Information]
- Sharpe, L., Butow, P., Smith, C., McConnell, D., Clarke, S. (2005). The relationship between available support, unmet needs and caregiver burden in patients with advanced cancer and their carers. Psycho-Oncology, 14(2), 102-114. [More Information]
- Joshua, A., Nordman, I., Venkataswaran, R., Clarke, S., Stockler, M., Boyer, M. (2005). Weekly docetaxel as second line treatment after mitozantrone for androgen-independent prostate cancer. Internal Medicine Journal, 35(8), 468-472. [More Information]
- Baker, S., Van Schaik, R., Rivory, L., Ten Tije, A., Dinh, K., Graveland, W., Schenk, P., Charles, J., Clarke, S., Carducci, M., Sparreboom, A., et al (2004). Factors Affecting Cytochrome P-450 3A Activity In Cancer Patients. Clinical Cancer Research, 10(12), 8341-8350. [More Information]
- Tobin, P., Rivory, L., Clarke, S. (2004). Inhibition of acetylcholinesterase in patients receiving irinotecan (camptothecin-11). Pharmacology and Therapeutics, 76(5), 505-506. [More Information]
- Vardy, J., Engelhardt, K., Cox, K., Jacquet, J., McDade, A., Boyer, M., Beale, P., Clarke, S., Stockler, M., Loneragan, R., Waugh, R., Clarke, S. (2004). Long-Term Outcome Of Radiological-Guided Insertion Of Implanted Central Venous Access Port Devices (Cvapd) For The Delivery Of Chemotherapy In Cancer Patients: Institutional Experience And Review Of The Literature. British Journal of Cancer, 91(6), 1045-1049. [More Information]
- Blair, E., Rivory, L., Clarke, S., McLachlan, A. (2004). Population Pharmacokinetics Of Raltitrexed In Patients With Advanced Solid Tumours. British Journal of Clinical Pharmacology, 57(4), 416-426. [More Information]
- Charles (nee Slaviero), K., Clarke, S., McLachlan, A., Blair, E., Rivory, L. (2004). Population Pharmacokinetics Of Weekly Docetaxel In Patients With Advanced Cancer. British Journal of Clinical Pharmacology, 57(1), 44-53. [More Information]
- Zhang, M., Boyer, M., Rivory, L., Hong, A., Clarke, S., Stevens, G., Fife, K. (2004). Radiosensitization Of Vinorelbine And Gemcitabine In Nci-H460 Non-Small-Cell Lung Cancer Cells. International Journal of Radiation: Oncology - Biology - Physics, 58(2), 353-360. [More Information]
- Featherstone, C., Clarke, S., Jackson, M., Shannon, K., McNeil, E., Tin, M., Clifford, A., O'Brien, C. (2004). Treatment Of Advanced Cancer Of The Larynx And Hypopharynx With Chemoradiation. ANZ Journal of Surgery, 74(7), 554-558. [More Information]
- Smit, E., Mattson, K., von Pawel, J., Manegold, C., Clarke, S., Postmus, P. (2003). ALIMTA® (pemetrexed disodium) as second-line treatment of non-small-cell lung cancer: a phase II study. Annals of Oncology, 14(3), 455-460. [More Information]
- Clarke, S. (2003). An 85-year old woman with metastatic liver disease: clinical case review. Medicine Today, 4(1), 72-73.
- Charles (nee Slaviero), K., Read, J., Clarke, S., Rivory, L. (2003). Baseline Nutritional Assessment in Advanced Cancer Patients Receiving Palliative Chemotherapy. Nutrition and Cancer, 46(2), 148-157. [More Information]
- Tattersall, M., Clarke, S. (2003). Developments in drug delivery: implications for cancer care. Current Opinion in Oncology, 15(4), 293-299. [More Information]
- Charles (nee Slaviero), K., Clarke, S., Rivory, L. (2003). Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy. The Lancet Oncology, 4(4), 224-232. [More Information]
- Saw, R., Morgan, M., Koorey, D., Painter, D., Findlay, M., Stevens, G., Clarke, S., Chapuis, P., Solomon, M. (2003). P53, deleted in colorectal cancer gene, and thymidylate synthase as predictors of histopathologic response and survival in low, locally advanced rectal cancer treated with preoperative adjuvant therapy. Diseases of the Colon and Rectum, 46(2), 192-202. [More Information]
- Li, K., Clarke, S., Rivory, L. (2003). Quantitation of plasma thymidine by high-performance liquid chromatography - atmospheric pressure chemical ionization mass spectromentry and its application to pharmocodynamic studies in cancer patients. Analytica Chimica Acta, 486(1), 51-61. [More Information]
- Tobin, P., Dodds, H., Clarke, S., Schnitzler, M., Rivory, L. (2003). The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours. Oncology Reports, 10(6), 1977-1979.
- Aristides, M., Chen, J., Schulz, M., Williamson, E., Clarke, S., Grant, K. (2002). Conjoint analysis of a new chemotherapy: willingness to pay and preference for the features of raltitrexed versus standard therapy in advanced colorectal cancer. PharmacoEconomics, 20(11), 775-784. [More Information]
- Cunningham, D., Zalcberg, J., Maroun, J., James, R., Clarke, S., Maughan, T., Vincent, M., Schulz, J., Gonzalez Baron, M., Facchini, T. (2002). Efficacy, tolerability and management of raltitrexed (Tomudex TM) monotherapy in patients with advanced colorectal cancer: a review of phase II/III trials. European Journal of Cancer, 38(4), 478-486. [More Information]
- Rivory, L., Charles (nee Slaviero), K., Clarke, S. (2002). Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. British Journal of Cancer, 87(3), 277-280. [More Information]
- Vardy, J., Wong, E., Izard, M., Clifford, A., Clarke, S. (2002). Life-threatening anaphylactoid reaction to amifostine used with concurrent chemoradiotherapy for nasopharyngeal cancer in a patient with dermatomyositis: a case report with literature review. Anti-Cancer Drugs, 13(3), 327-330. [More Information]
- Clarke, S. (2002). New treatments for advanced and metastatic colorectal cancer - clinical applications. Australian Prescriber, 25(5), 111-113. [More Information]
- Rischin, D., Ackland, S., Smith, J., Garg, M., Clarke, S., Millward, M., Toner, G., Zalcberg, J. (2002). Phase I and pharmacokinetic study of docetaxel in combination with epirubicin and cyclophosphamide in advanced cancer: dose escalation possible with granulocyte colony-stimulating factor, but not with prophylactic antibodies. Annals of Oncology, 13(11), 1810-1818. [More Information]
- Clarke, S., Abratt, R., Goedhals, L., Boyer, M., Millward, M., Ackland, S. (2002). Phase II trial of pemetrexed disodium (ALIMTA[R], LY231514) in chemotherapy-naive patients with advanced non-small-cell lung cancer. Annals of Oncology, 13(5), 737-741. [More Information]
- Rivory, L., Clarke, S., Boyer, M., Bishop, J. (2001). Highly sensitive analysis of the antifolate pemetrexed sodium, a new cancer agent, in human plasma and urine by high-performance liquid chromatography. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 765, 135-140.
- Rivory, L., Charles (nee Slaviero), K., Hoskins, J., Clarke, S. (2001). The erythromycin breath test for the prediction of drug clearance. Clinical Pharmacokinetics, 40, 151-158. [More Information]
- Clarke, S., Bishop, J., Dodds, H., Rivory, L., Ong,, S. (2001). Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction. Anti-Cancer Drugs, 12, 619-625. [More Information]
- Clarke, S., Beale, P., Rivory, L. (2000). Clinical and preclinical pharmacokinetics of raltitrexed. Clinical Pharmacokinetics, 39, 429-443. [More Information]
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Conferences
- Johnson, S., Butow, P., Bell, M., Detering, K., Clayton, J., Silvester, W., Kiely, B., Clarke, S., Vaccaro, L., Stockler, M., Beale, P., Fitzgerald, N., Tattersall, M. (2017). A Randomized Controlled Trial of an Advance Care Planning Intervention for Patients with Incurable Cancer. The 44th Clinical Oncological Society of Australia Annual Scientific Meeting,.
- Vaccaro, L., Johnson, S., Kiely, B., Clayton, J., Clarke, S., Beale, P., Silvester, W., Detering, K., Butow, P., Tattersall, M. (2016). Acceptability of tailored life-expectancy information in patients with advanced cancer participating in an Australian nurse-led ACP RCT. The 43nd Clinical Oncological Society of Australia Annual Scientific Meeting,.
- Clarke, S. (2013). A Medical Oncology Approach to Colorectal Cancer. Cancer Nurses Society of Australia Educational Event 2011.
- Clarke, S. (2013). An Australian Translational Study to Evaluate the Prognostic Role of lnflammatorv Markers in Patients with Metastatic Colorectal Cancer Treated with Bevacizumab (Avastin TM ) [ASCENT]. 2012 COSA 39th Annual Scientific Meeting.
- Clarke, S. (2012). Comparison of nutritional assessment with a new definition of cachexia in determining outcomes of advanced cancer patients. European Society of Medical Oncology 2012 Congress.
- Clarke, S. (2012). Lower Gastrointestinal Cancers Update. 2012 Roche Products Adelaide Post-ASCO Education Meeting.
- Clarke, S. (2012). Plasma biomarkers of outcome in CRC. Merck Serono Australia Tailored Therapies Meeting- The New Era- Focus on Colorectal Cancer.
- Clarke, S. (2012). Predictive and prognostics factors associated with Mesothelioma and Lung Cancer. Lilly Oncology Australian Scientific Exchange Meeting 2012.
- Clarke, S. (2012). Prognostic Factors in Colorectal Cancer. Roche Haematology & Oncology Targeted Therapies (HOTT) Symposium 2012.
- Clarke, S. (2012). Translational research at the Kolling Institute of Medical Research. 5th Annual Hunter Cancer Research Symposium.
- Clarke, S. (2012). What are a treating team's obligations to ensure access to treatment and compensation for mesothelioma sufferers? 4th Australian Lung Cancer Conference.
- Clarke, S. (2011). Bone Metastases. Nuclear Medicine Society NSW Educational Meeting.
- Clarke, S. (2011). Cancer in Northern Sydney. Kolling Institute of Medical Research Public Forum "Our Fight Against Cancer".
- Clarke, S. (2011). Plenary address: Cancer Research at the Universitv of Sydney. Cancer Research Network Postgraduate Symposium 2011.
- Clarke, S. (2011). Predicting outcomes in Lung Cancer. The Second Oncology Forum of Chinese Physicians from China and the US (OFCCU).
- Clarke, S. (2011). Predicting outcomes of cancer treatment. 2011 ARCS Scientific Congress.
- Clarke, S. (2011). Update on Neuroendocrine. Endocrine and Oncology Nurses of Australia Symposium.
- Clarke, S. (2011). Use of the neutrophil lymphocyte ratio to predict outcomes from chemotherapy. Medical Oncology Group of Australia Limited Annual Scientific Meeting 2011, Adelaide, South Australia: Medical Oncology Group of Australia.
- Clarke, S. (2010). Evaluating Chemotherapy Toxicity/Antimetabolite Chemotherapy. Medical Oncology Group of Australia Basic Sciences of Oncology Program 2010.
- Clarke, S. (2010). Interacting with Pharma. 2010 Joint MOGA and Private Cancer Physicians of Australia.
- Clarke, S. (2010). lndividualisation of Chemotherapy in Colorectal Cancer. Colorectal Cancer - A Multidisciplinary Approach Meeting.
- Clarke, S. (2010). Options in Academia. Pfizer Advanced Trainee Education Meeting.
- Clarke, S. (2010). Predictors of outcomes in colorectal cancer. Ludwig Institute Colon Cancer Symposium.
- Clarke, S. (2010). Updates in Medical Oncology. 2010 ARCS Australia Annual Scientific Congress.
- Clarke, S. (2009). Advanced colorectal cancer - where are we going? AstraZeneca Challenges in Gastroenterology Symposium.
- Clarke, S. (2009). Chemotherapy and timing of surgery. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009.
- Clarke, S. (2009). Interactions with cancer therapies. Clinical Oncological Society of Australia 36th Annual Scientific Meeting: Awareness, Access, Action.
- Clarke, S. (2009). Managing complex/multiple focus disease areas & networks: the cancer experience. National Institute of Complementary Medicine 2009 National Symposium: Supporting health priorities & industry growth.
- Clarke, S. (2009). Plasma proteomic predictors of response and toxicitv in colorectal cancer patients receiving chemotherapy. 2nd Sino-Australian Symposium, N/A: N/A.
- Clarke, S. (2009). Systemic therapy for Malignant Mesothelioma: An Overview. ANZAC Research Institute’s 8th Annual Symposium.
- Clarke, S. (2008). DaVINCI Trial Update and Issues in 2nd line chemotherapy. 10th Annual Scientific Meeting of Australasian Gastro-Intestinal Trials Group.
- Clarke, S. (2008). Differences in Chemotherapy. 1st Sino-Australian Symposium.
- Clarke, S. (2008). Inflammation and cancer drug metabolism. Sydney Cancer Conference 2008 (SCC2008), Sydney: University of Sydney.
- Clarke, S. (2008). Inflammation, drug metabolism and chemotherapy toxicity. Hunter Medical Research Institute Conference on Translational Cancer Research.
- Clarke, S. (2008). Inflammatory Response: An unrecognized source of variability in PK/PD of cancer chemotherapy. ASCPT 2008 Annual Meeting.
- Clarke, S. (2008). Infusion vs bolus chemotherapy for colon cancer/Stage II Colon Cancer: Is adjuvant chemotherapy necessary? National Cancer Control Network 1st Asian Scientific Meeting.
- Clarke, S. (2008). New developments in the practice of lung cancer. The Oncology Forum of Chinese Physicians from China and the US (OFCCU).
- Clarke, S. (2008). Predicting toxicity from chemotherapy. The Australian Health & Medical Research Congress 2008.
- Sobrero, A., Ackland, S., Perez-Carrion, R., Chiara, S., Clarke, S., Giron, C., Langer, B., Zurlo, A., Young, S. (2006). Efficacy and safety of bevacizumab in combination with irinotecan and infusional 5-FU as first-line treatment for patients with metastatic colorectal cancer. 2006 American Society of Clinical Oncology (ASCO) Annual Meeting, United States: American Society of Clinical Oncology.
- Haller, D., Cassidy, J., Clarke, S., Cunningham, D., Van Cutsem, E., Hoff, P., Rothenberg, M., Saltz, L., Schmoll, H., Twelves, C. (2006). Tolerability of fluoropyrimidines appears to differ by region. 2006 ASCO Annual Meeting, United Kingdom: Oxford University Press.
- Tobin, P., Seale, P., Lee, S., Solomon, M., Fields, S., Rivory, L., Clarke, S. (2005). The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours. 2005 American Society of Clinical Oncology (ASCO) Annual Meeting, United States: American Society of Clinical Oncology.
- Clarke, S., Boyer, M., Stockler, M., Venkatawaran, R., Nordman, I., Joshua, A. (2005). Weekly docetaxel as second line treatment after mitoxantrone for androgen-independent prostate cancer (AIPC). 2005 ASCO Annual Meeting, NY, USA: American Society of Clinical Oncology.
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2024
- Tan, L., Brown, C., Mersiades, T., Lee, C., John, T., Kao, S., Newnham, G., O'Byrne, K., Parakh, S., Bray, V., Yip, S., Clarke, S., Pavlakis, N., Stockler, M., et al (2024). A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nature Communications, 15(1). [More Information]
- Thomsen, M., Vemuri, R., Huygens, F., Clarke, S., Vitetta, L. (2024). An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid. Inflammopharmacology. [More Information]
- Brown, L., Khou, V., Brown, C., Alexander, M., Jayamanne, D., Wei, J., Gray, L., Chan, W., Smith, S., Harden, S., Mersiades, T., Itchins, M., Pavlakis, N., Clarke, S., Boyer, M., Nagrial, A., Hau, E., Esteves Domingues Pires da Silva, I., Kao, S., Kong, B., et al (2024). First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study. Frontiers in Oncology, 14. [More Information]
- De Silva, M., Tse, B., Diakos, C., Clarke, S., Molloy, M. (2024). Immunogenic cell death in colorectal cancer: a review of mechanisms and clinical utility. Cancer Immunology, Immunotherapy, 73(3), 53. [More Information]
- De Silva, M., Pavlakis, N., Schembri, G., Chan, D., Bernard, E., Conner, A., Mascall, S., Bailey, D., Roach, P., Clarke, S., Diakos, C. (2024). Metabolic Tumor Volume on 18-Fluorodeoxyglucose Positron Emission Tomography as a Prognostic Marker of Survival in Patients with Locally Advanced or Metastatic Neuroendocrine Neoplasms Treated with 177Lutetium-DOTA-Octreotate Peptide Receptor Radionuclide Therapy. Pancreas, 53(7), e560-e565. [More Information]
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2023
- Wei, J., Yuile, A., Itchins, M., Kong, B., Li, B., Pavlakis, N., Chan, D., Clarke, S. (2023). Anti-PD-1 Monoclonal Antibodies (mAbs) Are Superior to Anti-PD-L1 mAbs When Combined with Chemotherapy in First-Line Treatment for Metastatic Non-Small Cell Lung Cancer (mNSCLC): A Network Meta-Analysis. Biomedicines, 11(7). [More Information]
- Saltz, L., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2023). Bevacizumab in Combination with Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study. Journal of Clinical Oncology, 41(21), 3663-3669. [More Information]
- Tse, B., Molloy, M., Bergamin, S., Steffen, P., Hruby, G., Pavlakis, N., Clarke, S., Evans, J., Engel, A., Kneebone, A. (2023). CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy. OncoImmunology, 12(1), 2238506. [More Information]
- Bendell, J., LoRusso, P., Overman, M., Noonan, A., Kim, D., Strickler, J., Kim, S., Clarke, S., George, T., Grimison, P., et al (2023). First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors. Cancer Immunology, Immunotherapy, 72(7), 2443-2458. [More Information]
- Mckay, M., Castaneda, M., Catania, S., Charles (nee Slaviero), K., Shanahan, E., Clarke, S., Engel, A., Varelis, P., Molloy, M. (2023). Quantification of short-chain fatty acids in human stool samples by LC-MS/MS following derivatization with aniline analogues. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1217. [More Information]
- Gordon, S., Chan, D., Bernard, E., Eslick, M., Willowson, K., Roach, P., Engel, A., Maher, R., Clarke, S., Agarwal, V., De Silva, M., Conner, A., Pavlakis, N., Bailey, D., et al (2023). Single-centre experience with peptide receptor radionuclide therapy for neuroendocrine tumours (NETs): results using a theranostic molecular imaging-guided approach. Journal of Cancer Research and Clinical Oncology. [More Information]
- Ahmadzada, T., Vijayan, A., Vafaee, F., Azimi, A., Reid, G., Clarke, S., Kao, S., Grau, G., Hosseini Beheshti, E. (2023). Small and Large Extracellular Vesicles Derived from Pleural Mesothelioma Cell Lines Offer Biomarker Potential. Cancers, 15(8). [More Information]
- Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]
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2022
- Itchins, M., Ainsworth, H., Alexander, M., Dean, S., Dharmaraj, D., Pavlakis, N., Clarke, S., Brown, C., Torres, J., Saqib, A., Kao, S., et al (2022). A Multi-Center Real-World Experience of IMpower150 in Oncogene Driven Tumors and CNS Metastases. Clinical Lung Cancer, 23(8), 702-708. [More Information]
- Siu, D., Ali, A., Tjokrowidjaja, A., De Silva, M., Lee, J., Clingan, P., Aghmesheh, M., Brungs, D., Mapagu, C., Goldstein, D., Sjoquist, K., Pavlakis, N., Clarke, S., Diakos, C., et al (2022). Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers. Asia-Pacific Journal of Clinical Oncology, 18(6), 660-668. [More Information]
- Chan, D., Clarke, S., Engel, A., Diakos, C., Pavlakis, N., Roach, P., Bailey, D., Bauer, J., Findlay, M. (2022). Computed tomography (CT)-defined sarcopenia and myosteatosis are prevalent in patients with neuroendocrine neoplasms (NENs) treated with peptide receptor radionuclide therapy (PRRT). European Journal of Clinical Nutrition, 76(1), 143-149. [More Information]
- Bhimani, N., Wong, G., Molloy, C., Pavlakis, N., Diakos, C., Clarke, S., Dieng, M., Hugh, T. (2022). Cost of treating metastatic colorectal cancer: a systematic review. Public Health, 211, 97-104. [More Information]
- Lovell, M., Phillips, J., Luckett, T., Lam, L., Boyle, F., Davidson, P., Cheah, S., McCaffrey, N., Currow, D., Shaw, T., Clarke, S., Lee, J., Clark, K., et al (2022). Effect of Cancer Pain Guideline Implementation on Pain Outcomes Among Adult Outpatients With Cancer-Related Pain: A Stepped Wedge Cluster Randomized Trial. JAMA Network Open, 5(2), e220060-1-e220060-12. [More Information]
- Whittle, K., Kao, S., Clarke, S., Grau, G., Hosseini Beheshti, E. (2022). Exploring the role of extracellular vesicles and their protein cargo in lung cancer metastasis: A review. Critical Reviews in Oncology / Hematology (online), 171, 103603-1-103603-11. [More Information]
- Khin, N., De Silva, M., Clarke, S., Pavlakis, N., Rogan, C., Ho-Shon, K., Lane, R. (2022). Liver Isolation Oxaliplatin (LIOX): Long Term Survival from a New Locoregional Technique for Chemorefractory Patients with Colorectal Liver Metastases. Annals of Surgical Oncology, 29(6), 3387-3389. [More Information]
- Batty, K., Taylor, A., Bernard, E., Diakos, C., Clarke, S., Guminski, A., Baron-Hay, S., Boyle, F., Pavlakis, N., Chan, D. (2022). Metastatic primary breast neuroendocrine neoplasms: a case series. Internal Medicine Journal. [More Information]
- Maharaj, A., Lubel, J., Lam, E., Clark, P., Duncan, O., George, J., Jeffrey, G., Lipton, L., Liu, H., McCaughan, G., Tu, T., et al (2022). Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus. Hepatology Communications, 6(11), 3260-3271. [More Information]
- Clarke, S., Butcher, B., McLachlan, A., Henson, J., Rutolo, D., Hall, S., Vitetta, L. (2022). Pilot clinical and pharmacokinetic study of Δ⁹-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain. PloS One, 17(10 October). [More Information]
- Nahm, C., Turchini, J., Sahni, S., Millar, E., Itchins, M., Arena, J., Cho, A., Colvin, E., Howell, V., Pavlakis, N., Clarke, S., Samra, J., Gill, A., Mittal, A. (2022). The Right Treatment Strategy for the Right Patient: A Biomarker-Driven Approach to Neoadjuvant vs. Surgery-First Management of Resectable and Borderline Resectable Pancreatic Cancer. Cancers, 14(15). [More Information]
- Jambor, M., Ashrafizadeh, A., Nahm, C., Clarke, S., Pavlakis, N., Kneebone, A., Hruby, G., Gill, A., Mittal, A., Samra, J. (2022). The role of staging laparoscopy in pancreatic adenocarcinoma and its effect on patients’ survival. World Journal of Surgical Oncology, 20(1). [More Information]
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2021
- Lubel, J., Roberts, S., Strasser, S., Thompson, A., Philip, J., Goodwin, M., Clarke, S., Crawford, D., Levy, M., Shackel, N. (2021). Australian recommendations for the management of hepatocellular carcinoma: a consensus statement. Medical Journal of Australia, 214(10), 475-483. [More Information]
- Mondaca, S., Lebow, E., Namakydoust, A., Razavi, P., Reis-Filho, J., Shen, R., Offin, M., Tu, H., Murciano-Goroff, Y., Xu, C., Pavlakis, N., Clarke, S., Itchins, M., Lee, A., et al (2021). Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions. Lung Cancer, 159, 66-73. [More Information]
- Leal, J., Alexander, M., Itchins, M., Wright, G., Kao, S., Hughes, B., Pavlakis, N., Clarke, S., Gill, A., Ainsworth, H., et al (2021). EGFR Exon 20 Insertion Mutations: Clinicopathological Characteristics and Treatment Outcomes in Advanced Non–Small Cell Lung Cancer: EGFR Exon 20 Insertion Mutations in NSCLC. Clinical Lung Cancer, 22(6), e859-e869. [More Information]
- Davis, A., Kao, S., Clarke, S., Boyer, M., Pavlakis, N. (2021). Emerging biological therapies for the treatment of malignant pleural mesothelioma. Expert Opinion on Emerging Drugs, 26(2), 179-192. [More Information]
- Oh, B., Boyle, F., Pavlakis, N., Clarke, S., Guminski, A., Eade, T., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Hruby, G., Stevens, M., Molloy, M., Back, M., et al (2021). Emerging Evidence of the Gut Microbiome in Chemotherapy: A Clinical Review. Frontiers in Oncology, 11, 706331. [More Information]
- Gordon, E., Chan, D., Arena, J., Bernard, E., Carr-Boyd, E., Clarke, S., Itchins, M., Learoyd, D., Sandanayake, N., Pavlakis, N. (2021). Life-threatening diarrhea in neuroendocrine tumors: two case reports. Journal of Medical Case Reports, 15(1), 542. [More Information]
- Davis, A., Clarke, S., Ayesa, S., Chan, D. (2021). Marked improvement in hyperammonaemic encephalopathy from multimodal treatment of metastatic neuroendocrine tumour. BMJ Case Reports, 14(6), e241191-1-e241191-4. [More Information]
- Maloney, S., Itchins, M., Arena, J., Sahni, S., Howell, V., Hayes, S., Gill, A., Clarke, S., Samra, J., Mittal, A., Pavlakis, N. (2021). Optimal Upfront Treatment in Surgically Resectable Pancreatic Cancer Candidates: A High-Volume Center Retrospective Analysis. Journal of Clinical Medicine, 10(12), 2700. [More Information]
- Ding, P., Roberts, T., Chua, W., Becker, T., Caixeiro, N., de Souza, P., Gao, B., Lee, C., Itchins, M., Westman, H., Clarke, S., Bray, V., et al (2021). Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib. Translational Lung Cancer Research, 10(4), 1623-1634. [More Information]
- Liu, J., Itchins, M., Nagrial, A., Cooper, W., De Silva, M., Barnet, M., Varikatt, W., Sivasubramaniam, V., Davis, A., Gill, A., Blinman, P., Lee, K., Hui, R., Pavlakis, N., Clarke, S., Boyer, M., Kao, S., et al (2021). Relationship between PD-L1 expression and outcome in EGFR-mutant lung cancer patients treated with EGFR tyrosine kinase inhibitors. Lung Cancer, 155, 28-33. [More Information]
- Illini, O., Hochmair, M., Fabikan, H., Weinlinger, C., Tufman, A., Swalduz, A., Lamberg, K., Hashemi, S., Huemer, F., Vikström, A., et al (2021). Selpercatinib in RET fusion-positive non-small-cell lung cancer (SIREN): a retrospective analysis of patients treated through an access program. Therapeutic Advances in Medical Oncology, 13. [More Information]
- Wijetunga, A., Chua, T., Nahm, C., Pavlakis, N., Clarke, S., Chan, D., Diakos, C., Maloney, S., Ashrafi-Zadeh, A., Kneebone, A., Gill, A., Mittal, A., Samra, J., et al (2021). Survival in borderline resectable and locally advanced pancreatic cancer is determined by the duration and response of neoadjuvant therapy: Survival in advanced pancreatic cancer. European Journal of Surgical Oncology, 47(10), 2543-2550. [More Information]
- Oh, B., Boyle, F., Pavlakis, N., Clarke, S., Eade, T., Hruby, G., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Stevens, M., Molloy, M., Kong, B., Back, M., et al (2021). The gut microbiome and cancer immunotherapy: Can we use the gut microbiome as a predictive biomarker for clinical response in cancer immunotherapy? Cancers, 13(19), 4824. [More Information]
- Oh, B., Eade, T., Lamoury, G., Carroll, S., Morgia, M., Kneebone, A., Hruby, G., Stevens, M., Boyle, F., Clarke, S., Molloy, M., Back, M., et al (2021). The gut microbiome and gastrointestinal toxicities in pelvic radiation therapy: A clinical review. Cancers, 13(10), 2353. [More Information]
- Bhimani, N., Brown, K., Kelly, P., Molloy, C., Xue, A., Clarke, S., Rasmussen, H., Hugh, T. (2021). The prognostic significance of tumour FXYD-3 expression in patients with primary and secondary colorectal cancers. Frontiers in Gastroenterology & Hepatology, 1(1), 1-10. [More Information]
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2020
- Alexander, M., Pavlakis, N., John, T., O'Connell, R., Kao, S., Hughes, B., Lee, A., Hayes, S., Howell, V., Clarke, S., Itchins, M., et al (2020). A multicenter study of thromboembolic events among patients diagnosed with ROS1-rearranged non-small cell lung cancer. Lung Cancer, 142, 34-40. [More Information]
- Itchins, M., Lau, B., Hudson, A., Westman, H., Xia, C., Hayes, S., Howell, V., Rodriguez, M., Cooper, W., Wei, G., Buckland, M., Li, B., Gill, A., Clarke, S., Pavlakis, N., et al (2020). ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 25(8), 641-649. [More Information]
- Sagnella, S., Yang, L., Stubbs, G., Boslem, E., Martino-Echarri, E., Smolarczyk, K., Pattison, S., Vanegas, N., St. Clair, E., Clarke, S., et al (2020). Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells. Cancer Cell, 37(3), 354-3.70. [More Information]
- Smith-Uffen, M., Johnson, S., Martin, A., Tattersall, M., Stockler, M., Bell, M., Detering, K., Clayton, J., Silvester, W., Clarke, S., Vaccaro, L., Beale, P., Kiely, B. (2020). Estimating survival in advanced cancer: a comparison of estimates made by oncologists and patients. Supportive Care in Cancer, 28(7), 3399-3407. [More Information]
- Itchins, M., Chua, T., Arena, J., Jamieson, N., Nahm, C., O'Connell, R., Bailey, E., Schembri, G., Gill, A., Kneebone, A., Hruby, G., Mittal, A., Pavlakis, N., Clarke, S., Samra, J. (2020). Evaluation of Fluorodeoxyglucose Positron Emission Tomography Scanning in the Neoadjuvant Therapy Paradigm in Pancreatic Ductal Adenocarcinoma. Pancreas, 49(2), 224-229. [More Information]
- Ahmadzada, T., Kao, S., Reid, G., Clarke, S., Grau, G., Hosseini Beheshti, E. (2020). Extracellular vesicles as biomarkers in malignant pleural mesothelioma: A review. Critical Reviews in Oncology / Hematology (online), 150, 102949. [More Information]
- Chan, D., Bernard, E., Schembri, G., Roach, P., Johnson, M., Pavlakis, N., Clarke, S., Bailey, D. (2020). High Metabolic Tumour Volume on 18-Fluorodeoxyglucose Positron Emission Tomography Predicts Poor Survival from Neuroendocrine Neoplasms. Neuroendocrinology, 110(11-12), 950-958. [More Information]
- Sahni, S., Nahm, C., Krisp, C., Molloy, M., Mehta, S., Maloney, S., Itchins, M., Pavlakis, N., Clarke, S., Chan, D., Gill, A., Howell, V., Samra, J., Mittal, A. (2020). Identification of Novel Biomarkers in Pancreatic Tumor Tissue to Predict Response to Neoadjuvant Chemotherapy. Frontiers in Oncology, 10, 1-10. [More Information]
- Harris, B., Phan, V., Perera, V., Szyc, A., Galettis, P., Martin, J., Walpole, E., McLachlan, A., Clarke, S., Reuter, S., Charles (nee Slaviero), K. (2020). Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes. Clinical Pharmacokinetics, 59(8), 1013-1026. [More Information]
- Lyu, N., Rajendran, V., Diefenbach, R., Charles (nee Slaviero), K., Clarke, S., Engel, A., Rizos, H., Molloy, M., Wang, Y. (2020). Multiplex detection of ctdna mutations in plasma of colorectal cancer patients by pcr/sers assay. Nanotheranostics, 4(4), 224-232. [More Information]
- Karsten, E., Breen, E., McCracken, S., Clarke, S., Herbert, B. (2020). Red blood cells exposed to cancer cells in culture have altered cytokine profiles and immune function. Scientific Reports, 10(1), 7727. [More Information]
- Ahmadzada, T., Cooper, W., Holmes, M., Mahar, A., Westman, H., Gill, A., Nordman, I., Yip, P., Pal, A., Zielinski, R., Pavlakis, N., Nagrial, A., Daneshvar, D., Karikios, D., Grau, G., Hosseini Beheshti, E., Clarke, S., Kao, S., et al (2020). Retrospective evaluation of the use of pembrolizumab in malignant mesothelioma in a real-world Australian population. JTO Clinical and Research Reports, 1(4), 1-15. [More Information]
- Ackland, S., Michael, M., de Souza, P., Martin, J., Clarke, S., Francis, K., Karapetis, C., Gurney, H. (2020). Science and art of anticancer drug dosing: nine steps to personalised therapy. Internal Medicine Journal, 50(8), 992-996. [More Information]
- Chan, J., Diakos, C., Engel, A., Chan, D., Pavlakis, N., Gill, A., Clarke, S. (2020). Serum bicarbonate is a marker of perioperative mortality but is not associated with long term survival in colorectal cancer. PloS One, 15(1), 1-14. [More Information]
- McKelvey, K., Hudson, A., Kumar, R., Eade, T., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Sub-acute Toxicity in Non-cancerous Tissue and Immune-Related Adverse Events of a Novel Combination Therapy for Cancer. Frontiers in Oncology, 9, 1504. [More Information]
- McKelvey, K., Hudson, A., Kumar, R., Wilmott, J., Attrill, G., Long, G., Scolyer, R., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model. PloS One, 15(4), e0226444. [More Information]
- Jang, A., Brown, C., Lamoury, G., Morgia, M., Boyle, F., Marr, I., Clarke, S., Back, M., Oh, B. (2020). The Effects of Acupuncture on Cancer-Related Fatigue: Updated Systematic Review and Meta-Analysis. Integrative Cancer Therapies, 19. [More Information]
- Oh, B., Bae, K., Lamoury, G., Eade, T., Boyle, F., Corless, B., Clarke, S., Yeung, A., Rosenthal, D., Schapira, L., Back, M. (2020). The Effects of Tai Chi and Qigong on Immune Responses: A Systematic Review and Meta-Analysis. Medicines, 7(7), 39. [More Information]
- Tjokrowidjaja, A., Goldstein, D., Hudson, M., Lord, S., Gebski, V., Clarke, S., de Souza, P., Motzer, R., Lee, C. (2020). The impact of neutrophil-lymphocyte ratio on risk reclassification of patients with advanced renal cell cancer to guide risk-directed therapy. Acta Oncologica, 59(1), 20-27. [More Information]
- Clarke, S., Burge, M., Feeney, K., Gibbs, P., Jones, K., Marx, G., Molloy, M., Price, T., Reece, W., Segelov, E., et al (2020). The prognostic role of inflammatory markers in patients with metastatic colorectal cancer treated with bevacizumab: A translational study [ASCENT]. PloS One, 15(3), e0229900. [More Information]
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2019
- Sabari, J., Offin, M., Stephens, D., Ni, A., Lee, A., Pavlakis, N., Clarke, S., Diakos, C., Datta, S., Tandon, N., et al (2019). A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers. Journal of the National Cancer Institute, 111(6), 1-9. [More Information]
- Lai, W., Lebas, L., Barnes, T., Milia, J., Gautschi, O., Ni, A., Peters, S., Ferrara, R., Plodkowski, A., Kavanagh, J., Clarke, S., Pavlakis, N., et al (2019). Afatinib in patients with metastatic or recurrent HER2-mutant lung cancers: a retrospective international multicentre study. European Journal of Cancer, 109, 28-35. [More Information]
- Trousil, S., Lee, P., Edwards, R., Maslen, L., Lozan‐Kuehne, J., Ramaswami, R., Aboagye, E., Clarke, S., Liddle, C., Sharma, R. (2019). Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation. British Journal of Pharmacology, 176(18), 3712-3722. [More Information]
- Nahm, C., Turchini, J., Jamieson, N., Moon, E., Sioson, L., Itchins, M., Arena, J., Colvin, E., Howell, V., Pavlakis, N., Clarke, S., Samra, J., Gill, A., Mittal, A. (2019). Biomarker panel predicts survival after resection in pancreatic ductal adenocarcinoma: A multi-institutional cohort study. European Journal of Surgical Oncology, 45(2), 218-224. [More Information]
- Ahmadzada, T., Lee, K., Clarke, C., Cooper, W., Linton, A., McCaughan, B., Asher, R., Clarke, S., Reid, G., Kao, S. (2019). High BIN1 expression has a favorable prognosis in malignant pleural mesothelioma and is associated with tumor infiltrating lymphocytes. Lung Cancer, 130, 35-41. [More Information]
- Back, M., Jayamanne, D., Brazier, D., Newey, A., Bailey, D., Schembri, G., Hsiao, E., Khasraw, M., Wong, M., Kastelan, M., Clarke, S., Wheeler, H., et al (2019). Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management. Journal of Medical Imaging and Radiation Oncology, 63(2), 272-280. [More Information]
- Shinko, D., McGuire, H., Diakos, C., Pavlakis, N., Clarke, S., Byrne, S., Charles (nee Slaviero), K. (2019). Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients. Frontiers in Immunology, 10, 1-12. [More Information]
- Currey, N., Jahan, Z., Caldon, E., Tran, P., Benthani, F., De Lacavalerie, P., Roden, D., Gloss, B., Campos, C., Bean, E., Clarke, S., et al (2019). Mouse Model of 'Mutated in Colorectal Cancer' Gene Deletion Reveals Novel Pathways in Inflammation and Cancer. Cellular and Molecular Gastroenterology and Hepatology, 7(4), 819-839. [More Information]
- Janssen, Q., Buettner, S., Suker, M., Beumer, B., Addeo, P., Bachellier, P., Bahary, N., Bekaii-Saab, T., Bali, M., Besselink, M., Clarke, S., Samra, J., et al (2019). Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis. Journal of the National Cancer Institute, 111(8), 782-794. [More Information]
- Javle, M., Borbath, I., Clarke, S., Hitre, E., Louvet, C., Macarulla, T., Oh, D., Spratlin, J., Valle, J., Weiss, K., et al (2019). Phase 3 multicenter, open-label, randomized study of infigratinib versus gemcitabine plus cisplatin in the first-line treatment of patients with advanced cholangiocarcinoma with FGFR2 gene fusions/translocations: the PROOF trial. Annals of Oncology, 30(Supplement 4). [More Information]
- Learoyd, D., Clarke, S. (2019). Straddling medical specialties: should we have more comprehensive advanced training? Internal Medicine Journal, 49(5), 669-671. [More Information]
- Vitetta, L., Chen, J., Clarke, S. (2019). The vermiform appendix: an immunological organ sustaining a microbiome inoculum. Clinical Science, 133(1), 1-8. [More Information]
- Kwok, G., Zhao, J., Glover, A., Ip, J., Sywak, M., Clifton-Bligh, R., Clarke, S., Robinson, B., Sidhu, S. (2019). Treatment and management of adrenal cancer in a specialized Australian endocrine surgical unit: approaches, outcomes and lessons learnt. ANZ Journal of Surgery, 89(1-2), 48-52. [More Information]
- Chan, J., Diakos, C., Engel, A., Chan, D., Pavlakis, N., Gill, A., Clarke, S. (2019). Tumor sidedness is not an independent prognostic marker of colorectal cancer patients undergoing curative resection: A retrospective cohort study. PloS One, 14(6), 1-15. [More Information]
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2018
- Vafaee, F., Diakos, C., Kirschner, M., Reid, G., Michael, M., Horvath, L., Alinejad-Rokny, H., Cheng, Z., Kuncic, Z., Clarke, S. (2018). A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis. Npj Systems Biology And Applications, 4, 20. [More Information]
- Chan, J., Diakos, C., Chan, D., Engel, A., Pavlakis, N., Gill, A., Clarke, S. (2018). A Longitudinal Investigation of Inflammatory Markers in Colorectal Cancer Patients Perioperatively Demonstrates Benefit in Serial Remeasurement. Annals of Surgery, 267(6), 1119-1125. [More Information]
- Johnson, S., Butow, P., Bell, M., Detering, K., Clayton, J., Silvester, W., Kiely, B., Clarke, S., Vaccaro, L., Stockler, M., Tattersall, M., et al (2018). A randomised controlled trial of an advance care planning intervention for patients with incurable cancer. British Journal of Cancer, 119(10), 1182-1190. [More Information]
- Oh, B., Yeung, A., Klein, P., Larkey, L., Ee, C., Zaslawski, C., Knobf, M., Payne, P., Stener-Victorin, E., Lee, R., Pavlakis, N., Boyle, F., Clarke, S., Back, M., et al (2018). Accreditation Standard Guideline Initiative for Tai Chi and Qigong Instructors and Training Institutions. Medicines, 5(2), 51. [More Information]
- Oh, B., Eade, T., Kneebone, A., Hruby, G., Lamoury, G., Pavlakis, N., Clarke, S., Zaslawski, C., Marr, I., Costa, D., Back, M. (2018). Acupuncture in Oncology: The Effectiveness of Acupuncture May Not Depend on Needle Retention Duration. Integrative Cancer Therapies, 17(2), 458-466. [More Information]
- Li, B., Shen, R., Buonocore, D., Olah, Z., Ni, A., Ginsberg, M., Ulaner, G., Offin, M., Feldman, D., Hembrough, T., Pavlakis, N., Clarke, S., et al (2018). Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial. Journal of Clinical Oncology, 36(24), 2532-2537. [More Information]
- Lane, R., Khin, N., Pavlakis, N., Hugh, T., Clarke, S., Magnussen, J., Rogan, C., Flekser, R. (2018). Challenges in chemotherapy delivery: comparison of standard chemotherapy delivery to locoregional vascular mass fluid transfer. Future Oncology, 14(7), 647-663. [More Information]
- Wong, E., Jacques, S., Bennett, M., Gorolay, V., Lee, A., Clarke, S. (2018). Complete response in a patient with stage IV adrenocortical carcinoma treated with adjuvant trans-catheter arterial chemo-embolization (TACE). Asia-Pacific Journal of Clinical Oncology, 14(3), 279-281. [More Information]
- Itchins, M., Clarke, S., Pavlakis, N. (2018). Do EGFR tyrosine kinase inhibitors (TKIs) still have a role in EGFR wild-type pre-treated advanced non-small cell lung cancer (NSCLC)?-the shifting paradigm of therapeutics. Translational Lung Cancer Research, 7(Suppl 1), S39-S45. [More Information]
- Yu, S., Arima, H., Bertmar, C., Clarke, S., Herkes, G., Krause, M. (2018). Neutrophil to lymphocyte ratio and early clinical outcomes in patients with acute ischemic stroke. Journal of the Neurological Sciences, 387, 115-118. [More Information]
- Leyden, J., Pavlakis, N., Chan, D., Michael, M., Clarke, S., Khasraw, M., Price, T. (2018). Patient-reported experience of the impact and burden of neuroendocrine tumors:Oceania patient results from a large global survey. Asia-Pacific Journal of Clinical Oncology, 14(3), 256-263. [More Information]
- Itchins, M., Hayes, S., Gill, A., Cooper, W., O'Connell, R., Howell, V., Clarke, S., Pavlakis, N. (2018). Pattern of care and survival of anaplastic lymphoma kinase rearranged non-small cell lung cancer (ALK+ NSCLC) in an Australian Metropolitan Tertiary Referral Centre: A retrospective cohort analysis. Asia-Pacific Journal of Clinical Oncology, 14(5), e275-e282. [More Information]
- Itchins, M., Arena, J., Pavlakis, N., Nahm, C., Gibbs, E., Mohamudally, A., Maher, R., Bailey, D., Schembri, G., Gill, A., Diakos, C., Khasraw, M., Hruby, G., Kneebone, A., Mittal, A., Samra, J., Clarke, S., et al (2018). Pattern of care and survival of pancreatic ductal adenocarcinoma in a multi-disciplinary high-volume centre. Gastroenterology & Hepatology, 9(5), 185-189. [More Information]
- Sjoquist, K., Renfro, L., Simes, R., Tebbutt, N., Clarke, S., Seymour, M., Adams, R., Maughan, T., Saltz, L., Goldberg, R., et al (2018). Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 110(6), 638-648. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Renton, C., Clarke, S., Tannock, I. (2018). Prognostic indices of inflammatory markers, cognitive function and fatigue for survival in patients with localised colorectal cancer. ESMO Open, 3, e000302. [More Information]
- Chou, A., Froio, D., Nagrial, A., Parkin, A., Murphy, K., Chin, V., Wohl, D., Steinmann, A., Stark, R., Drury, A., Clarke, S., Gill, A., et al (2018). Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer. Gut, 67(12), 2142-2155. [More Information]
- Lane, R., Khin, N., Rogan, C., Magnussen, J., Ho-Shon, K., Pavlakis, N., Clarke, S., Hugh, T. (2018). The integration of pharmacology and pathophysiology into locoregional chemotherapy delivery via mass fluid transfer. Journal of Controlled Release, 292, 18-28. [More Information]
- Thomsen, M., Clarke, S., Vitetta, L. (2018). The role of adjuvant probiotics to attenuate intestinal inflammatory responses due to cancer treatments. Beneficial Microbes, 9(6), 899-916. [More Information]
- Hayes, S., Clarke, S., Pavlakis, N., Howell, V. (2018). The role of proteomics in the age of immunotherapies. Mammalian Genome, 29, 757-769. [More Information]
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2017
- Johnson, S., Butow, P., Bell, M., Detering, K., Clayton, J., Silvester, W., Kiely, B., Clarke, S., Vaccaro, L., Stockler, M., Beale, P., Fitzgerald, N., Tattersall, M. (2017). A Randomized Controlled Trial of an Advance Care Planning Intervention for Patients with Incurable Cancer. The 44th Clinical Oncological Society of Australia Annual Scientific Meeting,.
- John, T., Bowden, J., Clarke, S., Fox, S., Garrett, K., Horwood, K., Karapetis, C. (2017). Australian recommendations for EGFR T790M testing in advanced non-small cell lung cancer. Asia-Pacific Journal of Clinical Oncology, 13(4), 296-303. [More Information]
- Shinko, D., Diakos, C., Clarke, S., Charles (nee Slaviero), K. (2017). Cancer-Related Systemic Inflammation: The Challenges and Therapeutic Opportunities for Personalized Medicine. Clinical Pharmacology & Therapeutics, 102(4), 599-610. [More Information]
- Willowson, K., Bernard, E., Maher, R., Clarke, S., Bailey, D. (2017). Changing Therapeutic Paradigms: Predicting mCRC Lesion Response to Selective Internal Radionuclide Therapy (SIRT) based on Critical Absorbed Dose Thresholds: A Case Study. Asia Oceania Journal of Nuclear Medicine & Biology, 5(1), 66-69. [More Information]
- Willowson, K., Hayes, A., Chan, D., Tapner, M., Bernard, E., Maher, R., Pavlakis, N., Clarke, S., Bailey, D. (2017). Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis. EJNMMI Research, 7(1), 1-13. [More Information]
- Chan, D., Pavlakis, N., Schembri, G., Bernard, E., Hsiao, E., Hayes, A., Barnes, T., Diakos, C., Khasraw, M., Samra, J., Eslick, E., Roach, P., Engel, A., Clarke, S., Bailey, D. (2017). Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: proposal for a Novel Grading Scheme with Prognostic Significance. Theranostics, 7(5), 1149-1158. [More Information]
- Oh, B., Eade, T., Kneebone, A., Pavlakis, N., Clarke, S., Eslick, G., River, J., Back, M. (2017). Factors affecting whether or not cancer patients consider using acupuncture. Acupuncture in Medicine, 35(2), 107-113. [More Information]
- Dhillon, H., Bell, M., van der Ploeg, H., Turner, J., Kabourakis, M., Spencer, L., Lewis, C., Hui, R., Blinman, P., Clarke, S., Boyer, M., Vardy, J. (2017). Impact of physical activity on fatigue and quality of life in people with advanced lung cancer: A randomized controlled trial. Annals of Oncology, 28(8), 1889-1897. [More Information]
- Tio, M., Tsui, P., Fischer, G., Clarke, S. (2017). Osimertinib induced bullous dermatitis. Cancer Treatment and Research Communications, 13, 25-26. [More Information]
- Kim, S., Itchins, M., Arena, J., Nahm, C., Pavlakis, N., Clarke, S., Gill, A., Samra, J., Mittal, A. (2017). Patterns and Determinants of Recurrence for Pancreatic Ductal Adenocarcinoma after Resection. Journal of the Pancreas, 18(6), 458-464.
- Chan, D., Clarke, S., Diakos, C., Roach, P., Bailey, D., Singh, S., Pavlakis, N. (2017). Prognostic and predictive biomarkers in neuroendocrine tumours. Critical Reviews in Oncology/Hematology, 113, 268-282. [More Information]
- Itchins, M., Arena, J., Nahm, C., Rabindran, J., Kim, S., Gibbs, E., Bergamin, S., Chua, T., Gill, A., Maher, R., Diakos, C., Mittal, A., Hruby, G., Kneebone, A., Pavlakis, N., Samra, J., Clarke, S., et al (2017). Retrospective cohort analysis of neoadjuvant treatment and survival in resectable and borderline resectable pancreatic ductal adenocarcinoma in a high volume referral centre. European Journal of Surgical Oncology, 43(9), 1711-1717. [More Information]
- van Zandwijk, N., Pavlakis, N., Kao, S., Linton, A., Boyer, M., Clarke, S., Huynh, Y., Chrzanowska, A., Fulham, M., Bailey, D., Cooper, W., Kritharides, L., Reid, G., et al (2017). Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study. The Lancet Oncology, 18(10), 1386-1396. [More Information]
- Selinger, C., Li, B., Pavlakis, N., Links, M., Gill, A., Lee, A., Clarke, S., Tran, T., Lum, T., Yip, P., Horvath, L., Yu, B., O'Toole, S., Cooper, W., et al (2017). Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target. Histopathology, 70(3), 402-411. [More Information]
- Lee, A., Chan, D., Wong, M., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2017). Systematic Review of the Role of Targeted Therapy in Metastatic Neuroendocrine Tumors. Neuroendocrinology, 104(3), 209-222. [More Information]
- Chan, J., Chan, D., Diakos, C., Engel, A., Pavlakis, N., Gill, A., Clarke, S. (2017). The Lymphocyte-to-Monocyte Ratio is a Superior Predictor of Overall Survival in Comparison to Established Biomarkers of Resectable Colorectal Cancer. Annals of Surgery, 265(3), 539-546. [More Information]
- Itchins, M., Chia, P., Hayes, S., Howell, V., Gill, A., Cooper, W., John, T., Mitchell, P., Millward, M., Clarke, S., Pavlakis, N., et al (2017). Treatment of ALK-rearranged non-small cell lung cancer: A review of the landscape and approach to emerging patterns of treatment resistance in the Australian context. Asia-Pacific Journal of Clinical Oncology, 13, 3-13. [More Information]
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2016
- Kao, S., Kirschner, M., Cooper, W., Tran, T., Burgers, S., Wright, C., Korse, T., van den Broek, D., Edelman, J., Vallely, M., McCaughan, B., Pavlakis, N., Clarke, S., van Zandwijk, N., Reid, G., et al (2016). A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma. British Journal of Cancer, 114(5), 524-531. [More Information]
- Vaccaro, L., Johnson, S., Kiely, B., Clayton, J., Clarke, S., Beale, P., Silvester, W., Detering, K., Butow, P., Tattersall, M. (2016). Acceptability of tailored life-expectancy information in patients with advanced cancer participating in an Australian nurse-led ACP RCT. The 43nd Clinical Oncological Society of Australia Annual Scientific Meeting,.
- Johnson, S., Clayton, J., Butow, P., Silvester, W., Detering, K., Hall, J., Kiely, B., Cebon, J., Clarke, S., Bell, M., Stockler, M., Tattersall, M., et al (2016). Advance care planning in patients with incurable cancer: Study protocol for a randomised controlled trial. BMJ Open, 6(12), 1-10. [More Information]
- Song, X., Amirkhani, A., Wu, J., Pascovici, D., Zaw, T., Xavier, D., Clarke, S., Molloy, M. (2016). Analytical performance of nano-LC-SRM using nondepleted human plasma over an 18-month period. Proteomics, 16(15-16), 2118-2127. [More Information]
- Reid, G., Kao, S., Pavlakis, N., Brahmbhatt, H., MacDiarmid, J., Clarke, S., Boyer, M., van Zandwijk, N. (2016). Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer. Epigenomics, 8(8), 1079-1085. [More Information]
- Sclafani, F., Kim, T., Cunningham, D., Kim, T., Tabernero, J., Schmoll, H., Roh, J., Kim, S., Park, Y., Guren, T., Clarke, S., et al (2016). Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial. International Journal of Cancer, 140(2), 431-439. [More Information]
- Malalasekera, M., Tan, C., Phan, V., Yip, P., Vardy, J., Clarke, S., Kao, S. (2016). Eastern Cooperative Oncology Group score: Agreement between non-small-cell lung cancer patients and their oncologists and clinical implications. Cancer Treatment Communications, 5, 17-21. [More Information]
- Hayes, S., Haefliger, S., Harris, B., Pavlakis, N., Clarke, S., Molloy, M., Howell, V. (2016). Exhaled breath condensate for lung cancer protein analysis: a review of methods and biomarkers. Journal of Breath Research, 10(3), 1-26. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Renton, C., Dodd, A., Zhang, H., Clarke, S., Tannock, I. (2016). Fatigue in people with localized colorectal cancer who do and do not receive chemotherapy: a longitudinal prospective study. Annals of Oncology, 27(9), 1761-1767. [More Information]
- Oh, B., Figtree, G., Costa, D., Eade, T., Hruby, G., Lim, S., Elfiky, A., Martine, N., Rosenthal, D., Clarke, S., Back, M. (2016). Oxidative stress in prostate cancer patients: A systematic review of case control studies. Prostate International, 4(3), 71-87. [More Information]
- Bailey, D., Lee, A., Li, B., Clarke, S. (2016). PET monitoring of liver directed selective internal radionuclide therapy for metastatic gastro-oesophageal cancer. BMJ Case Reports, 2016, bcr2016215645. [More Information]
- Wong, E., Oh, L., Nahar, K., Lee, A., Clarke, S. (2016). Primary Pericardial Sarcoma with Right Atrial Invasion and Multiple Bilateral Pulmonary Metastases in a Patient with Hereditary Nonpolyposis Colorectal Cancer. Case Reports in Oncological Medicine, 2016. [More Information]
- Lane, R., Khin, N., Rogan, C., Magnussen, J., Pavlakis, N., Lane, D., Clarke, S. (2016). Safety and Feasibility of Repeatable Hepatic Vascular Isolation Chemotherapy: A Pilot Study. Annals of Surgical Oncology, 23(11), 3699-3708. [More Information]
- Dong, S., Costa, D., Butow, P., Lovell, M., Agar, M., Velikova, G., Teckle, P., Jaure, A., Tebbutt, N., Clarke, S., King, M., et al (2016). Symptom Clusters in Advanced Cancer Patients: An Empirical Comparison of Statistical Methods and the Impact on Quality of Life. Journal of Pain and Symptom Management, 51(1), 88-98. [More Information]
- Wong, M., Chan, D., Lee, A., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2016). Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET). PloS One, 11(6), 1-15. [More Information]
- Charles (nee Slaviero), K., Harris, B., Haddad, C., Clarke, S., Guminski, A., Stevens, M., Dodds, T., Gill, A., Back, M., Veivers, D., Eade, T. (2016). Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and nonoropharyngeal patients. BMC Cancer, 16(1), 1-13. [More Information]
- Li, B., Barnes, T., Chan, D., Naidoo, J., Lee, A., Khasraw, M., Marx, G., Kris, M., Clarke, S., Drilon, A., Pavlakis, N., et al (2016). The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials. Lung Cancer, 102, 21-27. [More Information]
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2015
- Kao, S., Fulham, M., Wong, K., Cooper, W., Brahmbhatt, H., MacDiarmid, J., Pattison, S., Sagong, J., Huynh, Y., Leslie, F., Pavlakis, N., Clarke, S., Boyer, M., Reid, G., van Zandwijk, N. (2015). A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma. American Journal of Respiratory and Critical Care Medicine, 191(12), 1467-1469. [More Information]
- Furtado, R., Ha, L., Clarke, S., Sandroussi, C. (2015). Adjuvant Iodine (131) Lipiodol after Resection of Hepatocellular Carcinoma. Journal of Oncology, 2015, 1-7. [More Information]
- Diakos, C., Charles (nee Slaviero), K., Chua, W., Howell, V., Clarke, S. (2015). Biomarkers in Metastatic Colorectal Cancer. In Victor R. Preedy and Vinood B. Patel (Eds.), Biomarkers in Cancer, (pp. 601-629). Dordrecht: Springer. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Rourke, S., Bekele, T., Renton, C., Dodd, A., Zhang, H., Beale, P., Clarke, S., et al (2015). Cognitive Function in Patients With Colorectal Cancer Who Do and Do Not Receive Chemotherapy: A Prospective, Longitudinal, Controlled Study. Journal of Clinical Oncology, 33(34), 4085-4092. [More Information]
- Park, W., Li, B., Maher, R., Samra, J., Clarke, S., Bernard, E., Bailey, D., Pavlakis, N. (2015). Dramatic response to selective internal radiation therapy for unresectable hepatocellular carcinoma. Oxford Medical Case Reports, 2015 (2), 194-195. [More Information]
- Kao, S., van Zandwijk, N., Clarke, S., Vardy, J., Lumba, S., Tognela, A., Ng, W. (2015). Estimation of an optimal chemotherapy utilization rate for malignant pleural mesothelioma: An evidence-based benchmark for cancer care. Asia-Pacific Journal of Clinical Oncology, 11, 85-92. [More Information]
- Ip, J., Pang, T., Glover, A., Soon, P., Zhao, J., Clarke, S., Robinson, B., Gill, A., Sidhu, S. (2015). Immunohistochemical validation of overexpressed genes identified by global expression microarrays in adrenocortical carcinoma reveals potential predictive and prognostic biomarkers. The Oncologist, 20(3), 247-256. [More Information]
- Ip, J., Pang, T., Glover, A., Soon, P., Clarke, S., Richardson, A., Campbell, P., Robinson, B., Sidhu, S. (2015). Improving Outcomes in Adrenocortical Cancer: An Australian Perspective. Annals of Surgical Oncology, 22(7), 2309-2316. [More Information]
- Zardawi, S., Li, B., Zauderer, M., Wang, J., Atmore, B., Barnes, T., Pavlakis, N., Mathur, M., Clarke, S. (2015). Localized malignant pleural mesothelioma with renal metastasis. Oxford Medical Case Reports, 2015 (1), 170-172. [More Information]
- Glover, A., Zhao, J., Gill, A., Weiss, J., Mugridge, N., Kim, E., Feeney, A., Ip, J., Reid, G., Clarke, S., Robinson, B., Sidhu, S., et al (2015). microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma. Oncotarget, 6(34), 36675-36688. [More Information]
- Michael, M., White, S., Abdi, E., Nott, L., Clingan, P., Zimet, A., Button, P., Gregory, D., Solomon, B., Dobrovic, A., Clarke, S., et al (2015). Multicenter randomized, open-label phase II trial of sequential erlotinib and gemcitabine compared with gemcitabine monotherapy as first-line therapy in elderly or ECOG PS two patients with advanced NSCLC. Asia-Pacific Journal of Clinical Oncology, 11(1), 4-14. [More Information]
- Haddad, C., Guo, L., Clarke, S., Guminski, A., Back, M., Eade, T. (2015). Neutrophil-to-lymphocyte ratio in head and neck cancer. Journal of Medical Imaging and Radiation Oncology, 59(4), 514-519. [More Information]
- Chan, D., Clarke, S., Gill, A., Chantrill, L., Samra, J., Li, B., Barnes, T., Nahar, K., Pavlakis, N. (2015). Pathogenic PALB2 mutation in metastatic pancreatic adenocarcinoma and neuroendocrine tumour: A case report. Molecular and Clinical Oncology, 3(4), 817-819. [More Information]
- McLachlan, A., Clarke, S. (2015). Phytotherapies: Drug Interactions in Cancer. In Not known (Eds.), Phytotherapies: Efficacy, Safety, and Regulation, (pp. 536-553). TBC. [More Information]
- Jankova, L., Dent, O., Molloy, M., Chan, C., Chapuis, P., Howell, V., Clarke, S. (2015). Reporting in studies of protein biomarkers of prognosis in colorectal cancer in relation to the REMARK guidelines. Proteomics - Clinical Applications, 9(11-12), 1078-1086. [More Information]
- Mehta, S., de Reuver, P., Gill, P., Andrici, J., D'Urso, L., Mittal, A., Pavlakis, N., Clarke, S., Samra, J., Gill, A. (2015). Somatostatin Receptor SSTR-2a Expression Is a Stronger Predictor for Survival Than Ki-67 in Pancreatic Neuroendocrine Tumors. Medicine, 94(40), 1-6. [More Information]
- Zhou, J., Belov, L., Chapuis, P., Chan, C., Armstrong, N., Alexander, K., Solomon, M., Clarke, S., Christopherson, R. (2015). Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. Journal of Immunological Methods, 416, 59-68. [More Information]
- Tan, C., Read, J., Phan, V., Beale, P., Peat, J., Clarke, S. (2015). The relationship between nutritional status, inflammatory markers and survival in patients with advanced cancer: a prospective cohort study. Supportive Care in Cancer, 23(2), 385-391. [More Information]
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2014
- Wang, F., Gill, A., Neale, M., Puttaswamy, V., Gananadha, S., Pavlakis, N., Clarke, S., Hugh, T., Samra, J. (2014). Adverse tumor biology associated with mesenterico-portal vein resection influences survival in patients with pancreatic ductal adenocarcinoma. Annals of Surgical Oncology, 21(6), 1937-1947. [More Information]
- Davis, E., Oh, B., Butow, P., Mullan, B., Clarke, S. (2014). Cancer patient disclosure and patient-doctor communication of complementary and alternative medicine use: A systematic review. Forschende Komplementarmedizin, 21(1), 58-59. [More Information]
- Diakos, C., Charles (nee Slaviero), K., McMillan, D., Clarke, S. (2014). Cancer-related inflammation and treatment effectiveness. The Lancet Oncology, 15(11), e493-e503. [More Information]
- Vardy, J., Dhillon, H., Pond, G., Rourke, S., Xu, W., Dodd, A., Renton, C., Park, A., Bekele, T., Ringash, J., Clarke, S., et al (2014). Cognitive function and fatigue after diagnosis of colorectal cancer. Annals of Oncology, 25(12), 2404-2412. [More Information]
- Kao, S., van Zandwijk, N., Clarke, S. (2014). Comment on 'Existing prognostic models, but not neutrophil-to-lymphocyte ratio, are prognostic in malignant mesothelioma'. British Journal of Cancer, 111(12), 2376-2376. [More Information]
- Chik, J., Zhou, J., Moh, E., Christopherson, R., Clarke, S., Molloy, M., Packer, N. (2014). Comprehensive glycomics comparison between colon cancer cell cultures and tumours: Implications for biomarker studies. Journal of Proteomics, 108, 146-162. [More Information]
- Tsoli, M., Schweiger, M., Vanniasinghe, A., Painter, A., Zechner, R., Clarke, S., Robertson, G. (2014). Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation. PloS One, 9(3), e92966- 1--12. [More Information]
- Kim, B., Li, B., Engel, A., Samra, J., Clarke, S., Norton, I., Li, A. (2014). Diagnosis of gastrointestinal bleeding: A practical guide for clinicians. World Journal of Gastrointestinal Pathophysiology, 5(4), 467-478. [More Information]
- Oh, B., Butow, P., Boyle, F., Beale, P., Costa, D., Pavlakis, N., Bell, D., Davis, E., Choi, S., Lee, M., Clarke, S., et al (2014). Effects of Qigong on Quality of Life, Fatigue, Stress, Neuropathy, and Sexual Function in Women with Metastatic Breast Cancer: A Feasibility Study. International Journal of Physical Medicine & Rehabilitation, 2(4), 1-6. [More Information]
- Li, M., Chan, D., Pavlakis, N., Kneebone, A., Bailey, D., Clarke, S. (2014). Enduring complete metabolic response in metastatic adenocarcinoma of the gastro-oesophageal junction. Oxford Medical Case Reports, 2014 (6), 105-106. [More Information]
- Hudson, A., Weir, C., Moon, E., Harvie, R., Klebe, S., Clarke, S., Pavlakis, N., Howell, V. (2014). Establishing a panel of chemo-resistant mesothelioma models for investigating chemo-resistance and identifying new treatments for mesothelioma. Scientific Reports, 4, 1-11. [More Information]
- Linton, A., Pavlakis, N., O’Connell, R., Soeberg, M., Kao, S., Clarke, S., Vardy, J., van Zandwijk, N. (2014). Factors associated with survival in a large series of patients with malignant pleural mesothelioma in New South Wales. British Journal of Cancer, 111(9), 1860-1869. [More Information]
- Hayes, S., Hudson, A., Clarke, S., Molloy, M., Howell, V. (2014). From mice to men: GEMMs as trial patients for new NSCLC therapies. Seminars in Cell & Developmental Biology, 27, 118-127. [More Information]
- Kohonen-Corish, M., Tseung, J., Chan, C., Currey, N., Dent, O., Clarke, S., Bokey, L., Chapuis, P. (2014). KRAS mutations and CDKN2A promoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer. International Journal of Cancer, 134(12), 2820-2828. [More Information]
- Li, B., Pearson, A., Pavlakis, N., Bell, D., Lee, A., Chan, D., Harden, M., Mathur, M., Marshman, D., Brady, P., Clarke, S. (2014). Malignant Cardiac Tamponade from Non-Small Cell Lung Cancer: Case Series from the Era of Molecular Targeted Therapy. Journal of Clinical Medicine, 4(1), 75-84. [More Information]
- Sonpavde, G., Pond, G., Armstrong, A., Clarke, S., Vardy, J., Templeton, A., Wang, S., Paolini, J., Chen, I., Chow-Maneval, E., et al (2014). Prognostic Impact of the Neutrophil-to-Lymphocyte Ratio in Men With Metastatic Castration-Resistant Prostate Cancer. Clinical Genitourinary Cancer, 12(5), 317-324. [More Information]
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2013
- Clarke, S. (2013). A Medical Oncology Approach to Colorectal Cancer. Cancer Nurses Society of Australia Educational Event 2011.
- Hibbert, E., Lambert, T., Carter, J., Learoyd, D., Twigg, S., Clarke, S. (2013). A randomized controlled pilot trial comparing the impact of access to clinical endocrinology video demonstrations with access to usual revision resources on medical student performance of clinical endocrinology skills. BMC Medical Education, 13(1), 1-10. [More Information]
- Clarke, S., Burge, M., Cordwell, C., Gibbs, P., Reece, W., Tebbutt, N. (2013). An Australian translational Study to evaluate the prognostic role of inflammatory markers in patients with metastatic ColorEctal caNcer Treated with bevacizumab (AvastinTM) [ASCENT]. BMC Cancer, 13, 1-7. [More Information]
- Clarke, S. (2013). An Australian Translational Study to Evaluate the Prognostic Role of lnflammatorv Markers in Patients with Metastatic Colorectal Cancer Treated with Bevacizumab (Avastin TM ) [ASCENT]. 2012 COSA 39th Annual Scientific Meeting.
- Toon, C., Walsh, M., Chou, A., Capper, D., Clarkson, A., Sioson, L., Clarke, S., Mead, S., Walters, R., Clendenning, M., Gill, A., et al (2013). BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome. American Journal of Surgical Pathology, 37(10), 1592-1602. [More Information]
- Elens, L., Nieuweboer, A., Clarke, S., Charles (nee Slaviero), K., De Graan, A., Haufroid, V., Mathijssen, R., Van Schaik, R. (2013). CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. Pharmacogenomics, 14(2), 137-149. [More Information]
- Kao, S., Lee, K., Klebe, S., Henderson, D., McCaughan, B., Vardy, J., Clarke, S., van Zandwijk, N. (2013). Excision Repair Cross Complementation Group 1 and Thymidylate Synthase Expression in Patients With Mesothelioma. Clinical Lung Cancer, 14(2), 164-171. [More Information]
- Kacevska, M., Mahns, A., Sharma, R., Clarke, S., Robertson, G., Liddle, C. (2013). Extra-Hepatic Cancer Represses Hepatic Drug Metabolism Via Interleukin (IL)-6 Signalling. Pharmaceutical Research, 30(9), 2270-2278. [More Information]
- Linton, A., Pond, G., Clarke, S., Vardy, J., Galsky, M., Sonpavde, G. (2013). Glasgow Prognostic Score As a Prognostic Factor in Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel-Based Chemotherapy. Clinical Genitourinary Cancer, 11(4), 423-430. [More Information]
- Kao, S., Vardy, J., Harvie, R., Chatfield, M., van Zandwijk, N., Clarke, S., Pavlakis, N. (2013). Health-related quality of life and inflammatory markers in malignant pleural mesothelioma. Supportive Care in Cancer, 21(3), 697-705. [More Information]
- Linton, A., Kao, S., Vardy, J., Clarke, S., van Zandwijk, N., Klebe, S. (2013). Immunohistochemistry in the diagnosis of malignant pleural mesothelioma: Trends in Australia and a literature review. Asia-Pacific Journal of Clinical Oncology, 9(3), 273-279. [More Information]
- Elens, L., Nieuweboer, A., Clarke, S., Charles (nee Slaviero), K., De Graan, A., Haufroid, V., van Gelder, T., Mathijssen, R., Van Schaik, R. (2013). Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin. Pharmacogenetics and Genomics, 23(3), 148-155. [More Information]
- Vardy, J., Dhillon, H., Clarke, S., Olesen, I., Leslie, F., Warby, A., Beith, J., Sullivan, A., Hamilton, A., Beale, P., Rittau, A., McLachlan, A. (2013). Investigation of herb-drug interactions with ginkgo biloba in women receiving hormonal treatment for early breast cancer. SpringerPlus, 2(1), 1-5. [More Information]
- Clarke, S., Karapetis, C., Gibbs, P., Pavlakis, N., Desai, J., Michael, M., Tebbutt, N., Price, T., Tabernero, J. (2013). Overview of biomarkers in metastatic colorectal cancer: Tumour, blood and patient-related factors. Critical Reviews in Oncology / Hematology (online), 85(2), 121-135. [More Information]
- Kao, S., Clarke, S., Vardy, J., Corte, P., Clarke, C., van Zandwijk, N. (2013). Patterns of care for malignant pleural mesothelioma patients compensated by the Dust Diseases Board in New South Wales, Australia. Internal Medicine Journal, 43(4), 402-410. [More Information]
- Jankova, L., Dent, O., Chan, C., Chapuis, P., Clarke, S. (2013). Preoperative neutrophil/lymphocyte ratio predicts overall survival but does not predict recurrence or cancer-specific survival after curative resection of node-positive colorectal cancer. BMC Cancer, 13, 1-13. [More Information]
- Stein, R., Sharpe, L., Bell, M., Boyle, F., Dunn, S., Clarke, S. (2013). Randomized Controlled Trial of a Structured Intervention to Facilitate End-of-Life Decision Making in Patients With Advanced Cancer. Journal of Clinical Oncology, 31(27), 3403-3410. [More Information]
- Hasovits, C., Pavlakis, N., Howell, V., Gill, A., Clarke, S. (2013). Resistance to EGFR targeted antibodies - expansion of clones present from the start of treatment. The more things change, the more they stay the same (Plus ca change, plus ca ne change pas!). Translational Gastrointestinal Cancer, 28(1), 44-46. [More Information]
- Guthrie, G., Charles (nee Slaviero), K., Roxburgh, C., Horgan, P., McMillan, D., Clarke, S. (2013). The systemic inflammation-based neutrophil-lymphocyte ratio: Experience in patients with cancer. Critical Reviews in Oncology / Hematology (online), 88(1), 218-230. [More Information]
- Findlay, M., Bauer, J., Clarke, S., Isenring, E. (2013). Understanding nutritional issues in the older person with cancer. Cancer Forum, 37(3), 234-237.
- Kao, S., van Zandwijk, N., Corte, P., Clarke, C., Clarke, S., Vardy, J. (2013). Use of cancer therapy at the end of life in patients with malignant pleural mesothelioma. Supportive Care in Cancer, 21(7), 1879-1884. [More Information]
- Kao, S., Vardy, J., Chatfield, M., Corte, P., Pavlakis, N., Clarke, C., van Zandwijk, N., Clarke, S. (2013). Validation of Prognostic Factors in Malignant Pleural Mesothelioma: A Retrospective Analysis of Data from Patients Seeking Compensation from the New South Wales Dust Diseases Board. Clinical Lung Cancer, 14(1), 70-77. [More Information]
- de Marinis, F., Clarke, S. (2013). Vitamin supplementation in patients receiving pemetrexed for advanced non-small cell lung cancer. Lung Cancer, 82(3), 511-511. [More Information]
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2012
- Oh, B., Butow, P., Mullan, B., Hale, A., Lee, M., Guo, X., Clarke, S. (2012). A Critical Review of the Effects of Medical Qigong on Quality of Life, Immune Function, and Survival in Cancer Patients. Integrative Cancer Therapies, 11(2), 101-110. [More Information]
- Proctor, M., McMillan, D., Morrison, D., Fletcher, C., Horgan, P., Clarke, S. (2012). A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer. British Journal of Cancer, 107(4), 695-699. [More Information]
- Michael, M., Pavlakis, N., Clingan, P., de Boer, R., Johnston, M., Clarke, S. (2012). A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer. Oncology Reports, 28(3), 763-767. [More Information]
- Tsoli, M., Moore, M., Burg, D., Painter, A., Taylor, R., Lockie, S., Turner, N., Warren, A., Cooney, G., Oldfield, B., Clarke, S., et al (2012). Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice. Cancer Research, 72(17), 4372-4382. [More Information]
- De Gramont, A., Van Cutsem, E., Schmoll, H., Tabernero, J., Clarke, S., Moore, M., Cunningham, D., Cartwright, T., Hecht, J., Rivera, F., et al (2012). Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial. The Lancet Oncology, 13(12), 1225-1233. [More Information]
- Bullen, T., Sharpe, L., Lawsin, C., Patel (nee Chauhan), D., Clarke, S., Bokey, E. (2012). Body image as a predictor of psychopathology in surgical patients with colorectal disease. Journal of Psychosomatic Research, 73(6), 459-463. [More Information]
- Davis, E., Oh, B., Butow, P., Mullan, B., Clarke, S. (2012). Cancer Patient Disclosure and Patient-Doctor Communication of Complementary and Alternative Medicine Use: A Systematic Review. The Oncologist, 17(11), 1475-1481. [More Information]
- Clarke, S. (2012). Comparison of nutritional assessment with a new definition of cachexia in determining outcomes of advanced cancer patients. European Society of Medical Oncology 2012 Congress.
- Shum, A., Mahendradatta, T., Taylor, R., Painter, A., Moore, M., Tsoli, M., Tan, T., Clarke, S., Robertson, G., Polly, P. (2012). Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting. Aging, 4(2), 133-143. [More Information]
- Michael, M., Cullinane, C., Hatzimihalis, A., O'Kane, C., Milner, A., Booth, R., Schlicht, S., Clarke, S., Francis, P. (2012). Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C(14)-erythromycin breath test and the antipyrine clearance test. Cancer Chemotherapy and Pharmacology, 69(1), 125-135. [More Information]
- Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., Lee, M., Rosenthal, D., Larkey, L., Vardy, J. (2012). Effect of Medical Qigong on Cognitive function, Quality of Life and a Biomarker of Inflammation in Cancer Patients: A Randomized Controlled Trial. Supportive Care in Cancer, 20(6), 1235-1242. [More Information]
- Jankova, L., Robertson, G., Chan, C., Tan, K., Kohonen-Corish, M., Fung, C., Clarke, C., Lin, B., Molloy, M., Chapuis, P., Bokey, E., Dent, O., Clarke, S. (2012). Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study. BMC Cancer, 12, 1-9. [More Information]
- Linton, A., van Zandwijk, N., Reid, G., Clarke, S., Cao, C., Kao, S. (2012). Inflammation in malignant mesothelioma - friend or foe? Annals of Cardiothoracic Surgery, 1(4), 516-522. [More Information]
- Clarke, S., McLachlan, A. (2012). Interaction Between Complementary and Alternative Medicines and Conventional Medicines. In Olver, I and Robotin, M (Eds.), Perspectives on Complementary and Alternative Medicines, (pp. 227-259). London: Imperial College Press. [More Information]
- Clarke, S. (2012). Lower Gastrointestinal Cancers Update. 2012 Roche Products Adelaide Post-ASCO Education Meeting.
- Kho, P., Jankova, L., Fung, C., Chan, C., Clarke, C., Lin, B., Robertson, G., Molloy, M., Chapuis, P., Bokey, E., Dent, O., Clarke, S. (2012). Overexpression of protein S100A4 is independently associated with overall survival in stage C colonic cancer but only in cytoplasm at the advancing tumour front. International Journal of Colorectal Disease, 27(11), 1409-1417. [More Information]
- Van Der Wall, H., Elison, B., Frater, C., Bruce, W., Clarke, S. (2012). Pathophysiology of Bone Metastases. In Not known (Eds.), Radionuclide and Hybrid Bone Imaging, (pp. 59-84). TBC. [More Information]
- Hasovits, C., Clarke, S. (2012). Pharmacokinetics and Pharmacodynamics of Intraperitoneal Cancer Chemotherapeutics. Clinical Pharmacokinetics, 51(4), 203-224. [More Information]
- Clarke, S. (2012). Plasma biomarkers of outcome in CRC. Merck Serono Australia Tailored Therapies Meeting- The New Era- Focus on Colorectal Cancer.
- Clarke, S. (2012). Predictive and prognostics factors associated with Mesothelioma and Lung Cancer. Lilly Oncology Australian Scientific Exchange Meeting 2012.
- Clarke, S. (2012). Prognostic Factors in Colorectal Cancer. Roche Haematology & Oncology Targeted Therapies (HOTT) Symposium 2012.
- Randall, S., McKay, M., Pascovici, D., Mahon, K., Horvath, L., Clarke, S., Molloy, M. (2012). Remarkable temporal stability of high-abundance human plasma proteins assessed by targeted mass spectrometry. Proteomics - Clinical Applications, 6(11-12), 626-634. [More Information]
- Chua, W., Horvath, L., Beale, P., Clarke, S. (2012). Reporting clinical trial information: colorectal cancer trials at Sydney Cancer Centre. Internal Medicine Journal, 42(4), 416-421. [More Information]
- Chellappa, K., Jankova, L., Schnabl, J., Pan, S., Brelivet, Y., Fung, C., Chan, C., Dent, O., Clarke, S., Robertson, G., et al (2012). Src tyrosine kinase phosphorylation of nuclear receptor HNF4a correlates with isoform-specific loss of HNF4a in human colon cancer. Proceedings of the National Academy of Sciences of the United States of America, 109(7), 2302-2307. [More Information]
- Chua, W., Clarke, S., Charles (nee Slaviero), K. (2012). Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer. Supportive Care in Cancer, 20(8), 1869-1874. [More Information]
- Clarey, J., Kao, S., Clarke, S., Vardy, J. (2012). The eligibility of advanced non-small-cell lung cancer patients for targeted therapy clinical trials. Annals of Oncology, 23(5), 1229-1233. [More Information]
- Dhillon, H., Van Der Ploeg, H., Bell, M., Boyer, M., Clarke, S., Vardy, J. (2012). The impact of physical activity on fatigue and quality of life in lung cancer patients: A randomised controlled trial protocol. BMC Cancer, 12, 1-9. [More Information]
- Kao, S., Harvie, R., Paturi, F., Taylor, R., Davey, R., Abraham, R., Clarke, S., Marx, G., Cullen, M., Kerestes, Z., Pavlakis, N. (2012). The predictive role of serum VEGF in an advanced malignant mesothelioma patient cohort treated with thalidomide alone or combined with cisplatin/gemcitabine. Lung Cancer, 75(2), 248-254. [More Information]
- Linton, A., Vardy, J., Clarke, S., van Zandwijk, N. (2012). The ticking time-bomb of asbestos: Its insidious role in the development of malignant mesothelioma. Critical Reviews in Oncology / Hematology (online), 84(2), 200-212. [More Information]
- Clarke, S. (2012). Translational research at the Kolling Institute of Medical Research. 5th Annual Hunter Cancer Research Symposium.
- Kho, P., Chapuis, P., Beale, P., Bokey, E., Dent, O., Clarke, S. (2012). Use of adjuvant chemotherapy in stage C (III) rectal cancer: Comparison of data from matched patients in a teaching hospital's clinico-pathological database. Asia-Pacific Journal of Clinical Oncology, 8(4), 346-355. [More Information]
- Clarke, S. (2012). What are a treating team's obligations to ensure access to treatment and compensation for mesothelioma sufferers? 4th Australian Lung Cancer Conference.
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2011
- Kao, S., Yan, T., Lee, K., Burn, J., Henderson, D., Klebe, S., Kennedy, C., Vardy, J., Clarke, S., Van Zandwijk, N., et al (2011). Accuracy of diagnostic biopsy for the histological subtype of malignant pleural mesothelioma. Journal of Thoracic Oncology, 6(3), 602-605. [More Information]
- Phan, V., Tan, C., Rittau, A., Xu, H., McLachlan, A., Clarke, S. (2011). An update on ethnic differences in drug metabolism and toxicity from anti-cancer drugs. Expert Opinion on Drug Metabolism and Toxicology, 7(11), 1395-1410. [More Information]
- Clarke, S. (2011). Bone Metastases. Nuclear Medicine Society NSW Educational Meeting.
- Clarke, S. (2011). Cancer in Northern Sydney. Kolling Institute of Medical Research Public Forum "Our Fight Against Cancer".
- Fung, D., Lo, A., Jankova, L., Clarke, S., Molloy, M., Robertson, G., Wilkins, M. (2011). Classification of Cancer Patients Using Pathway Analysis and Network Clustering. In Gerard Cagney, Andrew Emili (Eds.), Network Biology: Methods and Applications, (pp. 311-336). New York: Humana Press.
- He, X., Clarke, S., McLachlan, A. (2011). Clinical pharmacology of chemotherapy agents in older people with cancer. Current Gerontology and Geriatrics Research, 2011, 628670-1-628670-6. [More Information]
- Chua, W., Kho, P., Moore, M., Charles (nee Slaviero), K., Clarke, S. (2011). Clinical, laboratory and molecular factors predicting chemotherapy efficacy and toxicity in colorectal cancer. Critical Reviews in Oncology/Hematology, 79(3), 224-250. [More Information]
- Tan, K., Jankova, L., Chan, C., Fung, C., Clarke, C., Lin, B., Robertson, G., Molloy, M., Chapuis, P., Bokey, E., Clarke, S., et al (2011). Clinicopathological correlates and prognostic significance of glutathione S-transferase Pi expression in 468 patients after potentially curative resection of node-positive colonic cancer. Histopathology, 59(6), 1057-1070. [More Information]
- Zhou, J., Belov, L., Solomon, M., Chan, C., Clarke, S., Christopherson, R. (2011). Colorectal cancer cell surface protein profiling using an antibody microarray and fluorescence multiplexing. Journal of Visualized Experiments, (55), 1-6. [More Information]
- Kacevska, M., Downes, M., Sharma, R., Evans, R., Clarke, S., Liddle, C., Robertson, G. (2011). Extrahepatic Cancer Suppresses Nuclear Receptor-Regulated Drug Metabolism. Clinical Cancer Research, 17(10), 3170-3180. [More Information]
- Clarke, S., McLachlan, A. (2011). Interaction between complementary and alternative medicine with conventional anti-cancer medicine. Cancer Forum, 35(1), 18-23. [More Information]
- Lee, A., Chick, J., Kolarich, D., Haynes, P., Robertson, G., Tsoli, M., Jankova, L., Clarke, S., Packer, N., Baker, M. (2011). Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumour. Molecular and Cellular Proteomics, 10(9), 1-18. [More Information]
- Kao, S., Klebe, S., Henderson, D., Reid, G., Chatfield, M., Armstrong, N., Yan, T., Vardy, J., Clarke, S., van Zandwijk, N., McCaughan, B. (2011). Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy. Journal of Thoracic Oncology, 6(11), 1923-1929. [More Information]
- Chua, W., Charles (nee Slaviero), K., Baracos, V., Clarke, S. (2011). Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer. British Journal of Cancer, 104(8), 1288-1295. [More Information]
- Backshall, A., Sharma, R., Clarke, S., Keun, H. (2011). Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine. Clinical Cancer Research, 17(9), 3019-3028. [More Information]
- Clarke, S. (2011). Plenary address: Cancer Research at the Universitv of Sydney. Cancer Research Network Postgraduate Symposium 2011.
- Clarke, S. (2011). Predicting outcomes in Lung Cancer. The Second Oncology Forum of Chinese Physicians from China and the US (OFCCU).
- Clarke, S. (2011). Predicting outcomes of cancer treatment. 2011 ARCS Scientific Congress.
- Jankova, L., Chan, C., Fung, C., Song, X., Kwun, S., Cowley, M., Kaplan, W., Dent, O., Bokey, E., Chapuis, P., Robertson, G., Clarke, S., et al (2011). Proteomic comparison of colorectal tumours and non-neoplastic mucosa from paired patient samples using iTRAQ mass spectrometry. Molecular BioSystems, 7(11), 2997-3005. [More Information]
- Mitchell, P., Broad, A., Rosenthal, M., Galettis, P., Abraham, R., Burns, I., Clarke, S., Milner, A., Diiulio, J., Links, M. (2011). Randomized phase 2 sequencing and pharmacokinetic study of gemcitabine and oxaliplatin in advanced non-small cell lung cancer. Asia-Pacific Journal of Clinical Oncology, 7(4), 376-384. [More Information]
- Oh, B., Hu, G., Kao, S., Gebski, V., Walls, R., Truong, L., Beale, P., Clarke, S. (2011). Safety and tolerability of Chinese Herbal Medicine with cancer patients receiving chemotherapy. WebmedCentral, 2(Article ID: WMC001671), 1-11.
- Clarke, S., Yip, S., Brown, C., van Hazel, G., Ransom, D., Goldstein, D., Jeffrey, G., Tebbutt, N., Buck, M., Lowenthal, R., Boland, A., Gebski, V., Simes, R., et al (2011). Single-agent irinotecan or 5-fluorouracil and leucovorin (FOLFIRI) as second-line chemotherapy for advanced colorectal cancer; results of a randomised phase II study (DaVINCI) and meta-analysis. European Journal of Cancer, 47(12), 1826-1836. [More Information]
- Clarke, S. (2011). Successes, challenges and future directions. In Dimitrios H Roukos (Eds.), Advances in Personalized Cancer Management, (pp. 84-95). London: Future Medicine Ltd. [More Information]
- Leighl, N., Shepherd, H., Butow, P., Clarke, S., McJannett, M., Beale, P., Wilcken, N., Moore, M., Chen, E., Goldstein, D., Horvath, L., Tattersall, M., et al (2011). Supporting Treatment Decision Making in Advanced Cancer: A Randomized Trial of a Decision Aid for Patients With Advanced Colorectal Cancer Considering Chemotherapy. Journal of Clinical Oncology, 29(15), 2077-2084. [More Information]
- Sharpe, L., Patel (nee Chauhan), D., Clarke, S. (2011). The relationship between body image disturbance and distress in colorectal cancer patients with and without stomas. Journal of Psychosomatic Research, 70(5), 395-402. [More Information]
- Clarke, S. (2011). Update on Neuroendocrine. Endocrine and Oncology Nurses of Australia Symposium.
- Clarke, S., Chua, W., Moore, M., Kao, S., Phan, V., Tan, C., Charles (nee Slaviero), K., McMillan, D. (2011). Use of inflammatory markers to guide cancer treatment. Clinical Pharmacology & Therapeutics, 90(3), 475-478. [More Information]
- Clarke, S. (2011). Use of the neutrophil lymphocyte ratio to predict outcomes from chemotherapy. Medical Oncology Group of Australia Limited Annual Scientific Meeting 2011, Adelaide, South Australia: Medical Oncology Group of Australia.
- Patel (nee Chauhan), D., Sharpe, L., Thewes, B., Bell, M., Clarke, S. (2011). Using the distress thermometer and hospital anxiety and depression scale to screen for psychosocial morbidity in patients diagnosed with colorectal cancer. Journal of Affective Disorders, 131(1-3), 412-416. [More Information]
- Kao, S., Griggs, K., Lee, K., Armstrong, N., Clarke, S., Vardy, J., van Zandwijk, N., Burn, J., McCaughan, B., Henderson, D., et al (2011). Validation of a minimal panel of antibodies for the diagnosis of malignant pleural mesothelioma. Pathology, 43(4), 313-317. [More Information]
- Kao, S., Lee, K., Armstrong, N., Clarke, S., Vardy, J., van Zandwijk, N., Reid, G., Burn, J., McCaughan, B., Henderson, D., et al (2011). Validation of tissue microarray technology in malignant pleural mesothelioma. Pathology, 43(2), 128-132. [More Information]
- Cassidy, J., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Rittweger, K., Gilberg, F., Saltz, L. (2011). XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results. British Journal of Cancer, 105(1 Spring 2010), 58-64. [More Information]
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2010
- Blinman, P., Duric, V., Nowak, A., Beale, P., Clarke, S., Briscoe, K., Boyce, A., Goldstein, D., Hudson, M., Stockler, M. (2010). Adjuvant chemotherapy for early colon cancer: What survival benefits make it worthwhile? European Journal of Cancer, 46(10), 1800-1807. [More Information]
- Clarke, S., McLachlan, A., Brown, D., Carbonara, S., Kissane, R. (2010). Beyond Conventional Cancer Treatments: The Use of Complementary Therapies During Cancer Treatment: Implications for Clinicians. In Monica Robotin, Ian Olver, Afaf Girgis (Eds.), When Cancer Crosses Disciplines: A Physicians Handbook, (pp. 285-315). London: Imperial College Press. [More Information]
- Chua, W., Clarke, S. (2010). Clinical Trial Information As a Measure of Quality Cancer Care. Journal of Oncology Practice, 6(3), 170-171. [More Information]
- Fung, C., Chan, C., Jankova, L., Dent, O., Robertson, G., Molloy, M., Bokey, E., Chapuis, P., Lin, B., Clarke, S. (2010). Clinicopathological correlates and prognostic significance of maspin expression in 450 patients after potentially curative resection of node-positive colonic cancer. Histopathology, 56(3), 319-330. [More Information]
- Clarke, S. (2010). Evaluating Chemotherapy Toxicity/Antimetabolite Chemotherapy. Medical Oncology Group of Australia Basic Sciences of Oncology Program 2010.
- Chan, C., Jankova, L., Fung, C., Clarke, C., Robertson, G., Chapuis, P., Bokey, E., Lin, B., Dent, O., Clarke, S. (2010). Fascin Expression Predicts Survival After Potentially Curative Resection of Node-positive Colon Cancer. American Journal of Surgical Pathology, 34(5), 656-666. [More Information]
- Kao, S., Pavlakis, N., Harvie, R., Vardy, J., Boyer, M., van Zandwijk, N., Clarke, S. (2010). High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy. Clinical Cancer Research, 16(23), 5805-5813. [More Information]
- Lam, F., Jankova, L., Dent, O., Molloy, M., Kwun, S., Clarke, C., Chapuis, P., Robertson, G., Beale, P., Clarke, S., Bokey, E., Chan, C. (2010). Identification of distinctive protein expression patterns in colorectal adenoma. Proteomics - Clinical Applications, 4(1), 60-70. [More Information]
- Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., Kothe, E., Lam, L., Rosenthal, D. (2010). Impact of Medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial. Annals of Oncology, 21(3), 608-614. [More Information]
- Moore, M., Chua, W., Charles (nee Slaviero), K., Clarke, S. (2010). Inflammation and Cancer: Causes and Consequences. Clinical Pharmacology & Therapeutics, 87(4), 504-508. [More Information]
- Clarke, S. (2010). Interacting with Pharma. 2010 Joint MOGA and Private Cancer Physicians of Australia.
- Kho, P., Chua, W., Moore, M., Clarke, S. (2010). Is it Prime Time for Personalized Medicine in Cancer Treatment? Personalized Medicine, 7(4), 387-397. [More Information]
- Clarke, S. (2010). lndividualisation of Chemotherapy in Colorectal Cancer. Colorectal Cancer - A Multidisciplinary Approach Meeting.
- Kao, S., Reid, G., Bracken, K., Vardy, J., Clarke, S., van Zandwijk, N. (2010). Malignant Mesothelioma. International Medical Journal. [More Information]
- Clarke, S. (2010). Options in Academia. Pfizer Advanced Trainee Education Meeting.
- Kao, S., Butow, P., Bray, V., Clarke, S., Vardy, J. (2010). Patient and oncologist estimates of survival in advanced cancer patients. Psycho-Oncology, 10(2), 213-218. [More Information]
- Oh, B., Butow, P., Mullan, B., Clarke, S., Tattersall, M., Boyer, M., Beale, P., Vardy, J., Pavlakis, N., Larke, L. (2010). Patient-Doctor Communication: Use of Complementary and Alternative Medicine by Adult Patients with Cancer. Journal of the Society for Integrative Oncology, 8(2), 56-64. [More Information]
- Kao, S., Phan, V., Clarke, S. (2010). Predictive Markers for Haematological Toxicity of Pemetrexed. Current Drug Targets, 11(1), 48-57. [More Information]
- Clarke, S. (2010). Predictors of outcomes in colorectal cancer. Ludwig Institute Colon Cancer Symposium.
- Zhou, J., Belov, L., Huang, P., Shin, J., Solomon, M., Chapuis, P., Bokey, E., Chan, C., Clarke, C., Clarke, S., Christopherson, R. (2010). Surface antigen profiling of colorectal cancer using antibody microarrays with fluorescence multiplexing. Journal of Immunological Methods, 355(40210 (1-2)), 40-51. [More Information]
- Matic, M., Carradin, A., Tsoli, M., Clarke, S., Polly, P., Robertson, G. (2010). The alternatively spliced murine pregnane X receptor isoform, mPXRD171-211 exhibits a repressive action. International Journal of Biochemistry and Cell Biology, 42(5), 672-682. [More Information]
- Oh, B., Butow, P., Mullan, B., Beale, P., Pavlakis, N., Rosenthal, D., Clarke, S. (2010). The use and perceived benefits resulting from the use of complementary and alternative medicine by cancer patients in Australia. Asia-Pacific Journal of Clinical Oncology, 6(4), 342-349. [More Information]
- Clarke, S. (2010). Updates in Medical Oncology. 2010 ARCS Australia Annual Scientific Congress.
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2009
- Matic, M., Nakhel, S., Lehnert, A., Polly, P., Clarke, S., Robertson, G. (2009). A novel approach to investigate the subcellular distribution of nuclear receptors in vivo. Nuclear Receptor Signaling, 7, 1-7. [More Information]
- Chapuis, P., Bokey, E., Clarke, S., Beale, P., Dent, O. (2009). Adjuvant chemotherapy for stage C colonic cancer in a multidisciplinary setting. ANZ Journal of Surgery, 79(10), 685-692. [More Information]
- Clarke, S. (2009). Advanced colorectal cancer - where are we going? AstraZeneca Challenges in Gastroenterology Symposium.
- Chua, W., Peters, M., Loneragan, R., Clarke, S. (2009). Cetuximab-Associated Pulmonary Toxicity. Clinical Colorectal Cancer, 8(2), 118-120. [More Information]
- Clarke, S. (2009). Chemotherapy and timing of surgery. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009.
- Vardy, J., Dadasovich, R., Beale, P., Boyer, M., Clarke, S. (2009). Eligibility of patients with advanced non-small cell lung cancer for phase III chemotherapy trials. BMC Cancer, 9, 1-6. [More Information]
- Hong, P., Moore, M., McLachlan, A., Piquette-Miller, M., Xu, H., Clarke, S. (2009). Ethnic differences in drug metabolism and toxicity from chemotherapy. Expert Opinion on Drug Metabolism and Toxicology, 5(3), 243-257. [More Information]
- Sharma, R., Cunningham, D., Smith, P., Robertson, G., Dent, O., Clarke, S. (2009). Inflammatory (B) symptoms are independent predictors of myelosuppression from chemotherapy in Non-Hodgkin Lymphoma (NHL) patients-analysis of data from a British National Lymphoma Investigation phase III trial comparing CHOP to PMitCEBO. BMC Cancer, 9, 153-1-153-10. [More Information]
- Clarke, S. (2009). Interactions with cancer therapies. Clinical Oncological Society of Australia 36th Annual Scientific Meeting: Awareness, Access, Action.
- Clarke, S. (2009). Managing complex/multiple focus disease areas & networks: the cancer experience. National Institute of Complementary Medicine 2009 National Symposium: Supporting health priorities & industry growth.
- Chua, W., Goldstein, D., Lee, C., Dhillon, H., Michael, M., Mitchell, P., Clark, S., Iacopetta, B. (2009). Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer. British Journal of Cancer, 101(6), 998-1004. [More Information]
- Sobrero, A., Ackland, S., Clarke, S., Perez-Carrion, R., Chiara, S., Gapski, J., Mainwaring, P., Langer, B., Young, S. (2009). Phase IV Study of Bevacizumab in Combination with Infusional Fluorouracil, Leucovorin and Irinotecan (FOLFIRI) in First-Line Metastatic Colorectal Cancer. Oncology, 77(2), 113-119. [More Information]
- Clarke, S. (2009). Plasma proteomic predictors of response and toxicitv in colorectal cancer patients receiving chemotherapy. 2nd Sino-Australian Symposium, N/A: N/A.
- Chua, W., Moore, M., Charles (nee Slaviero), K., Clarke, S. (2009). Predictive biomarkers of clinical response to targeted antibodies in colorectal cancer. Current Opinion in Molecular Therapeutics, 11(6), 611-622. [More Information]
- Clarke, S. (2009). Systemic therapy for Malignant Mesothelioma: An Overview. ANZAC Research Institute’s 8th Annual Symposium.
- Chua, W., Moore, M., Beale, P., Clarke, S. (2009). Third-line Treatment Options for Metastatic Colorectal Cancer. Asia Pacific Journal of Oncology and Hematology, 1(1), 27-35.
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2008
- Van Cutsem, E., Verslype, C., Beale, P., Clarke, S., Bugat, R., Rakhit, A., Fettner, S., Brennscheidt, U., Feyereislova, A., Delord, J. (2008). A phase lb dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients. Annals of Oncology, 19(2), 332-339. [More Information]
- Saltz, L., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2008). Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. Journal of Clinical Oncology, 26(12), 2013-2019. [More Information]
- Read, J., Clarke, S. (2008). Clinical Nutrition. In E. Bruera, I. Higginson, C. Ripamonti, C. von Gunten (Eds.), Palliative Medicine, (pp. 595-601). United Kingdom: Hodder Arnold. [More Information]
- Clarke, S. (2008). DaVINCI Trial Update and Issues in 2nd line chemotherapy. 10th Annual Scientific Meeting of Australasian Gastro-Intestinal Trials Group.
- Clarke, S. (2008). Differences in Chemotherapy. 1st Sino-Australian Symposium.
- Sharma, R., Kacevska, M., London, R., Clarke, S., Liddle, C., Robertson, G. (2008). Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies. British Journal of Cancer, 98(1), 91-97. [More Information]
- Robertson, G., Liddle, C., Clarke, S. (2008). Inflammation and Altered Drug Clearance in Cancer: Transcriptional Repression of a Human CYP3A4 Transgene in Tumor-bearing Mice. Pharmacology and Therapeutics, 83(6), 894-897. [More Information]
- Clarke, S. (2008). Inflammation and cancer drug metabolism. Sydney Cancer Conference 2008 (SCC2008), Sydney: University of Sydney.
- Kacevska, M., Robertson, G., Clarke, S., Liddle, C. (2008). Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing. Expert Opinion on Drug Metabolism and Toxicology, 4(2), 137-149. [More Information]
- Clarke, S. (2008). Inflammation, drug metabolism and chemotherapy toxicity. Hunter Medical Research Institute Conference on Translational Cancer Research.
- Clarke, S. (2008). Inflammatory Response: An unrecognized source of variability in PK/PD of cancer chemotherapy. ASCPT 2008 Annual Meeting.
- Clarke, S. (2008). Infusion vs bolus chemotherapy for colon cancer/Stage II Colon Cancer: Is adjuvant chemotherapy necessary? National Cancer Control Network 1st Asian Scientific Meeting.
- Oh, B., Butow, P., Mullan, B., Clarke, S. (2008). Medical Qigong for cancer patients: Pilot study of impact on quality of life, side effects of treatment and inflammation. American Journal of Chinese Medicine, 36(3), 459-472. [More Information]
- Clarke, S. (2008). New developments in the practice of lung cancer. The Oncology Forum of Chinese Physicians from China and the US (OFCCU).
- Harrison, J., Solomon, M., Young, J., Meagher, A., Butow, P., Salkeld, G., Hruby, G., Clarke, S. (2008). Patient and physician preferences for surgical and adjuvant treatment options for rectal cancer. JAMA (formerly Archives Of Surgery), 143(4), 389-394. [More Information]
- Haller, D., Cassidy, J., Clarke, S., Cunningham, D., Hoff, P., Rothenberg, M., Saltz, L., Allegra, C., et al (2008). Potential regional differences for the tolerability profiles of fluoropyrimidines. Journal of Clinical Oncology, 26(13), 2118-2123. [More Information]
- Clarke, S. (2008). Predicting toxicity from chemotherapy. The Australian Health & Medical Research Congress 2008.
- Cassidy, J., Clarke, S., Diaz-Rubio, E., Scheithauer, W., Figer, A., Wong, R., Koski, S., Lichinitser, M., Yang, T., Rivera, F., et al (2008). Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. Journal of Clinical Oncology, 26(12), 2006-2012. [More Information]
- Morgan, E., Goralski, K., Piquette-Miller, M., Renton, K., Robertson, G., Chaluvadi, M., Charles, K., Clarke, S., Kacevska, M., Liddle, C., et al (2008). Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer. Drug Metabolism and Disposition, 36(2), 205-216. [More Information]
- Chua, W., Beale, P., Clarke, S., Leung, M. (2008). Retrospective review of mitomycin C use as third-line chemotherapy in metastatic colorectal cancer. Asia-Pacific Journal of Clinical Oncology, 4(3), 132-136. [More Information]
- Zalcberg, J., Rosen, L., Abdi, E., Davis, I., Gutheil, J., Schnell, F., Cesano, A., Gayko, U., Chen, M., Clarke, S. (2008). Role of Palifermin in Fluorouracil-Based Therapy for Metastatic Colorectal Cancer. Journal of Clinical Oncology, 26(8), 1386-1387. [More Information]
- Sharma, R., Zucknick, M., London, R., Kacevska, M., Liddle, C., Clarke, S. (2008). Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer. Clinical Colorectal Cancer, 7(5), 331-337. [More Information]
- Sharma, R., Hoskins, J., Rivory, L., Zucknick, M., London, R., Liddle, C., Clarke, S. (2008). Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients. Clinical Cancer Research, 14(3), 817-825. [More Information]
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2007
- Yeo, W., Boyer, M., Chung, H., Ong, S., Lim, R., Zee, B., Ma, B., Lam, K., Mo, F., Ng, E., Clarke, S., Beale, P., et al (2007). Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG). Cancer Chemotherapy and Pharmacology, 59(3), 295-300. [More Information]
- Clarke, S., Goldstein, D., Mitchell, P., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S. (2007). Modification of Leucovorin Dose Within a Simplified FOLFOX Regimen Improves Tolerability Without Compromising Efficacy. Clinical Colorectal Cancer, 6(8), 578-582. [More Information]
- Chuah, B., Lim, R., Boyer, M., Ong, A., Wong, S., Kong, H., Millward, M., Clarke, S., Goh, B. (2007). Multi-centre phase II trial of Thalidomide in the treatment of unresectable hepatocellular carcinoma. Acta Oncologica, 46(2), 234-238. [More Information]
- Li, K., Rivory, L., Clarke, S. (2007). Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules. British Journal of Cancer, 97(8), 1071-1076. [More Information]
- Harrison, J., Solomon, M., Young, J., Meagher, A., Hruby, G., Salkeld, G., Clarke, S. (2007). Surgical and oncology trials for rectal cancer: Who will participate? Surgery, 142(1), 94-101. [More Information]
- McKay, M., Sherman, J., Laver, M., Baker, M., Clarke, S., Molloy, M. (2007). The development of multiple reaction monitoring assays for liver-derived plasma proteins. Proteomics - Clinical Applications, 1(12), 1570-1581. [More Information]
- Leighl, N., Shepherd, H., Butow, P., Clarke, S., McJannett, M., Beale, P., Wilcken, N., Moore, M., Chen, E., Tattersall, M., Goldstein, D. (2007). When the goal is not cure: A randomized trial of a patient decision aid in advanced colorectal cancer. Journal of Clinical Oncology, 25(18S), 6509.
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2006
- Sharma, R., Rivory, L., Beale, P., Ong, S., Horvath, L., Clarke, S. (2006). A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer. British Journal of Cancer, 94(7), 964-968. [More Information]
- Tobin, P., Beale, P., Noney, L., Liddell, S., Rivory, L., Clarke, S. (2006). A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer. Cancer Chemotherapy and Pharmacology, 57(3), 309-316. [More Information]
- Mitchell, P., Goldstein, D., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S., Thomson, J., Clarke, S. (2006). Addition of gabapentin to a modified FOLFOX regimen does not reduce oxaliplatin-induced neurotoxicity. Clinical Colorectal Cancer, 6(2), 146-151. [More Information]
- Nordman, I., Iyer, S., Joshua, A., Clarke, S. (2006). Advances in the adjuvant treatment of colorectal cancer. ANZ Journal of Surgery, 76(5), 373-380. [More Information]
- Read, J., Choy, S., Beale, P., Clarke, S. (2006). An evaluation of the prevalence of malnutrition in cancer patients attending the outpatient oncology clinic. Asia-Pacific Journal of Clinical Oncology, 2(2), 80-86. [More Information]
- Clarke, S., Sharma, R. (2006). Angiogenesis inhibitors in cancer - mechanisms of action. Australian Prescriber, 29(1), 9-12.
- Stockler, M., Tattersall, M., Boyer, M., Clarke, S., Beale, P., Simes, R. (2006). Disarming the guarded prognosis: predicting survival in newly referred patients with incurable cancer. British Journal of Cancer, 94(2), 208-212. [More Information]
- Sobrero, A., Ackland, S., Perez-Carrion, R., Chiara, S., Clarke, S., Giron, C., Langer, B., Zurlo, A., Young, S. (2006). Efficacy and safety of bevacizumab in combination with irinotecan and infusional 5-FU as first-line treatment for patients with metastatic colorectal cancer. 2006 American Society of Clinical Oncology (ASCO) Annual Meeting, United States: American Society of Clinical Oncology.
- Read, J., Choy, S., Beale, P., Clarke, S. (2006). Evaluation of nutritional and inflammatory status of advanced colorectal cancer patients and its correlation with survival. Nutrition and Cancer, 55(1), 78-85. [More Information]
- Read, J., Beale, P., Volker, D., Smith, N., Childs, A., Clarke, S. (2006). Nutrition intervention using an eicosapentaenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: a phase II trial. Supportive Care in Cancer, 15(3), 301-307. [More Information]
- Rosen, L., Abdi, E., Davis, I., Gutheil, J., Schnell, F., Zalcberg, J., Cesano, A., Gayko, U., Chen, M., Clarke, S. (2006). Palifermin Reduces the Incidence of Oral Mucositis in Patients With Metastatic Colorectal Cancer Treated With Fluorouracil-Based Chemotherapy. Journal of Clinical Oncology, 24, 5194-5200. [More Information]
- Aggarwal, G., Glare, P., Clarke, S., Chapuis, P. (2006). Palliative and shared care concepts in patients with advanced colorectal cancer. ANZ Journal of Surgery, 76(3), 175-180. [More Information]
- Charles (nee Slaviero), K., Rivory, L., Stockler, M., Beale, P., Beith, J., Boyer, M., Clarke, S. (2006). Predicting the toxicity of weekly docetaxel in advanced cancer. Clinical Pharmacokinetics, 45(6), 611-622. [More Information]
- Michael, M., Goldstein, D., Clarke, S., Milner, A., Beale, P., Friedlander, M., Mitchell, P. (2006). Prognostic Factors Predictive of Response and Survival to a Modified FOLFOX Regimen: Importance of an Increased Neutrophil Count. Clinical Colorectal Cancer, 6(4), 297-304. [More Information]
- Michael, M., Thompson, M., Hicks, R., Mitchell, P., Ellis, A., Milner, A., Di Iulio, J., Scott, A., Gurtler, V., Clarke, S., Zalcberg, J., et al (2006). Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination. Journal of Clinical Oncology, 24(26), 4228-4235. [More Information]
- Li, K., Rivory, L., Clarke, S. (2006). Solid-phase extraction (SPE) techniques for sample preparation in clinical and pharmaceutical analysis: A brief overview. Current Pharmaceutical Analysis, 2(2), 95-102. [More Information]
- Tobin, P., Clarke, S., Seale, J., Lee, S., Solomon, M., Aulds, S., Crawford, M., Gallagher, J., Eyers, T., Rivory, L. (2006). The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours. British Journal of Clinical Pharmacology, 62(1), 122-129. [More Information]
- Ackland, S., Clarke, S., Beale, P., Peters, G. (2006). Thymidylate synthase inhibitors. Update on Cancer Therapeutics, 1(4), 403-427. [More Information]
- Haller, D., Cassidy, J., Clarke, S., Cunningham, D., Van Cutsem, E., Hoff, P., Rothenberg, M., Saltz, L., Schmoll, H., Twelves, C. (2006). Tolerability of fluoropyrimidines appears to differ by region. 2006 ASCO Annual Meeting, United Kingdom: Oxford University Press.
- Charles (nee Slaviero), K., Rivory, L., Brown, S., Liddle, C., Clarke, S., Robertson, G. (2006). Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer. Clinical Cancer Research, 12(24), 7492-7497. [More Information]
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2005
- Clarke, S., Boyer, M., Millward, M., Underhill, C., Moylan, E., Yip, D., White, S., Childs, A., Beale, P., Latz, J., et al (2005). A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer. Lung Cancer, 49(3), 401-412. [More Information]
- Goldstein, D., Mitchell, P., Michael, M., Beale, P., Friedlander, M., Zalcberg, J., White, S., Clarke, S. (2005). Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients. British Journal of Cancer, 92(5), 832-837. [More Information]
- Sharpe, L., Butow, P., Smith, C., McConnell, D., Clarke, S. (2005). Changes in quality of life in patients with advanced cancer - Evidence of response shift and response restriction. Journal of Psychosomatic Research, 58(6), 497-504. [More Information]
- Vardy, J., Clarke, S. (2005). Ewing''s sarcoma of the rectum: Are four cycles of chemotherapy enough? Reply. Journal of Clinical Oncology, 23(24), 5850-5850.
- Sharma, R., Boyer, M., Clarke, S., Millward, M. (2005). Gefitinib in advanced non-small cell lung cancer. Internal Medicine Journal, 35(2), 77-82. [More Information]
- Joshua, A., Cotroneo, A., Clarke, S. (2005). Humor and oncology. Journal of Clinical Oncology, 23(3), 645-648. [More Information]
- Read, J., Beale, P., Horvath, L., Volker, D., Childs, A., Smith, N., Clarke, S. (2005). Impact of fish-oil supplement on nutritional parameters, inflammation and chemotherapy induced toxicity in colorectal cancer (CRC) patients receiving FOLFIRI - A pilot study. Journal of Clinical Oncology, 23(16S (supplement)), Abstract 8243 S789-S789.
- Sharma, R., Tobin, P., Clarke, S. (2005). Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea. The Lancet Oncology, 6(2), 93-102. [More Information]
- Read, J., Crockett, N., Volker, D., MacLennan, P., Choy, S., Beale, P., Clarke, S. (2005). Nutritional assessment in cancer: comparing the Mini-Nutritional Assessment (MNA) with the scored Patient-Generated Subjective Global Assessment (PGSGA). Nutrition and Cancer, 53(1), 51-56. [More Information]
- Li, K., Rivory, L., Clarke, S. (2005). Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 820(1), 121-130. [More Information]
- Joshua, A., Adams, D., McKenzie, P., Solomon, M., Clarke, S. (2005). Small blue cell tumors of the rectum. Case 2. Small-cell carcinoma of the rectum. Journal of Clinical Oncology, 23(4), 912-3. [More Information]
- Sharma, R., McLeod, D., Clarke, S. (2005). Small blue cell tumors of the rectum. Case 3. Atypical carcinoid of the rectum. Journal of Clinical Oncology, 23(4), 914-5. [More Information]
- Vardy, J., Joshua, A., Clarke, S., Yarrow, P., Lin, B. (2005). Small blue cell tumors of the rectum: CASE 1. Ewing's sarcoma of the rectum. Journal of Clinical Oncology, 23(4), 910-912. [More Information]
- Joshua, A., Boyer, M., Subramanian, R., Clarke, S. (2005). Smoking reduction does work: resulting alterations in the incidence and histological subtypes of lung cancer in New South Wales in the last 20 years. Respirology, 10(2), 233-238. [More Information]
- Tobin, P., Seale, P., Lee, S., Solomon, M., Fields, S., Rivory, L., Clarke, S. (2005). The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours. 2005 American Society of Clinical Oncology (ASCO) Annual Meeting, United States: American Society of Clinical Oncology.
- Sharpe, L., Butow, P., Smith, C., McConnell, D., Clarke, S. (2005). The relationship between available support, unmet needs and caregiver burden in patients with advanced cancer and their carers. Psycho-Oncology, 14(2), 102-114. [More Information]
- Clarke, S., Boyer, M., Stockler, M., Venkatawaran, R., Nordman, I., Joshua, A. (2005). Weekly docetaxel as second line treatment after mitoxantrone for androgen-independent prostate cancer (AIPC). 2005 ASCO Annual Meeting, NY, USA: American Society of Clinical Oncology.
- Joshua, A., Nordman, I., Venkataswaran, R., Clarke, S., Stockler, M., Boyer, M. (2005). Weekly docetaxel as second line treatment after mitozantrone for androgen-independent prostate cancer. Internal Medicine Journal, 35(8), 468-472. [More Information]
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2004
- Baker, S., Van Schaik, R., Rivory, L., Ten Tije, A., Dinh, K., Graveland, W., Schenk, P., Charles, J., Clarke, S., Carducci, M., Sparreboom, A., et al (2004). Factors Affecting Cytochrome P-450 3A Activity In Cancer Patients. Clinical Cancer Research, 10(12), 8341-8350. [More Information]
- Tobin, P., Rivory, L., Clarke, S. (2004). Inhibition of acetylcholinesterase in patients receiving irinotecan (camptothecin-11). Pharmacology and Therapeutics, 76(5), 505-506. [More Information]
- Vardy, J., Engelhardt, K., Cox, K., Jacquet, J., McDade, A., Boyer, M., Beale, P., Clarke, S., Stockler, M., Loneragan, R., Waugh, R., Clarke, S. (2004). Long-Term Outcome Of Radiological-Guided Insertion Of Implanted Central Venous Access Port Devices (Cvapd) For The Delivery Of Chemotherapy In Cancer Patients: Institutional Experience And Review Of The Literature. British Journal of Cancer, 91(6), 1045-1049. [More Information]
- Blair, E., Rivory, L., Clarke, S., McLachlan, A. (2004). Population Pharmacokinetics Of Raltitrexed In Patients With Advanced Solid Tumours. British Journal of Clinical Pharmacology, 57(4), 416-426. [More Information]
- Charles (nee Slaviero), K., Clarke, S., McLachlan, A., Blair, E., Rivory, L. (2004). Population Pharmacokinetics Of Weekly Docetaxel In Patients With Advanced Cancer. British Journal of Clinical Pharmacology, 57(1), 44-53. [More Information]
- Zhang, M., Boyer, M., Rivory, L., Hong, A., Clarke, S., Stevens, G., Fife, K. (2004). Radiosensitization Of Vinorelbine And Gemcitabine In Nci-H460 Non-Small-Cell Lung Cancer Cells. International Journal of Radiation: Oncology - Biology - Physics, 58(2), 353-360. [More Information]
- Featherstone, C., Clarke, S., Jackson, M., Shannon, K., McNeil, E., Tin, M., Clifford, A., O'Brien, C. (2004). Treatment Of Advanced Cancer Of The Larynx And Hypopharynx With Chemoradiation. ANZ Journal of Surgery, 74(7), 554-558. [More Information]
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2003
- Smit, E., Mattson, K., von Pawel, J., Manegold, C., Clarke, S., Postmus, P. (2003). ALIMTA® (pemetrexed disodium) as second-line treatment of non-small-cell lung cancer: a phase II study. Annals of Oncology, 14(3), 455-460. [More Information]
- Clarke, S. (2003). An 85-year old woman with metastatic liver disease: clinical case review. Medicine Today, 4(1), 72-73.
- Charles (nee Slaviero), K., Read, J., Clarke, S., Rivory, L. (2003). Baseline Nutritional Assessment in Advanced Cancer Patients Receiving Palliative Chemotherapy. Nutrition and Cancer, 46(2), 148-157. [More Information]
- Tattersall, M., Clarke, S. (2003). Developments in drug delivery: implications for cancer care. Current Opinion in Oncology, 15(4), 293-299. [More Information]
- Van Der Wall, H., Clarke, S., Murray, I. (2003). Evaluation of primary bone tumours. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 623-639). Edinburgh: Churchill Livingstone.
- Charles (nee Slaviero), K., Clarke, S., Rivory, L. (2003). Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy. The Lancet Oncology, 4(4), 224-232. [More Information]
- Saw, R., Morgan, M., Koorey, D., Painter, D., Findlay, M., Stevens, G., Clarke, S., Chapuis, P., Solomon, M. (2003). P53, deleted in colorectal cancer gene, and thymidylate synthase as predictors of histopathologic response and survival in low, locally advanced rectal cancer treated with preoperative adjuvant therapy. Diseases of the Colon and Rectum, 46(2), 192-202. [More Information]
- Li, K., Clarke, S., Rivory, L. (2003). Quantitation of plasma thymidine by high-performance liquid chromatography - atmospheric pressure chemical ionization mass spectromentry and its application to pharmocodynamic studies in cancer patients. Analytica Chimica Acta, 486(1), 51-61. [More Information]
- Van Der Wall, H., Clarke, S., Murray, I. (2003). The evaluation of malignancy: metastatic bone disease. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 641-655). Edinburgh: Churchill Livingstone.
- Tobin, P., Dodds, H., Clarke, S., Schnitzler, M., Rivory, L. (2003). The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours. Oncology Reports, 10(6), 1977-1979.
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2002
- Aristides, M., Chen, J., Schulz, M., Williamson, E., Clarke, S., Grant, K. (2002). Conjoint analysis of a new chemotherapy: willingness to pay and preference for the features of raltitrexed versus standard therapy in advanced colorectal cancer. PharmacoEconomics, 20(11), 775-784. [More Information]
- Cunningham, D., Zalcberg, J., Maroun, J., James, R., Clarke, S., Maughan, T., Vincent, M., Schulz, J., Gonzalez Baron, M., Facchini, T. (2002). Efficacy, tolerability and management of raltitrexed (Tomudex TM) monotherapy in patients with advanced colorectal cancer: a review of phase II/III trials. European Journal of Cancer, 38(4), 478-486. [More Information]
- Rivory, L., Charles (nee Slaviero), K., Clarke, S. (2002). Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. British Journal of Cancer, 87(3), 277-280. [More Information]
- Vardy, J., Wong, E., Izard, M., Clifford, A., Clarke, S. (2002). Life-threatening anaphylactoid reaction to amifostine used with concurrent chemoradiotherapy for nasopharyngeal cancer in a patient with dermatomyositis: a case report with literature review. Anti-Cancer Drugs, 13(3), 327-330. [More Information]
- Clarke, S. (2002). New treatments for advanced and metastatic colorectal cancer - clinical applications. Australian Prescriber, 25(5), 111-113. [More Information]
- Rischin, D., Ackland, S., Smith, J., Garg, M., Clarke, S., Millward, M., Toner, G., Zalcberg, J. (2002). Phase I and pharmacokinetic study of docetaxel in combination with epirubicin and cyclophosphamide in advanced cancer: dose escalation possible with granulocyte colony-stimulating factor, but not with prophylactic antibodies. Annals of Oncology, 13(11), 1810-1818. [More Information]
- Clarke, S., Abratt, R., Goedhals, L., Boyer, M., Millward, M., Ackland, S. (2002). Phase II trial of pemetrexed disodium (ALIMTA[R], LY231514) in chemotherapy-naive patients with advanced non-small-cell lung cancer. Annals of Oncology, 13(5), 737-741. [More Information]
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2001
- Rivory, L., Clarke, S., Boyer, M., Bishop, J. (2001). Highly sensitive analysis of the antifolate pemetrexed sodium, a new cancer agent, in human plasma and urine by high-performance liquid chromatography. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 765, 135-140.
- Rivory, L., Charles (nee Slaviero), K., Hoskins, J., Clarke, S. (2001). The erythromycin breath test for the prediction of drug clearance. Clinical Pharmacokinetics, 40, 151-158. [More Information]
- Clarke, S., Bishop, J., Dodds, H., Rivory, L., Ong,, S. (2001). Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction. Anti-Cancer Drugs, 12, 619-625. [More Information]
2000
- Clarke, S., Beale, P., Rivory, L. (2000). Clinical and preclinical pharmacokinetics of raltitrexed. Clinical Pharmacokinetics, 39, 429-443. [More Information]
Selected Grants
2019
- Identification of plasma extracellular vesicles signatures in lung cancer patients with brain metastases versus those without, Grau G, Kao S, Hosseini Beheshti E, Clarke S, University of Sydney/Sydney Catalyst
- Oxtox: Can Oxaliplatin dose reduction and neurotoxicity be reduced with ibudilast in people with metastatic colorectal cancer - a phase II randomised study, Vardy J, Dhillon H, Stockler M, Clarke S, Australasian Gastro-Intestinal Trials Group/Research Support
2017
- Identification of diagnostic protein biomarkers for less invasive screening of lung cancer, Hayes S, Howell V, Pavlakis N, Molloy M, Clarke S, Tour de Cure Ltd/Scott Canner Young Research Grant
2016
- From mice to men: biomarker-driven classification of pancreatic cancer to define the gemcitabine/ nab-paclitaxel-responsive molecular subtype, Pajic M, Timpson P, Gill A, Clarke S, Burgess A, Samra J, Cancer Australia/Priority Driven Collaborative Cancer Research Scheme
2015
- Cognitive ageing in cancer populations: a cohort study extension in colorectal cancer survivors, McLachlan A, Dhillon H, Vardy J, Waite L, Lagopoulos J, Mackenzie L, Johnston I, Clarke S, Cysique L, DVC Research/SPARC Implementation - Cancer
- The Sydney 1000 Cancer Project – Stage 1 Gastrointestinal Cancers Immunophenotyping Study, Charles (nee Slaviero) K, Clarke S, Diakos C, Pavlakis N, Engel A, Samra J, Gill A, Kneebone A, Fazekas de St Groth B, Hart D, Smith A, Byrne S, McGuire H, Vafaee F, King M, DVC Research/SPARC Implementation - Cancer
2014
- Therapeutic targeting of cell cycle checkpoint aberrations in pancreatic cancer: personalised medicine in action, Pajic M, Timpson P, Gill A, Clarke S, Burgess A, National Health and Medical Research Council (NHMRC)/Project Grants
- Northern Translational Cancer Research Centre NTCRC Sydney Vital, Bailey D, Engel A, Boyle F, Clarke S, Gill A, Marsh D, Nguyen S, Molloy M, Cancer Institute NSW/Translational Cancer Research Centre
2012
- Towards Personalizing Chemotherapeutic Treatment for Cancer - Investigating Inter-Ethnic Differences in Genetic Susceptibility to Anti-Cancer Drug Toxicity, Howell V, Clarke S, Rebecca L Cooper Medical Research Foundation/Equipment Grant
- Advance care planning in incurable cancer patients with disease progression on first line chemotherapy: a randomised trial., Tattersall M, Silvester W, Clayton J, Detering K, Hall J, Butow P, Kiely B, Cebon J, Clarke S, Bell M, National Health and Medical Research Council (NHMRC)/Project Grants
- Advance care planning in incurable cancer patients with disease progression on first line chemotherapy: a randomised trial, Clarke S, National Health and Medical Research Council (NHMRC)/Project Grants
- The impact of physical activity on fatigue and quality of life in lung cancer patients, Vardy J, Clarke S, Dhillon H, Boyer M, Slater and Gordon Asbestos Research Fund/Vojakovic Fellowship
- MALDI MS Imaging for Cancer Biomarker Discovery in the Northern Translational Cancer Research Unit, Clarke S, Cancer Institute NSW/Research Infrastructure Grant FPRx1906 SCHx26326
- Ginkgo biloba preserves cognitive function in women treated with adjuvant chemotherapy for early breast cancer: a double-blind, placebo-controlled, randomised phase III trial, Vardy J, Tattersall M, Dhillon H, Bell M, Cysique L, Boyle F, Clarke S, Cancer Australia/Priority Driven Collaborative Cancer Research Scheme
2011
- Determining the tumour suppressor function of the MCC gene and its significance to treatment outcomes in colorectal cancer, Clarke S, National Health and Medical Research Council (NHMRC)/Project Grants
- Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer, Baxter R, Halliday G, Marsh D, Gill A, Clarke S, Smith R, Little C, Jackson C, O'Neill C, Murphy C, Sharland A, Chadban S, Mason R, Assinder S, Verdurand M, Richardson D, Machaalani R, Hambly B, Chan-Ling T, Dos Remedios C, Holsinger D, Lay P, National Health and Medical Research Council (NHMRC)/Equipment Grant
- Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer, with associated Biomarker Identification and MALDI-Imaging Solutions, Clarke S, University of Sydney/Cancer Research Fund
- Ginkgo biloba preserves cognitive function in women treated with adjuvant chemotherapy for early breast cancer: a double-blind, placebo-controlled, randomised phase III trial, Clarke S, Cancer Australia/Research
- Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer, with associated Biomarker Identification and MALDI-Imaging solutions, Clarke S, University of Sydney/Cancer Research Fund Research Infrastructure Grant
- Northern Translational Cancer Research Unit, Engel A, Clarke S, Cancer Institute NSW/Translational Health Services Research Grant
- Northern Translational Cancer Research Unit, Clarke S, Cancer Institute NSW/Translational Cancer Research Unit Establishment Grant FPRx1906 SCHx26323
2010
- Genotype Guided Cancer Therapy (Genomic Theranostics), Clarke S, Cancer Council NSW/Strategic Research Partnership (STREP) Grants
- Identifying New Plasma Markers In Mesothelioma, Clarke S, Cancer Institute NSW/Research Innovation Grant FPRx1906 SCHx26322
- GenomeLab GeXP Genetic Analysis System for the Multi-Disciplinary Sydney Cancer Gene Expression Facility, Richardson D, Halliday G, Scolyer R, Clarke S, Lee C, Reichardt J, Clarke C, Murray M, Boyer M, Kefford R, Cancer Institute NSW/Equipment Grant
2009
- Building capacity in pharmacogenomics across NSW: PRIMe (Pharmacogenomic Research for Individualised Medicine), Clarke S, Cancer Council NSW/Research Program Grant in Cancer Pharmacogenomics
- Genomelab GeXP Genetic Analysis System for the Multi-Disciplinary Sydney Cancer Gene Expression Facility, Clarke S, Cancer Institute NSW/Research Equipment Grant FPRx1906 SCHx26312
- A proteomic approach to identify predictive biomarkers of molecular targeted drugs, Charles (nee Slaviero) K, Clarke S, Cancer Institute NSW/Research Innovation Grants
- The Lunar PIXImus II DEXA Scanner, Zhou H, Seibel M, Handelsman D, Le Couteur D, Nicholson G, Clarke S, Robertson G, van Zandwijk N, Freedman B, Kennerson M, Allan C, Walters K, Cogger V, Blair I, Reid G, Simanainen U, National Health and Medical Research Council (NHMRC)/Equipment Grant
- Improving the use of chemotherapy by targeting the inflammatory response, Clarke S, Robertson G, Piquette-Miller M, McLachlan A, Baker M, Katsifis A, National Health and Medical Research Council (NHMRC)/Project Grants
- A mass spectrometer for cancer biomarker research, Clarke S, Cancer Institute NSW/Research Equipment Grant FPRx1906 SCHx26312
- Clinical Studies of the Efficacy and Tolerability of Systemically Administered Complementary and Alternative Medicine (CAM) in Conjunction with Standary Therapy in Cancer Patients, Vardy J, Clarke S, National Center for Complementary Medicine/Integrated Care Research Program
- China: NSW Cancer Genesis, Spread and Treatment Proteomic Discovery Program, Baker M, Wilkins M, Hancock W, Malloy M, Clarke S, Wilkins M, Packer N, He F, Office for Science and Medical Research (NSW)/China - NSW Collaborative Research Grant Program
2008
- -80°C Scientific freezer for storage of blood samples, Clarke S, The Sydney Cancer Centre Foundation (Chris OBrien Lifehouse)./Capital Works & Equipment Grant
- Individualised treatment for cancer patients: Impact of tumour-derived cytokines on drug clearance pathways in cancer, Clarke S, DVC Research/Bridging Support Grant
- The impact of physical activity on quality of life in thoracic cancer patients, Clarke S, Lance Armstrong Foundation/Young Investigator Grant
- Multi-photon microscope for intravital imaging, Weninger W, Vadas M, Hogg P, Norris M, Fazekas de St Groth B, Haass N, Clarke S, Halliday G, Rasko J, Holst J, McCaughan G, Allen J, Gamble J, Dong Q, Byrne S, Richardson D, Cancer Institute NSW/Equipment Grant
- Clinical studies of the efficacy & tolerability of systemically administered Complementary & Alternative Medicine (CAM) in conjunction with standard therapy in cancer patients, Clarke S, National Institute of Complementary Medicine/Research Program Developmental Grant
- China:NSW Cancer Genesis, Spread, & Treatment Proteomic Discovery Program, Clarke S, NSW Office for Science and Medical Research/The China-NSW Collaborative Research Program
- Inverted Multiphoton Intravital Microscope, Gorrell M, Weninger W, Halliday G, Jones C, Fazekas de St Groth B, Richardson D, Clarke S, Gamble J, Bertolino P, Vadas M, Dong Q, Rasko J, Holst J, McCaughan G, Byrne S, Saunders B, Triccas J, Haass N, National Health and Medical Research Council (NHMRC)/Equipment Grant
- Predictors of Cancer Drug Metabolism, Clarke S, University of Sydney/Bridging Support
2007
- Inter-Ethnic Differences in Tolerance of Anti-Cancer drugs, Clarke S, McLachlan A, National Health and Medical Research Council (NHMRC)/Project Grants
2006
- Use of Proteomic Analyses to improve the management of colorectal cancer - the SCRIPT for CRC Projec, Baker M, Beale P, Bokey E, Chan C, Chapuis P, Christopherson R, Clarke S, Hong A, Horvath L, Kohonen-Corish M, Lin B, Mark M, McKay M, Robertson G, Solomon M, Cancer Institute NSW/Translational Program Grant
- Cognitive Function and Fatigue in cancer patients after chemotherapy, Vardy J, Clarke S, Tannock I, Schnitzler M, Dhillon H, National Health and Medical Research Council (NHMRC)/Project Grants
2004
- Repression of hepatic drug metabolism by solid tumours, Clarke S, Liddle C, Polly P, Robertson G, National Health and Medical Research Council (NHMRC)/Project Grants
- A randomised phase II trial of single agent irinotecan versus irinotecan plus De Gramont schedule 5- fluorouroacil and folinic acid, plus or minus celecoxib in patients with previously treated metastatic colorectal cancer (De Vinci), Clarke S, Clarke S, Conley R, Leaney N, Pfizer Australia Pty Ltd through AGITG/BLO Project
- ProteomeX MS and personnel support for the new facuility, Baxter R, Christopherson R, Clarke S, Daly R, Guilhaus M, Kavallaris M, Molloy M, Baker M, Cancer Institute NSW/Research Support
2003
- Impact of human cytochrome P450 3A allelic variants on the toxicity of docetaxel and irinotecan, Clarke S, Murray M, Ramzan I, University of Sydney/Cancer Research Fund
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