Mr Nicholas Everett
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Mr Nicholas Everett

Research Themes
  • Neurobiology of methamphetamine and opioid addiction
  • Neurobiology of social behaviour
  • Novel pharmacotherapies for substance use disorders
  • Translatable biomarkers of substance use disorders
  • Oxytocin
  • Psychedelics
  • Animal models of substance use disorders and social deficits
  • In vivo neuroimaging (fibre photometry)
  • Viral-mediated neural manipulations (CRISPR-Cas9; DREADDs; Optogenetics)

For a list of potential topics for interested students, please email me.

Postgraduate Supervision - Completed

  • Joel Raymond, PhD. The University of Sydney. The Social and Sleep Share a Two-way Sheet: Investigating the Reciprocal Dynamics Between Sleep, Social Behaviour, and Oxytocin. 2019-2023.
  • Rhianne Scicluna, PhD.The University of Sydney.Novel Pharmacotherapeutics for Opioid Addiction. 2019-2023.
  • Harry Carey, Masters of Research.The University of Sydney.DeepSlice: a deep neural network for rapid fully automatic registration of histological images to the Allen Mouse Brain Atlas. 2021-2022.
  • Tylah Doolan, Master of Brain and Mind Sciences. The University of Sydney.2021.

Postgraduate Supervision- Current

  • Tylah Doolan, PhD. The University of Sydney. 2022-2026.
  • Isabella Courtney, Master of Brain and Mind Sciences. The University of Sydney. 2023.

Undergraduate supervision - completed

  • Alex Athanasopoulos. The University of Sydney. Targeting the Oxytocin System to Promote Preference for Social Interaction over Alcohol Consumption in Rats. 2023.
  • Timothy Hill. Macquarie University. The effects of the melanocortin-4
    receptor agonist bremelanotide on methamphetamine self-administration and
    reinstatement in male rats. 2018.
  • International Behavioral Neuroscience Society (IBNS) - Executive Committee (ECR Rep)
  • European Behavioral Pharmacology Society (EBPS)
  • Biological Psychiatry Australia (BPA)
  • Addiction Neuroscience Australia (ANA) - Founder
  • World Congress on Neurohypophyseal Hormones (WCNH)
  • Hypothalamic Neuroscience and Neuroendocrinology Australasia (HNNA)
Prizes/Honours
  • Doris McIlwain Prize for Excellence in Psychology Research 2022
  • Vice-Chancellor's Commendation for Academic Excellence 2021
  • Lab Hero (Highly Commended), HelloBio, 2021
  • Best Publication, Biological Psychiatry Australia, 2021
  • Excellence in Higher Degree Research Award (University level), Macquarie University, 2020
  • Excellence in Higher Degree Research Award (Faculty level), Macquarie University, 2019
  • Best Abstract, Biological Psychiatry Australia, 2019

Notable presentations

  • Chair of opening Symposium at European Behavioral Pharmacology Society, 2023
  • Keynote representing the Brain and Mind Centre at the USyd Multi-disciplinary Institute showcase, 2023
  • Chair of symposium on novel addiction medications at Biologicla Psychiatry, 2023
  • Invited symposium presentation on oxytocin-based addiction medications at Society for Neuroscience, 2022
  • Invited to Gordon Research Conference on Neurobiology of Addiction, 2022
Learning, Neuroscience
Project titleResearch student
Exploring the therapeutic potential of psilocybin in methamphetamine addictionAlex ATHANASOPOULOS
Novel approaches for targeting the oxytocin system to treat methamphetamine addictionTylah DOOLAN

Publications

Journals

  • Raymond, J., Rehn, S., James, M., Everett, N., Bowen, M. (2024). Sex differences in the social motivation of rats: Insights from social operant conditioning, behavioural economics, and video tracking. Biology of Sex Differences, 15(1). [More Information]
  • Carey, H., Pegios, M., Martin, L., Saleeba, C., Turner, A., Everett, N., Bjerke, I., Puchades, M., Bjaalie, J., McMullan, S. (2023). DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas. Nature Communications, 14(1). [More Information]
  • Raymond, J., Everett, N., Gururajan, A., Bowen, M. (2023). Quiet wakefulness: the influence of intraperitoneal and intranasal oxytocin on sleep–wake behavior and neurophysiology in rats. Sleep, 46(7). [More Information]

2024

  • Raymond, J., Rehn, S., James, M., Everett, N., Bowen, M. (2024). Sex differences in the social motivation of rats: Insights from social operant conditioning, behavioural economics, and video tracking. Biology of Sex Differences, 15(1). [More Information]

2023

  • Carey, H., Pegios, M., Martin, L., Saleeba, C., Turner, A., Everett, N., Bjerke, I., Puchades, M., Bjaalie, J., McMullan, S. (2023). DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas. Nature Communications, 14(1). [More Information]
  • Raymond, J., Everett, N., Gururajan, A., Bowen, M. (2023). Quiet wakefulness: the influence of intraperitoneal and intranasal oxytocin on sleep–wake behavior and neurophysiology in rats. Sleep, 46(7). [More Information]

2022

  • Umpierrez, L., Costa, P., Michelutti, E., Baracz, S., Sauer, M., Turner, A., Everett, N., Arnold, J., McGregor, I., Cornish, J. (2022). Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses. Psychopharmacology, 239(5), 1593-1603. [More Information]
  • Baracz, S., Robinson, K., Wright, A., Turner, A., McGregor, I., Cornish, J., Everett, N. (2022). Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats. Neuropsychopharmacology, 47(8), 1561-1573. [More Information]
  • Webb, P., Hill, T., Everett, N., Thornton, J., Cornish, J., Baracz, S. (2022). The effect of adolescent social isolation on vulnerability for methamphetamine addiction behaviours in female rats. Psychopharmacology, 239(4), 1129-1141. [More Information]

2021

  • Thornton, J., Everett, N., Webb, P., Turner, A., Cornish, J., Baracz, S. (2021). Adolescent oxytocin administration reduces depression-like behaviour induced by early life stress in adult male and female rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 110, 110279. [More Information]
  • Everett, N., Turner, A., Costa, P., Baracz, S., Cornish, J. (2021). The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats. Neuropsychopharmacology, 46(2), 297-304. [More Information]

2020

  • Everett, N., Baracz, S. (2020). A piriform-orbitofrontal cortex pathway drives relapse to fentanyl-seeking after voluntary abstinence. Journal of Neuroscience, 40(43), 8208-8210. [More Information]
  • Green, T., Baracz, S., Everett, N., Robinson, K., Cornish, J. (2020). Differential effects of GABAA receptor activation in the prelimbic and orbitofrontal cortices on anxiety. Psychopharmacology, 237(11), 3237-3247. [More Information]
  • Baracz, S., Everett, N., Robinson, K., Campbell, G., Cornish, J. (2020). Maternal separation changes maternal care, anxiety-like behaviour and expression of paraventricular oxytocin and corticotrophin-releasing factor immunoreactivity in lactating rats. Journal of Neuroendocrinology, 32(6). [More Information]

2019

  • Everett, N., Baracz, S., Cornish, J. (2019). Oxytocin treatment in the prelimbic cortex reduces relapse to methamphetamine-seeking and is associated with reduced activity in the rostral nucleus accumbens core. Pharmacology, Biochemistry and Behavior, 183, 64-71. [More Information]

2018

  • Hay, G., Baracz, S., Everett, N., Roberts, J., Costa, P., Arnold, J., McGregor, I., Cornish, J. (2018). Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats. Journal of Psychopharmacology, 32(12), 1369-1378. [More Information]
  • Everett, N., McGregor, I., Baracz, S., Cornish, J. (2018). The role of the vasopressin V1A receptor in oxytocin modulation of methamphetamine primed reinstatement. Neuropharmacology, 133, 1-11. [More Information]

2016

  • Baracz, S., Parker, L., Suraev, A., Everett, N., Goodchild, A., McGregor, I., Cornish, J. (2016). Chronic Methamphetamine Self-Administration Dysregulates Oxytocin Plasma Levels and Oxytocin Receptor Fibre Density in the Nucleus Accumbens Core and Subthalamic Nucleus of the Rat. Journal of Neuroendocrinology, 28(4), 1-13. [More Information]
  • Baracz, S., Everett, N., McGregor, I., Cornish, J. (2016). Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine-seeking behaviour in rats. Addiction Biology, 21(2), 316-325. [More Information]

2015

  • Baracz, S., Everett, N., Cornish, J. (2015). The involvement of oxytocin in the subthalamic nucleus on relapse to methamphetamine-seeking behaviour. PloS One, 10(8), 1-17. [More Information]

Selected Grants

2023

  • Developing novel strategies for stimulating the oxytocin system to treat methamphetamine addiction., Everett N, National Health and Medical Research Council (NHMRC)/Investigator Grant
  • Developing safe and efficacious non-hallucinogenic 5-HT2A agonists - Psylo Pty Ltd - Nicholas Everett, Everett N, Brain and Mind Centre/Brain and Mind Centre Partnership Grant

2022

  • Presenting research at European Behavioral Pharmacology Society Meeting 2023, Everett N, Brain and Mind Centre/Early and Mid-Career Researcher Travel Grant

Key External Partnerships:

  • Kinoxis Therapeutics Pty Ltd
  • Boehringer Ingelheim
  • Psylo

Key Internal Partnerships:

  • A/Prof Michael Bowen