Dr Suzanne Mithieux
People_

Dr Suzanne Mithieux

Postdoctoral Fellow
School of Life and Environmental Sciences
Phone
+61 2 9351 7333
Address
D17 - Charles Perkins Centre
The University of Sydney
Details
Healthy Ageing
Project titleResearch student
CRIP1 as a Response Molecule to Tropoelastin and the Intracellular Signalling Transduction MechanismJade CHEN
Anisotropic MeTro/GelMa cryogel for tendon regeneration.Miao ZHANG

Publications

Book Chapters

  • Wang, R., Mithieux, S., Ozsvar, J., Weiss, A. (2016). Synthetic-Elastin Systems. In Not known (Eds.), Elastic Fiber Matrices: Biomimetic Approaches to Regeneration and Repair, (pp. 81-115). TBC. [More Information]

Journals

  • Wang, Z., Zhang, M., Liu, L., Mithieux, S., Weiss, A. (2024). Polyglycerol sebacate-based elastomeric materials for arterial regeneration. Journal of Biomedical Materials Research A, 112(4), 574-585. [More Information]
  • Wang, Z., Weiss, A., Mithieux, S., Blum, K., Yi, T., Matsuzaki, Y., Pham, T., Hawkett, B., Shinoka, T., Breuer, C. (2024). Regional Differences in Vascular Graft Degradation and Regeneration Contribute to Dilation. Tissue Engineering - Part A. [More Information]
  • Wang, Z., Shi, H., Silveira, P., Mithieux, S., Cheng Wong, W., Liu, L., Pham, T., Hawkett, B., Wang, Y., Weiss, A. (2024). Tropoelastin modulates systemic and local tissue responses to enhance wound healing. Acta Biomaterialia, 184, 54-67. [More Information]

Conferences

  • Van der Saag, D., Mithieux, S., Weiss, A., White, P. (2018). Improving animal health and welfare in extensive livestock industries: A collaborative solution between veterinary science and human biomedical engineering disciplines. Collaboration across boundaries 2018 – A Theory Murphy Initiative, Canberra , Australia, Australia.
  • Momot, K., Powell, S., Mithieux, S., Weiss, A. (2013). Biomechanics of Synthetic Elastin: Insights from Magnetic Resonance Microimaging. 2013 International Conference on Materials Science and Chemical Engineering (MSCE 2013), Durnten-Zurich, Switzerland: Trans Tech Publications. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2008). Fabrication of a crosslinked hydrogel using dense gas technology. 2008 Materials Research Society (MRS) Fall Meeting, Boston, USA: Materials Research Society.

Patents

  • Fathi, A., Weiss, A., Dehghani, F., Mithieux, S. (2021). Application of Thermoresponsive Bioactive Injectable Hydrogel for Bone Regeneration. Patent No. 2016314146, 6851377, EP3344304.
  • Weiss, A., Mithieux, S. (2019). Promoting Elastic Tissue Assembly. Patent No. 2012315489, 2760466.
  • Weiss, A., Mithieux, S. (2018). Injectable Biomaterials. Patent No. 2787849. Canada.

2024

  • Wang, Z., Zhang, M., Liu, L., Mithieux, S., Weiss, A. (2024). Polyglycerol sebacate-based elastomeric materials for arterial regeneration. Journal of Biomedical Materials Research A, 112(4), 574-585. [More Information]
  • Wang, Z., Weiss, A., Mithieux, S., Blum, K., Yi, T., Matsuzaki, Y., Pham, T., Hawkett, B., Shinoka, T., Breuer, C. (2024). Regional Differences in Vascular Graft Degradation and Regeneration Contribute to Dilation. Tissue Engineering - Part A. [More Information]
  • Wang, Z., Shi, H., Silveira, P., Mithieux, S., Cheng Wong, W., Liu, L., Pham, T., Hawkett, B., Wang, Y., Weiss, A. (2024). Tropoelastin modulates systemic and local tissue responses to enhance wound healing. Acta Biomaterialia, 184, 54-67. [More Information]

2023

  • Hume, R., Kanagalingam, S., Deshmukh, T., Chen, S., Mithieux, S., Rashid, F., Roohani, I., Lu, J., Doan, T., Graham, J., Clayton, Z., Kizana, E., Thomas, L., Weiss, A., Chong, J., et al (2023). Tropoelastin Improves Post-Infarct Cardiac Function by Increasing Scar Elastin. Circulation Research, 132(1), 72-86. [More Information]

2022

  • Zhang, M., Wang, Z., Zhang, A., Liu, L., Mithieux, S., Bilek, M., Weiss, A. (2022). Development of tropoelastin-functionalized anisotropic PCL scaffolds for musculoskeletal tissue engineering. Regenerative Biomaterials, 10, 1-9. [More Information]
  • Roohani, I., Yeo, G., Mithieux, S., Weiss, A. (2022). Emerging concepts in bone repair and the premise of soft materials. Current Opinion in Biotechnology, 74, 220-229. [More Information]
  • Al Halawani, A., Mithieux, S., Yeo, G., Hosseini Beheshti, E., Weiss, A. (2022). Extracellular Vesicles: Interplay with the Extracellular Matrix and Modulated Cell Responses. International Journal of Molecular Sciences, 23(6). [More Information]

2021

  • Almeida-González, F., González-Vázquez, A., Mithieux, S., O'Brien, F., Weiss, A., Brougham, C. (2021). A step closer to elastogenesis on demand; Inducing mature elastic fibre deposition in a natural biomaterial scaffold. Materials Science and Engineering C, 120, 111788. [More Information]
  • Fathi, A., Weiss, A., Dehghani, F., Mithieux, S. (2021). Application of Thermoresponsive Bioactive Injectable Hydrogel for Bone Regeneration. Patent No. 2016314146, 6851377, EP3344304.
  • Wang, Z., Liu, L., Mithieux, S., Weiss, A. (2021). Fabricating Organized Elastin in Vascular Grafts. Trends in Biotechnology, 39(5), 505-518. [More Information]

2020

  • Aghaei-Ghareh-Bolagh, B., Mukherjee, S., Lockley, K., Mithieux, S., Wang, Z., Emmerson, S., Darzi, S., Gargett, C., Weiss, A. (2020). A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair. Materials Today Bio, 8, 1-11. [More Information]
  • Wen, Q., Mithieux, S., Weiss, A. (2020). Elastin Biomaterials in Dermal Repair. Trends in Biotechnology, 38(3), 280-291. [More Information]
  • Mitzmacher, M., Mithieux, S., Weiss, A., Hee, C., Daniels, R. (2020). Novel recombinant tropoelastin implants restore skin extracellular matrix. Journal of Drugs in Dermatology: new methods and technology, 19(12), 1166-1172. [More Information]

2019

  • Vindin, H., Mithieux, S., Weiss, A. (2019). Elastin architecture. Matrix Biology, 84, 4-16. [More Information]
  • Aghaei-Ghareh-Bolagh, B., Mithieux, S., Hiob, M., Wang, Y., Chong, A., Weiss, A. (2019). Fabricated tropoelastin-silk yarns and woven textiles for diverse tissue engineering applications. Acta Biomaterialia, 91, 112-122. [More Information]
  • Wang, Z., Mithieux, S., Weiss, A. (2019). Fabrication Techniques for Vascular and Vascularized Tissue Engineering. Advanced Healthcare Materials, 8(19), 1-26. [More Information]

2018

  • Pesqueira, T., Costa-Almeida, R., Mithieux, S., Babo, P., Franco, A., Mendes, B., Domingues, R., Freitas, P., Reis, R., Gomes, M., Weiss, A. (2018). Engineering magnetically responsive tropoelastin spongy-like hydrogels for soft tissue regeneration. Journal of Materials Chemistry B, 6(7), 1066-1075. [More Information]
  • Van der Saag, D., Mithieux, S., Weiss, A., White, P. (2018). Improving animal health and welfare in extensive livestock industries: A collaborative solution between veterinary science and human biomedical engineering disciplines. Collaboration across boundaries 2018 – A Theory Murphy Initiative, Canberra , Australia, Australia.
  • Weiss, A., Mithieux, S. (2018). Injectable Biomaterials. Patent No. 2787849. Canada.

2017

  • Fathi, A., Weiss, A., Dehghani, F., Wei, H., Mithieux, S. (2017). Design of a New Crosslinker for Biopolymer Hydrogel Fabrication. Patent No. 2794701, 9546235. , Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom.
  • Mithieux, S., Weiss, A. (2017). Design of an elastin-layered dermal regeneration template. Acta Biomaterialia, 52, 33-40. [More Information]
  • Annabi, N., Rana, D., Shirzaei Sani, E., Portillo-Lara, R., Gifford, J., Fares, M., Mithieux, S., Weiss, A. (2017). Engineering a sprayable and elastic hydrogel adhesive with antimicrobial properties for wound healing. Biomaterials, 139, 229-243. [More Information]

2016

  • Aghaei Ghareh Bolagh, B., Mithieux, S., Weiss, A. (2016). Elastic proteins and elastomeric protein alloys. Current Opinion in Biotechnology, 39, 56-60. [More Information]
  • Annabi, N., Shin, S., Tamayol, A., Miscuglio, M., Bakooshli, M., Assmann, A., Mostafalu, P., Sun, J., Mithieux, S., Cheung, L., Weiss, A., et al (2016). Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels. Advanced Materials, 28(1), 40-49. [More Information]
  • Wang, R., Mithieux, S., Ozsvar, J., Weiss, A. (2016). Synthetic-Elastin Systems. In Not known (Eds.), Elastic Fiber Matrices: Biomimetic Approaches to Regeneration and Repair, (pp. 81-115). TBC. [More Information]

2015

  • Ozsvar, J., Mithieux, S., Wang, R., Weiss, A. (2015). Elastin-based biomaterials and mesenchymal stem cells. Biomaterials Science, 3(6), 800-809. [More Information]
  • Wang, Y., Mithieux, S., Kong, Y., Wang, X., Chong, C., Fathi, A., Dehghani, F., Panas, E., Kemnitzer, J., Daniels, R., Maitz, P., Li, Z., Weiss, A., et al (2015). Tropoelastin incorporation into a dermal regeneration template promotes wound angiogenesis. Advanced Healthcare Materials, 4(4), 577-584. [More Information]
  • Wang, Y., Mithieux, S., Kong, Y., Wang, X., Chong, C., Fathi, A., Dehghani, F., Panas, E., Kemnitzer, J., Daniels, R., Maitz, P., Li, Z., Weiss, A., et al (2015). Wound healing: tropoelastin incorporation into a dermal regeneration template promotes wound angiogenesis (adv. Healthcare mater. 4/2015). Advanced Healthcare Materials, 4(4), 576-576.

2014

  • Fathi, A., Mithieux, S., Wei, H., Chrzanowski, W., Valtchev, P., Weiss, A., Dehghani, F. (2014). Elastin based cell-laden injectable hydrogels with tunable gelation, mechanical and biodegradation properties. Biomaterials, 35(21), 5425-5435. [More Information]
  • Heinz, A., Schrader, C., Baud, S., Keeley, F., Mithieux, S., Weiss, A., Neubert, R., Schmelzer, C. (2014). Molecular-level characterization of elastin-like constructs and human aortic elastin. Matrix Biology, 38, 12-21. [More Information]

2013

  • Momot, K., Powell, S., Mithieux, S., Weiss, A. (2013). Biomechanics of Synthetic Elastin: Insights from Magnetic Resonance Microimaging. 2013 International Conference on Materials Science and Chemical Engineering (MSCE 2013), Durnten-Zurich, Switzerland: Trans Tech Publications. [More Information]
  • Annabi, N., Mithieux, S., Camci-Unal, G., Dokmeci, M., Weiss, A., Khademhosseini, A. (2013). Elastomeric recombinant protein-based biomaterials. Biochemical Engineering Journal, 77, 110-118. [More Information]
  • Annabi, N., Mithieux, S., Zorlutuna, P., Camci-Unal, G., Weiss, A., Khademhosseini, A. (2013). Engineered cell-laden human protein-based elastomer. Biomaterials, 34(22), 5496-5505. [More Information]

2012

  • Weiss, A., Mithieux, S., Regaglia, O. (2012). Protease Susceptibility II (Canada). Patent No. 2335098, 7229788. , Canada.
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012). Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences of the United States of America, 109(8), 2878-2883. [More Information]
  • Weiss, A., Mithieux, S., Regaglia, O. (2012). Tropoelastin Derivatives (Canada). Patent No. 2296841, 636948, 7193043. , Canada, Republic of Korea.

2011

  • Annabi, N., Fathi, A., Mithieux, S., Weiss, A., Dehghani, F. (2011). Fabrication of Porous PCL/elastin Composite Scaffolds for Tissue Engineering Applications. The Journal of Supercritical Fluids, 59, 157-167. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Mithieux, S., Weiss, A. (2011). Severe burn injuries and the role of elastin in the design of dermal substitutes. Tissue Engineering. Part B. Reviews, 17(2), 81-91. [More Information]
  • Baldock, C., Oberhauser, A., Ma, L., Lammie, D., Siegler, V., Mithieux, S., Tu, Y., Chow, J., Suleman, F., Malfois, M., Weiss, A., et al (2011). Shape of Tropoelastin, the Highly Extensible Protein That Controls Human Tissue Elasticity. Proceedings of the National Academy of Sciences of the United States of America, 108(11), 4322-4327. [More Information]

2010

  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2010). Cross-linked open-pore elastic hydrogels based on tropoelastin, elastin and high pressure CO(2). Biomaterials, 31(7), 1655-1665. [More Information]
  • Almine, J., Bax, D., Mithieux, S., Nivison-Smith, L., Rnjak-Kovacina, J., Waterhouse, A., Wise, S., Weiss, A. (2010). Elastin-based materials. Chemical Society Reviews, 39(9), 3371-3379. [More Information]
  • Tu, Y., Mithieux, S., Annabi, N., Boughton, E., Weiss, A. (2010). Synthetic elastin hydrogels that are coblended with heparin display substantial swelling, increased porosity, and improved cell penetration. Journal of Biomedical Materials Research A, 95A(4), 1215-1222. [More Information]

2009

  • Naumann, C., Mithieux, S., Szekely, D., Tu, Y., Weiss, A., Kuchel, P. (2009). "Setting paint" analogy for the hydrophobic self-association of tropoelastin into elastin-like hydrogel. Biopolymers (Peptide Science), 91(5), 321-330. [More Information]
  • Wise, S., Mithieux, S., Weiss, A. (2009). Engineered tropoelastin and elastin-based biomaterials. Advances in Protein Chemistry and Structural Biology.
  • Mithieux, S., Tu, Y., Korkmaz, E., Braet, F., Weiss, A. (2009). In situ polymerization of tropoelastin in the absence of chemical cross-linking. Biomaterials, 30(4), 431-435. [More Information]

2008

  • Dehghani, F., Annabi, N., Valtchev, P., Mithieux, S., Weiss, A., Kazarian, S., Tay, F. (2008). Effect of dense gas CO2 on the coacervation of elastin. Biomacromolecules, 9(4), 1100-1105. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2008). Fabrication of a crosslinked hydrogel using dense gas technology. 2008 Materials Research Society (MRS) Fall Meeting, Boston, USA: Materials Research Society.
  • Weiss, A., Mithieux, S., Regaglia, O. (2008). Synthetic Polynucleotides. Patent No. 0746612. , France, Germany, Italy, Sweden, Switzerland, United Kingdom.

2006

  • Clarke, A., Arnspang, E., Mithieux, S., Korkmaz, E., Braet, F., Weiss, A. (2006). Tropoelastin Massively Associates during Coacervation To Form Quantized Protein Spheres. Biochemistry, 45(33), 9989-9996. [More Information]

2005

  • Mithieux, S., Wise, S., Raftery, M., Starcher, B., Weiss, A. (2005). A model two-component system for studying the architecture of elastin assembly in vitro. Journal of Structural Biology, 149(3), 282-289. [More Information]
  • Mithieux, S., Weiss, A. (2005). Elastin. Advances in protein chemistry, 70, 437-461. [More Information]
  • Gheduzzi, D., Guerra, D., Bochicchio, B., Pepe, A., Tamburro, A., Quaglino, D., Mithieux, S., Weiss, A., Ronchetti, I. (2005). Heparan sulphate interacts with tropoelastin, with some tropoelastin peptides and is present in human dermis elastic fibers. Matrix Biology, 24(1), 15-25. [More Information]

2004

  • Mithieux, S., Rasko, J., Weiss, A. (2004). Synthetic Elastin Hydrogels Derived From Massive Elastic Assemblies Of Self-Organized Human Protein Monomers. Biomaterials, 25(20), 4921-4927. [More Information]

2001

  • Weiss, A., Mithieux, S., Stone,, P., Morris, S., Griffin, S. (2001). Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic Rat-1 fibroblasts as a source for lysyl oxidase. American Journal of Respiratory Cell and Molecular Biology, 24, 733-739.