People_

Dr Adrian Lee

BSc (Med) MBBS (Hons) FRACP PhD

Clinical Senior Lecturer
Sydney Medical School
Faculty of Medicine and Health

Email

adrian.lee@sydney.edu.au

Dr Lee is a Medical Oncologist and Network Director of Physician Training at Royal North Shore Hospital and Genesis Care. He has clinical and research interests in neuro-oncology, head and neck and genitourinary cancers. He is currently an Executive Member of the Medical Oncology Group of Australia (MOGA) and Chair of the State Committee in the Royal Australasian College of Physicians (RACP).

Research interests

Neuro-oncology

Liquid Biopsy

Genitourinary cancers

Head and Neck Cancers

Teaching and supervision

Basic Physician Training

Medical Oncology Advanced Training

Associations

MOGA

RACP

COGNO

ASCO

ESMO

International links

United States

(Memorial Sloan Kettering Cancer Centre) Collaboration in liquid biopsy - ctDNA in advanced cancers

Current research students

Project title	Research student
Understanding the role of de-escalation strategies in patients undergoing radiation therapy for mucosal squamous cell carcinomas of the head and neck.	Anna LAWLESS

Publications

By Type

Expand all

Journals

Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
Kumar, S., Crumbaker, M., Harvey, C., Pathmanandavel, S., John, N., Swiha, M., Ittimani, C., Clifton-Bligh, R., Lee, A., Bastick, P., et al (2023). The Tyr Phenomenon: A Hypocalcemic Response in High-Volume Treatment Responders to 177Lu-Prostate-Specific Membrane Antigen Therapy. The Journal of Nuclear Medicine, 64(9), 1412-1416. [More Information]
Yuile, A., Satgunaseelan, L., Wei, J., Kastelan, M., Back, M., Lee, M., Wei, G., Buckland, M., Lee, A., Wheeler, H. (2022). Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma—A Case Report and Systematic Review. Current Issues in Molecular Biology (Print), 44(10), 5117-5125. [More Information]
Yuile, A., Khasraw, M., Low, J., Walsh, K., Lipp, E., Sy, J., Satgunaseelan, L., Kastelan, M., De Silva, M., Lee, A., et al (2022). Patterns of care in adult histone mutant gliomas: Results of an international survey. Neuro-Oncology Practice, 9(6), 520-525. [More Information]
Mondaca, S., Lebow, E., Namakydoust, A., Razavi, P., Reis-Filho, J., Shen, R., Offin, M., Tu, H., Murciano-Goroff, Y., Xu, C., Pavlakis, N., Clarke, S., Itchins, M., Lee, A., et al (2021). Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions. Lung Cancer, 159, 66-73. [More Information]
Wijetunga, A., Lee, A., Jayamanne, D. (2021). PEG site metastasis in oropharyngeal squamous cell carcinoma managed with cetuximab and radiotherapy: A case report. Current Problems in Cancer, 45(5), 100700. [More Information]
Alexander, M., Pavlakis, N., John, T., O'Connell, R., Kao, S., Hughes, B., Lee, A., Hayes, S., Howell, V., Clarke, S., Itchins, M., et al (2020). A multicenter study of thromboembolic events among patients diagnosed with ROS1-rearranged non-small cell lung cancer. Lung Cancer, 142, 34-40. [More Information]
Chan, D., Espinoza, D., Chan, J., Lee, A., Faisal, W., Segelov, E., Pavlakis, N. (2020). Adjuvant anti-VEGF therapy for overall survival and relapse-free survival in patients with resected non-metastatic colorectal cancer. Cochrane Database of Systematic Reviews, 2020 (3), CD012460. [More Information]
Lee, A., Arasaratnam, M., Chan, D., Khasraw, M., Howell, V., Wheeler, H. (2020). Anti-epidermal growth factor receptor therapy for glioblastoma in adults. Cochrane Database of Systematic Reviews, 2020 (5), CD013238. [More Information]
Sabari, J., Offin, M., Stephens, D., Ni, A., Lee, A., Pavlakis, N., Clarke, S., Diakos, C., Datta, S., Tandon, N., et al (2019). A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers. Journal of the National Cancer Institute, 111(6), 1-9. [More Information]
Lee, A., Arasaratnam, M., Chan, D., Khasraw, M., Howell, V., Wheeler, H. (2019). Anti-epidermal growth factor receptor therapy for glioblastoma in adults. Cochrane Database of Systematic Reviews, 2019 (1), 1-13. [More Information]
Van Gysen, K., Stevens, M., Guo, L., Jayamanne, D., Veivers, D., Wignall, A., Pang, L., Guminski, A., Lee, A., Hruby, G., Taylor, A., et al (2019). Validation of the 8th edition UICC/AJCC TNM staging system for HPV associated oropharyngeal cancer patients managed with contemporary chemo-radiotherapy. BMC Cancer, 19(1), 1-8. [More Information]
Wong, E., Jacques, S., Bennett, M., Gorolay, V., Lee, A., Clarke, S. (2018). Complete response in a patient with stage IV adrenocortical carcinoma treated with adjuvant trans-catheter arterial chemo-embolization (TACE). Asia-Pacific Journal of Clinical Oncology, 14(3), 279-281. [More Information]
Reslan, Z., Bennett, M., Wong, E., Jacques, S., Lee, A. (2018). Pembrolizumab-induced auto-immune type-1 diabetes in a patient with metastatic melanoma. Journal of Pharmacy Practice and Research, 48(3), 262-264. [More Information]
Lee, A., Howell, V., Itchins, M., Wheeler, H., Pavlakis, N. (2018). ROS1-Rearranged Non-Small-Cell Lung Cancer, Factor V Leiden, and Recurrent Venous Thromboses. Clinical Lung Cancer, 19(5), 457-459. [More Information]
Cho, A., McKelvey, K., Lee, A., Hudson, A. (2018). The intertwined fates of inflammation and coagulation in glioma. Mammalian Genome, 29, 806-816. [More Information]
Lee, A., Chan, D., Wong, M., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2017). Systematic Review of the Role of Targeted Therapy in Metastatic Neuroendocrine Tumors. Neuroendocrinology, 104(3), 209-222. [More Information]
Khasraw, M., Lee, A., McCowatt, S., Kerestes, Z., Buyse, M., Back, M., Kichenadasse, G., Ackland, S., Wheeler, H. (2016). Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial. Journal of Neuro-Oncology, 128(1), 163-171. [More Information]
Bailey, D., Lee, A., Li, B., Clarke, S. (2016). PET monitoring of liver directed selective internal radionuclide therapy for metastatic gastro-oesophageal cancer. BMJ Case Reports, 2016, bcr2016215645. [More Information]
Wong, E., Oh, L., Nahar, K., Lee, A., Clarke, S. (2016). Primary Pericardial Sarcoma with Right Atrial Invasion and Multiple Bilateral Pulmonary Metastases in a Patient with Hereditary Nonpolyposis Colorectal Cancer. Case Reports in Oncological Medicine, 2016. [More Information]
Wong, M., Chan, D., Lee, A., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2016). Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET). PloS One, 11(6), 1-15. [More Information]
Li, B., Barnes, T., Chan, D., Naidoo, J., Lee, A., Khasraw, M., Marx, G., Kris, M., Clarke, S., Drilon, A., Pavlakis, N., et al (2016). The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials. Lung Cancer, 102, 21-27. [More Information]
Li, B., Lee, A., O'Toole, S., Cooper, W., Yu, B., Chaft, J., Arcila, M., Kris, M., Pavlakis, N. (2015). HER2 insertion YVMA mutant lung cancer: Long natural history and response to afatinib. Lung Cancer, 90(3), 617-619. [More Information]
Li, B., Pearson, A., Pavlakis, N., Bell, D., Lee, A., Chan, D., Harden, M., Mathur, M., Marshman, D., Brady, P., Clarke, S. (2014). Malignant Cardiac Tamponade from Non-Small Cell Lung Cancer: Case Series from the Era of Molecular Targeted Therapy. Journal of Clinical Medicine, 4(1), 75-84. [More Information]
Johnston, M., Guo, L., Back, M., Guminski, A., Lee, A., Hanna, C., Veivers, D., Wignall, A., Eade, T. (2013). Intensity-modulated radiotherapy using simultaneous-integrated boost for definitive treatment of locally advanced mucosal head and neck cancer: Outcomes from a single-institution series. Journal of Medical Imaging and Radiation Oncology, 57(3), 356-363. [More Information]

show 22 more

By Year

Expand all

2023

Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
Kumar, S., Crumbaker, M., Harvey, C., Pathmanandavel, S., John, N., Swiha, M., Ittimani, C., Clifton-Bligh, R., Lee, A., Bastick, P., et al (2023). The Tyr Phenomenon: A Hypocalcemic Response in High-Volume Treatment Responders to 177Lu-Prostate-Specific Membrane Antigen Therapy. The Journal of Nuclear Medicine, 64(9), 1412-1416. [More Information]

2022

Yuile, A., Satgunaseelan, L., Wei, J., Kastelan, M., Back, M., Lee, M., Wei, G., Buckland, M., Lee, A., Wheeler, H. (2022). Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma—A Case Report and Systematic Review. Current Issues in Molecular Biology (Print), 44(10), 5117-5125. [More Information]
Yuile, A., Khasraw, M., Low, J., Walsh, K., Lipp, E., Sy, J., Satgunaseelan, L., Kastelan, M., De Silva, M., Lee, A., et al (2022). Patterns of care in adult histone mutant gliomas: Results of an international survey. Neuro-Oncology Practice, 9(6), 520-525. [More Information]

2021

Mondaca, S., Lebow, E., Namakydoust, A., Razavi, P., Reis-Filho, J., Shen, R., Offin, M., Tu, H., Murciano-Goroff, Y., Xu, C., Pavlakis, N., Clarke, S., Itchins, M., Lee, A., et al (2021). Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions. Lung Cancer, 159, 66-73. [More Information]
Wijetunga, A., Lee, A., Jayamanne, D. (2021). PEG site metastasis in oropharyngeal squamous cell carcinoma managed with cetuximab and radiotherapy: A case report. Current Problems in Cancer, 45(5), 100700. [More Information]

2020

Alexander, M., Pavlakis, N., John, T., O'Connell, R., Kao, S., Hughes, B., Lee, A., Hayes, S., Howell, V., Clarke, S., Itchins, M., et al (2020). A multicenter study of thromboembolic events among patients diagnosed with ROS1-rearranged non-small cell lung cancer. Lung Cancer, 142, 34-40. [More Information]
Chan, D., Espinoza, D., Chan, J., Lee, A., Faisal, W., Segelov, E., Pavlakis, N. (2020). Adjuvant anti-VEGF therapy for overall survival and relapse-free survival in patients with resected non-metastatic colorectal cancer. Cochrane Database of Systematic Reviews, 2020 (3), CD012460. [More Information]
Lee, A., Arasaratnam, M., Chan, D., Khasraw, M., Howell, V., Wheeler, H. (2020). Anti-epidermal growth factor receptor therapy for glioblastoma in adults. Cochrane Database of Systematic Reviews, 2020 (5), CD013238. [More Information]

2019

Sabari, J., Offin, M., Stephens, D., Ni, A., Lee, A., Pavlakis, N., Clarke, S., Diakos, C., Datta, S., Tandon, N., et al (2019). A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers. Journal of the National Cancer Institute, 111(6), 1-9. [More Information]
Lee, A., Arasaratnam, M., Chan, D., Khasraw, M., Howell, V., Wheeler, H. (2019). Anti-epidermal growth factor receptor therapy for glioblastoma in adults. Cochrane Database of Systematic Reviews, 2019 (1), 1-13. [More Information]
Van Gysen, K., Stevens, M., Guo, L., Jayamanne, D., Veivers, D., Wignall, A., Pang, L., Guminski, A., Lee, A., Hruby, G., Taylor, A., et al (2019). Validation of the 8th edition UICC/AJCC TNM staging system for HPV associated oropharyngeal cancer patients managed with contemporary chemo-radiotherapy. BMC Cancer, 19(1), 1-8. [More Information]

2018

Wong, E., Jacques, S., Bennett, M., Gorolay, V., Lee, A., Clarke, S. (2018). Complete response in a patient with stage IV adrenocortical carcinoma treated with adjuvant trans-catheter arterial chemo-embolization (TACE). Asia-Pacific Journal of Clinical Oncology, 14(3), 279-281. [More Information]
Reslan, Z., Bennett, M., Wong, E., Jacques, S., Lee, A. (2018). Pembrolizumab-induced auto-immune type-1 diabetes in a patient with metastatic melanoma. Journal of Pharmacy Practice and Research, 48(3), 262-264. [More Information]
Lee, A., Howell, V., Itchins, M., Wheeler, H., Pavlakis, N. (2018). ROS1-Rearranged Non-Small-Cell Lung Cancer, Factor V Leiden, and Recurrent Venous Thromboses. Clinical Lung Cancer, 19(5), 457-459. [More Information]
Cho, A., McKelvey, K., Lee, A., Hudson, A. (2018). The intertwined fates of inflammation and coagulation in glioma. Mammalian Genome, 29, 806-816. [More Information]

show 1 more

2017

Lee, A., Chan, D., Wong, M., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2017). Systematic Review of the Role of Targeted Therapy in Metastatic Neuroendocrine Tumors. Neuroendocrinology, 104(3), 209-222. [More Information]

2016

Khasraw, M., Lee, A., McCowatt, S., Kerestes, Z., Buyse, M., Back, M., Kichenadasse, G., Ackland, S., Wheeler, H. (2016). Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial. Journal of Neuro-Oncology, 128(1), 163-171. [More Information]
Bailey, D., Lee, A., Li, B., Clarke, S. (2016). PET monitoring of liver directed selective internal radionuclide therapy for metastatic gastro-oesophageal cancer. BMJ Case Reports, 2016, bcr2016215645. [More Information]
Wong, E., Oh, L., Nahar, K., Lee, A., Clarke, S. (2016). Primary Pericardial Sarcoma with Right Atrial Invasion and Multiple Bilateral Pulmonary Metastases in a Patient with Hereditary Nonpolyposis Colorectal Cancer. Case Reports in Oncological Medicine, 2016. [More Information]
Wong, M., Chan, D., Lee, A., Li, B., Lumba, S., Clarke, S., Samra, J., Pavlakis, N. (2016). Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET). PloS One, 11(6), 1-15. [More Information]
Li, B., Barnes, T., Chan, D., Naidoo, J., Lee, A., Khasraw, M., Marx, G., Kris, M., Clarke, S., Drilon, A., Pavlakis, N., et al (2016). The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials. Lung Cancer, 102, 21-27. [More Information]

show 2 more

2015

Li, B., Lee, A., O'Toole, S., Cooper, W., Yu, B., Chaft, J., Arcila, M., Kris, M., Pavlakis, N. (2015). HER2 insertion YVMA mutant lung cancer: Long natural history and response to afatinib. Lung Cancer, 90(3), 617-619. [More Information]

2014

Li, B., Pearson, A., Pavlakis, N., Bell, D., Lee, A., Chan, D., Harden, M., Mathur, M., Marshman, D., Brady, P., Clarke, S. (2014). Malignant Cardiac Tamponade from Non-Small Cell Lung Cancer: Case Series from the Era of Molecular Targeted Therapy. Journal of Clinical Medicine, 4(1), 75-84. [More Information]

2013

Johnston, M., Guo, L., Back, M., Guminski, A., Lee, A., Hanna, C., Veivers, D., Wignall, A., Eade, T. (2013). Intensity-modulated radiotherapy using simultaneous-integrated boost for definitive treatment of locally advanced mucosal head and neck cancer: Outcomes from a single-institution series. Journal of Medical Imaging and Radiation Oncology, 57(3), 356-363. [More Information]

Selected Grants

2022