People_
Professor Alison Brand
MD, MMEd, FRCS(C), FRANZCOG, CGO
Member Order of Australia (AM)
Clinical Professor
Director | Gynaecological Oncology
Westmead Hospital PO Box 533 Wentworthville 2145
Clinical Professor
Director | Gynaecological Oncology
Westmead Hospital PO Box 533 Wentworthville 2145
Cancer, Reproductive, Maternal and Child Health
Publications
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Journals
- Noori, N., Edwards, L., Anpalagan, A., Athavale, R., Burling, M., Herbst, U., Brand, A., Kapurubandara, S. (2023). Bilateral salpingectomy as an option of permanent contraception at time of caesarean section: A survey of practice. Australian and New Zealand Journal of Obstetrics and Gynaecology. [More Information]
- Kang, E., Weir, A., Meagher, N., Farrington, K., Nelson, G., Ghatage, P., Lee, C., Riggan, M., Bolithon, A., Popovic, G., Boros, J., Brand, A., et al (2023). CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study. Cancer, 129.0(5), 697-713. [More Information]
- Boo, M., Simcock, B., Sykes, P., Brand, A. (2023). Direct oral anticoagulants (DOACs) use for prolonged venous thromboembolism prophylaxis following surgery for gynaecological malignancies in Australia and New Zealand - A clinician survey. Australian and New Zealand Journal of Obstetrics and Gynaecology. [More Information]
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2023
- Noori, N., Edwards, L., Anpalagan, A., Athavale, R., Burling, M., Herbst, U., Brand, A., Kapurubandara, S. (2023). Bilateral salpingectomy as an option of permanent contraception at time of caesarean section: A survey of practice. Australian and New Zealand Journal of Obstetrics and Gynaecology. [More Information]
- Kang, E., Weir, A., Meagher, N., Farrington, K., Nelson, G., Ghatage, P., Lee, C., Riggan, M., Bolithon, A., Popovic, G., Boros, J., Brand, A., et al (2023). CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study. Cancer, 129.0(5), 697-713. [More Information]
- Boo, M., Simcock, B., Sykes, P., Brand, A. (2023). Direct oral anticoagulants (DOACs) use for prolonged venous thromboembolism prophylaxis following surgery for gynaecological malignancies in Australia and New Zealand - A clinician survey. Australian and New Zealand Journal of Obstetrics and Gynaecology. [More Information]
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2022
- Kairaitis, K., Madut, A., Subramanian, H., Trivedi, R., Man, H., Mather, M., Brand, A., Elder, E., Howle, J., Mann, G., Amis, T., deFazio, A. (2022). Cancer sleep symptom-related phenotypic clustering differs across three cancer specific patient cohorts. Journal of Sleep Research. [More Information]
- Cunningham, J., Winham, S., Wang, C., Weiglt, B., Fu, Z., Armasu, S., McCauley, B., Brand, A., Chiew, Y., Elishaev, E., deFazio, A., et al (2022). DNAMethylation Profiles of Ovarian Clear Cell Carcinoma. Cancer Epidemiology Biomarkers and Prevention, 31(1), 132-141. [More Information]
- Cohen, P., Webb, P., King, M., Obermair, A., Gebski, V., Butow, P., Morton, R., Lawson, W., Yates, P., Campbell, R., Brand, A., et al (2022). Getting the MOST out of follow-up: a randomized controlled trial comparing 3 monthly nurse led follow-up via telehealth, including monitoring CA125 and patient reported outcomes using the MOST (Measure of Ovarian Symptoms and Treatment concerns) with routine clinic based or telehealth follow-up, after completion of first line chemotherapy in patients with epithelial ovarian cancer. International Journal of Gynecological Cancer, 32(4), 560-565. [More Information]
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2021
- Glubb, D., Thompson, D., Aben, K., Alsulimani, A., Amant, F., Annibali, D., Attia, J., Barricarte, A., Beckmann, M., Berchuck, A., deFazio, A., Gao, B., Brand, A., et al (2021). Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers. Cancer Epidemiology Biomarkers and Prevention, 30(1), 217-228. [More Information]
- Madut, A., Fuchsova, V., Man, H., Askar, S., Trivedi, R., Elder, E., Clarke, C., Wain, G., Brand, A., deFazio, A., Amis, T., Kairaitis, K. (2021). Increased prevalence of obstructive sleep apnea in women diagnosed with endometrial or breast cancer. PloS One, 16(4), e0249658-1-e0249658-16. [More Information]
- Trivedi, R., Man, H., Madut, A., Mather, M., Elder, E., Dhillon, H., Brand, A., Howle, J., Mann, G., deFazio, A., Amis, T., Phillips, A., Kairaitis, K., et al (2021). Irregular Sleep/Wake Patterns Are Associated With Reduced Quality of Life in Post-treatment Cancer Patients: A Study Across Three Cancer Cohorts. Frontiers in Neuroscience, 15, 700923. [More Information]
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2020
- Schofield, P., Gough, K., Pascoe, M., Bergin, R., White, K., Mileshkin, L., Bernshaw, D., Kinnane, N., Jackson, M., Do, V., Juraskova, I., et al (2020). A nurse- and peer-led psycho-educational intervention to support women with gynaecological cancers receiving curative radiotherapy: The PeNTAGOn randomised controlled trial – ANZGOG 1102. Gynecologic Oncology, 159(3), 785-793. [More Information]
- Heriot, N., Brand, A., Cohen, P., Hegarty, S., Hyde, S., Leung, Y., Zalcberg, J., Rome, R. (2020). Developing an Australian multi-module clinical quality registry for gynaecological cancers: A protocol paper. BMJ Open, 10(2), e034579. [More Information]
- Talhouk, A., George, J., Wang, C., Budden, T., Tan, T., Chiu, D., Kommoss, S., Leong, H., Chen, S., Intermaggio, M., Chiew, Y., Sharma, R., Nevins, N., deFazio, A., et al (2020). Development and validation of the gene expression predictor of high-grade serous ovarian carcinoma molecular SubTYPE (PrOTYPE). Clinical Cancer Research, 26(20), 5411-5423. [More Information]
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2019
- Sykes, P., Eva, L., Van Der Griend, R., McNally, O., Blomfield, P., Brand, A., Tristram, A., Bergzoll, C., Petrich, S., Kenwright, D., et al (2019). Pathological process has a crucial role in sentinel node biopsy for vulvar cancer. Gynecologic Oncology, 153(2), 292-296. [More Information]
- Velentzis, L., Smith, M., Simms, K., Lew, J., Hall, M., Hughes, S., Yuill, S., Killen, J., Keane, A., Butler, K., Skinner, R., Brand, A., Bateson, D., Armstrong, B., Canfell, K., et al (2019). Pathways to a cancer-free future: A protocol for modelled evaluations to maximize the future impact of interventions on cervical cancer in Australia. Gynecologic Oncology, 152(3), 465-471. [More Information]
- Cheasley, D., Wakefield, M., Ryland, G., Allan, P., Alsop, K., Amarasinghe, K., Ananda, S., Anglesio, M., Au-Yeung, G., Bohm, M., Brand, A., Chiew, Y., deFazio, A., Kennedy, C., Sharma, R., et al (2019). The molecular origin and taxonomy of mucinous ovarian carcinoma. Nature Communications, 10(1), 1-11. [More Information]
2018
- Garsed, D., Alsop, K., Fereday, S., Emmanuel, C., Kennedy, C., Etemadmoghadam, D., Gao, B., Gebski, V., Gares, V., Christie, E., Sharma, R., Brand, A., Harnett, P., deFazio, A., et al (2018). Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer. Clinical Cancer Research, 24(3), 569-580. [More Information]
- Farrell, R., Liauw, W., Brand, A. (2018). Ovarian Cancer Surgery in Australia and New Zealand: A Survey to Determine Changes in Surgical Practice Over 10 Years. International Journal of Gynecological Cancer, 28(5), 945-950. [More Information]
- Jamieson, A., Brand, A. (2018). Response to: Cervical cancer in women under 25 years of age in Queensland, Australia: To what extent is the diagnosis made by screening cytology? Australian and New Zealand Journal of Obstetrics and Gynaecology, 58(3), E5-E6. [More Information]
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2017
- Brand, A., DiSilvestro, P., Sehouli, J., Berek, J. (2017). Cytoreductive surgery for ovarian cancer: quality assessment. Annals of Oncology, 28(Suppl 8), viii25-viii29. [More Information]
- Janda, M., Gebski, V., Davies, L., Forder, P., Brand, A., Hogg, R., Jobling, T., Land, R., Manolitsas, T., Nascimento, M., et al (2017). Effect of total laparoscopic hysterectomy vs total abdominal hysterectomy on disease-free survival among women with stage i endometrial cancer: A randomized clinical trial. JAMA - Journal of the American Medical Association, 317(12), 1224-1233. [More Information]
- Lindemann, K., Kok, P., Stockler, M., Jaaback, K., Brand, A. (2017). Enhanced recovery after surgery for advanced ovarian cancer: A systematic review of interventions trialed. International Journal of Gynecological Cancer, 27(6), 1274-1282. [More Information]
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2016
- Anuradha, S., Donovan, P., Webb, P., Brand, A., Goh, J., Friedlander, M., Oehler, M., Quinn, M., Steer, C., Jordan, S. (2016). Variations in adjuvant chemotherapy and survival in women with epithelial ovarian cancer - a population-based study. Acta Oncologica, 55(2), 226-233. [More Information]
2015
- Brand, A., Harrison, A., Kumar, K. (2015). "It was definitely very different": An evaluation of palliative care teaching to medical students using a mixed methods approach. Journal of Palliative Care, 31(1), 21-28. [More Information]
- Webb, P., deFazio, A., Protani, M., Ibiebele, T., Nagle, C., Brand, A., Blomfield, P., Grant, P., Perrin, L., Neale, R. (2015). Circulating 25-hydroxyvitamin D and survival in women with ovarian cancer. American Journal of Clinical Nutrition, 102(1), 109-114. [More Information]
- Beesley, V., Rowlands, I., Hayes, S., Janda, M., O'Rourke, P., Marquart, L., Quinn, M., Spurdle, A., Obermair, A., Brand, A., et al (2015). Incidence, risk factors and estimates of a woman's risk of developing secondary lower limb lymphedema and lymphedema-specific supportive care needs in women treated for endometrial cancer. Gynecologic Oncology, 136(1), 87-93. [More Information]
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2014
- Emmanuel, C., Chiew, Y., George, J., Etemadmoghadam, D., Anglesio, M., Sharma, R., Russell, P., Kennedy, C., Fereday, S., Hung, J., Hogg, R., Wain, G., Brand, A., Balleine, R., Clarke, C., Harnett, P., deFazio, A., et al (2014). Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver. Clinical Cancer Research, 20(24), 6618-6630. [More Information]
- Rowlands, I., Beesley, V., Janda, M., Hayes, S., Obermair, A., Quinn, M., Brand, A., Leung, Y., McQuire, L., Webb, P. (2014). Quality of life of women with lower limb swelling or lymphedema 3-5years following endometrial cancer. Gynecologic Oncology, 133(2), 314-318. [More Information]
- Anuradha, S., Webb, P., Blomfield, P., Brand, A., Friedlander, M., Leung, Y., Obermair, A., Oehler, M., Quinn, M., Steer, C., et al (2014). Survival of Australian women with invasive epithelial ovarian cancer: a population-based study. Medical Journal of Australia, 201(5), 283-288. [More Information]
2013
- Brand, A., King, M. (2013). Does Extensive Upper Abdomen Surgery During Primary Cytoreduction Impact on Long-term Quality of Life? Baseline Plus Longitudinal Quality-of-Life Assessment Would Have Provided a Better Answer. International Journal of Gynecological Cancer, 23(6), 980-981. [More Information]
- Blinman, P., Gainford, C., Donoghoe, M., Martyn, J., Bloomfield, P., Grant, P., Kichenadasse, G., Vaughan, M., Brand, A., Shannon, C., Gebski, V., Stockler, M., et al (2013). Feasibility, acceptability and preferences for intraperitoneal chemotherapy with paclitaxel and cisplatin after optimal debulking surgery for ovarian and related cancers: an ANZGOG study. Journal of Gynecologic Oncology, 24(4), 359-366. [More Information]
2012
- Brand, A., Do, V., Stenlake, A. (2012). Can an Educational Intervention Improve Compliance With Vaginal Dilator Use in Patients Treated With Radiation for a Gynecological Malignancy? International Journal of Gynecological Cancer, 22(5), 897-904. [More Information]
- Sidhu, V., Lancaster, L., Elliott, D., Brand, A. (2012). Implementation and audit of 'Fast-Track Surgery' in gynaecological oncology surgery. Australian and New Zealand Journal of Obstetrics and Gynaecology, 52(4), 371-376. [More Information]
- Obermair, A., Janda, M., Baker, J., Kondalsamy-Chennakesavan, S., Brand, A., Hogg, R., Jobling, T., Land, R., Manolitsas, T., Nascimento, M., Gebski, V., et al (2012). Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(8), 1147-1153. [More Information]
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2011
- Emmanuel, C., Gava, N., Kennedy, C., Balleine, R., Sharma, R., Wain, G., Brand, A., Hogg, R., Etemadmoghadam, D., George, J., Clarke, C., Harnett, P., deFazio, A., et al (2011). Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis. PloS One, 6(3), e17617-1-e17617-18. [More Information]
- Brand, A. (2011). Ovarian Cancer Debulking Surgery: A Survey of Practice in Australia and New Zealand. International Journal of Gynecological Cancer, 21(2), 230-235. [More Information]
- Brand, A. (2011). The RANZCOG College Statement on prophylactic oophorectomy in older women undergoing hysterectomy for benign disease: Is the evidence sufficient to change practice? Australian and New Zealand Journal of Obstetrics and Gynaecology, 51(4), 296-300. [More Information]
2010
- Janda, M., Gebski, V., Brand, A., Hogg, R., Jobling, T., Land, R., Manolitsas, T., McCartney, A., Nascimento, M., Neesham, D., Pather, S., et al (2010). Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial. The Lancet Oncology, 11(8), 772-780. [More Information]
2009
- Bunting, M., Chan, W., Brand, A., Blomfield, P. (2009). Intraperitoneal chemotherapy for advanced epithelial ovarian malignancy: Lessons learned. Australian and New Zealand Journal of Obstetrics and Gynaecology, 49(6), 667-671. [More Information]
- Wang, W., Do, V., Hogg, R., Wain, G., Brand, A., Bull, C., Stenlake, A., Gebski, V. (2009). Uterine papillary serous carcinoma: patterns of failure and survival. Australian and New Zealand Journal of Obstetrics and Gynaecology, 49(4), 419-425. [More Information]
2008
- Scurr, L., Guminski, A., Chiew, Y., Balleine, R., Sharma, R., Lei, Y., Pryor, K., Wain, G., Brand, A., Byth, K., Kennedy, C., Rizos, H., Harnett, P., deFazio, A. (2008). Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer. Clinical Cancer Research, 14(21), 6924-6932. [More Information]
2007
- Brand, A. (2007). The woman with postmenopausal bleeding. Australian Family Physician, 36(3), 116-120. [More Information]
2006
- Hodgkinson, K., Butow, P., Fuchs, A., Hunt, G., Stenlake, A., Hobbs, K., Brand, A., Wain, G. (2006). Long-term survival from gynecologic cancer: Psychosocial outcomes, supportive care needs and positive outcomes. Gynecologic Oncology, 104(2), 381-389. [More Information]
- Brand, A., Bull, C., Cakir, B. (2006). Vaginal stenosis in patients treated with radiotherapy for carcinoma of the cervix. International Journal of Gynecological Cancer, 16(1), 288-293. [More Information]
Selected Grants
2019
- INOVATe 2.0 Individualised Ovarian Cancer Treatment Through Integration of Genomic Pathology into Multidisciplinary Care - Phase 2: Evaluation, Implementation and Integration into Clinical Practice, deFazio A, Harnett P, Friedlander M, Balleine R, Harnett P, Bowtell D, Marsh D, Samimi G, Brand A, Marsh D, Beale P, Friedlander M, Anderson L, Cancer Council NSW/Translational Program Grant
- The ECHO trial: Exercise during Chemotherapy for Ovarian Cancer, Hayes S, Mileshkin L, Brand A, Barnes E, Cancer Australia/Priority Driven Collaborative Cancer Research Scheme
2017
- Obstructive sleep apnoea in cancer cohorts: interactions with cancer biology, French J, Kairaitis K, Amis T, deFazio A, Brand A, Mann G, Howle J, Carlino M, Wong E, Clarke C, Elder E, ResMed Foundation/Research Grant
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Collaboration Group Publications
- Kang, E., Cheasley, D., LePage, C., Wakefield, M., da Cunha Torres, M., Rowley, S., Salazar, C., Xing, Z., Allan, P., Bowtell, D., Kennedy, C., deFazio, A., GAMuT Collaborators., et al (2021). Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses. Modern Pathology, 34(1), 194-206. [More Information]
Additional Grants
2020
- Ovarian cancer: investigating Variation in care and survival, Aetiology and Risk factors to Improve outcomes in Australia via National data linkage: the OVARIAN study, Webb P, Brand A(AI), MRFF, Ovarian Cancer Research Grant