People_
Dr Amanda Hudson
Sydney Vital Fellow
Bill Walsh Translational Cancer Research Laboratory, Kolling Institute
Northern Sydney Local Health District
Sydney Medical School Northern
University of Sydney
Bill Walsh Translational Cancer Research Laboratory, Kolling Institute
Northern Sydney Local Health District
Sydney Medical School Northern
University of Sydney
Publications
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Journals
- Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
- Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]
- Colvin, E., Hudson, A., Anderson, L., Kumar, R., McGregor, I., Howell, V., Arnold, J. (2022). An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma. Cancers, 14(15). [More Information]
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2023
- Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
- Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]
2022
- Colvin, E., Hudson, A., Anderson, L., Kumar, R., McGregor, I., Howell, V., Arnold, J. (2022). An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma. Cancers, 14(15). [More Information]
- McKelvey, K., Hudson, A., Donaghy, H., Stoner, S., Wheeler, H., Diakos, C., Howell, V. (2022). Differential effects of radiation fractionation regimens on glioblastoma. Radiation Oncology, 17(1), 17-1-17-14. [More Information]
2021
- Prashanth, A., Donaghy, H., Stoner, S., Hudson, A., Wheeler, H., Diakos, C., Howell, V., Grau, G., McKelvey, K. (2021). Are In Vitro Human Blood-Brain-Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics? Cancers, 13(5), 955-1-955-19. [More Information]
- Sahin, K., Shah, E., Ferguson, G., Molloy, C., Kalita, P., Hayes, S., Hudson, A., Colvin, E., Kamitakahara, H., Harvie, R., Hasovits, C., Howell, V., et al (2021). Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer. Cancers, 13(18), 4651. [More Information]
2020
- Itchins, M., Lau, B., Hudson, A., Westman, H., Xia, C., Hayes, S., Howell, V., Rodriguez, M., Cooper, W., Wei, G., Buckland, M., Li, B., Gill, A., Clarke, S., Pavlakis, N., et al (2020). ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 25(8), 641-649. [More Information]
- Anderson, K., Tan, A., Parkinson, J., Back, M., Kastelan, M., Newey, A., Brewer, J., Wheeler, H., Hudson, A., Amin, S., Khasraw, M., et al (2020). Molecular and clonal evolution in recurrent metastatic gliosarcoma. Cold Spring Harbor Molecular Case Studies, 6(1), 1-15. [More Information]
- McKelvey, K., Hudson, A., Kumar, R., Eade, T., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Sub-acute Toxicity in Non-cancerous Tissue and Immune-Related Adverse Events of a Novel Combination Therapy for Cancer. Frontiers in Oncology, 9, 1504. [More Information]
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2018
- Rath, E., Cheng, Y., Pinese, M., Sarun, K., Hudson, A., Weir, C., Wang, Y., Hakansson, A., Howell, V., Liu, G., Reid, G., Church, W., et al (2018). BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state. PloS One, 13(8), 1-32. [More Information]
- Hudson, A., Parker, N., Khong, P., Parkinson, J., Dwight, T., Ikin, R., Zhu, Y., Chen, J., Wheeler, H., Howell, V. (2018). Glioblastoma recurrence correlates with increased APE1 and polarization toward an immuno-suppressive microenvironment. Frontiers in Oncology, 8(AUG), 1-10. [More Information]
- McKelvey, K., Hudson, A., Back, M., Eade, T., Diakos, C. (2018). Radiation, inflammation and the immune response in cancer. Mammalian Genome, 29, 843-865. [More Information]
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2016
- Parker, N., Hudson, A., Khong, P., Parkinson, J., Dwight, T., Ikin, R., Zhu, Y., Cheng, Z., Vafaee, F., Chen, J., Wheeler, H., Howell, V. (2016). Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma. Scientific Reports, 6, 1-10. [More Information]
- Hudson, A., Colvin, E. (2016). Transgenic mouse models of SV40-induced cancer. ILAR Journal, 57(1), 44-54. [More Information]
2015
- Davis, I., Long, A., Yip, S., Espinoza, D., Thompson, J., Kichenadasse, G., Harrision, M., Lowenthal, R., Pavlakis, N., Azad, A., Hudson, A., Stockler, M., Martin, A., et al (2015). EVERSUN: A phase 2 trial of alternating sunitinib and everolimus as first line therapy for advanced renal cell carcinoma. Annals of Oncology, 26(6), 1118-1123. [More Information]
- Weir, C., Hudson, A., Peters, L., Howell, V. (2015). Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model. Journal of Visualized Experiments, 104, 1-12. [More Information]
- Ashton, A., Le, T., Gomez-Sanchez, C., Morel-Kopp, M., McWhitney, B., Hudson, A., Mihailidou, A. (2015). Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury. Molecular Endocrinology, 29(8), 1144-1155. [More Information]
2014
- Hudson, A., Weir, C., Moon, E., Harvie, R., Klebe, S., Clarke, S., Pavlakis, N., Howell, V. (2014). Establishing a panel of chemo-resistant mesothelioma models for investigating chemo-resistance and identifying new treatments for mesothelioma. Scientific Reports, 4, 1-11. [More Information]
- Hayes, S., Hudson, A., Clarke, S., Molloy, M., Howell, V. (2014). From mice to men: GEMMs as trial patients for new NSCLC therapies. Seminars in Cell & Developmental Biology, 27, 118-127. [More Information]
- Weir, C., Hudson, A., Moon, E., Ross, A., Alexander, M., Peters, L., Langova, V., Clarke, S., Pavlakis, N., Davey, R., Howell, V. (2014). Streptavidin: a novel immunostimulant for the selection and delivery of autologous and syngeneic tumor vaccines. Cancer Immunology Research, 2(5), 469-479. [More Information]
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Selected Grants
2019
- Modulating the inflammatory responses to improve treatment efficacy in brain cancer, Hudson A, Sydney Vital Translational Cancer Research/Flagship 1 Fellowship
- Elispot Reader for Monitoring the immune response in brain cancer patients, Hudson A, Howell V, McKelvey K, Brain Cancer Group Limited/Research Grant
2018
- Hypoxia: a therapeutic target for treatment-resistant brain cancer, Hudson A, Howell V, Mark Hughes Foundation Ltd/The Sutton Family Brain Cancer Research Project Grant
- The immuno-coagulome: an untapped pathway for new therapeutics in glioma, Hudson A, Howell V, McKelvey K, Brain Cancer Group Limited/Research Grant
- Brain Cancer Pre-clinical pipeline for Advancing Cancer Therapeutics Brain Cancer PACT, Hudson A, Howell V, McKelvey K, Mark Hughes Foundation Ltd/Project Grant
- Inflammation in Brain cancer, Howell V, Hudson A, McKelvey K, Diakos C, Brain Cancer Group Limited/Research Grant
- INTEGRATE. A Randomised Phase II Double-Blind Placebo-Controlled Study of regorafenib in Refractory Advanced Oesophago-Gastric Cancer AOGC. Protocol Number AG0212OG, Hudson A, Pavlakis N, National Health and Medical Research Council Clinical Trials Centre (NHMRC)/Research Support
- Combination therapy to combat cancer, McKelvey K, Howell V, Biggs M, Kamitakahara H, Colvin E, Hudson A, Mark Hughes Foundation Ltd/Hunter Medical Research Institute Fellowship
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