Dr Amanda Hudson
People_

Dr Amanda Hudson

Sydney Vital Fellow
Bill Walsh Translational Cancer Research Laboratory, Kolling Institute
Northern Sydney Local Health District
Sydney Medical School Northern
University of Sydney
Phone
+61 2 9926 4722
Fax
+61 2 9926 4035

Publications

Journals

  • Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
  • Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]
  • Colvin, E., Hudson, A., Anderson, L., Kumar, R., McGregor, I., Howell, V., Arnold, J. (2022). An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma. Cancers, 14(15). [More Information]

2023

  • Yuile, A., Satgunaseelan, L., Wei, J., Rodriguez, M., Back, M., Pavlakis, N., Hudson, A., Kastelan, M., Wheeler, H., Lee, A. (2023). CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Current Issues in Molecular Biology (Print), 45(7), 5276-5292. [More Information]
  • Maloney, S., Pavlakis, N., Itchins, M., Arena, J., Mittal, A., Hudson, A., Colvin, E., Sahni, S., Diakos, C., Chan, D., Gill, A., Samra, J., Clarke, S. (2023). The Prognostic and Predictive Role of the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR) as Biomarkers in Resected Pancreatic Cancer. Journal of Clinical Medicine, 12(5). [More Information]

2022

  • Colvin, E., Hudson, A., Anderson, L., Kumar, R., McGregor, I., Howell, V., Arnold, J. (2022). An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma. Cancers, 14(15). [More Information]
  • McKelvey, K., Hudson, A., Donaghy, H., Stoner, S., Wheeler, H., Diakos, C., Howell, V. (2022). Differential effects of radiation fractionation regimens on glioblastoma. Radiation Oncology, 17(1), 17-1-17-14. [More Information]

2021

  • Prashanth, A., Donaghy, H., Stoner, S., Hudson, A., Wheeler, H., Diakos, C., Howell, V., Grau, G., McKelvey, K. (2021). Are In Vitro Human Blood-Brain-Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics? Cancers, 13(5), 955-1-955-19. [More Information]
  • Sahin, K., Shah, E., Ferguson, G., Molloy, C., Kalita, P., Hayes, S., Hudson, A., Colvin, E., Kamitakahara, H., Harvie, R., Hasovits, C., Howell, V., et al (2021). Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer. Cancers, 13(18), 4651. [More Information]

2020

  • Itchins, M., Lau, B., Hudson, A., Westman, H., Xia, C., Hayes, S., Howell, V., Rodriguez, M., Cooper, W., Wei, G., Buckland, M., Li, B., Gill, A., Clarke, S., Pavlakis, N., et al (2020). ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 25(8), 641-649. [More Information]
  • Anderson, K., Tan, A., Parkinson, J., Back, M., Kastelan, M., Newey, A., Brewer, J., Wheeler, H., Hudson, A., Amin, S., Khasraw, M., et al (2020). Molecular and clonal evolution in recurrent metastatic gliosarcoma. Cold Spring Harbor Molecular Case Studies, 6(1), 1-15. [More Information]
  • McKelvey, K., Hudson, A., Kumar, R., Eade, T., Clarke, S., Wheeler, H., Diakos, C., Howell, V. (2020). Sub-acute Toxicity in Non-cancerous Tissue and Immune-Related Adverse Events of a Novel Combination Therapy for Cancer. Frontiers in Oncology, 9, 1504. [More Information]

2018

  • Rath, E., Cheng, Y., Pinese, M., Sarun, K., Hudson, A., Weir, C., Wang, Y., Hakansson, A., Howell, V., Liu, G., Reid, G., Church, W., et al (2018). BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state. PloS One, 13(8), 1-32. [More Information]
  • Hudson, A., Parker, N., Khong, P., Parkinson, J., Dwight, T., Ikin, R., Zhu, Y., Chen, J., Wheeler, H., Howell, V. (2018). Glioblastoma recurrence correlates with increased APE1 and polarization toward an immuno-suppressive microenvironment. Frontiers in Oncology, 8(AUG), 1-10. [More Information]
  • McKelvey, K., Hudson, A., Back, M., Eade, T., Diakos, C. (2018). Radiation, inflammation and the immune response in cancer. Mammalian Genome, 29, 843-865. [More Information]

2016

  • Parker, N., Hudson, A., Khong, P., Parkinson, J., Dwight, T., Ikin, R., Zhu, Y., Cheng, Z., Vafaee, F., Chen, J., Wheeler, H., Howell, V. (2016). Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma. Scientific Reports, 6, 1-10. [More Information]
  • Hudson, A., Colvin, E. (2016). Transgenic mouse models of SV40-induced cancer. ILAR Journal, 57(1), 44-54. [More Information]

2015

  • Davis, I., Long, A., Yip, S., Espinoza, D., Thompson, J., Kichenadasse, G., Harrision, M., Lowenthal, R., Pavlakis, N., Azad, A., Hudson, A., Stockler, M., Martin, A., et al (2015). EVERSUN: A phase 2 trial of alternating sunitinib and everolimus as first line therapy for advanced renal cell carcinoma. Annals of Oncology, 26(6), 1118-1123. [More Information]
  • Weir, C., Hudson, A., Peters, L., Howell, V. (2015). Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model. Journal of Visualized Experiments, 104, 1-12. [More Information]
  • Ashton, A., Le, T., Gomez-Sanchez, C., Morel-Kopp, M., McWhitney, B., Hudson, A., Mihailidou, A. (2015). Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury. Molecular Endocrinology, 29(8), 1144-1155. [More Information]

2014

  • Hudson, A., Weir, C., Moon, E., Harvie, R., Klebe, S., Clarke, S., Pavlakis, N., Howell, V. (2014). Establishing a panel of chemo-resistant mesothelioma models for investigating chemo-resistance and identifying new treatments for mesothelioma. Scientific Reports, 4, 1-11. [More Information]
  • Hayes, S., Hudson, A., Clarke, S., Molloy, M., Howell, V. (2014). From mice to men: GEMMs as trial patients for new NSCLC therapies. Seminars in Cell & Developmental Biology, 27, 118-127. [More Information]
  • Weir, C., Hudson, A., Moon, E., Ross, A., Alexander, M., Peters, L., Langova, V., Clarke, S., Pavlakis, N., Davey, R., Howell, V. (2014). Streptavidin: a novel immunostimulant for the selection and delivery of autologous and syngeneic tumor vaccines. Cancer Immunology Research, 2(5), 469-479. [More Information]

Selected Grants

2019

  • Modulating the inflammatory responses to improve treatment efficacy in brain cancer, Hudson A, Sydney Vital Translational Cancer Research/Flagship 1 Fellowship
  • Elispot Reader for Monitoring the immune response in brain cancer patients, Hudson A, Howell V, McKelvey K, Brain Cancer Group Limited/Research Grant

2018

  • Hypoxia: a therapeutic target for treatment-resistant brain cancer, Hudson A, Howell V, Mark Hughes Foundation Ltd/The Sutton Family Brain Cancer Research Project Grant
  • The immuno-coagulome: an untapped pathway for new therapeutics in glioma, Hudson A, Howell V, McKelvey K, Brain Cancer Group Limited/Research Grant
  • Brain Cancer Pre-clinical pipeline for Advancing Cancer Therapeutics Brain Cancer PACT, Hudson A, Howell V, McKelvey K, Mark Hughes Foundation Ltd/Project Grant
  • Inflammation in Brain cancer, Howell V, Hudson A, McKelvey K, Diakos C, Brain Cancer Group Limited/Research Grant
  • INTEGRATE. A Randomised Phase II Double-Blind Placebo-Controlled Study of regorafenib in Refractory Advanced Oesophago-Gastric Cancer AOGC. Protocol Number AG0212OG, Hudson A, Pavlakis N, National Health and Medical Research Council Clinical Trials Centre (NHMRC)/Research Support
  • Combination therapy to combat cancer, McKelvey K, Howell V, Biggs M, Kamitakahara H, Colvin E, Hudson A, Mark Hughes Foundation Ltd/Hunter Medical Research Institute Fellowship