Associate Professor Angela Chou
Northern Clinical School
A/Prof Angela Chou is a surgical pathologist at the Royal North Shore Hospital. She is also a translational researcher at the Kolling Institute with the Cancer Diagnosis and Pathology Group. She is actively involved in all aspects of research in all gastrointestinal cancers and endocrine tumours. She also has a special interest in renal tranplant pathology and collaborates with the RNSH renal transplant team on using molecular diagnostics to improve clinical outcome.
Translational cancer research, cancer biomarker discovery, cancer genomics, cancer pathology. Renal pathology, renal tranplant, acute transplant rejection. Molecular diagnostics.
2020 Cancer Institute of NSW Outstanding Cancer Research Fellow – Early Career Fellow Award
2019 Cancer Institute of NSW The Wild Fire Award (Group Award)
2018 Cancer Institute of NSW The Wild Fire Award (Group Award)
2017 - 2019 Cancer Institute of NSW Early Career Fellowship
2015 Cancer Institute of NSW The “Rising Star” PhD student award
2015 Cancer Institute of NSW The Wild Fire Award (Group Award)
2014 - 2015 Sydney Catalyst Top-up Research Scholar Award
2013 Castle Harlan Award
2013 St Vincent’s Clinic Foundation Annual Grant
2013 to 2016 NHMRC Postgraduate Scholarship APP1039812
2013 International Academy of Pathologists, Australasia Division Meeting Best Poster Award. (Dr Chou first author)
2012 Cancer Institute of NSW Wildfire Award (Group Award)
2012 Royal College of Pathologists Australasia, Research Award
2011 SYDPATH Grant, St Vincent’s Hospital
(THE INTERNATIONAL STUDY GROUP ON NON-PANCREATIC PERIAMPULLARY CANCER) PERIPAN 2023 International Consensus meeting https://isgaca.com/peripan-2/ |
Publications
Journals
- Janssen, B., Doukas, M., Drillenburg, P., Esposito, I., Gill, A., Hong, S., Jansen, C., Kliffen, M., Mittal, A., Samra, J., Chou, A., et al (2024). Artificial Intelligence-based Segmentation of Residual Pancreatic Cancer in Resection Specimens Following Neoadjuvant Treatment (ISGPP-2) International Improvement and Validation Study. American Journal of Surgical Pathology. [More Information]
- Aksoy, Y., Chou, A., Clarkson, A., Clifton-Bligh, R., De Leo, A., Dogan, S., Ganly, I., Ghossein, R., Gild, M., Glover, A., Papachristos, A., Robinson, B., Sidhu, S., Sywak, M., Tsang, V., Turchini, J., Gill, A., Fuchs, T., Seyed Ahadi, M., et al (2024). Novel prognostic nomogram for predicting recurrence-free survival in medullary thyroid carcinoma. Histopathology, 84(6), 947-959. [More Information]
- Turchini, J., Sidhu, S., Gill, A., Fuchs, T., Chou, A., Sioson, L., Clarkson, A., Sheen, A., Delbridge, L., Glover, A., Sywak, M. (2023). A Critical Assessment of Diagnostic Criteria for the Tall Cell Subtype of Papillary Thyroid Carcinoma—How Much? How Tall? And When Is It Relevant? Endocrine Pathology, 34(4), 461-470. [More Information]
2024
- Janssen, B., Doukas, M., Drillenburg, P., Esposito, I., Gill, A., Hong, S., Jansen, C., Kliffen, M., Mittal, A., Samra, J., Chou, A., et al (2024). Artificial Intelligence-based Segmentation of Residual Pancreatic Cancer in Resection Specimens Following Neoadjuvant Treatment (ISGPP-2) International Improvement and Validation Study. American Journal of Surgical Pathology. [More Information]
- Aksoy, Y., Chou, A., Clarkson, A., Clifton-Bligh, R., De Leo, A., Dogan, S., Ganly, I., Ghossein, R., Gild, M., Glover, A., Papachristos, A., Robinson, B., Sidhu, S., Sywak, M., Tsang, V., Turchini, J., Gill, A., Fuchs, T., Seyed Ahadi, M., et al (2024). Novel prognostic nomogram for predicting recurrence-free survival in medullary thyroid carcinoma. Histopathology, 84(6), 947-959. [More Information]
2023
- Turchini, J., Sidhu, S., Gill, A., Fuchs, T., Chou, A., Sioson, L., Clarkson, A., Sheen, A., Delbridge, L., Glover, A., Sywak, M. (2023). A Critical Assessment of Diagnostic Criteria for the Tall Cell Subtype of Papillary Thyroid Carcinoma—How Much? How Tall? And When Is It Relevant? Endocrine Pathology, 34(4), 461-470. [More Information]
- Xu, B., Chau, N., Chiarucci, F., Chou, A., Clifton-Bligh, R., Coluccelli, S., de Biase, D., De Leo, A., Dogan, S., Fagin, J., Fuchs, T., Glover, A., Luxford, C., Seyed Ahadi, M., Papachristos, A., Robinson, B., Sidhu, S., Sywak, M., Gill, A., et al (2023). Association of the Genomic Profile of Medullary Thyroid Carcinoma with Tumor Characteristics and Clinical Outcomes in an International Multicenter Study. Thyroid. [More Information]
- Tran, K., Prall, O., Mitchell, C., Chou, A., Gill, A., Grimmond, S., Kong, G., Kiernan, G., Torche, C., Lipton, L., et al (2023). Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature. Current Problems in Cancer: Case Reports, 9. [More Information]
2022
- Fuchs, T., Chou, A., Aksoy, Y., Mahjoub, M., Sheen, A., Sioson, L., Seyed Ahadi, M., Gill, A. (2022). A Critical Assessment of Current Grading Schemes for Diffuse Pleural Mesothelioma With a Proposal for a Novel Mesothelioma Weighted Grading Scheme (MWGS). American Journal of Surgical Pathology, 46(6), 774-785. [More Information]
- Meagher, N., Gorringe, K., Wakefield, M., Bolithon, A., Pang, C., Chiu, D., Anglesio, M., Mallitt, K., Doherty, J., Harris, H., Chou, A., Gill, A., Ward, R., Anderson, L., deFazio, A., et al (2022). Gene expression profiling of mucinous ovarian tumors and comparison with upper and lower astrointestinal tumors identifies markers associated with adverse outcomes. Clinical Cancer Research, 28(24), 5383-5395. [More Information]
- Janssen, B., van Roessel, S., van Dieren, S., de Boer, O., Adsay, V., Basturk, O., Brosens, L., Campbell, F., Chatterjee, D., Chou, A., Fuchs, T., Gill, A., et al (2022). Histopathological tumour response scoring in resected pancreatic cancer following neoadjuvant therapy: international interobserver study (ISGPP-1). British Journal of Surgery, 110(1), 67-75. [More Information]
2021
- Sharbeen, G., McCarroll, J., Akerman, A., Kopecky, C., Youkhana, J., Kokkinos, J., Holst, J., Boyer, C., Erkan, M., Goldstein, D., Chou, A., Gill, A., Gebski, V., et al (2021). Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition. Cancer Research, 81(13), 3461-3479. [More Information]
- Nguyen, L., Saad, S., Shi, Y., Wang, R., Chou, A., Gill, A., Yao, Y., Jarolimek, W., Pollock, C. (2021). Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse. Scientific Reports, 11(1), 12437. [More Information]
- Seyed Ahadi, M., Sokolova, A., Brown, I., Chou, A., Gill, A. (2021). The 2019 World Health Organization Classification of appendiceal, colorectal and anal canal tumours: an update and critical assessment. Pathology, 53(4), 454-461. [More Information]
2020
- Fuchs, T., Sioson, L., Sheen, A., Jafari-Nejad, K., Renaud, C., Andrici, J., Seyed Ahadi, M., Chou, A., Gill, A. (2020). Assessment of Tumor-infiltrating Lymphocytes Using International TILs Working Group (ITWG) System Is a Strong Predictor of Overall Survival in Colorectal Carcinoma: A Study of 1034 Patients. The American Journal of Surgical Pathology, 44(4), 536-544. [More Information]
- Pulvers, J., Guminski, A., Chou, A., Gill, A., Seyed Ahadi, M. (2020). Decoding a mysterious morphology with molecular pathology: chondroid metaplasia in a metastatic gastrointestinal stromal tumour after imatinib therapy. Pathology, 52(3), 396-398. [More Information]
- Nylen, C., Mechera, R., Marechal-Ross, I., Tsang, V., Chou, A., Gill, A., Clifton-Bligh, R., Robinson, B., Sywak, M., Sidhu, S., Glover, A. (2020). Molecular Markers Guiding Thyroid Cancer Management. Cancers, 12(8), 1-26. [More Information]
2019
- Gill, A., Lim, G., Cheung, V., Andrici, J., Perry-Keene, J., Paik, J., Sioson, L., Clarkson, A., Sheen, A., Luxford, C., Engelsman, A., Sywak, M., Sidhu, S., Delbridge, L., Robinson, B., Marsh, D., Toon, C., Chou, A., Clifton-Bligh, R., et al (2019). Parafibromin-deficient (HPT-JT Type, CDC73 Mutated) Parathyroid Tumors Demonstrate Distinctive Morphologic Features. The American Journal of Surgical Pathology, 43(1), 35-46. [More Information]
- Fuchs, T., Bell, S., Gill, A., Chou, A. (2019). Revisiting the Significance of Prominent C Cells in the Thyroid. Endocrine Pathology, 30(2), 113-117. [More Information]
2018
- Chou, A., Itchins, M., De Reuver, P., Arena, J., Clarkson, A., Sheen, A., Sioson, L., Cheung, V., Perren, A., Nahm, C., Mittal, A., Samra, J., Gill, A., et al (2018). ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumours. Human Pathology, 82, 249-257. [More Information]
- Chou, A., Toon, C., Clarkson, A., Sheen, A., Sioson, L., Gill, A. (2018). The epithelioid, BAP1-negative and p16-positive phenotype predicts prolonged survival in pleural mesothelioma. Histopathology, 72(3), 509-515. [More Information]
- Parkin, A., Man, J., Chou, A., Nagrial, A., Samra, J., Gill, A., Timpson, P., Pajic, M. (2018). The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma. Diseases, 6(4), 1-18. [More Information]
Selected Grants
2020
- Biomarker-driven preclinical trial of pancreatic cancer defines a CDK4/6 inhibitor responsivemolecular subtype, Chou A, Cancer Institute NSW/NSW Premiers Awards for Outstanding Cancer Research