Dr Brent McParland
People_

Dr Brent McParland

Senior Lecturer
Sydney Pharmacy School
Phone
+61 2 9036 6477
Fax
+61 2 9351 4717
Details
Dr Brent McParland

Mechanisms that cause exaggerated narrowing of the airways in asthma and COPD.

Investigating whether Australian ticks cause Lyme disease (borreliosis)

Pharmacology Fundamentals (Basic Pharmacology)

Respiratory Diseases (Asthma, COPD, PAH) Autacoid Pharmacology (5HT, NO, Bradykinin, PGs, LTs, Histamine) Drugs in Sport

Obesity, Diabetes and Cardiovascular Disease, Infection and Immunological Conditions, Reproductive, Maternal and Child Health

Publications

Book Chapters

  • McParland, B., Seow, C., Pare, P., Macklem, P. (2005). Mechanics of Airway Narrowing. In Q. Hamid, J. Shannon, J. Martin (Eds.), Physiologic Basis of Respiratory Disease, (pp. 371-380). United States of America: BC Decker Inc.

Journals

  • Xu, J., Ghadiri, M., Svolos, M., McParland, B., Traini, D., Ong, H., Young, P. (2021). Investigating potential TRPV1 positive feedback to explain TRPV1 upregulation in airway disease states. Drug Development and Industrial Pharmacy, 47(12), 1924-1934. [More Information]
  • Storey-Lewis, B., Mitrovic, A., McParland, B. (2018). Molecular detection and characterisation of Babesia and Theileria in Australian hard ticks. Ticks and Tick-borne Diseases, 9(3), 471-478. [More Information]
  • Faiz, A., Donovan, C., Nieuwenhuis, M., Van Den Berge, M., Postma, D., Yao, S., Park, C., Hirsch, R., Fredberg, J., Tjin, G., Black, J., Oliver, B., McParland, B., Burgess, J., et al (2017). Latrophilin receptors: Novel bronchodilator targets in asthma. Thorax, 72(1), 74-82. [More Information]

2021

  • Xu, J., Ghadiri, M., Svolos, M., McParland, B., Traini, D., Ong, H., Young, P. (2021). Investigating potential TRPV1 positive feedback to explain TRPV1 upregulation in airway disease states. Drug Development and Industrial Pharmacy, 47(12), 1924-1934. [More Information]

2018

  • Storey-Lewis, B., Mitrovic, A., McParland, B. (2018). Molecular detection and characterisation of Babesia and Theileria in Australian hard ticks. Ticks and Tick-borne Diseases, 9(3), 471-478. [More Information]

2017

  • Faiz, A., Donovan, C., Nieuwenhuis, M., Van Den Berge, M., Postma, D., Yao, S., Park, C., Hirsch, R., Fredberg, J., Tjin, G., Black, J., Oliver, B., McParland, B., Burgess, J., et al (2017). Latrophilin receptors: Novel bronchodilator targets in asthma. Thorax, 72(1), 74-82. [More Information]

2013

  • Van Ly, D., Faiz, A., Jenkins, C., Crossett, B., Black, J., McParland, B., Burgess, J., Oliver, B. (2013). Characterising the Mechanism of Airway Smooth Muscle B2 Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells. PloS One, 8(2), 1-17. [More Information]

2012

  • Matthews, S., Succar, P., Jelinek, H., McParland, B., Buckland, M., McLachlan, C. (2012). Diagnosis of oligodendroglioma: Molecular and classical histological assessment in the twenty-first century. Asia-Pacific Journal of Clinical Oncology, 8(3), 213-216. [More Information]

2009

  • Cooper, P., McParland, B., Mitchell, H., Noble, P., Politi, A., Ressmeyer, A., West, A. (2009). Airway mechanics and methods used to visualize smooth muscle dynamics in vitro. Pulmonary Pharmacology and Therapeutics, 22(5), 398-406. [More Information]
  • Chapman, D., Berend, N., King, G., McParland, B., Salome, C. (2009). Deep inspirations protect against airway closure in nonasthmatic subjects. Journal of Applied Physiology, 107(2), 564-569. [More Information]
  • Trian, T., Qi, G., Moir, L., Burgess, J., Kuo, C., King, N., Reddel, H., Black, J., Oliver, B., McParland, B. (2009). Rhinovirus-induced Exacerbations of Asthma - How is the β2-adrenoceptor Implicated? American Journal of Respiratory Cell and Molecular Biology, 43(2), 227-233. [More Information]

2007

  • An, S., Bai, T., Bates, J., Black, J., Brown, R., Brusasco, V., Chitano, P., Deng, L., King, G., McParland, B., et al (2007). Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. European Respiratory Journal, 29(5), 834-860. [More Information]
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. Thorax, 62(10), 848-854. [More Information]
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by asthmatic and non-asthmatic airway smooth muscle cells. Thorax, 62(10), 848-854. [More Information]

2005

  • McParland, B., Seow, C., Pare, P., Macklem, P. (2005). Mechanics of Airway Narrowing. In Q. Hamid, J. Shannon, J. Martin (Eds.), Physiologic Basis of Respiratory Disease, (pp. 371-380). United States of America: BC Decker Inc.
  • McParland, B., Tait, R., Pare, P., Seow, C. (2005). The Role of Airway Smooth Muscle during an Attack of Asthma Simulated In Vitro. American Journal of Respiratory Cell and Molecular Biology, 33(5), 500-504. [More Information]
  • Herrera, A., McParland, B., Bienkowska, A., Tait, R., Pare, P., Seow, C. (2005). ‘Sarcomeres’ of smooth muscle: functional characteristics and ultrastructural evidence. Journal of Cell Science, 118(11), 2381-2392. [More Information]

2004

  • McParland, B., Pare, P., Johnson, P., Armour, C., Black, J. (2004). Airway Basement Membrane Perimeter In Human Airways Is Not A Constant; Potential Implications For Airway Remodeling In Asthma. Journal of Applied Physiology, 97(2), 556-563. [More Information]

2003

  • Burgess, J., Johnson, P., Ge, Q., Au, W., Poniris, M., McParland, B., King, G., Roth, M., Black, J. (2003). Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 167(1), 71-77. [More Information]

2002

  • Burgess, J., McParland, B. (2002). Analysis of gene expression. Methods in Enzymology, 356(22), 259-270. [More Information]
  • Ball, H., McParland, B., Driussi, C., Hunt, N. (2002). Isolating vessels from the mouse brain for gene expression analysis using laser capture microdissection. Brain Research Protocols, 9(3), 206-213. [More Information]

Selected Grants

2014

  • Australias Lyme-Like Illness: a focus on north-eastern NSW and south-eastern Queensland, Mitrovic A, McParland B, Australian Respiratory Council/Research Support

2013

  • Airway extracellular matrix and smooth muscle in chronic obstructive pulmonary disease (COPD), James A, King G, Noble P, McFawn P, McParland B, National Health and Medical Research Council (NHMRC)/Project Grants