People_

Dr Chang Lei

ARC DECRA Fellow
Department of Medical Sciences
Faculty of Medicine and Health

Phone

0293519872

Email

chang.lei@sydney.edu.au

Details

Member of The University of Sydney Nano Institute

Member of the Charles Perkins Centre

Websites

Google scholar

Biographical details

Dr Lei is an ARC Discovery Early Career Researcher Award (DECRA) fellow and a trained dentist with expertise in nanotechnology-based bioanalysis, mass spectrometry, lateral flow immunoassay, and tissue regeneration. She completed her PhD at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland (UQ). Shortly after her PhD, she received the Queensland Government Advance Queensland Research Fellowship to support her research on nanotechnology-enhanced bio-detection with an industry translational focus. She was then awarded the UQ Amplify Fellowship in 2021 and secured the prestigious ARC DECRA in 2024.

Current projects

Next Generation Mass Spectrometry for Single-Cell Metabolomics

Characterising metabolites at the single-cell level will provide valuable insights into the functionality of individual cells and reveal mechanisms that cannot be observed in bulk cell analysis. Mass spectrometry (MS) is a sensitive analytical technique that can measure chemical compounds and biological molecules, and it is widely used in diverse applications including biological research, drug testing, food contamination detection, and pesticide residue analysis. This project will develop a novel platform equipped with innovative nanomaterials featuring carefully designed nanostructures to enhance the sensitivity of MS, enabling high-quality single-cell metabolomics analysis.

A Nano-platform for Affordable and Ultra-sensitive Biomarker Detection

Biomolecules of clinical significance are often various forms of proteins or peptides present at very low concentrations in biological systems. Analysing these biomolecules is a significant challenge due to the complexity of bio-samples, yet it is essential for diagnosis and clinical applications. In this project, we focus on developing novel approaches for the sensitive detection of trace biomolecules using state-of-the-art nanotechnology. The project involves the preparation and characterisation of porous nanomaterials, biomolecule detection, and disease diagnosis.

Silica bio-nanomaterials assisted stem cell differentiation for bone repair

Bone defects, caused by infections, tumours, traumas, or congenial deformity, usually needs surgical interference and to be repaired with bone grafts or biomaterials. The traditional bone repair strategies usually have slow regeneration rate due to the poor cell adhesion and poor differentiation induction capacity of bone repair materials. This project aims to develop novel biomaterials to promote the differentiation of bone marrow stem cell for bone regeneration. Nanomaterials with functional compositions and porous nanostructures will be fabricated. Their cellular internalisation process and the resulted bone regeneration efficiency will be evaluated. On completion of this project, a next generation of biomaterial with high bone repair efficiency will be developed and the in-depth understanding on the interaction between nanomaterial and stem cell differentiation will be revealed.

Associations

Membership:

Member of The University of Sydney Nano Institute
Member of the Charles Perkins Centre
Member of Australian and New Zealand Society for Mass Spectrometry
Member of The Australian Materials Research Society
Member of the Australian Nanotechnology Network

Awards and honours

2024 ARC DECRA Fellow

2021 The University of QueenslandAmplify Fellow

2020 GC Minimum Intervention Dentistry Research Award

2017 Advanced Queensland Research Fellow

Keywords

Biochemistry, Dentistry, Biomedical engineering, Biological markers

Publications

By Type

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Book Chapters

Hosseinpour, S., Nanda, A., Lei, C., Lowe, B., Ye, Q., Xu, C. (2021). Nanobiomaterials in Craniofacial Bone Regeneration. In Ramesh S. Chaughule, Rajesh Dashaputra (Eds.), Advances in Dental Implantology using Nanomaterials and Allied Technology Applications, (pp. 25-52). Switzerland: Springer Nature Switzerland AG. [More Information]
Cheng, N., Wen, J., Hitching, R., Lei, C., Xu, C. (2021). Tooth bioengineering and whole tooth regeneration. In Sepanta Hosseinpour, Laurence J. Walsh (Eds.), Regenerative Approaches in Dentistry. An Evidence-Based Perspective, (pp. 89-102). Switzerland: Springer. [More Information]

Journals

Lei, C. (2023). Nanotechnology: Paving the way for advanced healthcare and beyond. Nano TransMed, 2, 100023. [More Information]
Li, Y., Xu, C., Lei, C. (2023). The Delivery and Activation of Growth Factors Using Nanomaterials for Bone Repair. Pharmaceutics, 15(3), 1017. [More Information]
Hosseinpour, S., Gomez-Cerezo, M., Cao, Y., Lei, C., Dai, H., Walsh, L., Ivanovski, S., Xu, C. (2022). A Comparative Study of Mesoporous Silica and Mesoporous Bioactive Glass Nanoparticles as Non-Viral MicroRNA Vectors for Osteogenesis. Pharmaceutics, 14(11), 2302. [More Information]
Xu, C., Lei, C., Wang, Y., Yu, C. (2022). Dendritic Mesoporous Nanoparticles: Structure, Synthesis and Properties. Angewandte Chemie - International Edition, 61(12), e202112752. [More Information]
Kong, Y., Tang, C., Lei, C., Nanjundan, A., Chen, S., Ahmed, N., Rakov, D., Du, A., Huang, X., Yu, C. (2022). Enabling two-electron redox chemistry of P-type organic cathode for high-capacity aluminium-ion batteries. Nano Energy, 102, 107727. [More Information]
Xu, C., Lei, C., Hosseinpour, S., Ivanovski, S., Walsh, L., Khademhosseini, A. (2022). Nanotechnology for the management of COVID-19 during the pandemic and in the post-pandemic era. National Science Review, 9(10), nwac124. [More Information]
Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., Song, H., Yang, Y., Wan, J., Yu, C. (2022). Quantum dots' size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 113892. [More Information]
Zhuang, H., Xu, C., Gao, F., Li, Y., Lei, C., Yu, C. (2022). Recent advances in silica nanomaterial assisted lateral flow assay. Bioengineering, 9(7), 266. [More Information]
Zhuang, H., Xu, C., Gao, F., Li, Y., Lei, C., Yu, C. (2022). Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay. Bioengineering, 9(7), 266. [More Information]
Cao, Y., Xu, C., Wright, P., Liu, J., Kong, Y., Wang, Y., Huang, X., Song, H., Fu, J., Gao, F., et al (2021). Calcium-Doped Silica Nanoparticles Mixed with Phosphate-Doped Silica Nanoparticles for Rapid and Stable Occlusion of Dentin Tubules. ACS Applied Nano Materials, 4, 8761-8769. [More Information]
Lei, C., Cao, Y., Hosseinpour, S., Gao, F., Liu, J., Fu, J., Staples, R., Ivanovski, S., Xu, C. (2021). Hierarchical dual porous hydroxyapatite doped dendritic mesoporous silica nanoparticles based scaffold promote osteogenesis in vitro and in vivo. Nano Research, 14(3), 770-777. [More Information]
Gao, F., Lei, C., Liu, Y., Song, H., Kong, Y., Wan, J., Yu, C. (2021). Rational Design of Dendritic Mesoporous Silica Nanoparticles’ Surface Chemistry for Quantum Dot Enrichment and an Ultrasensitive Lateral Flow Immunoassay. ACS Applied Materials and Interfaces, 13(18), 20921-22076. [More Information]
Gao, F., Liu, Y., Lei, C., Liu, C., Song, H., Gu, Z., Jiang, P., Jing, S., Wan, J., Yu, C. (2021). The Role of Dendritic Mesoporous Silica Nanoparticles' Size for Quantum Dots Enrichment and Lateral Flow Immunoassay Performance. Small Methods, 5(4), e2000924. [More Information]
Tasia, W., Lei, C., Cao, Y., Ye, Q., He, Y., Xu, C. (2020). Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles. Nanoscale, 12, 2328-2332. [More Information]
Xu, C., Xiao, L., Cao, Y., He, Y., Lei, C., Xiao, Y., Sun, W., Ahadian, S., Zhou, X., Khademhosseini, A., et al (2020). Mesoporous silica rods with cone shaped pores modulate inflammation and deliver BMP-2 for bone regeneration. Nano Research, 13(9), 2323-2331. [More Information]
Tang, J., Meka, A., Theivendran, S., Wang, Y., Yang, Y., Song, H., Fu, J., Ban, W., Gu, Z., Lei, C., et al (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062. [More Information]
Xu, C., Cao, Y., Lei, C., Li, Z., Kumeria, T., Meka, A., Xu, J., Liu, J., Yan, C., Luo, L., et al (2020). Polymer−Mesoporous Silica Nanoparticle Core−Shell Nanofibers as a Dual-Drug-Delivery System for Guided Tissue Regeneration. ACS Applied Nano Materials, 3, 1457-1467. [More Information]
Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., Wang, Y., Yang, Y., Jin, L., Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430. [More Information]
Kalantari, M., Gu, Z., Cao, Y., Lei, C., Zhang, J. (2020). Thiolated silica nanoadsorbents enable ultrahigh and fast decontamination of mercuryĲII): understanding the contribution of thiol moieties' density and accessibility on adsorption performance. Environmental Science: Nano, 7(3), 851-886. [More Information]
Kalantari, M., Ghosh, T., Liu, Y., Zhang, J., Zou, J., Lei, C., Yu, C. (2019). Highly Thiolated Dendritic Mesoporous Silica Nanoparticles with High-Content Gold as Nanozymes: The Nano-Gold Size Matters. ACS Applied Materials and Interfaces, 11(14), 13264-13272. [More Information]
Xu, C., Lei, C., Yu, C. (2019). Mesoporous silica nanoparticles for protein protection and delivery. Frontiers in Chemistry, 7(290), 1-12. [More Information]
Li, H., Guo, H., Lei, C., Liu, L., Xu, L., Feng, Y., Ke, J., Fang, W., Song, H., Xu, C., et al (2019). Nanotherapy in Joints: Increasing Endogenous Hyaluronan Production by Delivering Hyaluronan Synthase 2. Advanced Materials, 31(46), e1904535. [More Information]
Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019. [More Information]
Xu, C., Xu, J., Xiao, L., Li, Z., Xiao, Y., Dargusch, M., Lei, C., He, Y., Ye, Q. (2018). Double-layered microspheres based dual growth factors delivery system for guided bone regeneration. RSC Advances, 8(30), 16503-16512. [More Information]
Yang, Y., Tang, J., Abbaraju, P., Jambhrunkar, M., Song, H., Zhang, M., Lei, C., Fu, J., Gu, Z., Liu, Y., et al (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769. [More Information]
Yang, Y., Lu, Y., Abbaraju, P., Azimi, I., Lei, C., Tang, J., Jambhrunkar, M., Fu, J., Zhang, M., Liu, Y., et al (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1800706. [More Information]
Lin, C., Xu, C., Yang, Y., Lei, C., Zhang, H., Yu, C. (2017). Dendritic mesoporous silica–titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760. [More Information]
Sa, Y., Xiaowei, F., Lei, C., Yu, Y., Jiang, T., Wang, Y. (2017). Evaluation of the effectiveness of micro-Raman spectroscopy in monitoring the mineral contents change of human enamel in vitro. Lasers in Medical Science, 32(5), 985-991. [More Information]
Xu, C., Lei, C., Huang, L., Zhang, J., Zhang, H., Song, H., Yu, M., Wu, Y., Chen, C. (2017). Glucose-Responsive Nanosystem Mimicking the Physiological Insulin Secretion via an Enzyme–Polymer Layer-by-Layer Coating Strategy. Chemistry of Materials, 29(18), 7725-7732. [More Information]
Lei, C., Zhou, L., Xu, C., Sun, X., Nouwens, A., Yu, C. (2016). Binder-free TiO2 Monolith Packed Pipette-tips for the Enrichment of Phosphorylated Peptides. Australian Journal of Chemistry, 69(12). [More Information]
Lei, C., Xu, C., Nouwens, A., Yu, C. (2016). Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles. Journal of Materials Chemistry B, 4(29), 4975-4979. [More Information]
Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., Lei, C., Niu, Y., Huang, X., Yang, Y., et al (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955. [More Information]
Lei, C., Xu, C., Noonan, O., Meka, A., Zhang, L., Nouwens, A., Yu, C. (2015). Mesoporous materials modified by aptamers and hydrophobic groups assist ultra-sensitive insulin detection in serum. Chemical Communications, 51(71), 13642-13645. [More Information]
Lei, C., Noonan, O., Jambhrunkar, S., Qian, K., Xu, C., Zhang, J., Nouwens, A., Yu, C. (2014). Sensitive Detection of Human Insulin using a Designed Combined Pore Approach. Small, 10(12), 2413-2418. [More Information]
Xu, C., Lei, C., Meng, L., Wang, C., Song, Y. (2012). Chitosan as a barrier membrane material in periodontal tissue regeneration. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 100(5), 1435-1443. [More Information]

show 32 more

By Year

Expand all

2023

Lei, C. (2023). Nanotechnology: Paving the way for advanced healthcare and beyond. Nano TransMed, 2, 100023. [More Information]
Li, Y., Xu, C., Lei, C. (2023). The Delivery and Activation of Growth Factors Using Nanomaterials for Bone Repair. Pharmaceutics, 15(3), 1017. [More Information]

2022

Hosseinpour, S., Gomez-Cerezo, M., Cao, Y., Lei, C., Dai, H., Walsh, L., Ivanovski, S., Xu, C. (2022). A Comparative Study of Mesoporous Silica and Mesoporous Bioactive Glass Nanoparticles as Non-Viral MicroRNA Vectors for Osteogenesis. Pharmaceutics, 14(11), 2302. [More Information]
Xu, C., Lei, C., Wang, Y., Yu, C. (2022). Dendritic Mesoporous Nanoparticles: Structure, Synthesis and Properties. Angewandte Chemie - International Edition, 61(12), e202112752. [More Information]
Kong, Y., Tang, C., Lei, C., Nanjundan, A., Chen, S., Ahmed, N., Rakov, D., Du, A., Huang, X., Yu, C. (2022). Enabling two-electron redox chemistry of P-type organic cathode for high-capacity aluminium-ion batteries. Nano Energy, 102, 107727. [More Information]
Xu, C., Lei, C., Hosseinpour, S., Ivanovski, S., Walsh, L., Khademhosseini, A. (2022). Nanotechnology for the management of COVID-19 during the pandemic and in the post-pandemic era. National Science Review, 9(10), nwac124. [More Information]
Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., Song, H., Yang, Y., Wan, J., Yu, C. (2022). Quantum dots' size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 113892. [More Information]
Zhuang, H., Xu, C., Gao, F., Li, Y., Lei, C., Yu, C. (2022). Recent advances in silica nanomaterial assisted lateral flow assay. Bioengineering, 9(7), 266. [More Information]
Zhuang, H., Xu, C., Gao, F., Li, Y., Lei, C., Yu, C. (2022). Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay. Bioengineering, 9(7), 266. [More Information]

show 4 more

2021

Cao, Y., Xu, C., Wright, P., Liu, J., Kong, Y., Wang, Y., Huang, X., Song, H., Fu, J., Gao, F., et al (2021). Calcium-Doped Silica Nanoparticles Mixed with Phosphate-Doped Silica Nanoparticles for Rapid and Stable Occlusion of Dentin Tubules. ACS Applied Nano Materials, 4, 8761-8769. [More Information]
Lei, C., Cao, Y., Hosseinpour, S., Gao, F., Liu, J., Fu, J., Staples, R., Ivanovski, S., Xu, C. (2021). Hierarchical dual porous hydroxyapatite doped dendritic mesoporous silica nanoparticles based scaffold promote osteogenesis in vitro and in vivo. Nano Research, 14(3), 770-777. [More Information]
Hosseinpour, S., Nanda, A., Lei, C., Lowe, B., Ye, Q., Xu, C. (2021). Nanobiomaterials in Craniofacial Bone Regeneration. In Ramesh S. Chaughule, Rajesh Dashaputra (Eds.), Advances in Dental Implantology using Nanomaterials and Allied Technology Applications, (pp. 25-52). Switzerland: Springer Nature Switzerland AG. [More Information]
Gao, F., Lei, C., Liu, Y., Song, H., Kong, Y., Wan, J., Yu, C. (2021). Rational Design of Dendritic Mesoporous Silica Nanoparticles’ Surface Chemistry for Quantum Dot Enrichment and an Ultrasensitive Lateral Flow Immunoassay. ACS Applied Materials and Interfaces, 13(18), 20921-22076. [More Information]
Gao, F., Liu, Y., Lei, C., Liu, C., Song, H., Gu, Z., Jiang, P., Jing, S., Wan, J., Yu, C. (2021). The Role of Dendritic Mesoporous Silica Nanoparticles' Size for Quantum Dots Enrichment and Lateral Flow Immunoassay Performance. Small Methods, 5(4), e2000924. [More Information]
Cheng, N., Wen, J., Hitching, R., Lei, C., Xu, C. (2021). Tooth bioengineering and whole tooth regeneration. In Sepanta Hosseinpour, Laurence J. Walsh (Eds.), Regenerative Approaches in Dentistry. An Evidence-Based Perspective, (pp. 89-102). Switzerland: Springer. [More Information]

show 3 more

2020

Tasia, W., Lei, C., Cao, Y., Ye, Q., He, Y., Xu, C. (2020). Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles. Nanoscale, 12, 2328-2332. [More Information]
Xu, C., Xiao, L., Cao, Y., He, Y., Lei, C., Xiao, Y., Sun, W., Ahadian, S., Zhou, X., Khademhosseini, A., et al (2020). Mesoporous silica rods with cone shaped pores modulate inflammation and deliver BMP-2 for bone regeneration. Nano Research, 13(9), 2323-2331. [More Information]
Tang, J., Meka, A., Theivendran, S., Wang, Y., Yang, Y., Song, H., Fu, J., Ban, W., Gu, Z., Lei, C., et al (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062. [More Information]
Xu, C., Cao, Y., Lei, C., Li, Z., Kumeria, T., Meka, A., Xu, J., Liu, J., Yan, C., Luo, L., et al (2020). Polymer−Mesoporous Silica Nanoparticle Core−Shell Nanofibers as a Dual-Drug-Delivery System for Guided Tissue Regeneration. ACS Applied Nano Materials, 3, 1457-1467. [More Information]
Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., Wang, Y., Yang, Y., Jin, L., Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430. [More Information]
Kalantari, M., Gu, Z., Cao, Y., Lei, C., Zhang, J. (2020). Thiolated silica nanoadsorbents enable ultrahigh and fast decontamination of mercuryĲII): understanding the contribution of thiol moieties' density and accessibility on adsorption performance. Environmental Science: Nano, 7(3), 851-886. [More Information]

show 3 more

2019

Kalantari, M., Ghosh, T., Liu, Y., Zhang, J., Zou, J., Lei, C., Yu, C. (2019). Highly Thiolated Dendritic Mesoporous Silica Nanoparticles with High-Content Gold as Nanozymes: The Nano-Gold Size Matters. ACS Applied Materials and Interfaces, 11(14), 13264-13272. [More Information]
Xu, C., Lei, C., Yu, C. (2019). Mesoporous silica nanoparticles for protein protection and delivery. Frontiers in Chemistry, 7(290), 1-12. [More Information]
Li, H., Guo, H., Lei, C., Liu, L., Xu, L., Feng, Y., Ke, J., Fang, W., Song, H., Xu, C., et al (2019). Nanotherapy in Joints: Increasing Endogenous Hyaluronan Production by Delivering Hyaluronan Synthase 2. Advanced Materials, 31(46), e1904535. [More Information]

2018

Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019. [More Information]
Xu, C., Xu, J., Xiao, L., Li, Z., Xiao, Y., Dargusch, M., Lei, C., He, Y., Ye, Q. (2018). Double-layered microspheres based dual growth factors delivery system for guided bone regeneration. RSC Advances, 8(30), 16503-16512. [More Information]
Yang, Y., Tang, J., Abbaraju, P., Jambhrunkar, M., Song, H., Zhang, M., Lei, C., Fu, J., Gu, Z., Liu, Y., et al (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769. [More Information]
Yang, Y., Lu, Y., Abbaraju, P., Azimi, I., Lei, C., Tang, J., Jambhrunkar, M., Fu, J., Zhang, M., Liu, Y., et al (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1800706. [More Information]

show 1 more

2017

Lin, C., Xu, C., Yang, Y., Lei, C., Zhang, H., Yu, C. (2017). Dendritic mesoporous silica–titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760. [More Information]
Sa, Y., Xiaowei, F., Lei, C., Yu, Y., Jiang, T., Wang, Y. (2017). Evaluation of the effectiveness of micro-Raman spectroscopy in monitoring the mineral contents change of human enamel in vitro. Lasers in Medical Science, 32(5), 985-991. [More Information]
Xu, C., Lei, C., Huang, L., Zhang, J., Zhang, H., Song, H., Yu, M., Wu, Y., Chen, C. (2017). Glucose-Responsive Nanosystem Mimicking the Physiological Insulin Secretion via an Enzyme–Polymer Layer-by-Layer Coating Strategy. Chemistry of Materials, 29(18), 7725-7732. [More Information]

2016

Lei, C., Zhou, L., Xu, C., Sun, X., Nouwens, A., Yu, C. (2016). Binder-free TiO2 Monolith Packed Pipette-tips for the Enrichment of Phosphorylated Peptides. Australian Journal of Chemistry, 69(12). [More Information]
Lei, C., Xu, C., Nouwens, A., Yu, C. (2016). Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles. Journal of Materials Chemistry B, 4(29), 4975-4979. [More Information]

2015

Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., Lei, C., Niu, Y., Huang, X., Yang, Y., et al (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955. [More Information]
Lei, C., Xu, C., Noonan, O., Meka, A., Zhang, L., Nouwens, A., Yu, C. (2015). Mesoporous materials modified by aptamers and hydrophobic groups assist ultra-sensitive insulin detection in serum. Chemical Communications, 51(71), 13642-13645. [More Information]

2014

Lei, C., Noonan, O., Jambhrunkar, S., Qian, K., Xu, C., Zhang, J., Nouwens, A., Yu, C. (2014). Sensitive Detection of Human Insulin using a Designed Combined Pore Approach. Small, 10(12), 2413-2418. [More Information]

2012

Xu, C., Lei, C., Meng, L., Wang, C., Song, Y. (2012). Chitosan as a barrier membrane material in periodontal tissue regeneration. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 100(5), 1435-1443. [More Information]

Selected Grants

2024

FMH Start-up Scheme, Lei C, Faculty of Medicine and Health/New Academic Staff Funding

Further Grants

(2024) ARC DECRA, Australian Research Council
(2024) DVCR scheme, University of Sydney
(2022) Australian Dental Research Fund research grants, Australian Dental Research Fund Inc
(2021) UQ Amplify fellowship, The University of Queensland
(2017) Advanced Queensland Research Fellowship, Queensland Government