People_
Dr Charles Bailey
Senior Research Fellow
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology
Cancer
Project title | Research student |
---|---|
Understanding mesothelin biology and function to enhance the efficacy of MSLN-targeted therapies against pancreatic cancer | Shuwen YE |
Publications
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Journals
- Thavaneswaran, S., Kansara, M., Lin, F., Espinoza, D., Grady, J., Lee, C., Ballinger, M., Sebastian, L., Corpuz, T., Qiu, M., Bailey, C., Schmitz, U., Simes, R., et al (2023). A signal-seeking Phase 2 study of olaparib and durvalumab in advanced solid cancers with homologous recombination repair gene alterations. British Journal of Cancer, 129(3), 475-485. [More Information]
- Treleaven, T., Zada, M., Nagarajah, R., Bailey, C., Rasko, J., Morris, M., Day, M. (2023). Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B0AT1 Is Required for Optimal Preimplantation Embryo Development in Mice. Cells, 12(1), 18. [More Information]
- Mallik, S., Bailey, C., Rasko, J. (2022). Approved gene therapies in Australia: coming to a store near you. Internal Medicine Journal, 52(8), 1313-1321. [More Information]
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Conferences
- Gottlieb, D., Garnvrellis, A., Marangolo, M., Bartlett, A., Sartor, M., Bailey, C., Rasko, J. (2006). Interleukin-12, interleukin-15 and interleukin-21 induce the expansion of normal peripheral blood mononuclear cells exposed to human acute myeloid leukaemia and their production of interferon-gamma. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
- Day, M., Bailey, C., Rasko, J., Johnson, M., Cook, D. (2005). Maintenance of potassium channel activity prevents cell division in the mouse preimplantation embryo. The Society for the Study of Reproduction 38th Annual Meeting (SSR 2005), Kansas, USA: Allen Press Inc.
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2023
- Thavaneswaran, S., Kansara, M., Lin, F., Espinoza, D., Grady, J., Lee, C., Ballinger, M., Sebastian, L., Corpuz, T., Qiu, M., Bailey, C., Schmitz, U., Simes, R., et al (2023). A signal-seeking Phase 2 study of olaparib and durvalumab in advanced solid cancers with homologous recombination repair gene alterations. British Journal of Cancer, 129(3), 475-485. [More Information]
- Treleaven, T., Zada, M., Nagarajah, R., Bailey, C., Rasko, J., Morris, M., Day, M. (2023). Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B0AT1 Is Required for Optimal Preimplantation Embryo Development in Mice. Cells, 12(1), 18. [More Information]
2022
- Mallik, S., Bailey, C., Rasko, J. (2022). Approved gene therapies in Australia: coming to a store near you. Internal Medicine Journal, 52(8), 1313-1321. [More Information]
- Sharifi Tabar, M., Parsania, C., Chen, H., Su, X., Bailey, C., Rasko, J. (2022). Illuminating the dark protein-protein interactome. Cell Reports Methods, 2(8). [More Information]
- Sharifi Tabar, M., Francis, H., Yeo, D., Bailey, C., Rasko, J. (2022). Mapping oncogenic protein interactions for precision medicine. International Journal of Cancer, 151(1), 2019-07-01 00:00:00. [More Information]
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2021
- Xi, C., Di Fazio, A., Nadvi, N., Xiang, M., Zhang, H., Deshpande, C., Chen, Y., Sharifi Tabar, M., Wang, X., Bailey, C., McCaughan, G., Church, W., Gorrell, M. (2021). An improved production and purification protocol for recombinant soluble human fibroblast activation protein alpha. Protein Expression and Purification, 181, 1-8. [More Information]
- Alharbi, A., Schmitz, U., Bailey, C., Rasko, J. (2021). CTCF as a regulator of alternative splicing: new tricks for an old player. Nucleic Acids Research, 49(14), 7825-7838. [More Information]
- Alharbi, A., Schmitz, U., Marshall, A., Vanichkina, D., Nagarajah, R., Vellozzi, M., Wong, J., Bailey, C., Rasko, J. (2021). Ctcf haploinsufficiency mediates intron retention in a tissue-specific manner. RNA Biology, 18(1), 93-103. [More Information]
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2020
- Schmitz, U., Shah, J., Dhungel, B., Monteuuis, G., Luu, P., Petrova, V., Metierre, C., Nair, S., Bailey, C., Saunders, V., Wong, J., Rasko, J., et al (2020). Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukaemia patients. Cancers, 12(12), 1-19. [More Information]
2019
- Zhang, B., Moran, A., Bailey, C., Rasko, J., Holst, J., Wang, Q. (2019). EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer. Cell Communication and Signaling, 17(1), 1-11. [More Information]
- Zhang, H., Hamson, E., Koczorowska, M., Tholen, S., Chowdhury, S., Bailey, C., Lay, A., Twigg, S., Lee, Q., Roediger, B., O'Rourke, M., McCaughan, G., Keane, F., Gorrell, M., et al (2019). Identification of novel natural substrates of fibroblast activation protein-alpha by differential degradomics and proteomics. Molecular and Cellular Proteomics, 18(1), 65-85. [More Information]
- Susanto, A., Zhao, G., Wazin, F., Feng, Y., Rasko, J., Bailey, C., Lovicu, F. (2019). Spred negatively regulates lens growth by modulating epithelial cell proliferation and fiber differentiation. Experimental Eye Research, 178, 160-175. [More Information]
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2018
- Bailey, C., Metierre, C., Feng, Y., Baidya, K., Filippova, G., Loukinov, D., Lobanenkov, V., Semaan, C., Rasko, J. (2018). CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer. International Journal of Molecular Sciences, 19(12), 1-20. [More Information]
- Sandt, C., Feraud, O., Bonnet, M., Desterke, C., Khedhir, R., Flamant, S., Bailey, C., Rasko, J., Dumas, P., Bennaceur-Griscelli, A., et al (2018). Direct and rapid identification of T315I-Mutated BCR-ABL expressing leukemic cells using infrared microspectroscopy. Biochemical and Biophysical Research Communications, 503(3), 1861-1867. [More Information]
- Rajasekhar, M., Schmitz, U., Flamant, S., Wong, J., Bailey, C., Ritchie, W., Holst, J., Rasko, J. (2018). Identifying microRNA determinants of human myelopoiesis. Scientific Reports, 8(1), 1-15. [More Information]
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2017
- Marshall, A., Bailey, C., Champ, K., Vellozzi, M., O’Young, P., Metierre, C., Feng, Y., Thoeng, A., Richards, A., Schmitz, U., Biro, M., Anderson, L., Rasko, J., et al (2017). CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. Oncogene, 36(29), 4100-4110. [More Information]
- Guan, F., Bailey, C., Metierre, C., O’Young, P., Gao, D., Khoo, T., Holst, J., Rasko, J. (2017). The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo. Journal of Hematology and Oncology, 10(1), 1-17. [More Information]
2016
- van Geldermalsen, M., Wang, Q., Nagarajah, R., Marshall, A., Thoeng, A., Gao, D., Ritchie, W., Feng, Y., Bailey, C., Deng, N., Beith, J., O'Toole, S., Rasko, J., Holst, J., et al (2016). ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene, 35(24), 3201-3208. [More Information]
- Liu, H., Ooms, L., Srijakotre, N., Man, J., Vieusseux, J., Waters, J., Feng, Y., Bailey, C., Rasko, J., Price, J., et al (2016). PtdIns(3,4,5)P3-dependent rac exchanger 1 (PREX1) rac-guanine nucleotide exchange factor (GEF) activity promotes breast cancer cell proliferation and tumor growth via activation of extracellular signal-regulated kinase 1/2 (ERK1/2) signaling. Journal of Biological Chemistry, 291(33), 17258-17270. [More Information]
- Wong, J., Au, A., Gao, D., Pinello, N., Kwok, C., Thoeng, A., Lau, K., Gordon, J., Schmitz, U., Feng, Y., Nguyen, T., Middleton, R., Bailey, C., Holst, J., Rasko, J., Ritchie, W. (2016). RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever. Nucleic Acids Research, 44(6), 2888-2897. [More Information]
2015
- Wang, Q., Hardie, R., Hoy, A., van Geldermalsen, M., Gao, D., Fazli, L., Sadowski, M., Balaban, S., Schreuder, M., Nagarajah, R., Wong, J., Metierre, C., Pinello, N., Otte, N., Bailey, C., Ritchie, W., Rasko, J., Holst, J., et al (2015). Targeting ASCT2-Mediated Glutamine Uptake Blocks Prostate Cancer Growth and Tumour Development. Journal of Pathology, 236(3), 278-289. [More Information]
2014
- Marshall, A., Bailey, C., Rasko, J. (2014). CTCF and BORIS in genome regulation and cancer. Current Opinion in Genetics & Development, 24, 8-15. [More Information]
- Wang, Q., Grkovic, T., Font Sadurni, J., Bonham, S., Pouwer, R., Bailey, C., Moran, A., Ryan, R., Rasko, J., Jormakka, M., Holst, J., et al (2014). Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth. ACS Chemical Biology, 9(6), 1369-1376. [More Information]
- Clancy, J., Patel, H., Hussein, S., Tonge, P., Cloonan, N., Corso, A., Li, M., Lee, D., Shin, J., Wong, J., Bailey, C., Rasko, J., et al (2014). Small RNA changes en route to distinct cellular states of induced pluripotency. Nature Communications, 5, 1-9. [More Information]
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2013
- Wong, J., Ritchie, W., Ebner, O., Selbach, M., Wong, J., Huang, Y., Gao, D., Pinello, N., Gonzalez, M., Baidya, K., Thoeng, A., Khoo, T., Bailey, C., Holst, J., Rasko, J. (2013). Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation. Cell, 154(3), 583-595. [More Information]
- Gall, M., Chen, Y., Vieira de Ribeiro, A., Zhang, H., Bailey, C., Spielman, D., Yu, M., Gorrell, M. (2013). Targeted Inactivation of Dipeptidyl Peptidase 9 Enzymatic Activity Causes Mouse Neonate Lethality. PloS One, 8(11), 1-10. [More Information]
- Wang, Q., Tiffen, J., Bailey, C., Lehman, M., Ritchie, W., Fazli, L., Metierre, C., Feng, Y., Li, E., Gleave, M., Rasko, J., Holst, J., et al (2013). Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. Journal of the National Cancer Institute, 105(19), 1463-1473. [More Information]
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2011
- Wang, Q., Bailey, C., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M., Hendy, S., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2011). Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression. Cancer Research, 71(24), 7525-7536. [More Information]
- Balamatsias, D., Kong, A., Waters, J., Sriratana, A., Gurung, R., Bailey, C., Rasko, J., Tiganis, T., Macaulay, S., Mitchell, C. (2011). Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes. Journal of Biological Chemistry, 286(50), 43229-43240. [More Information]
- Broer, A., Juelich, T., Vanslambrouck, J., Tietze, N., Solomon, P., Holst, J., Bailey, C., Rasko, J., Broer, S. (2011). Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. Journal of Biological Chemistry, 286(30), 26638-26651. [More Information]
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2010
- Einecke, G., Kayser, D., Vanslambrouck, J., Sis, B., Reeve, J., Mengel, M., Famulski, K., Bailey, C., Rasko, J., Halloran, P. (2010). Loss of solute carriers in T cell-mediated rejection in mouse and human kidneys: an active epithelial injury-repair response. American Journal Of Transplantation, 10(10), 2241-2251. [More Information]
- Tiffen, J., Bailey, C., Ng, C., Rasko, J., Holst, J. (2010). Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo. Molecular Cancer, 9, 299-1-299-8. [More Information]
- Broer, A., Vanslambrouck, J., Thavyogarajah, T., Holst, J., Bailey, C., Broer, S., Rasko, J. (2010). Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria. Biochemical Journal, 428(3), 397-407. [More Information]
2008
- Bröer, S., Bailey, C., Kowalczuk, S., Ng, C., Vanslambrouck, J., Rodgers, H., Auray-Blais, C., Cavanaugh, J., Bröer, A., Rasko, J. (2008). Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. Journal of Clinical Investigation, 118(12), 3881-3892. [More Information]
2007
- Azmanov, D., Rodgers, H., Auray-Blais, C., Giguere, R., Bailey, C., Broer, S., Rasko, J., Cavanaugh, J. (2007). Persistence of the common Hartnup disease D173N allele in populations of European origin. Annals of Human Genetics, 71(6), 755-761. [More Information]
- Horan, K., Watanabe, K., Kong, A., Bailey, C., Rasko, J., Sasaki, T., Mitchell, C. (2007). Regulation of FcgammaR-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3-mediated phagocytosis by differential recruitment of these 5-phosphatases to the phagocytic cup. Blood, 110(13), 4480-4491. [More Information]
2006
- Gottlieb, D., Garnvrellis, A., Marangolo, M., Bartlett, A., Sartor, M., Bailey, C., Rasko, J. (2006). Interleukin-12, interleukin-15 and interleukin-21 induce the expansion of normal peripheral blood mononuclear cells exposed to human acute myeloid leukaemia and their production of interferon-gamma. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
- Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Bailey, C., Rasko, J., Allen, D., Semsarian, C. (2006). Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 41(4), 623-632. [More Information]
- Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Rasko, J., Bailey, C., Allen, D., Semsarian, C. (2006). Mouse cardiac troponin I model of hypertrophic cardiomyopathy: Phenotype associated with abnormal calcium handling. Journal of Molecular and Cellular Cardiology, 41(4), 747 (abstract 41)-747.
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2005
- Day, M., Bailey, C., Rasko, J., Johnson, M., Cook, D. (2005). Maintenance of potassium channel activity prevents cell division in the mouse preimplantation embryo. The Society for the Study of Reproduction 38th Annual Meeting (SSR 2005), Kansas, USA: Allen Press Inc.
2004
- Seow, F., Broer, S., Broer, A., Bailey, C., Potter, S., Cavanaugh, J., Rasko, J. (2004). Hartnup Disorder Is Caused By Mutations In The Gene Encoding The Neutral Amino Acid Transporter Slc6A19. Nature Genetics, 36(9), 1003-1007. [More Information]
Selected Grants
2023
- Exploiting ZNF185 as a new therapeutic vulnerability in pancreatic cancer, Bailey C, Tour de Cure Ltd/Research Matching Grant
2022
- A better prognostic marker and new therapeutic opportunities for pancreatic cancer, Bailey C, Tour de Cure Ltd/Pioneering Research Grant
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